-
1
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
Hanahan D., Weinberg R.A. Hallmarks of cancer: the next generation. Cell 2011, 144:646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
2
-
-
1842535882
-
Fusion genes and rearranged genes as a linear function of chromosome aberrations in cancer
-
Mitelman F., et al. Fusion genes and rearranged genes as a linear function of chromosome aberrations in cancer. Nat. Genet. 2004, 36:331-334.
-
(2004)
Nat. Genet.
, vol.36
, pp. 331-334
-
-
Mitelman, F.1
-
3
-
-
33947581390
-
The impact of translocations and gene fusions on cancer causation
-
Mitelman F., et al. The impact of translocations and gene fusions on cancer causation. Nat. Rev. Cancer 2007, 7:233-245.
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 233-245
-
-
Mitelman, F.1
-
4
-
-
39649117755
-
The impact of next-generation sequencing technology on genetics
-
Mardis E.R. The impact of next-generation sequencing technology on genetics. Trends Genet. 2008, 24:133-141.
-
(2008)
Trends Genet.
, vol.24
, pp. 133-141
-
-
Mardis, E.R.1
-
5
-
-
80054687429
-
Genome-wide approaches for cancer gene discovery
-
Lizardi P.M., et al. Genome-wide approaches for cancer gene discovery. Trends Biotechnol. 2011, 29:558-568.
-
(2011)
Trends Biotechnol.
, vol.29
, pp. 558-568
-
-
Lizardi, P.M.1
-
6
-
-
36248980204
-
Characterizing the cancer genome in lung adenocarcinoma
-
Weir B.A., et al. Characterizing the cancer genome in lung adenocarcinoma. Nature 2007, 450:893-898.
-
(2007)
Nature
, vol.450
, pp. 893-898
-
-
Weir, B.A.1
-
7
-
-
38949218379
-
Genomic imbalances in 5918 malignant epithelial tumors: an explorative meta-analysis of chromosomal CGH data
-
Baudis M., et al. Genomic imbalances in 5918 malignant epithelial tumors: an explorative meta-analysis of chromosomal CGH data. BMC Cancer 2007, 7:226.
-
(2007)
BMC Cancer
, vol.7
, pp. 226
-
-
Baudis, M.1
-
8
-
-
54049149961
-
Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma
-
Janoueix-Lerosey I., et al. Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma. Nature 2008, 455:967-970.
-
(2008)
Nature
, vol.455
, pp. 967-970
-
-
Janoueix-Lerosey, I.1
-
9
-
-
77249123407
-
Signatures of mutation and selection in the cancer genome
-
Bignell G.R., et al. Signatures of mutation and selection in the cancer genome. Nature 2010, 463:893-898.
-
(2010)
Nature
, vol.463
, pp. 893-898
-
-
Bignell, G.R.1
-
10
-
-
77249119762
-
The landscape of somatic copy-number alteration across human cancers
-
Beroukhim R., et al. The landscape of somatic copy-number alteration across human cancers. Nature 2010, 463:899-905.
-
(2010)
Nature
, vol.463
, pp. 899-905
-
-
Beroukhim, R.1
-
11
-
-
54549108740
-
Cancer Genome Atlas Research Network
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature
-
Cancer Genome Atlas Research Network (2008) Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455, 1061-1068.
-
(2008)
, vol.455
, pp. 1061-1068
-
-
-
12
-
-
77954255681
-
Integrative genomic profiling of human prostate cancer
-
Taylor B.S., et al. Integrative genomic profiling of human prostate cancer. Cancer Cell 2010, 18:11-22.
-
(2010)
Cancer Cell
, vol.18
, pp. 11-22
-
-
Taylor, B.S.1
-
13
-
-
79959838081
-
Cancer Genome Atlas Research Network
-
Integrated genomic analyses of ovarian carcinoma. Nature
-
Cancer Genome Atlas Research Network (2011) Integrated genomic analyses of ovarian carcinoma. Nature 474, 609-615.
