MicroRNA 128a increases intracellular ROS level by targeting Bmi-1 and inhibits medulloblastoma cancer cell growth by promoting senescence

PLoS ONE

Volumn 5, Issue 6, 2010, Pages

  Venkataraman, Sujatha ^a   Alimova, Irina ^a   Fan, Rong ^c   Harris, Peter ^a   Foreman, Nicholas ^a,b   Vibhakar, Rajeev ^a,b,c  

^a Children's Hospital Colorado   (United States)

^b CHILDREN S HOSPITAL COLORADO   (United States)

^c UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BMI1 PROTEIN; MICRORNA; MICRORNA 128A; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; UNCLASSIFIED DRUG; BMI1 PROTEIN, HUMAN; MIRN128 MICRORNA, HUMAN; NUCLEAR PROTEIN; ONCOPROTEIN; REPRESSOR PROTEIN;

ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; DOWN REGULATION; GROWTH INHIBITION; HUMAN; HUMAN CELL; HUMAN TISSUE; MEDULLOBLASTOMA; NERVE CELL DIFFERENTIATION; ONCOGENE; OXIDATION REDUCTION STATE; PROTEIN TARGETING; SENESCENCE; SIGNAL TRANSDUCTION; STEADY STATE; TUMOR CELL; BRAIN; CELL AGING; CELL PROLIFERATION; GENE EXPRESSION REGULATION; GENETICS; INTRACELLULAR SPACE; METABOLISM; NUCLEOTIDE SEQUENCE; PATHOLOGY; TUMOR CELL LINE;

BASE SEQUENCE; BRAIN; CELL AGING; CELL LINE, TUMOR; CELL PROLIFERATION; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTRACELLULAR SPACE; MEDULLOBLASTOMA; MICRORNAS; NUCLEAR PROTEINS; PROTO-ONCOGENE PROTEINS; REACTIVE OXYGEN SPECIES; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; SUPEROXIDES;

EID: 77955294582     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0010748     Document Type: Article

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