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Volumn 151, Issue 4, 2004, Pages 483-489

Insulin resistance and endothelial function are improved after folate and vitamin B12 therapy in patients with metabolic syndrome: Relationship between homocysteine levels and hyperinsulinemia

Author keywords

[No Author keywords available]

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM ANTAGONIST; CYANOCOBALAMIN; CYCLIC GMP; DIMETHYLARGININASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; FOLIC ACID; HOMOCYSTEINE; INSULIN; ISOSORBIDE DINITRATE; PLACEBO;

EID: 7244231126     PISSN: 08044643     EISSN: None     Source Type: Journal    
DOI: 10.1530/eje.0.1510483     Document Type: Article
Times cited : (141)

References (44)
  • 2
    • 0018858624 scopus 로고
    • Homocysteine-induced endothelial cell injury in vitro: A model for the study of vascular injury
    • Wall RT, Harlan JM, Harker LA & Striker GE. Homocysteine-induced endothelial cell injury in vitro: a model for the study of vascular injury. Thrombosis Research 1980 18 113-121.
    • (1980) Thrombosis Research , vol.18 , pp. 113-121
    • Wall, R.T.1    Harlan, J.M.2    Harker, L.A.3    Striker, G.E.4
  • 4
    • 0031018333 scopus 로고    scopus 로고
    • Hyperhomocyst(e)inemia is associated with impaired endothelium-dependent vasodilation in humans
    • Tawakol A, Omland T, Gerhard M, Wu J & Creager MA. Hyperhomocyst(e)inemia is associated with impaired endothelium-dependent vasodilation in humans. Circulation 1997 95 1119-1121.
    • (1997) Circulation , vol.95 , pp. 1119-1121
    • Tawakol, A.1    Omland, T.2    Gerhard, M.3    Wu, J.4    Creager, M.A.5
  • 8
    • 0035960677 scopus 로고    scopus 로고
    • Endothelial dysfunction, oxidative stress, and risk of cardiovascular events in patients with coronary artery disease
    • Heitzer T, Schlinzig T, Krohn K, Meinertz T & Munzel T. Endothelial dysfunction, oxidative stress, and risk of cardiovascular events in patients with coronary artery disease. Circulation 2001 104 2673-2678.
    • (2001) Circulation , vol.104 , pp. 2673-2678
    • Heitzer, T.1    Schlinzig, T.2    Krohn, K.3    Meinertz, T.4    Munzel, T.5
  • 9
    • 0029805172 scopus 로고    scopus 로고
    • Nitric oxide, superoxide, and peroxynitrite: The good, the bad, and ugly
    • Beckman JS & Koppenol WH. Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. American Journal of Physiology 1996 271 C1424-C1433.
    • (1996) American Journal of Physiology , vol.271
    • Beckman, J.S.1    Koppenol, W.H.2
  • 11
    • 0035806914 scopus 로고    scopus 로고
    • Polic acid prevents nitroglycerin-induced nitric oxide synthase dysfunction and nitrate tolerance: A human in vivo study
    • Gori T, Burnstein JM, Ahmed S, Miner SE, Al Hesayen A, Kelly S & Parker JD. Polic acid prevents nitroglycerin-induced nitric oxide synthase dysfunction and nitrate tolerance: a human in vivo study. Circulation 2001 104 1119-1123.
    • (2001) Circulation , vol.104 , pp. 1119-1123
    • Gori, T.1    Burnstein, J.M.2    Ahmed, S.3    Miner, S.E.4    Al Hesayen, A.5    Kelly, S.6    Parker, J.D.7
  • 14
    • 3042646937 scopus 로고    scopus 로고
    • Distribution of serum total homocysteine and its association with diabetes and cardiovascular risk factors of the insulin resistance syndrome in Mexican American men: The Third National Health and Nutrition Examination Survey
    • Gillum R. Distribution of serum total homocysteine and its association with diabetes and cardiovascular risk factors of the insulin resistance syndrome in Mexican American men: the Third National Health and Nutrition Examination Survey. Nutrition Journal 2003 2 6-13.
    • (2003) Nutrition Journal , vol.2 , pp. 6-13
    • Gillum, R.1
  • 17
    • 0037372930 scopus 로고    scopus 로고
    • Insulin sensitivity and plasma homocysteine concentrations in non diabetic obese and normal weight subjects
    • Fonseca VA, Fink LM & Kern PA. Insulin sensitivity and plasma homocysteine concentrations in non diabetic obese and normal weight subjects. Atherosclerosis 2003 167 105-109.
    • (2003) Atherosclerosis , vol.167 , pp. 105-109
