ApoE genotype, past adult lead exposure, and neurobehavioral function

Environmental Health Perspectives

Volumn 110, Issue 5, 2002, Pages 501-505

  Stewart, Walter F ^a   Schwartz, Brian S ^a   Simon, David ^a   Kelsey, Karl ^a   Todd, Andrew C ^a  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Apolipoprotein E; Bone lead; Cognitive function; Neurobehavioral tests; X ray fluorescence

Indexed keywords

APOLIPOPROTEIN E; LEAD; ORGANOLEAD COMPOUND;

ADULT; AGED; ALLELE; ARTICLE; BONE LEVEL; BRAIN TOXICITY; COGNITION; CONTROLLED STUDY; GENETIC PREDISPOSITION; GENOTYPE; HUMAN; HUMAN EXPERIMENT; INDUSTRIAL WORKER; LEAD POISONING; LINEAR REGRESSION ANALYSIS; LONG TERM EXPOSURE; MALE; OCCUPATIONAL EXPOSURE; PRIORITY JOURNAL; PSYCHOLOGIC TEST; SCORING SYSTEM; STATISTICAL MODEL; STATISTICAL SIGNIFICANCE; TIBIA; X RAY FLUORESCENCE;

EID: 0036105984     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.02110501     Document Type: Article

References (47)

1. The relation between neurobehavioral function and tibial and chelatable lead levels in former organolead manufacturing workers
2. Past adult lead exposure is associated with longitudinal decline in cognitive function
3. Synergistic effects of traumatic head injury and Apo-ε4 in patients with Alzheimer's disease
4. Apolipoprotein E ε-4 allele is associated with deposition of amyloid β-protein following head injury
5. ApoE as a prognostic factor for post-traumatic coma
6. Apolipoprotein E ε4 associated with chronic traumatic brain injury in boxing
7. Apolipoprotein E-ε4 genotype predicts a poor outcome in survivors of traumatic brain injury
8. Decrements in neurobehavioral performance associated with mixed exposure to organic and inorganic lead
9. Symptom Checklist-90-R: Administration, Scoring, and Procedures Manual
10. Assessing depressive symptoms in five psychiatric populations: A validation study
11. 109Cd sources: Radiation dosimetry studies
12. 109Cd spot source
13. Calculating bone-lead measurement variance
14. Bone lead as a biological marker in epidemiologic studies of chronic toxicity: Conceptual paradigms
15. In vivo measurements of lead in bone in long-term exposed lead smelter workers
16. Characterization of toxicokinetics and toxicodynamics with linear systems theory: Application to lead associated cognitive decline
17. Restriction isotyping of human apolipoprotein-ε by gene amplification and cleavage with Hhal
18. Generalized Linear Models
19. Apolipoprotein-E and Alzheimer's disease: Ethnic variation in genotype risks
20. Apolipoprotein E-associated risk for Alzheimer's disease in the African American population is genotype dependent
21. Apolipoprotein E ε4 and the risk of dementia with stroke: A population based investigation
22. Beta A4 amyloid protein deposition in brain after head trauma
23. β-Amyloid protein deposition in the brain after severe head injury: Implications for the pathogenesis of Alzheimer's disease
24. Triethyllead and cerebral development: An overview
25. The interaction of tetraethyl lead with tubulin and microtubules
26. Neurobehavioral toxicology of the organoleads
27. The effect of triethyl lead on total and myelin protein synthesis in rat forebrain slices
28. Trimethyl lead neurotoxicity in the rat: Changes in glial fibrillary acidic protein (GFAP)
29. Chronic lead exposure induces astrogliosis in hippocampus and cerebellum
30. Lead-induced alterations of glial fibrillary acidic protein (GFAP) in the developing rat brain
31. Dose-dependent bimodal effect of low-level lead exposure on the developing hippocampal region of the rat: A volumetric study
32. Lead neurotoxicity
33. Neurofibrillary changes after acute experimental lead poisoning
34. Triethyl and trimethyl lead: Effects on behavior, CNS morphology, and concentrations of lead in blood and brain of rat
35. Low-level lead-induced neurotoxicity in children: An update on central nervous system effects
36. Developmental lead exposure alters the distribution of protein kinase C activity in the rat hippocampus
37. Synaptic plasticity in the CA1 and CA3 hippocampal region of pre- and postnatally lead-exposed rats
38. Nitric oxide synthase inhibitors L-NAME and 7-nitroindazole protect rat hippocampus against kainate-induced excitotoxicity
39. Region-specific alterations in dopamine and serotonin metabolism in brains of rats exposed to low levels of lead
40. Inorganic lead may inhibit neurite development in cultured rat hippocampal neurons through hyperphosphorylation
41. Glycine and calcium-dependent effects of lead on N-methyl-D-aspartate receptor function in rat hippocampal neurons
42. Influence of toxicants on neural cell adhesion molecule-mediated neuroplasticity in the developing and adult animal: Persistent effects of chronic perinatal low-level lead exposure
43. Melatonin plays a protective role in quinolinic acid-induced neurotoxicity in the rat hippocampus
44. 3H] hemicholinium-3 binding sites in hippocampus of developmental rats following perinatal low-level lead exposure
45. Nitric oxide affects LTP in area CA1 and CA3 of hippocampus in low-level lead-exposed rat
46. Prenatal and postnatal chronic exposure to low levels of inorganic lead attenuates longterm potentiation in the adult rat hippocampus in vivo
47. 3H-DL-Glu binding in the hippocampus of rat brain by lead