-
1
-
-
0025899041
-
Amyloid deposition as the central event in the aetiology of Alzheimer's disease
-
Hardy J, Allsop D. Amyloid deposition as the central event in the aetiology of Alzheimer's disease. Trends Pharmacol Sci 1991; 12: 383-388.
-
(1991)
Trends Pharmacol Sci
, vol.12
, pp. 383-388
-
-
Hardy, J.1
Allsop, D.2
-
2
-
-
77956217986
-
Parkinson's disease: A model dilemma
-
Beal MF. Parkinson's disease: a model dilemma. Nature 2010; 466: S8-S10.
-
(2010)
Nature
, vol.466
-
-
Beal, M.F.1
-
3
-
-
0027401203
-
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
Rosen DR, Siddique T, Patterson D, Figlewicz DA, Sapp P, Hentati A, et al. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 1993; 362: 59-62.
-
(1993)
Nature
, vol.362
, pp. 59-62
-
-
Rosen, D.R.1
Siddique, T.2
Patterson, D.3
Figlewicz, D.A.4
Sapp, P.5
Hentati, A.6
-
4
-
-
3943102116
-
Unraveling the mechanisms involved in motor neuron degeneration in ALS
-
Bruijn LI, Miller TM, Cleveland DW. Unraveling the mechanisms involved in motor neuron degeneration in ALS. Annu Rev Neurosci 2004; 27: 723-749.
-
(2004)
Annu Rev Neurosci
, vol.27
, pp. 723-749
-
-
Bruijn, L.I.1
Miller, T.M.2
Cleveland, D.W.3
-
5
-
-
0242668337
-
Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
-
Kayed R, Head E, Thompson JL, McIntire TM, Milton SC, Cotman CW, Glabe CG. Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science 2003; 300: 486-489.
-
(2003)
Science
, vol.300
, pp. 486-489
-
-
Kayed, R.1
Head, E.2
Thompson, J.L.3
McIntire, T.M.4
Milton, S.C.5
Cotman, C.W.6
Glabe, C.G.7
-
6
-
-
68049131389
-
A ®oligomers and fi brillar aggregates induce diff erent apoptotic pathways in LAN5 neuroblastoma cell cultures
-
Picone P, Carrotta R, Montana G, Nobile MR, San Biagio PL, Di Carlo M. A ®oligomers and fi brillar aggregates induce diff erent apoptotic pathways in LAN5 neuroblastoma cell cultures. Biophys J 2009; 96: 1133-1145.
-
(2009)
Biophys J
, vol.96
, pp. 1133-1145
-
-
Picone, P.1
Carrotta, R.2
Montana, G.3
Nobile, M.R.4
San Biagio, P.L.5
Di Carlo, M.6
-
7
-
-
0034641936
-
Apoptosis in the nervous system
-
Yuan J, Yanker B. Apoptosis in the nervous system. Nature 2000; 407: 802-809.
-
(2000)
Nature
, vol.407
, pp. 802-809
-
-
Yuan, J.1
Yanker, B.2
-
8
-
-
79959216154
-
Membrane incorporation, channel formation and disruption of calcium homeostasis by Alzheimer's b-amyloid protein
-
Article ID 304583 (17 pages)
-
Kawahara M, Ohtsuka I, Yokoyama S, Kato-Negishi M, Sadakane Y. Membrane incorporation, channel formation and disruption of calcium homeostasis by Alzheimer's b-amyloid protein. Int J Alz Dis 2011; Article ID 304583 (17 pages).
-
(2011)
Int J Alz Dis
-
-
Kawahara, M.1
Ohtsuka, I.2
Yokoyama, S.3
Kato-Negishi, M.4
Sadakane, Y.5
-
9
-
-
1842519391
-
Alzheimer's amyloid beta-peptide (1-42) involvement of methionine residue 35 in the oxidative stress and neurotoxic properties of this peptide
-
Butterfield DA, Bush AI. Alzheimer's amyloid beta-peptide (1-42): involvement of methionine residue 35 in the oxidative stress and neurotoxic properties of this peptide. Neurobiol Aging 2004; 25: 563-568.
-
(2004)
Neurobiol Aging
, vol.25
, pp. 563-568
-
-
Butterfield, D.A.1
Bush, A.I.2
-
10
-
-
0035880007
-
Brain protein oxidation in agerelated neurodegenerative disorders that are associated with aggregated proteins
-
Butterfield DA, Kanski J. Brain protein oxidation in agerelated neurodegenerative disorders that are associated with aggregated proteins. Mech Ageing Dev 2002; 122: 945-962.
-
(2002)
Mech Ageing Dev
, vol.122
, pp. 945-962
-
-
Butterfield, D.A.1
Kanski, J.2
-
11
-
-
0036591863
-
Substitution of isoleucine-31 by helical-breaking proline abolishes oxidative stress and neurotoxic properties of Alzheimer's amyloid h-peptide (1-42)
-
Kanski J, Aksenova M, Schoneich C, Butterfield DA. Substitution of isoleucine-31 by helical-breaking proline abolishes oxidative stress and neurotoxic properties of Alzheimer's amyloid h-peptide (1-42). Free Radic Biol Med 2002; 32: 1205-1211.
-
(2002)
Free Radic Biol Med
, vol.32
, pp. 1205-1211
-
-
Kanski, J.1
Aksenova, M.2
Schoneich, C.3
Butterfield, D.A.4
-
12
-
-
18344414746
-
The A peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction
-
Huang X, Atwood CS, Hartshorn MA, Multhaup G, Goldstein LE, Scarpa RC, et al. The A peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction. Biochemistry 1999; 38: 7609-7616.
-
(1999)
Biochemistry
, vol.38
, pp. 7609-7616
-
-
Huang, X.1
Atwood, C.S.2
Hartshorn, M.A.3
Multhaup, G.4
Goldstein, L.E.5
Scarpa, R.C.6
-
13
-
-
59149084113
-
Metal-dependent generation of reactive oxygen species from amyloid proteins implicated in neurodegenerative disease
-
Allsop D, Mayes J, Moore S, Masad A, Tabner BJ. Metal-dependent generation of reactive oxygen species from amyloid proteins implicated in neurodegenerative disease. Biochem Soc Trans 2008; 36: 1293-1298.
-
(2008)
Biochem Soc Trans
, vol.36
, pp. 1293-1298
-
-
Allsop, D.1
Mayes, J.2
Moore, S.3
Masad, A.4
Tabner, B.J.5
-
14
-
-
67649687039
-
An integrative view of the role of oxidative stress, mitochondria and insulin in Alzheimer's disease
-
Moreira PI, Duarte AI, Santos MS, Rego MS, Oliveira CR. An integrative view of the role of oxidative stress, mitochondria and insulin in Alzheimer's disease. J Alzheimers Dis 2009; 17: 741-761.
-
(2009)
J Alzheimers Dis
, vol.17
, pp. 741-761
-
-
Moreira, P.I.1
Duarte, A.I.2
Santos, M.S.3
Rego, M.S.4
Oliveira, C.R.5
-
15
-
-
81555225182
-
Oxidative stress in neurodegeneration
-
Article ID 572634
-
Shukla V, Mishra SK, Pant HC. Oxidative stress in neurodegeneration. Adv Pharm Sci 2011; Article ID 572634, 13 pages.
-
(2011)
Adv Pharm Sci
, pp. 13
-
-
Shukla, V.1
Mishra, S.K.2
Pant, H.C.3
-
16
-
-
80052800916
-
Insulin-activated Akt rescues A ®oxidative stress-induced cell death by orchestrating molecular traffi cking
-
Picone P, Giacomazza D, Vetri V, Carrotta R, Militello V, San Biagio PL, Di Carlo M. Insulin-activated Akt rescues A ®oxidative stress-induced cell death by orchestrating molecular traffi cking. Aging Cell 2011; 10: 832-843
-
(2011)
Aging Cell
, vol.10
, pp. 832-843
-
-
Picone, P.1
Giacomazza, D.2
Vetri, V.3
Carrotta, R.4
Militello, V.5
San Biagio, P.L.6
Di Carlo, M.7
-
17
-
-
0031939204
-
Protein nitration in Parkinson disease
-
Good PF, Hsu A, Werner P, Perl DP, Olanow CW. Protein nitration in Parkinson disease. J Neuropathol Exp Neurol 1998; 56: 338-342.
-
(1998)
J Neuropathol Exp Neurol
, vol.56
, pp. 338-342
-
-
Good, P.F.1
Hsu, A.2
Werner, P.3
Perl, D.P.4
Olanow, C.W.5
-
18
-
-
0024490143
-
Superoxide dismutase activity in Alzheimer's disease: Possible mechanisMFor paired helical filament formation
-
Zemlan FP, Thienhaus OJ, Bosmann HB. Superoxide dismutase activity in Alzheimer's disease: possible mechanisMFor paired helical filament formation. Brain Res 1989; 476: 160-162.
