Induction of cyclin A gene expression by homocysteine in vascular smooth muscle cells

Journal of Clinical Investigation

Volumn 97, Issue 1, 1996, Pages 146-153

  Tsai, Jer Chia ^a,d   Wang, Hong ^a   Perrella, Mark A ^a,b,c   Yoshizumi, Masao ^a,b   Sibinga, Nicholas E S ^a,b,c   Tan, Larissa C ^a   Haber, Edgar ^a,b,c   Chang, Ted Hung Tse ^a   Schlegel, Robert ^a   Lee, Mu En ^a,b,c  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

atherosclerosis; cell cycle; gene regulation; myocardial infarction; transcription

Indexed keywords

CYCLIN A; CYCLIN DEPENDENT KINASE; DNA BINDING PROTEIN; HOMOCYSTEINE;

ANIMAL CELL; ARTICLE; DNA PROTEIN COMPLEX; DNA SYNTHESIS; FETAL CALF SERUM; GENE INDUCTION; HALF LIFE TIME; HUMAN; HUMAN CELL; MALE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RAT; TRANSCRIPTION REGULATION; VASCULAR SMOOTH MUSCLE;

EID: 13344270367     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118383     Document Type: Article

References (37)

1. Ross, R. 1993. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature (Lond). 362:801-809.
2. Stampfer, M. J., and M. R. Malinow. 1995. Can lowering homocysteine levels reduce cardiovascular risk? N. Engl. J. Med. 332:328-329.
3. Malinow, M R. 1990. Hyperhomocyst(e)inemia. A common and easily reversible risk factor for occlusive atherosclerosis. Circulation 81:2004-2006.
4. Stampfer, M. J., and W. C. Willett. 1993. Homocysteine and marginal vitamin deficiency. The importance of adequate vitamin intake. J. Am. Med Assoc 270:2726-2727.
5. Ueland, P M., and H. Refsum. 1993. Plasma homocysteine, a risk factor for vascular disease: plasma levels in health, disease, and drug therapy J Lab. Clin Med. 114:473-501.
6. Malinow, M. R., F. J. Nieto, M Szklo, L. E. Chambless, and G. Bond. 1993. Carotid artery intimal-medial wall thickening and plasma homocyst(e)ine in asymptomatic adults. The Atherosclerosis Risk in Communities Study. Circulation. 87:1107-1113.
7. Clarke, R , L. Daly, K Robinson, E. Naughten, S. Cahalane, B. Fowler, and I. Graham 1991. Hyperhomocysteinemia: an independent risk factor for vascular disease. N Engl J. Med. 324:1149-1155.
8. Boers, G. H. J., A. G. H. Smals, F. J. M. Trijbels, B Fowler, J. A J. M. Bakkeren, H. C Schoonderwaldt, W J. Kleijer, and P. W. C. Koppenborg. 1985. Heterozygosity for homocystinuria in premature peripheral and cerebral occlusive arterial disease. N. Engl. J Med 313:709-715.
9. Coull, B. M., M. R. Malinow, N. Beamer, G. Sexton, F. Nordt, and P. de Garmo. 1990. Elevated plasma homocyst(e)ine concentration as a possible independent risk factor for stroke. Stroke. 21:572-576.
10. Stampfer, M. J., R Malinow, W. C. Willett, L. M. Newcomer, B. Upson, D. Ullman, P. V. Tishler, and C H. Hennekens. 1992. A prospective study of plasma homocyst(e)ine and risk of myocardial infarction in US physicians. J. Am Med. Assoc. 268:877-881.
11. Selhub, J., P. F. Jacques, P. W. Wilson, D. Rush, and I. H. Rosenberg. 1993. Vitamin status and intake as primary determinants of homocystememia in an elderly population. J. Am Med. Assoc 270:2693-2698.
12. Selhub, J., P F Jacques, A. G. Bostom, R. B. D'Agostino, P. W F.Wilson. A J Belanger, D. H. O'Leary, P. A. Wolf, E. J. Schaefer, and I. H. Rosenberg. 1995. Association between plasma homocysteine concentrations and extracranial carotid-artery stenosis. N. Engl. J Med. 332:286-291.
13. Rodgers, G. M., and M. T. Conn. 1990 Homocysteine, an atherogenic stimulus, reduces protein C activation by arterial and venous endothelial cells Blood. 75:895-901.
14. Lentz, S R., and J. E Sadler 1993. Homocysteine inhibits von Willebrand factor processing and secretion by preventing transport from the endoplasmic reticulum. Blood. 81:683-689.
15. Hajjar, K. A. 1993 Homocysteine-induced modulation of tissue plasminogen activator binding to its endothelial cell membrane receptor. J. Clin. Invest 91:2873-2879.
16. Stamler, J. S., J. A Osborne, O. Jaraki, L. E. Rabbani, M Mullins, D. Singel, and J. Loscalzo. 1993. Adverse vascular effects of humocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen. J Clin. Invest. 91:308-318.