-
(2011)
, vol.474
, pp. 609-615
-
-
-
14
-
-
33947101019
-
Patterns of somatic mutation in human cancer genomes
-
Greenman C., et al. Patterns of somatic mutation in human cancer genomes. Nature 2007, 446:153-158.
-
(2007)
Nature
, vol.446
, pp. 153-158
-
-
Greenman, C.1
-
15
-
-
54549094903
-
Somatic mutations affect key pathways in lung adenocarcinoma
-
Ding L., et al. Somatic mutations affect key pathways in lung adenocarcinoma. Nature 2008, 455:1069-1075.
-
(2008)
Nature
, vol.455
, pp. 1069-1075
-
-
Ding, L.1
-
16
-
-
77955660663
-
Diverse somatic mutation patterns and pathway alterations in human cancers
-
Kan Z., et al. Diverse somatic mutation patterns and pathway alterations in human cancers. Nature 2010, 466:869-873.
-
(2010)
Nature
, vol.466
, pp. 869-873
-
-
Kan, Z.1
-
17
-
-
52149123619
-
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
-
Jones S., et al. Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Science 2008, 321:1801-1806.
-
(2008)
Science
, vol.321
, pp. 1801-1806
-
-
Jones, S.1
-
18
-
-
36248962105
-
The genomic landscapes of human breast and colorectal cancers
-
Wood L.D., et al. The genomic landscapes of human breast and colorectal cancers. Science 2007, 318:1108-1113.
-
(2007)
Science
, vol.318
, pp. 1108-1113
-
-
Wood, L.D.1
-
19
-
-
44349191457
-
Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing
-
Campbell P.J., et al. Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing. Nat. Genet. 2008, 40:722-729.
-
(2008)
Nat. Genet.
, vol.40
, pp. 722-729
-
-
Campbell, P.J.1
-
20
-
-
72949119310
-
Complex landscapes of somatic rearrangement in human breast cancer genomes
-
Stephens P.J., et al. Complex landscapes of somatic rearrangement in human breast cancer genomes. Nature 2009, 462:1005-1010.
-
(2009)
Nature
, vol.462
, pp. 1005-1010
-
-
Stephens, P.J.1
-
21
-
-
74449085934
-
A small-cell lung cancer genome with complex signatures of tobacco exposure
-
Pleasance E.D., et al. A small-cell lung cancer genome with complex signatures of tobacco exposure. Nature 2010, 463:184-190.
-
(2010)
Nature
, vol.463
, pp. 184-190
-
-
Pleasance, E.D.1
-
22
-
-
74449093973
-
A comprehensive catalogue of somatic mutations from a human cancer genome
-
Pleasance E.D., et al. A comprehensive catalogue of somatic mutations from a human cancer genome. Nature 2010, 463:191-196.
-
(2010)
Nature
, vol.463
, pp. 191-196
-
-
Pleasance, E.D.1
-
23
-
-
77953006634
-
The mutation spectrum revealed by paired genome sequences from a lung cancer patient
-
Lee W., et al. The mutation spectrum revealed by paired genome sequences from a lung cancer patient. Nature 2010, 465:473-477.
-
(2010)
Nature
, vol.465
, pp. 473-477
-
-
Lee, W.1
-
24
-
-
77951139631
-
Genome remodelling in a basal-like breast cancer metastasis and xenograft
-
Ding L., et al. Genome remodelling in a basal-like breast cancer metastasis and xenograft. Nature 2010, 464:999-1005.
-
(2010)
Nature
, vol.464
, pp. 999-1005
-
-
Ding, L.1
-
25
-
-
78049380554
-
The patterns and dynamics of genomic instability in metastatic pancreatic cancer
-
Campbell P.J., et al. The patterns and dynamics of genomic instability in metastatic pancreatic cancer. Nature 2010, 467:1109-1113.