-
(1989)
Brain Res
, vol.476
, pp. 160-162
-
-
Zemlan, F.P.1
Thienhaus, O.J.2
Bosmann, H.B.3
-
19
-
-
0026823074
-
Immunohistocheical evidence of oxidative stress in Alheimer's disease
-
Pappolla MA, Omar RA, Kim KS, Robakis NK. Immunohistocheical evidence of oxidative stress in Alheimer's disease. Am J Pathol 1992; 140: 621-628.
-
(1992)
Am J Pathol
, vol.140
, pp. 621-628
-
-
Pappolla, M.A.1
Omar, R.A.2
Kim, K.S.3
Robakis, N.K.4
-
20
-
-
0032823578
-
Decrease in peptide methionine sulfoxide reductase in Alzheimer's disease brain
-
Gabbita SP, Aksenov MY, Lovell MA, Markesbery WR. Decrease in peptide methionine sulfoxide reductase in Alzheimer's disease brain. J Neurochem 1999; 73: 1660-1666.
-
(1999)
J Neurochem
, vol.73
, pp. 1660-1666
-
-
Gabbita, S.P.1
Aksenov, M.Y.2
Lovell, M.A.3
Markesbery, W.R.4
-
21
-
-
0032797262
-
Nitric oxide synthases: Targets for therapeutic strategies in neurological diseases
-
Chabrier PE, Demerle-Pallardy C, Auguet M. Nitric oxide synthases: targets for therapeutic strategies in neurological diseases. Cell Mol Life Sci 1999; 55: 1029-1035.
-
(1999)
Cell Mol Life Sci
, vol.55
, pp. 1029-1035
-
-
Chabrier, P.E.1
Demerle-Pallardy, C.2
Auguet, M.3
-
22
-
-
0033899208
-
Glutathione, oxidative stress and neurodegeneration
-
Schulz JB, Lindenau J, Seyfried J, Dichgans J. Glutathione, oxidative stress and neurodegeneration. Eur J Biochem 2000; 267: 4904-4911.
-
(2000)
Eur J Biochem
, vol.267
, pp. 4904-4911
-
-
Schulz, J.B.1
Lindenau, J.2
Seyfried, J.3
Dichgans, J.4
-
23
-
-
0032749848
-
Mitochondrial physiology and pathology; Concepts of programmed death of organelles, cells and organisms
-
Skulachev VP. Mitochondrial physiology and pathology; concepts of programmed death of organelles, cells and organisms. Mol Aspects Med 1999; 20: 139-184.
-
(1999)
Mol Aspects Med
, vol.20
, pp. 139-184
-
-
Skulachev, V.P.1
-
24
-
-
0027686249
-
Oxidative stress, glutamate, and neurodegenerative disorders
-
Coyle JT, Puttfarcken P. Oxidative stress, glutamate, and neurodegenerative disorders. Science 1993;262: 689-695.
-
(1993)
Science
, vol.262
, pp. 689-695
-
-
Coyle, J.T.1
Puttfarcken, P.2
-
25
-
-
0034976070
-
Age related changes in the concentrations of major and trace elements in the brain of rats and mice
-
Takahashi S, Takahashi I, Sato H, Kubota Y, Yoshida S, Muramatsu Y. Age related changes in the concentrations of major and trace elements in the brain of rats and mice. Biol Trace Elem Res 2001; 80: 145-158.
-
(2001)
Biol Trace Elem Res
, vol.80
, pp. 145-158
-
-
Takahashi, S.1
Takahashi, I.2
Sato, H.3
Kubota, Y.4
Yoshida, S.5
Muramatsu, Y.6
-
26
-
-
0024541837
-
Mitochondrial DNA mutations as an important contributor to ageing and degenerative disease
-
Linnane AW, Marzuki S, Ozawa T, Tanaka M. Mitochondrial DNA mutations as an important contributor to ageing and degenerative disease. Lancet 1989; 333: 642-645.
-
(1989)
Lancet
, vol.333
, pp. 642-645
-
-
Linnane, A.W.1
Marzuki, S.2
Ozawa, T.3
Tanaka, M.4
-
27
-
-
0026775958
-
Free radical theory of aging
-
Harman D. Free radical theory of aging. Mutat Res 1992; 275: 257-266.
-
(1992)
Mutat Res
, vol.275
, pp. 257-266
-
-
Harman, D.1
-
28
-
-
0034565044
-
The biochemistry of aging
-
Knight JA. The biochemistry of aging. Adv Clin Chem 2000; 35: 1-62.
-
(2000)
Adv Clin Chem
, vol.35
, pp. 1-62
-
-
Knight, J.A.1
-
29
-
-
0027365312
-
Relationship between mitochondrial superoxide and hydrogen peroxide production and longevity of mammalian species
-
Ku HH, Brunk UT, Sohal RS. Relationship between mitochondrial superoxide and hydrogen peroxide production and longevity of mammalian species. Free Radic Biol Med 1993; 15: 621-627.
-
(1993)
Free Radic Biol Med
, vol.15
, pp. 621-627
-
-
Ku, H.H.1
Brunk, U.T.2
Sohal, R.S.3
-
30
-
-
33744998700
-
Temperature-dependent trade-off s between longevity and fertility in the Drosophila mutant, Methuselah
-
Mockett RJ, Sohal RJ, Sohal RS. Temperature-dependent trade-off s between longevity and fertility in the Drosophila mutant, Methuselah. Exp Gerontol 2006; 41: 566-573.
-
(2006)
Exp Gerontol
, vol.41
, pp. 566-573
-
-
Mockett, R.J.1
Sohal, R.J.2
Sohal, R.S.3
-
31
-
-
79955425933
-
Age-related changes in skeletal muscle reactive oxygen species generation and adaptive responses to reactive oxygen species
-
Jackson MJ, McArdle A. Age-related changes in skeletal muscle reactive oxygen species generation and adaptive responses to reactive oxygen species. J Physiol 2011; 589: 2139-2145.
-
(2011)
J Physiol
, vol.589
, pp. 2139-2145
-
-
Jackson, M.J.1
McArdle, A.2
-
32
-
-
0025614206
-
Oxidative stress as a causal factor in diff erentiation and aging: A unifying hypothesis
-
Sohal RS, Allen RG. Oxidative stress as a causal factor in diff erentiation and aging: a unifying hypothesis. Exp Gerontol 1990; 25: 499-522.
-
(1990)
Exp Gerontol
, vol.25
, pp. 499-522
-
-
Sohal, R.S.1
Allen, R.G.2
-
33
-
-
50249094970
-
The mitochondrial free radical theory of ageing-where do we stand
-
Gruber J, Schaff er S, Halliwell B. The mitochondrial free radical theory of ageing-where do we stand? Front Biosci 2008; 13: 6554-6579.
-
(2008)
Front Biosci
, vol.13
, pp. 6554-6579
-
-
Gruber, J.1
Schaff Er, S.2
Halliwell, B.3
-
35
-
-
0026023219
-
Hydrogen peroxide release by mitochondria increases during aging
-
Sohal RS, Sohal BH. Hydrogen peroxide release by mitochondria increases during aging. Mech Ageing Dev 1991; 57: 187-202.
-
(1991)
Mech Ageing Dev
, vol.57
, pp. 187-202
-
-
Sohal, R.S.1
Sohal, B.H.2
-
36
-
-
0028342438
-
Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse
-
Sohal RS, Ku HH, Agarwal S, Forster MJ, Lal H. Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse. Mech Ageing Dev 1994; 74: 121-133.
-
(1994)
Mech Ageing Dev
, vol.74
, pp. 121-133
-
-
Sohal, R.S.1
Ku, H.H.2
Agarwal, S.3
Forster, M.J.4
Lal, H.5
-
37
-
-
0031916984
-
The free radical theory of aging matures
-
Beckman KB, Ames BN. The free radical theory of aging matures. Physiol Rev 1998; 78: 547-581.
-
(1998)
Physiol Rev
, vol.78
, pp. 547-581
-
-
Beckman, K.B.1
Ames, B.N.2
-
38
-
-
0023214340
-
Effect of ambient temperature on free radical generation, antioxidant defenses and life span in the adult housefl y, Musca domestica
-
Farmer KJ, Sohal RS. Effect of ambient temperature on free radical generation, antioxidant defenses and life span in the adult housefl y, Musca domestica. Exp Gerontol 1987; 22: 59-65.
