-
1
-
-
0034443957
-
Heterogeneity of therapeutic responses in asthma
-
Drazen JM, Silverman EK, Lee TH. Heterogeneity of therapeutic responses in asthma. Br. Med. Bull. 56(4), 1054-1070 (2000
-
(2000)
Br. Med. Bull.
, vol.56
, Issue.4
, pp. 1054-1070
-
-
Drazen, J.M.1
Silverman, E.K.2
Lee, T.H.3
-
2
-
-
77955873331
-
Using genetics to predict the natural history of asthma
-
quiz 210-211
-
Holloway JW, Arshad SH, Holgate ST. Using genetics to predict the natural history of asthma? J. Allergy Clin. Immunol. 126(2), 200-209; quiz 210-211 (2010
-
(2010)
J. Allergy Clin. Immunol.
, vol.126
, Issue.2
, pp. 200-209
-
-
Holloway, J.W.1
Arshad, S.H.2
Holgate, S.T.3
-
3
-
-
79952103287
-
Gene-environment interactions in human disease: Muisance or opportunity?
-
Ober C, Vercelli D. Gene-environment interactions in human disease: Muisance or opportunity? Trends Genet. 27(3), 107-115 (2011
-
(2011)
Trends Genet
, vol.27
, Issue.3
, pp. 107-115
-
-
Ober, C.1
Vercelli, D.2
-
4
-
-
84860679595
-
Asthma phenotypes: The evolution from clinical to molecular approaches
-
Wenzel SE. Asthma phenotypes: The evolution from clinical to molecular approaches. Nat. Med. 18(5), 716-725 (2012
-
(2012)
Nat. Med.
, vol.18
, Issue.5
, pp. 716-725
-
-
Wenzel, S.E.1
-
5
-
-
79952745551
-
Association between ormdl3 IL1RL1 and a deletion on chromosome 17q21 with asthma risk in australia
-
Ferreira MA, McRae AF, Medland SE et al. Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia. Eur. J. Hum. Genet. 19(4), 458-464 (2011
-
(2011)
Eur. J. Hum. Genet.
, vol.19
, Issue.4
, pp. 458-464
-
-
Ferreira, M.A.1
McRae, A.F.2
Medland, S.E.3
-
6
-
-
74049129976
-
Variants of DENND1B associated with asthma in children
-
Sleiman PM, Flory J, Imielinski M et al. Variants of DENND1B associated with asthma in children. N. Engl. J. Med. 362(1), 36-44 (2010
-
(2010)
N. Engl. J. Med.
, vol.362
, Issue.1
, pp. 36-44
-
-
Sleiman, P.M.1
Flory, J.2
Imielinski, M.3
-
7
-
-
77957113600
-
A large-scale, consortium-based genomewide association study of asthma
-
Moffatt MF, Gut IG, Demenais F et al. A large-scale, consortium-based genomewide association study of asthma. N. Engl. J. Med. 363(13), 1211-1221 (2010
-
(2010)
N. Engl. J. Med.
, vol.363
, Issue.13
, pp. 1211-1221
-
-
Moffatt, M.F.1
Gut, I.G.2
Demenais, F.3
-
8
-
-
61349089164
-
Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction
-
Gudbjartsson DF, Bjornsdottir US, Halapi E et al. Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction. Nat. Genet. 41(3), 342-347 (2009
-
(2009)
Nat. Genet.
, vol.41
, Issue.3
, pp. 342-347
-
-
Gudbjartsson, D.F.1
Bjornsdottir, U.S.2
Halapi, E.3
-
9
-
-
65549123032
-
Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene
-
Himes BE, Hunninghake GM, Baurley JW et al. Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene. Am. J. Hum. Genet. 84(5), 581-593 (2009
-
(2009)
Am. J. Hum. Genet.
, vol.84
, Issue.5
, pp. 581-593
-
-
Himes, B.E.1
Hunninghake, G.M.2
Baurley, J.W.3
-
10
-
-
34547216747
-
Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma
-
Moffatt MF, Kabesch M, Liang L et al. Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. Nature 448(7152), 470-473 (2007
-
(2007)
Nature
, vol.448
, Issue.7152
, pp. 470-473
-
-
Moffatt, M.F.1
Kabesch, M.2
Liang, L.3
-
11
-
-
33751087760
-
Sequence, haplotype, and association analysis of adrbeta2 in a multiethnic asthma case-control study
-
Hawkins GA, Tantisira K, Meyers DA et al. Sequence, haplotype, and association analysis of ADRbeta2 in a multiethnic asthma case-control study. Am. J. Respir. Crit. Care Med. 174(10), 1101-1109 (2006
-
(2006)
Am. J. Respir. Crit. Care Med.
, vol.174
, Issue.10
, pp. 1101-1109
-
-
Hawkins, G.A.1
Tantisira, K.2
Meyers, D.A.3
-
12
-
-
0027564307
-
Mutations in the gene encoding for the beta 2-adrenergic receptor in normal and asthmatic subjects
-
Reihsaus E, Innis M, MacIntyre N, Liggett SB. Mutations in the gene encoding for the beta 2-adrenergic receptor in normal and asthmatic subjects. Am. J. Respir. Cell Mol. Biol. 8(3), 334-339 (1993
-
(1993)
Am. J. Respir. Cell Mol. Biol.