-
(2010)
Nature
, vol.467
, pp. 1109-1113
-
-
Campbell, P.J.1
-
26
-
-
78650959663
-
Massive genomic rearrangement acquired in a single catastrophic event during cancer development
-
Stephens P.J., et al. Massive genomic rearrangement acquired in a single catastrophic event during cancer development. Cell 2011, 144:27-40.
-
(2011)
Cell
, vol.144
, pp. 27-40
-
-
Stephens, P.J.1
-
27
-
-
79951497419
-
The genomic complexity of primary human prostate cancer
-
Berger M.F., et al. The genomic complexity of primary human prostate cancer. Nature 2011, 470:214-220.
-
(2011)
Nature
, vol.470
, pp. 214-220
-
-
Berger, M.F.1
-
28
-
-
79955555195
-
Comprehensive long-span paired-end-tag mapping reveals characteristic patterns of structural variations in epithelial cancer genomes
-
Hillmer A.M., et al. Comprehensive long-span paired-end-tag mapping reveals characteristic patterns of structural variations in epithelial cancer genomes. Genome Res. 2011, 21:665-675.
-
(2011)
Genome Res.
, vol.21
, pp. 665-675
-
-
Hillmer, A.M.1
-
29
-
-
85027927831
-
High-resolution characterization of a hepatocellular carcinoma genome
-
Totoki Y., et al. High-resolution characterization of a hepatocellular carcinoma genome. Nat. Genet. 2011, 43:464-469.
-
(2011)
Nat. Genet.
, vol.43
, pp. 464-469
-
-
Totoki, Y.1
-
30
-
-
79951494668
-
Initial genome sequencing and analysis of multiple myeloma
-
Chapman M.A., et al. Initial genome sequencing and analysis of multiple myeloma. Nature 2011, 471:467-472.
-
(2011)
Nature
, vol.471
, pp. 467-472
-
-
Chapman, M.A.1
-
31
-
-
79960036578
-
Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
-
Puente X.S., et al. Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia. Nature 2011, 475:101-105.
-
(2011)
Nature
, vol.475
, pp. 101-105
-
-
Puente, X.S.1
-
32
-
-
80053385552
-
Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion
-
Bass A.J., et al. Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion. Nat. Genet. 2011, 43:964-968.
-
(2011)
Nat. Genet.
, vol.43
, pp. 964-968
-
-
Bass, A.J.1
-
33
-
-
79955560249
-
Transcriptional consequences of genomic structural aberrations in breast cancer
-
Inaki K., et al. Transcriptional consequences of genomic structural aberrations in breast cancer. Genome Res. 2011, 21:676-687.
-
(2011)
Genome Res.
, vol.21
, pp. 676-687
-
-
Inaki, K.1
-
34
-
-
65249144557
-
Commonality but diversity in cancer gene fusions
-
Rabbitts T.H. Commonality but diversity in cancer gene fusions. Cell 2009, 137:391-395.
-
(2009)
Cell
, vol.137
, pp. 391-395
-
-
Rabbitts, T.H.1
-
35
-
-
33646674254
-
Chromosomal translocations in cancer and their relevance for therapy
-
Taki T., Taniwaki M. Chromosomal translocations in cancer and their relevance for therapy. Curr. Opin. Oncol. 2006, 18:62-68.
-
(2006)
Curr. Opin. Oncol.
, vol.18
, pp. 62-68
-
-
Taki, T.1
Taniwaki, M.2
-
36
-
-
34547638047
-
Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer
-
Soda M., et al. Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer. Nature 2007, 448:561-566.
-
(2007)
Nature
, vol.448
, pp. 561-566
-
-
Soda, M.1
-
37
-
-
36849065315
-
Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer
-
Rikova K., et al. Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. Cell 2007, 131:1190-1203.
-
(2007)
Cell
, vol.131
, pp. 1190-1203
-
-
Rikova, K.1
-
38
-
-
70349510460
-
Exon array profiling detects EML4-ALK fusion in breast, colorectal, and non-small cell lung cancers
-
Lin E., et al. Exon array profiling detects EML4-ALK fusion in breast, colorectal, and non-small cell lung cancers. Mol. Cancer Res. 2009, 7:1466-1476.