-
(1987)
Exp Gerontol
, vol.22
, pp. 59-65
-
-
Farmer, K.J.1
Sohal, R.S.2
-
39
-
-
0025309791
-
Mitochondrial mutations may increase oxidative stress: Implications for carcinogenesis and aging
-
Bandy B, Davison AJ. Mitochondrial mutations may increase oxidative stress: Implications for carcinogenesis and aging? Free Radic Biol Med 1990; 8: 523-539.
-
(1990)
Free Radic Biol Med
, vol.8
, pp. 523-539
-
-
Bandy, B.1
Davison, A.J.2
-
40
-
-
20144388830
-
ABAD enhances Abeta-induced cell stress via mitochondrial dysfunction
-
Takuma K, Yao J, Huang J, Xu H, Chen X, Luddy J, et al. ABAD enhances Abeta-induced cell stress via mitochondrial dysfunction. FASEB J 2005; 19: 597-598.
-
(2005)
FASEB J
, vol.19
, pp. 597-598
-
-
Takuma, K.1
Yao, J.2
Huang, J.3
Xu, H.4
Chen, X.5
Luddy, J.6
-
41
-
-
28744449206
-
Mitochondrial Abeta: A potential focal point for neuronal metabolic dysfunction in Alzheimer's disease
-
Caspersen C, Wang N, Yao J, Sosunov A, Chen X, Lustbader JW, et al. Mitochondrial Abeta: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease. FASEB J 2005; 19: 2040-2041.
-
(2005)
FASEB J
, vol.19
, pp. 2040-2041
-
-
Caspersen, C.1
Wang, N.2
Yao, J.3
Sosunov, A.4
Chen, X.5
Lustbader, J.W.6
-
42
-
-
33646152108
-
Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: Implications for free radical generation and oxidative damage in disease progression
-
Manczak M, Anekonda TS, Henson E, Park BS, Quinn J, Reddy PH. Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression. Hum Mol Genet 2006; 15: 1437-1449.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 1437-1449
-
-
Manczak, M.1
Anekonda, T.S.2
Henson, E.3
Park, B.S.4
Quinn, J.5
Reddy, P.H.6
-
43
-
-
11144353586
-
ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease
-
Lustbader JW, Cirilli M, Lin C, Xu HW, Takuma K, Wang N, et al. ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease. Science 2004; 304: 448-452.
-
(2004)
Science
, vol.304
, pp. 448-452
-
-
Lustbader, J.W.1
Cirilli, M.2
Lin, C.3
Xu, H.W.4
Takuma, K.5
Wang, N.6
-
44
-
-
33750683018
-
Alzheimer's APP mangles mitochondria
-
Lin MT, Beal MF. Alzheimer's APP mangles mitochondria. Nat Med 2006; 12: 1241-1243.
-
(2006)
Nat Med
, vol.12
, pp. 1241-1243
-
-
Lin, M.T.1
Beal, M.F.2
-
45
-
-
68949158352
-
The neurodegenerative mitochondriopathies
-
Swerdlow RH. The neurodegenerative mitochondriopathies. J Alzheimers Dis 2009; 17: 737-751.
-
(2009)
J Alzheimers Dis
, vol.17
, pp. 737-751
-
-
Swerdlow, R.H.1
-
46
-
-
33748283747
-
Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction
-
Devi L, Prabhu BM, Galati DF, Avadhani NG, Anandatheerthavarada HK. Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction. J Neurosci 2006; 26: 9057-9068.
-
(2006)
J Neurosci
, vol.26
, pp. 9057-9068
-
-
Devi, L.1
Prabhu, B.M.2
Galati, D.F.3
Avadhani, N.G.4
Anandatheerthavarada, H.K.5
-
47
-
-
51349110166
-
The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae
-
Hansson Petersen CA, Alikhani N, Behbahani H, Wiehager B, Pavlov PF, Alafuzoff I, et al. The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae. Proc Natl Acad Sci USA 2008; 105: 13145-13150
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 13145-13150
-
-
Hansson Petersen, C.A.1
Alikhani, N.2
Behbahani, H.3
Wiehager, B.4
Pavlov, P.F.5
Alafuzoff, I.6
-
48
-
-
53549129483
-
Cyclophilin D defi ciency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease
-
Du H, Guo L, Fang F, Chen D, Sosunov AA, McKhann GM, et al. Cyclophilin D defi ciency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease. Nat Med 2008; 14: 1097-1105.
-
(2008)
Nat Med
, vol.14
, pp. 1097-1105
-
-
Du, H.1
Guo, L.2
Fang, F.3
Chen, D.4
Sosunov, A.A.5
McKhann, G.M.6
-
49
-
-
0035341254
-
Mitochondrial abnormalities in Alzheimer's disease
-
Hirai K, Aliev G, Nunomura A, Fujioka H, Russell RL, Atwood CS, et al. Mitochondrial abnormalities in Alzheimer's disease. J Neurosci 2001; 21: 3017-3023.
-
(2001)
J Neurosci
, vol.21
, pp. 3017-3023
-
-
Hirai, K.1
Aliev, G.2
Nunomura, A.3
Fujioka, H.4
Russell, R.L.5
Atwood, C.S.6
-
50
-
-
19944433571
-
Copper-dependent inhibition of human cytochromec oxidase by a dimeric conformer of amyloid-beta1-42
-
Crouch PJ, Blake R, Duce JA, Ciccotosto GD, Li QX, Barnham KJ, et al. Copper-dependent inhibition of human cytochromec oxidase by a dimeric conformer of amyloid-beta1-42. J Neurosci 2005; 25: 672-679.
-
(2005)
J Neurosci
, vol.25
, pp. 672-679
-
-
Crouch, P.J.1
Blake, R.2
Duce, J.A.3
Ciccotosto, G.D.4
Li, Q.X.5
Barnham, K.J.6
-
51
-
-
73949088883
-
RAGE-mediated signaling contributes to intraneuronal transport of amyloid-beta and neuronal dysfunction
-
Takuma K, Fang F, Zhang W, Yan S, Fukuzaki E, Du H. RAGE-mediated signaling contributes to intraneuronal transport of amyloid-beta and neuronal dysfunction. Proc Natl Acad Sci USA 2009; 106: 20021-20026.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 20021-20026
-
-
Takuma, K.1
Fang, F.2
Zhang, W.3
Yan, S.4
Fukuzaki, E.5
Du, H.6
-
52
-
-
0024237306
-
Brefeldin A causes disassembly of the Golgi complex and accumulation of secretory proteins in the endoplasmic reticulum
-
Fujiwara T, Oda K, Yokota S, Takatsuki A, Ikehara Y. Brefeldin A causes disassembly of the Golgi complex and accumulation of secretory proteins in the endoplasmic reticulum. J Biol Chem 1988; 263: 18545-18552.
-
(1988)
J Biol Chem
, vol.263
, pp. 18545-18552
-
-
Fujiwara, T.1
Oda, K.2
Yokota, S.3
Takatsuki, A.4
Ikehara, Y.5
-
53
-
-
79952901937
-
Cyclophilin D defi ciency improves mitochondrial function and learning/memory in aging Alzheimer disease mouse model
-
Du H, Guo L, Zhang H, Rydzewska M, Yan Y. Cyclophilin D defi ciency improves mitochondrial function and learning/memory in aging Alzheimer disease mouse model. Neurobiol Aging 2011; 32: 398-406.
-
(2011)
Neurobiol Aging
, vol.32
, pp. 398-406
-
-
Du, H.1
Guo, L.2
Zhang, H.3
Rydzewska, M.4
Yan, Y.5
-
54
-
-
3042736860
-
Gene expression profi les of transcripts in amyloid precursor protein transgenic mice: Up-regulation of mitochondrial metabolism and apoptotic genes is an early cellular change in Alzheimer's disease
-
Reddy PH, McWeeney S, Park BS, Manczak M, Gutala RV, Partovi D, et al. Gene expression profi les of transcripts in amyloid precursor protein transgenic mice: up-regulation of mitochondrial metabolism and apoptotic genes is an early cellular change in Alzheimer's disease. Hum Mol Genet 2004; 13: 1225-1240.
-
(2004)
Hum Mol Genet
, vol.13
, pp. 1225-1240
-
-
Reddy, P.H.1
McWeeney, S.2
Park, B.S.3
Manczak, M.4
Gutala, R.V.5
Partovi, D.6
-
55
-
-
2642544767
-
Increased plaque burden in brains of APP mutant MnSOD heterozygous knockout mice
-
Li F, Calingasan NY, Yu F, Mauck WM, Toidze M, Almeida CG, et al. Increased plaque burden in brains of APP mutant MnSOD heterozygous knockout mice. J Neurochem 2004; 89: 1308-1312.