17. Schwartz, S M., R. L. Heimark, and M. W Majesky. 1990. Developmental mechanisms underlying pathology of arteries. Physiol Rev 70:1177-1209.
18. Tsai, J. C., M A. Perrella, M. Yoshizumi, C. M. Hsieh, E. Haber, R. Schlegel, and M E. Lee. 1994. Promotion of vascular smooth muscle cell growth by homocysteine: a link to atherosclerosis. Proc. Natl. Acad Sci USA. 91:6369-6373.
19. Dou, Q. P., A. H. Levin, S. Zhao, and A. B Pardee. 1993. Cyclin E and cyclin A as candidates for the restriction point protein. Cancer Res. 53:1493-1497.
20. Yoshizumi, M., W.-S. Lee, C.-M. Hsieh, J.-C. Tsai, J. Li, M. A. Perrella, C. Patterson, W. O. Endege, R. Schlegel, and M.-E. Lee 1995. Disappearance of cyclin A correlates with permanent withdrawal of cardiomyocytes from the cell cycle in human and rat hearts. J. Clin. Invest 95:2275-2280.
21. Pagano, M., R. Pepperkok, F. Verde, W. Ansorge, and G. Draetta. 1992. Cyclin A is required at two points in the human cell cycle. EMBO (Eur. Mol Biol Organ.) J. 11:961-971.
22. Girard, F., U. Strausfeld, A. Fernandez, and N. J. Lamb. 1991. Cyclin A is required for the onset of DNA replication in mammalian fibroblasts Cell. 67: 1169-1179
23. Sobczak, T. J., F. Harper, Y. Florentin, F. Zindy, C. Brechot, and E. Puvion. 1993. Localization of cyclin A at the sites of cellular DNA replication. Exp. Cell Res 206:43-48.
24. Gunther, S., R. W. Alexander, W. J. Atkinson. and M. A. Gimbrone, Jr 1982. Functional angiotensin II receptors in cultured vascular smooth muscle cells J. Cell Biol 92:289-298.
25. Perrella, M. A., M. Yoshizumi, Z. Fen, J -C. Tsai, C.-M. Hsieh, S. Kourembanas, and M. E. Lee 1994. Transforming growth factor-beta 1, but not dexamethasone, down-regulates nitric-oxide synthase mRNA after its induction by interleukin-1 beta in rat smooth muscle cells. J. Biol. Chem 269:14595-14600
26. Oshima, J., K. E. Steinmann, J. Campisi, and R. Schiegel. 1993. Modulation of cell growth, p34 cdc2 and cyclin A levels by SV-40 large T antigen. Oncogene. 8:2987-2993.
27. Meikrantz, W , S. Gisselbrecht, S. W. Tam, and R. Schlegel. 1994. Activation of cyclin A-dependent protein kinases during apoptosis. Proc. Nail. Acad. Sci. USA 91:3754-3758.
28. Yoshizumi, M., C-M Hsieh, F. Zhou, J.-C. Tsai, C. Patterson, M. A. Perrella, and M.-E. Lee. 1995. The ATF site mediates downregulation of the cyclin A gene during contact inhibition in vascular endothelial cells. Mol. Cell Biol 15:3266-3272.
29. Lee, M.-E., K. D. Bloch, J. A Clifford, and T Quertermous 1990. Functional analysis of the endothelin-1 gene promoter. Evidence for an endothelial cell-specific as-acting sequence. J. Biol. Chem. 265 10446-10450.
30. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular Cloning. A Laboratory Manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
31. Sherr, C. J. 1994. G1 phase progression: cycling on cue Cell. 79:551-555.
32. Henglein, B., X. Chenivesse, J. Wang, D. Eick, and C. Brechet 1994. Structure and cell cycle-regulated transcription of the human cyclin A gene. Proc. Nail Acad. Sci USA. 91:5490-5494.
33. Desdouets, C, G. Matesic, C. A. Molina, N. S. Foulkes. P. SassoncCorsi, C. Brecho, and J. Sobczak-Thepot 1995. Cell cycle regulation of cyclin A gene expression by the cyclin AMP-responsive transcription factors CREB and CREM. Mol. Cell. Biol. 15:3301-3309.
34. Cardoso, M. C. H. Leonhardt, and B Nadal-Ginard. 1993. Reversal of terminal differentiation and control of DNA replication: cyclin A and Cdk2 specifically localize at subnuclear sites of DNA replication. Cell 74:979-992.
35. Pines, J., and T. Hunter. 1991. Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport. J Cell Biol. 115:1-17.
36. Barrett, J. F., B. C. Lewis, A. T. Hoang, R. J. J. Alvarez, and C. V. Dang. 1995. Cyclin A links c-Myc to adhesion-independent cell proliferation. J. Biol. Chem 270:15923-15925.
37. Guadagno, T M., M. Ohtsubo, J. M. Roberts, and R. K Assoian. 1993. A link between cyclin A expression and adhesion-dependent cell cycle progression. Science (Wash. DC). 262:1572-1575.