-
(2009)
Mol. Cancer Res.
, vol.7
, pp. 1466-1476
-
-
Lin, E.1
-
39
-
-
78049425319
-
Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer
-
Kwak E.L., et al. Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. N. Engl. J. Med. 2010, 363:1693-1703.
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 1693-1703
-
-
Kwak, E.L.1
-
41
-
-
19044391610
-
Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinoma
-
Tognon C., et al. Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinoma. Cancer Cell 2002, 2:367-376.
-
(2002)
Cancer Cell
, vol.2
, pp. 367-376
-
-
Tognon, C.1
-
42
-
-
36649021126
-
ETV6-NTRK3 fusion oncogene initiates breast cancer from committed mammary progenitors via activation of AP1 complex
-
Li Z., et al. ETV6-NTRK3 fusion oncogene initiates breast cancer from committed mammary progenitors via activation of AP1 complex. Cancer Cell 2007, 12:542-558.
-
(2007)
Cancer Cell
, vol.12
, pp. 542-558
-
-
Li, Z.1
-
43
-
-
77954526989
-
Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma
-
Palanisamy N., et al. Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma. Nat. Med. 2010, 16:793-798.
-
(2010)
Nat. Med.
, vol.16
, pp. 793-798
-
-
Palanisamy, N.1
-
44
-
-
27244452418
-
NUP98 fusion in human leukemia: dysregulation of the nuclear pore and homeodomain proteins
-
Nakamura T. NUP98 fusion in human leukemia: dysregulation of the nuclear pore and homeodomain proteins. Int. J. Hematol. 2005, 82:21-27.
-
(2005)
Int. J. Hematol.
, vol.82
, pp. 21-27
-
-
Nakamura, T.1
-
45
-
-
27344451557
-
Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer
-
Tomlins S.A., et al. Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science 2005, 310:644-648.
-
(2005)
Science
, vol.310
, pp. 644-648
-
-
Tomlins, S.A.1
-
46
-
-
34547642493
-
Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer
-
Tomlins S.A., et al. Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer. Nature 2007, 448:595-599.
-
(2007)
Nature
, vol.448
, pp. 595-599
-
-
Tomlins, S.A.1
-
47
-
-
39049170313
-
Characterization of TMPRSS2:ETV5 and SLC45A3:ETV5 gene fusions in prostate cancer
-
Helgeson B.E., et al. Characterization of TMPRSS2:ETV5 and SLC45A3:ETV5 gene fusions in prostate cancer. Cancer Res. 2008, 68:73-80.
-
(2008)
Cancer Res.
, vol.68
, pp. 73-80
-
-
Helgeson, B.E.1
-
48
-
-
39049150843
-
Role of the TMPRSS2-ERG gene fusion in prostate cancer
-
Tomlins S.A., et al. Role of the TMPRSS2-ERG gene fusion in prostate cancer. Neoplasia 2008, 10:177-188.
-
(2008)
Neoplasia
, vol.10
, pp. 177-188
-
-
Tomlins, S.A.1
-
49
-
-
70350109641
-
ETS gene fusions in prostate cancer
-
Clark J.P., Cooper C.S. ETS gene fusions in prostate cancer. Nat. Rev. Urol. 2009, 6:429-439.
-
(2009)
Nat. Rev. Urol.
, vol.6
, pp. 429-439
-
-
Clark, J.P.1
Cooper, C.S.2
-
50
-
-
6944252248
-
Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemia
-
Graux C., et al. Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemia. Nat. Genet. 2004, 36:1084-1089.
-
(2004)
Nat. Genet.
, vol.36
, pp. 1084-1089
-
-
Graux, C.1
-
51
-
-
33750087521
-
The MLL partial tandem duplication in acute myeloid leukaemia
-
Basecke J., et al. The MLL partial tandem duplication in acute myeloid leukaemia. Br. J. Haematol. 2006, 135:438-449.