-
(2004)
J Neurochem
, vol.89
, pp. 1308-1312
-
-
Li, F.1
Calingasan, N.Y.2
Yu, F.3
Mauck, W.M.4
Toidze, M.5
Almeida, C.G.6
-
56
-
-
19944433845
-
®-Site APP cleaving enzyme up-regulation induced by 4-hydroxynonenal is mediated by stressactivated protein kinases pathways
-
Tamagno E, Parola M, Bardini P, Piccini A, Borghi R, Guglielmotto M, et al. ®-Site APP cleaving enzyme up-regulation induced by 4-hydroxynonenal is mediated by stressactivated protein kinases pathways. J Neurochem 2005; 92: 628-636.
-
(2005)
J Neurochem
, vol.92
, pp. 628-636
-
-
Tamagno, E.1
Parola, M.2
Bardini, P.3
Piccini, A.4
Borghi, R.5
Guglielmotto, M.6
-
57
-
-
12844250694
-
Induction of hyperphosphorylated tau in primary rat cortical neuron cultures mediated by oxidativestress and glycogen synthase kinase-3
-
Lovell MA, Xiong S, Xie C, Davies P, Markesbery WR. Induction of hyperphosphorylated tau in primary rat cortical neuron cultures mediated by oxidativestress and glycogen synthase kinase-3. J Alzheimers Dis 2004; 6: 659-671.
-
(2004)
J Alzheimers Dis
, vol.6
, pp. 659-671
-
-
Lovell, M.A.1
Xiong, S.2
Xie, C.3
Davies, P.4
Markesbery, W.R.5
-
58
-
-
1442314722
-
Early vitamin e supplementation in young but not aged mice reduces Abeta levels and amyloid deposition in a transgenic model of Alzheimer's disease
-
Sung S, Yao Y, Uryu K, Yang H, Lee VM, Trojanowski JQ, Pratico D. Early vitamin E supplementation in young but not aged mice reduces Abeta levels and amyloid deposition in a transgenic model of Alzheimer's disease. FASEB J 2004; 18: 323-325.
-
(2004)
FASEB J
, vol.18
, pp. 323-325
-
-
Sung, S.1
Yao, Y.2
Uryu, K.3
Yang, H.4
Lee, V.M.5
Trojanowski, J.Q.6
Pratico, D.7
-
59
-
-
71049178586
-
Antioxidants and cognitive training interact to aff ect oxidative stress and memory in APP/PSEN1 mice
-
Harrison FE, Allard J, Bixler R, Usoh C, Li L, May JM, McDonald MP. Antioxidants and cognitive training interact to aff ect oxidative stress and memory in APP/PSEN1 mice. Nutr Neurosci 2009; 12: 203-218.
-
(2009)
Nutr Neurosci
, vol.12
, pp. 203-218
-
-
Harrison, F.E.1
Allard, J.2
Bixler, R.3
Usoh, C.4
Li, L.5
May, J.M.6
McDonald, M.P.7
-
60
-
-
84878193469
-
Ferulic acid inhibits oxidative stress and cell death induced by A ®oligomers: Improved delivery by solid lipid nanoparticles
-
Picone P, Bondí ML, Montana G, Bruno A, Pitarresi G, Giammona G, Di Carlo M. Ferulic acid inhibits oxidative stress and cell death induced by A ®oligomers: improved delivery by solid lipid nanoparticles. Free Rad Res 2009; 3: 4200-4211.
-
(2009)
Free Rad Res
, vol.3
, pp. 4200-4211
-
-
Picone, P.1
Bondí, M.L.2
Montana, G.3
Bruno, A.4
Pitarresi, G.5
Giammona, G.6
Di Carlo, M.7
-
61
-
-
33750617659
-
The role of polyfenolic antioxidants in health, disease and aging
-
Obrenovich ME, Smith MA, Siedlak SL, Chen SG, de la Torre JC, Perry G, Aliev G. The role of polyfenolic antioxidants in health, disease and aging. Neurotox Res 2006; 10: 43-56.
-
(2006)
Neurotox Res
, vol.10
, pp. 43-56
-
-
Obrenovich, M.E.1
Smith, M.A.2
Siedlak, S.L.3
Chen, S.G.4
De La Torre, J.C.5
Perry, G.6
Aliev, G.7
-
62
-
-
0033681149
-
Chronic systemic pesticide exposure reproduces features of Parkinson's disease
-
Betarbet R, Sherer TB, MacKenzie G, Garcia-Osuna M, Panov AV, Greenamyre JT. Chronic systemic pesticide exposure reproduces features of Parkinson's disease. Nature Neurosci 2000; 3: 1301-1306.
-
(2000)
Nature Neurosci
, vol.3
, pp. 1301-1306
-
-
Betarbet, R.1
Sherer, T.B.2
MacKenzie, G.3
Garcia-Osuna, M.4
Panov, A.V.5
Greenamyre, J.T.6
-
63
-
-
20044385568
-
Parkinson-like syndrome induced by continuous MPTP infusion: Convergent roles of the ubiquitin-proteasome system and-synuclein
-
Fornai F, Schlüter OM, Lenzi P, Gesi M, Ruff oli R, Ferrucci M, et al. Parkinson-like syndrome induced by continuous MPTP infusion: convergent roles of the ubiquitin-proteasome system and-synuclein. Proc Natl Acad Sci USA 2005; 102: 3413-3418.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 3413-3418
-
-
Fornai, F.1
Schlüter, O.M.2
Lenzi, P.3
Gesi, M.4
Ruff Oli, R.5
Ferrucci, M.6
-
64
-
-
0037394420
-
1-Methyl-4-phenylpyridinium (MPPu)-induced apoptosis and mitochondrial oxidant generation: Role of transferrin-receptor-dependent iron and hydrogen peroxide
-
Kalivendi SV, Kotamraju S, Cunningham S, Shang T, Hillard CJ, Kalyanaraman B. 1-Methyl-4-phenylpyridinium (MPPu)-induced apoptosis and mitochondrial oxidant generation: role of transferrin-receptor-dependent iron and hydrogen peroxide. Biochem 2003; 371: 151-164.
-
(2003)
Biochem
, vol.371
, pp. 151-164
-
-
Kalivendi, S.V.1
Kotamraju, S.2
Cunningham, S.3
Shang, T.4
Hillard, C.J.5
Kalyanaraman, B.6
-
65
-
-
0025254401
-
Mitochondrial complex i defi ciency in Parkinson's disease
-
Schapira AHV, Cooper JM, Dexter D, Clark JB, Jenner P, Marsden CD. Mitochondrial complex I defi ciency in Parkinson's disease. J Neurochem 1990; 54: 823-827.
-
(1990)
J Neurochem
, vol.54
, pp. 823-827
-
-
Schapira, A.H.V.1
Cooper, J.M.2
Dexter, D.3
Clark, J.B.4
Jenner, P.5
Marsden, C.D.6
-
66
-
-
1542617769
-
Enhanced substantia nigra mitochondrial pathology in human-synuclein transgenic mice after treatment with MPTP
-
Song DD, Shults CW, Sisk A, Rockenstein E, Masliah E. Enhanced substantia nigra mitochondrial pathology in human-synuclein transgenic mice after treatment with MPTP. Exp Neurol 2004; 186: 158-172.
-
(2004)
Exp Neurol
, vol.186
, pp. 158-172
-
-
Song, D.D.1
Shults, C.W.2
Sisk, A.3
Rockenstein, E.4
Masliah, E.5
-
67
-
-
30644471051
-
Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death
-
Martin LJ, Pan Y, Price AC, Sterling W, Copeland NG, Jenkins NA, et al. Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death. J Neurosci 2006; 4: 41-50.
-
(2006)
J Neurosci
, vol.4
, pp. 41-50
-
-
Martin, L.J.1
Pan, Y.2
Price, A.C.3
Sterling, W.4
Copeland, N.G.5
Jenkins, N.A.6
-
68
-
-
0035957304
-
Mitochondrial myopathy, parkinsonism, and multiple mtDNA deletions in a Sephardic Jewish family
-
Casali C, Bonifati V, Santorelli FM, Casari G, Fortini D, Patrignani A, et al. Mitochondrial myopathy, parkinsonism, and multiple mtDNA deletions in a Sephardic Jewish family. Neurology 2001; 56: 802-805.