    • Fonseca, V.A.1    Fink, L.M.2    Kern, P.A.3
  • 18
    • 0345375263 scopus 로고    scopus 로고
    • Hyperhomocysteinemia as a component of syndrome X
    • Oron-Herman M, Rosenthal T & Sela BA. Hyperhomocysteinemia as a component of syndrome X. Metabolism 2003 52 1491-1495.
    • (2003) Metabolism , vol.52 , pp. 1491-1495
    • Oron-Herman, M.1    Rosenthal, T.2    Sela, B.A.3
  • 19
    • 0037385778 scopus 로고    scopus 로고
    • Insulin resistance in patients with polycystic ovary syndrome is associated with elevated plasma homocysteine
    • Schachter M, Raziel A, Friedler S, Strassburger D, Bern O & Ron-El R. Insulin resistance in patients with polycystic ovary syndrome is associated with elevated plasma homocysteine. Human Reproduction 2003 18 721-727.
    • (2003) Human Reproduction , vol.18 , pp. 721-727
    • Schachter, M.1    Raziel, A.2    Friedler, S.3    Strassburger, D.4    Bern, O.5    Ron-El, R.6
  • 20
    • 0033049262 scopus 로고    scopus 로고
    • Plasma homocysteine levels elevated and inversely related to insulin sensitivity in preeclampsia
    • Laivuori H, Kaaja R, Turpeinen U, Viinikka L & Ylikorkala O. Plasma homocysteine levels elevated and inversely related to insulin sensitivity in preeclampsia. Obstetrics and Gynecology 1999 93 489-493.
    • (1999) Obstetrics and Gynecology , vol.93 , pp. 489-493
    • Laivuori, H.1    Kaaja, R.2    Turpeinen, U.3    Viinikka, L.4    Ylikorkala, O.5
  • 21
    • 0032779879 scopus 로고    scopus 로고
    • Plasma homocysteine concentrations in healthy volunteers are not related to differences in insulin mediated glucose disposal
    • Abbasi F, Facchini F, Humphreys MH & Reaven GM. Plasma homocysteine concentrations in healthy volunteers are not related to differences in insulin mediated glucose disposal. Atherosclerosis 1999 146 175-178.
    • (1999) Atherosclerosis , vol.146 , pp. 175-178
    • Abbasi, F.1    Facchini, F.2    Humphreys, M.H.3    Reaven, G.M.4
  • 22
    • 0242351811 scopus 로고    scopus 로고
    • Effects of short-term treatment with metformin on serum concentrations of homocysteine, folate and vitamin B12 in type 2 diabetes mellitus: A randomized, placebo-controlled trial
    • Wulfelle MG, Kooy A, Lehert P, Bets D, Ogterop JC, Borger van de Burg B, Donker AJ & Stehouwer CD. Effects of short-term treatment with metformin on serum concentrations of homocysteine, folate and vitamin B12 in type 2 diabetes mellitus: a randomized, placebo-controlled trial. Journal of Internal Medicine 2003 254 455-463.
    • (2003) Journal of Internal Medicine , vol.254 , pp. 455-463
    • Wulfelle, M.G.1    Kooy, A.2    Lehert, P.3    Bets, D.4    Ogterop, J.C.5    Borger van de Burg, B.6    Donker, A.J.7    Stehouwer, C.D.8
  • 23
    • 0042168681 scopus 로고    scopus 로고
    • Improved insulin sensitivity and metabolic control in type 2 diabetes does not influence plasma homocysteine
    • Pouwels MJ, Den Heijer M, Blom HJ, Tack CJ & Hermus AR. Improved insulin sensitivity and metabolic control in type 2 diabetes does not influence plasma homocysteine. Diabetes Care 2003 26 1637-1639.
    • (2003) Diabetes Care , vol.26 , pp. 1637-1639
    • Pouwels, M.J.1    Den Heijer, M.2    Blom, H.J.3    Tack, C.J.4    Hermus, A.R.5
  • 24
    • 0036105569 scopus 로고    scopus 로고
    • Insulin increases homocysteine levels in a dose dependent manner in diabetic rats
    • Gursu MF, Baydas G, Cikim G & Canatan H. Insulin increases homocysteine levels in a dose dependent manner in diabetic rats. Archives of Medical Research 2002 33 305-307.
    • (2002) Archives of Medical Research , vol.33 , pp. 305-307
    • Gursu, M.F.1    Baydas, G.2    Cikim, G.3    Canatan, H.4
  • 25
    • 0035897696 scopus 로고    scopus 로고
    • Executive summary of the third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation and Treatment of high blood cholesterol in Adults (Adult Treatment Panel III)
    • Expert Panel on Detection Evaluation and Treatment of High Blood Cholesterol in Adults