-
(2006)
Br. J. Haematol.
, vol.135
, pp. 438-449
-
-
Basecke, J.1
-
52
-
-
67650351086
-
Structural and functional alterations of FLT3 in acute myeloid leukemia
-
Meshinchi S., Appelbaum F.R. Structural and functional alterations of FLT3 in acute myeloid leukemia. Clin. Cancer Res. 2009, 15:4263-4269.
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 4263-4269
-
-
Meshinchi, S.1
Appelbaum, F.R.2
-
53
-
-
84857996064
-
The role of tandem duplicator phenotype in tumour evolution in high-grade serous ovarian cancer
-
Ng C.K., et al. The role of tandem duplicator phenotype in tumour evolution in high-grade serous ovarian cancer. J. Pathol. 2012, 226:703-712.
-
(2012)
J. Pathol.
, vol.226
, pp. 703-712
-
-
Ng, C.K.1
-
54
-
-
79960693423
-
Chromothripsis identifies a rare and aggressive entity among newly diagnosed multiple myeloma patients
-
Magrangeas F., et al. Chromothripsis identifies a rare and aggressive entity among newly diagnosed multiple myeloma patients. Blood 2011, 118:675-678.
-
(2011)
Blood
, vol.118
, pp. 675-678
-
-
Magrangeas, F.1
-
55
-
-
80054698731
-
Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer
-
Kloosterman W.P., et al. Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer. Genome Biol. 2011, 12:R103.
-
(2011)
Genome Biol.
, vol.12
-
-
Kloosterman, W.P.1
-
56
-
-
84856424908
-
DNA breaks and chromosome pulverization from errors in mitosis
-
Crasta K., et al. DNA breaks and chromosome pulverization from errors in mitosis. Nature 2012, 482:53-58.
-
(2012)
Nature
, vol.482
, pp. 53-58
-
-
Crasta, K.1
-
57
-
-
67651098662
-
Mechanisms of change in gene copy number
-
Hastings P.J., et al. Mechanisms of change in gene copy number. Nat. Rev. Genet. 2009, 10:551-564.
-
(2009)
Nat. Rev. Genet.
, vol.10
, pp. 551-564
-
-
Hastings, P.J.1
-
58
-
-
77953229115
-
The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway
-
Lieber M.R. The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway. Annu. Rev. Biochem. 2010, 79:181-211.
-
(2010)
Annu. Rev. Biochem.
, vol.79
, pp. 181-211
-
-
Lieber, M.R.1
-
59
-
-
77649165394
-
Maintaining genome stability at the replication fork
-
Branzei D., Foiani M. Maintaining genome stability at the replication fork. Nat. Rev. Mol. Cell Biol. 2010, 11:208-219.
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 208-219
-
-
Branzei, D.1
Foiani, M.2
-
60
-
-
70849135782
-
Induced chromosomal proximity and gene fusions in prostate cancer
-
Mani R.S., et al. Induced chromosomal proximity and gene fusions in prostate cancer. Science 2009, 326:1230.
-
(2009)
Science
, vol.326
, pp. 1230
-
-
Mani, R.S.1
-
61
-
-
71249101060
-
Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specific translocations in cancer
-
Lin C., et al. Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specific translocations in cancer. Cell 2009, 139:1069-1083.
-
(2009)
Cell
, vol.139
, pp. 1069-1083
-
-
Lin, C.1
-
62
-
-
77955069195
-
Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements
-
Haffner M.C., et al. Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements. Nat. Genet. 2010, 42:668-675.
-
(2010)
Nat. Genet.
, vol.42
, pp. 668-675
-
-
Haffner, M.C.1
-
63
-
-
39449096135
-
Genome instability: a mechanistic view of its causes and consequences
-
Aguilera A., Gómez-González B. Genome instability: a mechanistic view of its causes and consequences. Nat. Rev. Genet. 2008, 9:204-217.