-
(2001)
Neurology
, vol.56
, pp. 802-805
-
-
Casali, C.1
Bonifati, V.2
Santorelli, F.M.3
Casari, G.4
Fortini, D.5
Patrignani, A.6
-
69
-
-
0034776305
-
Mitochondrial DNA rearrangements in young onset Parkinsonism: Two case reports
-
Siciliano G, Mancuso M, Ceravolo R, Lombardi V, Iudice A, Bonuccelli U. Mitochondrial DNA rearrangements in young onset Parkinsonism: two case reports. J Neurol Neurosurg Psychiat 2001; 71: 685-687.
-
(2001)
J Neurol Neurosurg Psychiat
, vol.71
, pp. 685-687
-
-
Siciliano, G.1
Mancuso, M.2
Ceravolo, R.3
Lombardi, V.4
Iudice, A.5
Bonuccelli, U.6
-
70
-
-
0033768121
-
A novel mitochondrial 12S rRNA point mutation in Parkinsonism, deafness and neuropathy
-
Thyagarajan D, Bressman S, Bruno C, Przedborski S, Shanske S, Lynch T, et al. A novel mitochondrial 12S rRNA point mutation in Parkinsonism, deafness and neuropathy. Ann Neurol 2000; 48: 730-736.
-
(2000)
Ann Neurol
, vol.48
, pp. 730-736
-
-
Thyagarajan, D.1
Bressman, S.2
Bruno, C.3
Przedborski, S.4
Shanske, S.5
Lynch, T.6
-
71
-
-
33646358693
-
Early-onset familial parkinsonism due to POLG mutations
-
Davidzon G, Greene P, Mancuso M, Klos KJ, Ahlskog JE, Hirano M, Di Mauro S. Early-onset familial parkinsonism due to POLG mutations. Ann Neurol 2006; 59: 859-862.
-
(2006)
Ann Neurol
, vol.59
, pp. 859-862
-
-
Davidzon, G.1
Greene, P.2
Mancuso, M.3
Klos, K.J.4
Ahlskog, J.E.5
Hirano, M.6
Di Mauro, S.7
-
72
-
-
4544273256
-
Parkinsonism, premature menopause, and mitochondrial DNA polymerase gamma mutations: Clinical and molecular genetic study
-
Luoma P, Melberg A, Rinne JO, Kaukonen JA, Nupponen NN, Chalmers RM, et al. Parkinsonism, premature menopause, and mitochondrial DNA polymerase gamma mutations: clinical and molecular genetic study. Lancet 2004; 364: 875-882.
-
(2004)
Lancet
, vol.364
, pp. 875-882
-
-
Luoma, P.1
Melberg, A.2
Rinne, J.O.3
Kaukonen, J.A.4
Nupponen, N.N.5
Chalmers, R.M.6
-
73
-
-
33751008071
-
POLG1 in idiopathic Parkinson disease
-
Tiangyou W, Hudson G, Ghezzi D, Ferrari G, Zeviani M, Burn DJ, Chinnery PF. POLG1 in idiopathic Parkinson disease. Neurology 2006; 67: 1698-1700.
-
(2006)
Neurology
, vol.67
, pp. 1698-1700
-
-
Tiangyou, W.1
Hudson, G.2
Ghezzi, D.3
Ferrari, G.4
Zeviani, M.5
Burn, D.J.6
Chinnery, P.F.7
-
74
-
-
0037428241
-
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
-
Bonifati V, Rizzu P, van Baren MJ, Schaap O, Breedveld GJ, Krieger E, et al. Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism. Science 2003; 299: 256-259.
-
(2003)
Science
, vol.299
, pp. 256-259
-
-
Bonifati, V.1
Rizzu, P.2
Van Baren, M.J.3
Schaap, O.4
Breedveld, G.J.5
Krieger, E.6
-
75
-
-
20744454444
-
DJ-1 is present in a large molecular complex in human brain tissue and interacts with alphasynuclein
-
Meulener MC, Graves CL, Sampathu DM, Armstrong-Gold CE, Bonini NM, Giasson BI. DJ-1 is present in a large molecular complex in human brain tissue and interacts with alphasynuclein. J Neurochem 2005; 93: 1524-1532.
-
(2005)
J Neurochem
, vol.93
, pp. 1524-1532
-
-
Meulener, M.C.1
Graves, C.L.2
Sampathu, D.M.3
Armstrong-Gold, C.E.4
Bonini, N.M.5
Giasson, B.I.6
-
76
-
-
12344251678
-
Association of DJ-1 and parkin mediated by pathogenic DJ-1 mutations and oxidative stress
-
Moore DJ, Zhang L, Troncoso J, Lee MK, Hattori N, Mizuno Y. Association of DJ-1 and parkin mediated by pathogenic DJ-1 mutations and oxidative stress. Hum Mol Genet 2004; 14: 71-84.
-
(2004)
Hum Mol Genet
, vol.14
, pp. 71-84
-
-
Moore, D.J.1
Zhang, L.2
Troncoso, J.3
Lee, M.K.4
Hattori, N.5
Mizuno, Y.6
-
77
-
-
2442668926
-
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
-
Valente EM, Abou-Sleiman PM, Caputo V, Muqit MM, Harvey K, Gispert S, et al. Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science 2004; 304: 1158-1160.
-
(2004)
Science
, vol.304
, pp. 1158-1160
-
-
Valente, E.M.1
Abou-Sleiman, P.M.2
Caputo, V.3
Muqit, M.M.4
Harvey, K.5
Gispert, S.6
-
78
-
-
28044460070
-
Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity
-
West AB, Moore DJ, Biskup S, Bugayenko A, Smith WW, Ross CA, et al. Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity. Proc Natl Acad Sci USA 2005; 102: 16842-16847.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 16842-16847
-
-
West, A.B.1
Moore, D.J.2
Biskup, S.3
Bugayenko, A.4
Smith, W.W.5
Ross, C.A.6
-
79
-
-
25444498785
-
Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease
-
Strauss KM, Martins LM, Plun-Favreau H, Marx FP, Kautzmann S, Berg D, et al. Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease. Hum Mol Genet 2005; 14: 2099-2111.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 2099-2111
-
-
Strauss, K.M.1
Martins, L.M.2
Plun-Favreau, H.3
Marx, F.P.4
Kautzmann, S.5
Berg, D.6
-
80
-
-
16844366080
-
Mitochondrial dysfunction and its role in motor neuron degeneration in ALS
-
Manfredi G, Xu Z. Mitochondrial dysfunction and its role in motor neuron degeneration in ALS. Mitochondrion 2005; 5: 77-87.
-
(2005)
Mitochondrion
, vol.5
, pp. 77-87
-
-
Manfredi, G.1
Xu, Z.2
-
81
-
-
0032539791
-
Impairment of mitochondrial function in skeletal muscle of patients with amyotrophic lateral sclerosis
-
Wiedemann FR, Winkler K, Kuznetsov AV, Bartels C, Vielhaber S, Feistner H, Kunz WS. Impairment of mitochondrial function in skeletal muscle of patients with amyotrophic lateral sclerosis. J Neurol Sci 1998; 156: 65-72.
-
(1998)
J Neurol Sci
, vol.156
, pp. 65-72
-
-
Wiedemann, F.R.1
Winkler, K.2
Kuznetsov, A.V.3
Bartels, C.4
Vielhaber, S.5
Feistner, H.6
Kunz, W.S.7
-
82
-
-
0033917463
-
Mitochondrial DNA abnormalities in skeletal muscle of patients with sporadic amyotrophic lateral sclerosis
-
Vielhaber S, Kunz D, Winkler K, Wiedemann FR, Kirches E, Feistner H. Mitochondrial DNA abnormalities in skeletal muscle of patients with sporadic amyotrophic lateral sclerosis. Brain 2000; 123: 1339-1348.
-
(2000)
Brain
, vol.123
, pp. 1339-1348
-
-
Vielhaber, S.1
Kunz, D.2
Winkler, K.3
Wiedemann, F.R.4
Kirches, E.5
Feistner, H.6
-
83
-
-
0344240348
-
ALS-associated mutant SOD1G93A causes mitochondrial vacuolation by expansion of the intermembrane space and by involvement of SOD1 aggregation and peroxisomes
-
Higgins CM, Jung C, Xu Z. ALS-associated mutant SOD1G93A causes mitochondrial vacuolation by expansion of the intermembrane space and by involvement of SOD1 aggregation and peroxisomes. BMC Neurosci 2003; 4: 16.
-
(2003)
BMC Neurosci
, vol.4
, pp. 16
-
-
Higgins, C.M.1
Jung, C.2
Xu, Z.3
-
84
-
-
14944385595
-
Mutant superoxide dismutase 1 forms aggregates in the brain mitochondrial matrix of amyotrophic lateral sclerosis mice
-
Vijayvergiya C, Beal MF, Buck J, Manfredi G. Mutant superoxide dismutase 1 forms aggregates in the brain mitochondrial matrix of amyotrophic lateral sclerosis mice. J. Neurosci 2005; 25: 2463-2470.