    • Expert Panel on Detection Evaluation and Treatment of High Blood Cholesterol in Adults. Executive summary of the third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation and Treatment of high blood cholesterol in Adults (Adult Treatment Panel III). Journal of the American Medical Association 2001 285 2486-2497.
    • (2001) Journal of the American Medical Association , vol.285 , pp. 2486-2497
  • 28
    • 0021813187 scopus 로고
    • Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentration in man
    • Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF & Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentration in man. Diabetologia 1985 28 412-419.
    • (1985) Diabetologia , vol.28 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3    Naylor, B.A.4    Treacher, D.F.5    Turner, R.C.6
  • 29
    • 0037469213 scopus 로고    scopus 로고
    • Acute intravenous L-arginine infusion decreases endothelin-1 levels and improves endothelial function in patients with angina pectoris and normal coronary arteriograms
    • Piatti PM, Fragasso G, Monti LD, Setola E, Lucotti P, Fermo I, Paroni R, Galluccio E, Pozza G, Chierchia S & Margonato A. Acute intravenous L-arginine infusion decreases endothelin-1 levels and improves endothelial function in patients with angina pectoris and normal coronary arteriograms. Circulation 2003 107 429-436.
    • (2003) Circulation , vol.107 , pp. 429-436
    • Piatti, P.M.1    Fragasso, G.2    Monti, L.D.3    Setola, E.4    Lucotti, P.5    Fermo, I.6    Paroni, R.7    Galluccio, E.8    Pozza, G.9    Chierchia, S.10    Margonato, A.11
  • 31
    • 0034882792 scopus 로고    scopus 로고
    • Homocysteine thiolactone inhibits insulin signaling, and glutathione has a protective effect
    • Najib S & Sanchez-Margalet V. Homocysteine thiolactone inhibits insulin signaling, and glutathione has a protective effect. Journal of Molecular Endocrinology 2001 27 85-91.
    • (2001) Journal of Molecular Endocrinology , vol.27 , pp. 85-91
    • Najib, S.1    Sanchez-Margalet, V.2
  • 34
    • 0033859798 scopus 로고    scopus 로고
    • Insulin is an independent correlate of plasma homocysteine levels in obese children and adolescents
    • Gallistl S, Sudi K, Mangge H, Erwa W & Borkenstein M. Insulin is an independent correlate of plasma homocysteine levels in obese children and adolescents. Diabetes Care 2000 23 1348-1352.
    • (2000) Diabetes Care , vol.23 , pp. 1348-1352
    • Gallistl, S.1    Sudi, K.2    Mangge, H.3    Erwa, W.4    Borkenstein, M.5
  • 37
    • 0345103740 scopus 로고    scopus 로고
    • Folic acid treatment reduces elevated plasma levels of asymmetric dimethylarginine in hyperhomocysteinaemic subjects
    • Holven KB, Haugstad TS, Holm T, Aukrust P, Ose L & Nenseter MS. Folic acid treatment reduces elevated plasma levels of asymmetric dimethylarginine in hyperhomocysteinaemic subjects. British Journal of Nutrition 2003 89 359-363.
    • (2003) British Journal of Nutrition , vol.89 , pp. 359-363
    • Holven, K.B.1    Haugstad, T.S.2    Holm, T.3    Aukrust, P.4    Ose, L.5    Nenseter, M.S.6
  • 39
    • 0035923560 scopus 로고    scopus 로고
    • Homocysteine impairs the nitric oxide synthase pathway. Role of asymmetric dimethylarginine
    • Stühlinger M, Tsao PS, Her JH, Kimoto M, Balint RF & Cooke JP. Homocysteine impairs the nitric oxide synthase pathway. Role of asymmetric dimethylarginine. Circulation 2001 104 2569-2575.
    • (2001) Circulation , vol.104 , pp. 2569-2575
    • Stühlinger, M.1    Tsao, P.S.2    Her, J.H.3    Kimoto, M.4    Balint, R.F.5    Cooke, J.P.6
  • 44
    • 0036140785 scopus 로고    scopus 로고
    • Folic acid improves endothelial function in coronary artery disease via mechanisms largely independent of homocysteine lowering
    • Doshi SN, McDowell IF, Moat SJ, Payne N, Durrant HJ, Lewis MJ & Goodfellow J. Folic acid improves endothelial function in coronary artery disease via mechanisms largely independent of homocysteine lowering. Circulation 2002 105 22-26.
    • (2002) Circulation , vol.105 , pp. 22-26
    • Doshi, S.N.1    McDowell, I.F.2    Moat, S.J.3    Payne, N.4    Durrant, H.J.5    Lewis, M.J.6    Goodfellow, J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.