-
(2008)
Nat. Rev. Genet.
, vol.9
, pp. 204-217
-
-
Aguilera, A.1
Gómez-González, B.2
-
64
-
-
80053558376
-
Genome-wide translocation sequencing reveals mechanisms of chromosome breaks and rearrangements in B cells
-
Chiarle R., et al. Genome-wide translocation sequencing reveals mechanisms of chromosome breaks and rearrangements in B cells. Cell 2011, 147:107-119.
-
(2011)
Cell
, vol.147
, pp. 107-119
-
-
Chiarle, R.1
-
65
-
-
80053502216
-
Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes
-
Klein I.A., et al. Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes. Cell 2011, 147:95-106.
-
(2011)
Cell
, vol.147
, pp. 95-106
-
-
Klein, I.A.1
-
66
-
-
0038054340
-
Spatial proximity of translocation-prone gene loci in human lymphomas
-
Roix J.J., et al. Spatial proximity of translocation-prone gene loci in human lymphomas. Nat. Genet. 2003, 34:287-291.
-
(2003)
Nat. Genet.
, vol.34
, pp. 287-291
-
-
Roix, J.J.1
-
67
-
-
34548210885
-
Myc dynamically and preferentially relocates to a transcription factory occupied by Igh
-
Osborne C.S., et al. Myc dynamically and preferentially relocates to a transcription factory occupied by Igh. PLoS Biol. 2007, 5:e192.
-
(2007)
PLoS Biol.
, vol.5
-
-
Osborne, C.S.1
-
68
-
-
70449103609
-
An oestrogen-receptor-alpha-bound human chromatin interactome
-
Fullwood M.J., et al. An oestrogen-receptor-alpha-bound human chromatin interactome. Nature 2009, 462:58-64.
-
(2009)
Nature
, vol.462
, pp. 58-64
-
-
Fullwood, M.J.1
-
69
-
-
69449108384
-
Genome-organizing factors Top2 and Hmo1 prevent chromosome fragility at sites of S phase transcription
-
Bermejo R., et al. Genome-organizing factors Top2 and Hmo1 prevent chromosome fragility at sites of S phase transcription. Cell 2009, 138:870-884.
-
(2009)
Cell
, vol.138
, pp. 870-884
-
-
Bermejo, R.1
-
70
-
-
67549119096
-
CTCF: master weaver of the genome
-
Phillips J.E., Corces V.G. CTCF: master weaver of the genome. Cell 2009, 137:1194-1211.
-
(2009)
Cell
, vol.137
, pp. 1194-1211
-
-
Phillips, J.E.1
Corces, V.G.2
-
71
-
-
79959699992
-
CTCF-mediated functional chromatin interactome in pluripotent cells
-
Handoko L., et al. CTCF-mediated functional chromatin interactome in pluripotent cells. Nat. Genet. 2011, 43:630-638.
-
(2011)
Nat. Genet.
, vol.43
, pp. 630-638
-
-
Handoko, L.1
-
72
-
-
80053539409
-
Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity
-
Song L., et al. Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity. Genome Res. 2011, 21:1757-1767.
-
(2011)
Genome Res.
, vol.21
, pp. 1757-1767
-
-
Song, L.1
-
73
-
-
77649235074
-
Programming DNA replication origins and chromosome organization
-
Cayrou C., et al. Programming DNA replication origins and chromosome organization. Chromosome Res. 2010, 18:137-145.
-
(2010)
Chromosome Res.
, vol.18
, pp. 137-145
-
-
Cayrou, C.1
-
74
-
-
78650186593
-
Cohesin organizes chromatin loops at DNA replication factories
-
Guillou E., et al. Cohesin organizes chromatin loops at DNA replication factories. Genes Dev. 2010, 24:2812-2822.
-
(2010)
Genes Dev.