-
(2005)
J. Neurosci
, vol.25
, pp. 2463-2470
-
-
Vijayvergiya, C.1
Beal, M.F.2
Buck, J.3
Manfredi, G.4
-
85
-
-
33746215801
-
Cell culture models to investigate the selective vulnerability of motoneuronal mitochondria to familial ALS-linked G93ASOD1
-
Raimondi A, Mangolini A, Rizzardini M, Tartari S, Massari S, Bendotti C, et al. Cell culture models to investigate the selective vulnerability of motoneuronal mitochondria to familial ALS-linked G93ASOD1. Eur J Neurosci 2006; 24: 387-399.
-
(2006)
Eur J Neurosci
, vol.24
, pp. 387-399
-
-
Raimondi, A.1
Mangolini, A.2
Rizzardini, M.3
Tartari, S.4
Massari, S.5
Bendotti, C.6
-
86
-
-
0036310142
-
Mitochondrial dysfunction in a cell culture model of familial amyotrophic lateral sclerosis
-
Menzies FM, Cookson MR, Taylor RW, Turnbull DM, Chrzanowska-Lightowlers ZM, Dong L, et al. Mitochondrial dysfunction in a cell culture model of familial amyotrophic lateral sclerosis. Brain 2002; 125: 1522-1533.
-
(2002)
Brain
, vol.125
, pp. 1522-1533
-
-
Menzies, F.M.1
Cookson, M.R.2
Taylor, R.W.3
Turnbull, D.M.4
Chrzanowska- Lightowlers, Z.M.5
Dong, L.6
-
87
-
-
0032745071
-
Mitochondrial enzyme activity in amyotrophic lateral sclerosis: Implications for the role of mitochondria in neuronal cell death
-
Borthwick GM, Johnson MA, Ince PG, Shaw PJ, Turnbull DM. Mitochondrial enzyme activity in amyotrophic lateral sclerosis: implications for the role of mitochondria in neuronal cell death. Ann Neurol 1999; 46: 787-790.
-
(1999)
Ann Neurol
, vol.46
, pp. 787-790
-
-
Borthwick, G.M.1
Johnson, M.A.2
Ince, P.G.3
Shaw, P.J.4
Turnbull, D.M.5
-
88
-
-
0037086851
-
A quantitative histochemical assay for activities of mitochondrial electron transport chain complexes in mouse spinal cord sections
-
Jung C, Higgins CM, Xu Z. A quantitative histochemical assay for activities of mitochondrial electron transport chain complexes in mouse spinal cord sections. J Neurosci Methods 2002; 114: 165-172.
-
(2002)
J Neurosci Methods
, vol.114
, pp. 165-172
-
-
Jung, C.1
Higgins, C.M.2
Xu, Z.3
-
89
-
-
0031559896
-
Expression of a Cu, Zn superoxide dismutase typical of familial amyotrophic lateral sclerosis induces mitochondrial alteration and increase of cytosolic Ca2-concentration in transfected neuroblastoma SH-SY5Y cells
-
Carri MT, Ferri A, Battistoni A, Famhy L, Gabbianelli R, Poccia F, Rotilio G. Expression of a Cu, Zn superoxide dismutase typical of familial amyotrophic lateral sclerosis induces mitochondrial alteration and increase of cytosolic Ca2-concentration in transfected neuroblastoma SH-SY5Y cells. FEBS Lett 1997; 414: 365-368.
-
(1997)
FEBS Lett
, vol.414
, pp. 365-368
-
-
Carri, M.T.1
Ferri, A.2
Battistoni, A.3
Famhy, L.4
Gabbianelli, R.5
Poccia, F.6
Rotilio, G.7
-
90
-
-
0037119407
-
Mutated human SOD1 causes dysfunction of oxidative phosphorylation in mitochondria of transgenic mice
-
Mattiazzi M, D'Aurelio M, Gajewski CD, Martushova K, Kiaei M, Beal MF, Manfredi G. Mutated human SOD1 causes dysfunction of oxidative phosphorylation in mitochondria of transgenic mice. J Biol Chem 2002; 277: 29626-29633.
-
(2002)
J Biol Chem
, vol.277
, pp. 29626-29633
-
-
Mattiazzi, M.1
D'Aurelio, M.2
Gajewski, C.D.3
Martushova, K.4
Kiaei, M.5
Beal, M.F.6
Manfredi, G.7
-
91
-
-
0027359334
-
Superoxide dismutase activity, oxidative damage, and mitochondrial energy metabolism in familial and sporadic amyotrophic lateral sclerosis
-
Bowling AC, Schulz JB, Brown RH Jr, Beal MF. Superoxide dismutase activity, oxidative damage, and mitochondrial energy metabolism in familial and sporadic amyotrophic lateral sclerosis. J Neurochem 1993; 61: 2322-2325.
-
(1993)
J Neurochem
, vol.61
, pp. 2322-2325
-
-
Bowling, A.C.1
Schulz, J.B.2
Brown, Jr.R.H.3
Beal, M.F.4
-
92
-
-
3242701496
-
Toxicity of familial ALS-linked SOD1 mutants from selective recruitment to spinal mitochondria
-
Liu J, Lillo C, Jonsson PA, Van de Velde C, Ward CM, Miller TM, et al. Toxicity of familial ALS-linked SOD1 mutants from selective recruitment to spinal mitochondria. Neuron 2004; 43: 5-17.
-
(2004)
Neuron
, vol.43
, pp. 5-17
-
-
Liu, J.1
Lillo, C.2
Jonsson, P.A.3
Van De Velde, C.4
Ward, C.M.5
Miller, T.M.6
-
93
-
-
3242703300
-
Amyotrophic lateral sclerosisassociated SOD1 mutant proteins bind and aggregate with Bcl-2 in spinal cord mitochondria
-
Pasinelli P, Belford ME, Lennon N, Bacskai BJ, Hyman BT, Trotti D, Brown RH Jr. Amyotrophic lateral sclerosisassociated SOD1 mutant proteins bind and aggregate with Bcl-2 in spinal cord mitochondria. Neuron 2004; 43: 19-30.
-
(2004)
Neuron
, vol.43
, pp. 19-30
-
-
Pasinelli, P.1
Belford, M.E.2
Lennon, N.3
Bacskai, B.J.4
Hyman, B.T.5
Trotti, D.6
Brown Jr., R.H.7
-
94
-
-
33748795566
-
Familial ALS-superoxide dismutases associate with mitochondria and shift their redox potentials
-
Ferri A, Cozzolino M, Crosio C, Nenc ini M, Casciati A, Gralla EB, et al. Familial ALS-superoxide dismutases associate with mitochondria and shift their redox potentials. Proc Natl Acad Sci USA 2006; 103: 13860-13865.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 13860-13865
-
-
Ferri, A.1
Cozzolino, M.2
Crosio, C.3
Nenc Ini, M.4
Casciati, A.5
Gralla, E.B.6
-
96
-
-
0035106351
-
Large-scale analysis of the yeast proteome by multidimensional protein identifi cation technology
-
Washburn MP, Wolters D, Yates JR 3rd. Large-scale analysis of the yeast proteome by multidimensional protein identifi cation technology. Nat Biotechnol 2001; 19: 242-247.
-
(2001)
Nat Biotechnol
, vol.19
, pp. 242-247
-
-
Washburn, M.P.1
Wolters, D.2
Yates, Iii.J.R.3
-
97
-
-
1842505677
-
Proteomics: A new approach to investigate oxidative stress in Alzheimer's disease brain
-
Butterfield DA. Proteomics: a new approach to investigate oxidative stress in Alzheimer's disease brain. Brain Res 2004; 1000: 1-7.
-
(2004)
Brain Res
, vol.1000
, pp. 1-7
-
-
Butterfield, D.A.1
-
98
-
-
0032875697
-
Quantitative analysis of complex protein mixtures using isotope-coded affi nity tags
-
Gygi SP, Rist B, Gerber SA, Turecek F, Gelb MH, Aebersold R. Quantitative analysis of complex protein mixtures using isotope-coded affi nity tags. Nat Biotechnol 1999; 17: 994-999.
-
(1999)
Nat Biotechnol
, vol.17
, pp. 994-999
-
-
Gygi, S.P.1
Rist, B.2
Gerber, S.A.3
Turecek, F.4
Gelb, M.H.5
Aebersold, R.6
-
99
-
-
0034066471
-
Membrane proteins and proteomics: Un amour impossible?
-
Santoni V, Molloy M, Rabilloud T. Membrane proteins and proteomics: un amour impossible?. Electrophoresis 2000; 21: 1054-1070.
