Age-related changes in the concentrations of major and trace elements in the brain of rats and mice

Biological Trace Element Research

Volumn 80, Issue 2, 2001, Pages 145-158

  Takahashi, S ^a   Takahashi, I ^b   Sato, H ^a   Kubota, Y ^a   Yoshida, S ^a   Muramatsu, Y ^a  

^a NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^b Nuclear Service Co Ltd   (Japan)

Author keywords

Age; Brain; Major element; Mouse; Rat; Trace element

Indexed keywords

ALUMINUM; CADMIUM; CALCIUM; CESIUM; COBALT; COPPER; IRON; LEAD; MAGNESIUM; MANGANESE; MOLYBDENUM; PHOSPHORUS; POTASSIUM; RUBIDIUM; SODIUM; STRONTIUM; TRACE ELEMENT; ZINC;

AGING; ANIMAL TISSUE; ARTICLE; ATOMIC EMISSION SPECTROMETRY; BRAIN LEVEL; CORRELATION FUNCTION; MOUSE; NONHUMAN; RAT; REPRODUCIBILITY; TISSUE PREPARATION;

AGING; ANIMALS; BRAIN CHEMISTRY; ELEMENTS; FEMALE; MASS SPECTROMETRY; MICE; MICE, INBRED C3H; RATS; RATS, WISTAR; SPECIES SPECIFICITY; TRACE ELEMENTS;

ANIMALIA;

EID: 0034976070     PISSN: 01634984     EISSN: None     Source Type: Journal    
DOI: 10.1385/BTER:80:2:145     Document Type: Article

References (48)

1. Regional distribution of lead, zinc, iron and copper in suckling and adult rat brains
2. Quantification of trace elements in normal human brain by inductively coupled plasma atomic emission spectrometry
3. Changes in ionic fluxes during cerebral ischemia
4. Effect of high dose corticosteroid therapy on blood flow, evoked potentials, and extracellular calcium in experimental spinal injury
5. Tissue Na, K, and Ca changes in regional cerebral ischemia: Their measurement and interpretation
6. Potassium and calcium changes in injured spinal cords
7. Changes in extracellular potassium concentration in cortex and brain stem during the acute phase of experimental closed head injury
8. Effects of anoxia on ion distribution in the brain
9. Concentration of elements in human brain: Glioblastoma multiforme
10. Increased nigral iron content and alterations in other metal ions occurring in brain in Parkinson's disease
11. Brain manganese concentrations in human aging and Alzheimer's disease
12. Alterations in trace elements during brain aging and in Alzheimer's dementia
13. Zinc and Alzheimer's disease
14. Age related changes in weight and the concentrations of zinc and copper in the brain of the adult rat
15. Changes in brain trace element concentration by aging
16. The effect of aging on the mineral status of female mice
17. Alterations in tissue element and ascorbic acid metabolism in phenytoin-fed rats and mice
18. Effect of age and dietary protein level on tissue mineral levels in female rats
19. The effects of age and sex on seven elements in Sprague-Dawley rat organs
20. Changes with age in copper and superoxide dismutase levels in brains of C57BL/6J mice
21. Variations in trace metal levels in rat hippocampus during ontogenetic development
22. Mass spectrometry of trace elements in biological samples
23. Determination of major and trace elements in the liver of Wistar rats by inductively coupled plasma-atom emission spectrometry and mass spectrometry
24. Determination of major and trace elements in Japanese rock reference samples by ICP-MS
25. Determination of major and trace elements in mushroom, plant and soil samples collected from Japanese forests
26. Distribution of 14 elements in various rat tissues following hypophysectomy, thyroparathyroidectomy, adrenalectomy, and castration
27. Effects of adrenalectomy and of adrenal hormones on the tissue distribution of 14 elements in the rat
28. Determination of iron, copper, zinc, rubidium, molybdenum and cesium in human serum by inductively coupled plasma mass spectrometry
29. Trace elements in coronary heart disease
30. Changes in iron, calcium, magnesium, copper, and zinc levels in different tissues of riboflavin-deficient rats
31. Rapid changes in concentrations of essential elements in organs of rats exposed to methylmercury chloride and mercuric chloride as shown by simultaneous multielemental analysis
32. Effect of dietary iron deficiency on mineral levels in tissues of rats
33. Combined exposure to lead and ethanol on tissue concentration of essential metals and some biochemical indices in rat
34. The effect of cadmium pretreatment on the disposition and excretion of methylmercury and trace elements (zinc, copper) in rats
35. Effect of cadmium chelating agents on organ cadmium and trace element levels in mice
36. Studies on changes in trace elements of the brain related to aging
37. Influence of nicotine on tissue trace element concentrations and tissue antioxidant defense
38. Age related changes in weight and the concentrations of zinc and copper in the brain of the adult rat
39. Changes with age in cadmium and copper levels in C57BL/6J mice
40. 2+ in rat brain regions
41. Iron accumulation and lipid peroxidation in aging C57BL/6J mice
42. An application of neutron activation analysis to small biological samples: Simultaneous determination of thirty elements in rat brain regions
43. Copper and zinc distributions in eight regions and subcellular fractions of rat brain
44. Neuronal death in the development and aging of the cerebral cortex of the mouse
45. Dopamine, 6-hydroxydopamine, iron, and dioxygen - Their mutual interactions and possible implication in the development of Parkinson's disease
46. Increased iron in the substantia nigra of 6-OHDA induced parkinsonian rats: A nuclear microscopy study
47. Formation of DNA adducts and oxidative base damage by copper mediated oxidation of dopamine and 6-Hydroxydopamine
48. Manganese induced hydroxyl radical formation in rat striatum is not attenuated by dopamine depletion or iron chelation in vivo