, vol.24
, pp. 2812-2822
-
-
Guillou, E.1
-
75
-
-
66149138883
-
Transcription initiation activity sets replication origin efficiency in mammalian cells
-
Sequeira-Mendes J., et al. Transcription initiation activity sets replication origin efficiency in mammalian cells. PLoS Genet. 2009, 5:e1000446.
-
(2009)
PLoS Genet.
, vol.5
-
-
Sequeira-Mendes, J.1
-
76
-
-
79955940233
-
Preferential localization of human origins of DNA replication at the 5'-ends of expressed genes and at evolutionarily conserved DNA sequences
-
Valenzuela M.S., et al. Preferential localization of human origins of DNA replication at the 5'-ends of expressed genes and at evolutionarily conserved DNA sequences. PLoS ONE 2011, 6:e17308.
-
(2011)
PLoS ONE
, vol.6
-
-
Valenzuela, M.S.1
-
77
-
-
52549115459
-
Replication licensing and cancer: a fatal entanglement?
-
Blow J.J., Gillespie P.J. Replication licensing and cancer: a fatal entanglement?. Nat. Rev. Cancer 2008, 8:799-806.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 799-806
-
-
Blow, J.J.1
Gillespie, P.J.2
-
78
-
-
36749103631
-
Mechanisms to control rereplication and implications for cancer
-
Hook S.S., et al. Mechanisms to control rereplication and implications for cancer. Curr. Opin. Cell Biol. 2007, 19:663-671.
-
(2007)
Curr. Opin. Cell Biol.
, vol.19
, pp. 663-671
-
-
Hook, S.S.1
-
79
-
-
77955870154
-
Loss of DNA replication control is a potent inducer of gene amplification
-
Green B.M., et al. Loss of DNA replication control is a potent inducer of gene amplification. Science 2010, 329:943-946.
-
(2010)
Science
, vol.329
, pp. 943-946
-
-
Green, B.M.1
-
80
-
-
66049138940
-
Breakpoint regions and homologous synteny blocks in chromosomes have different evolutionary histories
-
Larkin D.M., et al. Breakpoint regions and homologous synteny blocks in chromosomes have different evolutionary histories. Genome Res. 2009, 19:770-777.
-
(2009)
Genome Res.
, vol.19
, pp. 770-777
-
-
Larkin, D.M.1
-
81
-
-
0032169516
-
The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2
-
Stott F.J., et al. The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2. EMBO J. 1998, 17:5001-5014.
-
(1998)
EMBO J.
, vol.17
, pp. 5001-5014
-
-
Stott, F.J.1
-
82
-
-
0032504783
-
P14ARF links the tumour suppressors RB and p53
-
Bates S., et al. p14ARF links the tumour suppressors RB and p53. Nature 1998, 395:124-125.
-
(1998)
Nature
, vol.395
, pp. 124-125
-
-
Bates, S.1
-
83
-
-
79959652880
-
Large-scale analysis of chromosomal aberrations in cancer karyotypes reveals two distinct paths to aneuploidy
-
Ozery-Flato M., et al. Large-scale analysis of chromosomal aberrations in cancer karyotypes reveals two distinct paths to aneuploidy. Genome Biol. 2011, 12:R61.
-
(2011)
Genome Biol.
, vol.12
-
-
Ozery-Flato, M.1
-
84
-
-
78049398107
-
Distant metastasis occurs late during the genetic evolution of pancreatic cancer
-
Yachida S., et al. Distant metastasis occurs late during the genetic evolution of pancreatic cancer. Nature 2010, 467:1114-1117.
-
(2010)
Nature
, vol.467
, pp. 1114-1117
-
-
Yachida, S.1
-
85
-
-
79953766940
-
Tumour evolution inferred by single-cell sequencing
-
Navin N., et al. Tumour evolution inferred by single-cell sequencing. Nature 2011, 472:90-94.
-
(2011)
Nature
, vol.472
, pp. 90-94
-
-
Navin, N.1
|