-
(2000)
Electrophoresis
, vol.21
, pp. 1054-1070
-
-
Santoni, V.1
Molloy, M.2
Rabilloud, T.3
-
100
-
-
34548588380
-
Redox proteomics identifi cation of oxidatively modifi ed brain proteins in Alzheimer's disease and mild cognitive impairment: Insights into the progression of this dementing disorder
-
Butterfield DA, Sultana R. Redox proteomics identifi cation of oxidatively modifi ed brain proteins in Alzheimer's disease and mild cognitive impairment: insights into the progression of this dementing disorder. J Alzheimers Dis 2007; 12: 61-72.
-
(2007)
J Alzheimers Dis
, vol.12
, pp. 61-72
-
-
Butterfield, D.A.1
Sultana, R.2
-
101
-
-
2942659505
-
Quantitative proteomics analysis of specifi c protein expression and oxidative modifi cation in aged senescence-accelerated-prone 8 mice brain
-
Poon HF, Castegna A, Farr SA, Thongboonkerd V, Lynn BC, Banks WA, et al. Quantitative proteomics analysis of specifi c protein expression and oxidative modifi cation in aged senescence-accelerated-prone 8 mice brain. Neuroscience 2004; 126: 915-926.
-
(2004)
Neuroscience
, vol.126
, pp. 915-926
-
-
Poon, H.F.1
Castegna, A.2
Farr, S.A.3
Thongboonkerd, V.4
Lynn, B.C.5
Banks, W.A.6
-
102
-
-
0036709007
-
Proteomic analysis of protein oxidation in Alzheimer's disease brain
-
Korolainen MA, Goldsteins G, Alafuzoff I, Koistinaho J, Pirttila T. Proteomic analysis of protein oxidation in Alzheimer's disease brain. Electrophoresis 2002; 23: 3428-3433.
-
(2002)
Electrophoresis
, vol.23
, pp. 3428-3433
-
-
Korolainen, M.A.1
Goldsteins, G.2
Alafuzoff, I.3
Koistinaho, J.4
Pirttila, T.5
-
103
-
-
0038472495
-
Proteomic identifi cation of nitrated proteins in Alzheimer's disease brain
-
Castegna A, Thongboonkerd V, Klein JB, Lynn B, Markesbery WR, Butterfield DA. Proteomic identifi cation of nitrated proteins in Alzheimer's disease brain. J Neurochem 2003; 85: 1394-1401.
-
(2003)
J Neurochem
, vol.85
, pp. 1394-1401
-
-
Castegna, A.1
Thongboonkerd, V.2
Klein, J.B.3
Lynn, B.4
Markesbery, W.R.5
Butterfield, D.A.6
-
104
-
-
22544448129
-
Redox proteomics analysis of oxidatively modifi ed proteins in G93A-SOD1 transgenic mice. A model of familial amyotrophic lateral sclerosis
-
Poon HF, Hensley K, Thongboonkerd V, Merchant ML, Lynn BC, Pierce WM, et al. Redox proteomics analysis of oxidatively modifi ed proteins in G93A-SOD1 transgenic mice. A model of familial amyotrophic lateral sclerosis. Free Radic Biol Med 2005; 39: 453-462.
-
(2005)
Free Radic Biol Med
, vol.39
, pp. 453-462
-
-
Poon, H.F.1
Hensley, K.2
Thongboonkerd, V.3
Merchant, M.L.4
Lynn, B.C.5
Pierce, W.M.6
-
105
-
-
4344604345
-
Selectivity of protein carbonylation in the apoptotic response to oxidative stress associated with photodynamic therapy: A cell biochemical and proteomic investigation
-
Magi B, Ettorre A, Liberatori S, Bini L, Andreassi M, Frosali S, et al. Selectivity of protein carbonylation in the apoptotic response to oxidative stress associated with photodynamic therapy: a cell biochemical and proteomic investigation. Cell Death Diff er 2004; 11: 842-852.
-
(2004)
Cell Death Diff Er
, vol.11
, pp. 842-852
-
-
Magi, B.1
Ettorre, A.2
Liberatori, S.3
Bini, L.4
Andreassi, M.5
Frosali, S.6
-
106
-
-
14644400490
-
Proteomic analysis of 4-hydroxy-2-nonenal-modifi ed proteins in G93ASOD1 transgenic mice-A model of familial amyotrophic lateral sclerosis
-
Perluigi M, Fai Poon H, Hensley K, Pierce WM, Klein JB, Calabrese V, et al. Proteomic analysis of 4-hydroxy-2-nonenal-modifi ed proteins in G93ASOD1 transgenic mice-a model of familial amyotrophic lateral sclerosis. Free Radic Biol Med 2005; 38: 960-968.
-
(2005)
Free Radic Biol Med
, vol.38
, pp. 960-968
-
-
Perluigi, M.1
Fai Poon, H.2
Hensley, K.3
Pierce, W.M.4
Klein, J.B.5
Calabrese, V.6
-
107
-
-
10644231017
-
Mitochondrial proteomics in free radical research Free
-
Bailey SM, Landar A, Darley-Usmar V. Mitochondrial proteomics in free radical research Free. Radic Biol Med 2005; 38: 175-188.
-
(2005)
Radic Biol Med
, vol.38
, pp. 175-188
-
-
Bailey, S.M.1
Landar, A.2
Darley-Usmar, V.3
-
108
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004; 116: 281-297.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
109
-
-
33751254116
-
The neuronal microRNA system
-
Kosik KS. The neuronal microRNA system. Nat Rev Neurosci 2006; 7: 911-920.
-
(2006)
Nat Rev Neurosci
, vol.7
, pp. 911-920
-
-
Kosik, K.S.1
-
111
-
-
34548177451
-
Induction of specifi c micro RNA(miRNA) species by ROS-generating metal sulfates in primary human brain cells
-
Lukiw WJ, Pogue AI. Induction of specifi c micro RNA(miRNA) species by ROS-generating metal sulfates in primary human brain cells. J Inorg Biochem 2007; 101: 1265-1269.
-
(2007)
J Inorg Biochem
, vol.101
, pp. 1265-1269
-
-
Lukiw, W.J.1
Pogue, A.I.2
-
112
-
-
33847203593
-
MicroRNA speciation in fetal, adult and Alzheimer's disease hippocampus
-
Lukiw WJ. MicroRNA speciation in fetal, adult and Alzheimer's disease hippocampus. Neuroreport 2007; 18: 297-300.
-
(2007)
Neuroreport
, vol.18
, pp. 297-300
-
-
Lukiw, W.J.1
-
113
-
-
77955294582
-
MicroRNA 128a increases intracellular ROS level by targeting Bmi-1 and inhibits medulloblastoma cancer cell growth by promoting senescence
-
Venkataraman S, Alimova I, Fan R, Harris P, Foreman N, Vibhakar R. MicroRNA 128a increases intracellular ROS level by targeting Bmi-1 and inhibits medulloblastoma cancer cell growth by promoting senescence. PloSONE 2010; 5: 1-10.
-
(2010)
PloSONE
, vol.5
, pp. 1-10
-
-
Venkataraman, S.1
Alimova, I.2
Fan, R.3
Harris, P.4
Foreman, N.5
Vibhakar, R.6
-
114
-
-
33748749597
-
MicroRNA-9 controls the expression of Granuphilin/Slp4 and the secretory response of insulinproducing cells
-
Plaisance V, Abderrahmani A, Perret-Menoud V, Jacquemin P, Lemaigre F, Regazzi R. MicroRNA-9 controls the expression of Granuphilin/Slp4 and the secretory response of insulinproducing cells. J Biol Chem 2006; 281: 2: 6932-26942.
-
(2006)
J Biol Chem
, vol.281
, pp. 26932-26942
-
-
Plaisance, V.1
Abderrahmani, A.2
Perret-Menoud, V.3
Jacquemin, P.4
Lemaigre, F.5
Regazzi, R.6
-
115
-
-
58149375393
-
The bifunctional microRNA miR-9/miR-9 * regulates REST and CoREST and is downregulated in Huntington's disease
-
Packer AN, Xing Y, Harper SQ, Jones L, Davidson BL. The bifunctional microRNA miR-9/miR-9 * regulates REST and CoREST and is downregulated in Huntington's disease. J Neurosci 2008; 28: 14341-14346.
-
(2008)
J Neurosci
, vol.28
, pp. 14341-14346
-
-
Packer, A.N.1
Xing, Y.2
Harper, S.Q.3
Jones, L.4
Davidson, B.L.5
-
116
-
-
64049095014
-
A feedback regulatory loop involving microRNA-9 and nuclear receptor TLX in neural stem cell fate determination
-
Zhao C, Sun G, Li S, Shi Y. A feedback regulatory loop involving microRNA-9 and nuclear receptor TLX in neural stem cell fate determination. Nat Struct Mol Biol 2009; 16: 365-371.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 365-371
-
-
Zhao, C.1
Sun, G.2
Li, S.3
Shi, Y.4
-
117
-
-
70349263692
-
MicroRNA-9 inhibits ovarian cancer cell growth through regulation of NF-kappaB1
-
Guo LM, Pu Y, Han Z, Liu T, Li YX, Liu M, et al. MicroRNA-9 inhibits ovarian cancer cell growth through regulation of NF-kappaB1. FEBS J 2009; 276: 5537-5546.
-
(2009)
FEBS J
, vol.276
, pp. 5537-5546
-
-
Guo, L.M.1
Pu, Y.2
Han, Z.3
Liu, T.4
Li, Y.X.5
Liu, M.6
-
118
-
-
79960135400
-
MicroRNA profi ling of Parkinson's disease brains identifi es early downregulation of miR-34b/c which modulate mitochondrial function
-
Miñ ones-Moyano E, Porta S, Escaram ís G, Rabionet R, Iraola S, Kagerbauer B, et al. MicroRNA profi ling of Parkinson's disease brains identifi es early downregulation of miR-34b/c which modulate mitochondrial function. Hum Mol Genet 2011; 20: 3067-3078.
-
(2011)
Hum Mol Genet
, vol.20
, pp. 3067-3078
-
-
Miñones-Moyano, E.1
Porta, S.2
Escaram Ís, G.3
Rabionet, R.4
Iraola, S.5
Kagerbauer, B.6
-
119
-
-
34548138278
-
Epigenetics: A historical overview
-
Holliday R. Epigenetics: a historical overview. Epigenetics 2006; 1: 76-80.
-
(2006)
Epigenetics
, vol.1
, pp. 76-80
-
-
Holliday, R.1
-
120
-
-
0036144048
-
DNA methylation patterns and epigenetic memory
-
Bird A. DNA methylation patterns and epigenetic memory. Genes Dev 2002; 16: 6-21.
-
(2002)
Genes Dev
, vol.16
, pp. 6-21
-
-
Bird, A.1
-
121
-
-
48449090298
-
Epigenetic biomarkers for human cancer: The time is now
-
Mulero-Navarro S, Esteller M. Epigenetic biomarkers for human cancer: the time is now. Crit Rev Oncol Hematol 2008; 68: 1-11.
-
(2008)
Crit Rev Oncol Hematol
, vol.68
, pp. 1-11
-
-
Mulero-Navarro, S.1
Esteller, M.2
-
122
-
-
49949108971
-
Age-specifi c epigenetic drift in late-onset Alzheimer's disease
-
Wang SC, Oelze B, Schumacher A. Age-specifi c epigenetic drift in late-onset Alzheimer's disease. PLoS ONE 2008; 3: e2698.
-
(2008)
PLoS ONE
, vol.3
-
-
Wang, S.C.1
Oelze, B.2
Schumacher, A.3
-
123
-
-
0027096062
-
Oxidants are a major contributor to aging
-
Ames BN, Shigenaga MK. Oxidants are a major contributor to aging. Ann NY Acad Sci 1992; 663: 85-96.
-
(1992)
Ann NY Acad Sci
, vol.663
, pp. 85-96
-
-
Ames, B.N.1
Shigenaga, M.K.2
-
124
-
-
4043112183
-
Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2)
-
Valinluck V, Tsai HH, Rogstad DK, Burdzy A, Bird A, Sowers LC. Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2). Nucleic Acids Res 2004; 32: 4100-4108.
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 4100-4108
-
-
Valinluck, V.1
Tsai, H.H.2
Rogstad, D.K.3
Burdzy, A.4
Bird, A.5
Sowers, L.C.6
-
125
-
-
0030816108
-
Cloning and characterization of hOGG1, a human homolog of the OGG1 gene of Saccharomyces cerevisiae
-
Radicella JP, Dherin C, Desmaze C, Fox MS, Boiteux S. Cloning and characterization of hOGG1, a human homolog of the OGG1 gene of Saccharomyces cerevisiae. Proc Natl Acad Sci USA 1997; 94: 8010-8015.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 8010-8015
-
-
Radicella, J.P.1
Dherin, C.2
Desmaze, C.3
Fox, M.S.4
Boiteux, S.5
-
126
-
-
34250350823
-
Identifi cation and characterization of OGG1 mutations in patients with Alzheimer's disease
-
Mao G, Pan X, Zhu BB, Zhang Y, Yuan F, Huang J, et al. Identifi cation and characterization of OGG1 mutations in patients with Alzheimer's disease. Nucleic Acids Res 2007; 35: 2759-2766.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 2759-2766
-
-
Mao, G.1
Pan, X.2
Zhu, B.B.3
Zhang, Y.4
Yuan, F.5
Huang, J.6
-
127
-
-
38049010515
-
Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimer's disease
-
Lovell MA, Markesbery WR. Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimer's disease. Nucleic Acids Res 2007; 35: 7497-7504.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 7497-7504
-
-
Lovell, M.A.1
Markesbery, W.R.2
-
128
-
-
0020574597
-
Neuropsychological studies in children with elevated tooth-lead concentrations. II. Extended study
-
Winneke G, Kramer U, Brockhaus A, Ewers U, Kujanek G, Lechner H, Janke W. Neuropsychological studies in children with elevated tooth-lead concentrations. II. Extended study. Int Arch Occup Environ Health 1983; 51: 231-252.
-
(1983)
Int Arch Occup Environ Health
, vol.51
, pp. 231-252
-
-
Winneke, G.1
Kramer, U.2
Brockhaus, A.3
Ewers, U.4
Kujanek, G.5
Lechner, H.6
Janke, W.7
-
130
-
-
0036225082
-
Lead exposure and amyotrophic lateral sclerosis
-
Kamel F, Umbach DM, Munsat TL, Shefner JM, Hu H, Sandler DP. Lead exposure and amyotrophic lateral sclerosis. Epidemiology 2002; 13: 311-319.
-
(2002)
Epidemiology
, vol.13
, pp. 311-319
-
-
Kamel, F.1
Umbach, D.M.2
Munsat, T.L.3
Shefner, J.M.4
Hu, H.5
Sandler, D.P.6
-
131
-
-
0036105984
-
ApoE genotype, past adult lead exposure, and neuro behavioral function
-
Stewart WF, Schwartz BS, Simon D, Kelsey K, Todd AC. ApoE genotype, past adult lead exposure, and neuro behavioral function. Environ Health Perspect 2002; 110: 501-505.
-
(2002)
Environ Health Perspect
, vol.110
, pp. 501-505
-
-
Stewart, W.F.1
Schwartz, B.S.2
Simon, D.3
Kelsey, K.4
Todd, A.C.5
-
132
-
-
38149024924
-
Alzheimer's disease (AD)-like pathology in aged monkeys after infantile exposure to environmental metal lead (Pb): Evidence for a developmental origin and environmental link for AD
-
Wu J, Basha MR, Brock B, Cox DP, Cardozo-Pelaez F, McPherson CA, et al. Alzheimer's disease (AD)-like pathology in aged monkeys after infantile exposure to environmental metal lead (Pb): evidence for a developmental origin and environmental link for AD. J Neurosci 2008; 28: 3-9.
-
(2008)
J Neurosci
, vol.28
, pp. 3-9
-
-
Wu, J.1
Basha, M.R.2
Brock, B.3
Cox, D.P.4
Cardozo-Pelaez, F.5
McPherson, C.A.6
-
133
-
-
33646236916
-
Exposure to lead and the developmental origin of oxidative DNA damage in the aging brain
-
Bolin CM, Basha R, Cox D, Zawia NH, Maloney B, Lahiri DK, Cardozo-Pelaez F. Exposure to lead and the developmental origin of oxidative DNA damage in the aging brain. FASEB J 2006; 20: 788-790.
-
(2006)
FASEB J
, vol.20
, pp. 788-790
-
-
Bolin, C.M.1
Basha, R.2
Cox, D.3
Zawia, N.H.4
Maloney, B.5
Lahiri, D.K.6
Cardozo-Pelaez, F.7
-
134
-
-
2542461039
-
Factors contributing to the outcome of oxidative damage to nucleic acids
-
Evans MD, Cooke MS. Factors contributing to the outcome of oxidative damage to nucleic acids. Bioessays 2004; 26: 533-542.
-
(2004)
Bioessays
, vol.26
, pp. 533-542
-
-
Evans, M.D.1
Cooke, M.S.2
|