, vol.8
, Issue.3
, pp. 334-339
-
-
Reihsaus, E.1
Innis, M.2
MacIntyre, N.3
Liggett, S.B.4
-
13
-
-
0034641736
-
Complex promoter and coding region beta 2-adrenergic receptor haplotypes alter receptor expression and predict in vivo responsiveness
-
Drysdale CM, McGraw DW, Stack CB et al. Complex promoter and coding region beta 2-adrenergic receptor haplotypes alter receptor expression and predict in vivo responsiveness. Proc. Natl Acad. Sci. USA 97(19), 10483-10488 (2000
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, Issue.19
, pp. 10483-10488
-
-
Drysdale, C.M.1
McGraw, D.W.2
Stack, C.B.3
-
14
-
-
76749084313
-
Arginase 1 and arginase 2 variations associate with asthma, asthma severity and beta2 agonist and steroid response
-
Vonk JM, Postma DS, Maarsingh H, Bruinenberg M, Koppelman GH, Meurs H. Arginase 1 and arginase 2 variations associate with asthma, asthma severity and beta2 agonist and steroid response. Pharmacogenet. Genomics 20(3), 179-186 (2010
-
(2010)
Pharmacogenet. Genomics
, vol.20
, Issue.3
, pp. 179-186
-
-
Vonk, J.M.1
Postma, D.S.2
Maarsingh, H.3
Bruinenberg, M.4
Koppelman, G.H.5
Meurs, H.6
-
15
-
-
65549167877
-
Leukotriene pathway genetics and pharmacogenetics in allergy
-
Duroudier NP, Tulah AS, Sayers I. Leukotriene pathway genetics and pharmacogenetics in allergy. Allergy 64(6), 823-839 (2009
-
(2009)
Allergy
, vol.64
, Issue.6
, pp. 823-839
-
-
Duroudier, N.P.1
Tulah, A.S.2
Sayers, I.3
-
16
-
-
0033059209
-
Pharmacogenetic association between ALOX5 promoter genotype and the response to anti-asthma treatment
-
Drazen JM, Yandava CN, Dube L et al. Pharmacogenetic association between ALOX5 promoter genotype and the response to anti-asthma treatment. Nat. Genet. 22(2), 168-170 (1999
-
(1999)
Nat. Genet.
, vol.22
, Issue.2
, pp. 168-170
-
-
Drazen, J.M.1
Yandava, C.N.2
Dube, L.3
-
17
-
-
62349095936
-
5-lipoxygenase pharmacogenetics in asthma: Overlap with Cys-leukotriene receptor antagonist loci
-
Tantisira KG, Lima J, Sylvia J, Klanderman B, Weiss ST. 5-lipoxygenase pharmacogenetics in asthma: overlap with Cys-leukotriene receptor antagonist loci. Pharmacogenet. Genomics 19(3), 244-247 (2009
-
(2009)
Pharmacogenet. Genomics
, vol.19
, Issue.3
, pp. 244-247
-
-
Tantisira, K.G.1
Lima, J.2
Sylvia, J.3
Klanderman, B.4
Weiss, S.T.5
-
18
-
-
32444440309
-
Influence of leukotriene pathway polymorphisms on response to montelukast in asthma
-
Lima JJ, Zhang S, Grant A et al. Influence of leukotriene pathway polymorphisms on response to montelukast in asthma. Am. J. Respir. Crit. Care Med. 173(4), 379-385 (2006
-
(2006)
Am. J. Respir. Crit. Care Med.
, vol.173
, Issue.4
, pp. 379-385
-
-
Lima, J.J.1
Zhang, S.2
Grant, A.3
-
19
-
-
34247561179
-
Pharmacogenetics of the 5-lipoxygenase biosynthetic pathway and variable clinical response to montelukast
-
Klotsman M, York TP, Pillai SG et al. Pharmacogenetics of the 5-lipoxygenase biosynthetic pathway and variable clinical response to montelukast. Pharmacogenet. Genomics 17(3), 189-196 (2007
-
(2007)
Pharmacogenet. Genomics
, vol.17
, Issue.3
, pp. 189-196
-
-
Klotsman, M.1
York, T.P.2
Pillai, S.G.3
-
20
-
-
3242687981
-
Corticosteroid pharmacogenetics: Association of sequence variants in CRHR1 with improved lung function in asthmatics treated with inhaled corticosteroids
-
Tantisira KG, Lake S, Silverman ES et al. Corticosteroid pharmacogenetics: Association of sequence variants in CRHR1 with improved lung function in asthmatics treated with inhaled corticosteroids. Hum. Mol. Genet. 13(13), 1353-1359 (2004
-
(2004)
Hum. Mol. Genet.
, vol.13
, Issue.13
, pp. 1353-1359
-
-
Tantisira, K.G.1
Lake, S.2
Silverman, E.S.3
-
21
-
-
77956392834
-
Dual-specificity phosphatase 1 as a pharmacogenetic modifier of inhaled steroid response among asthmatic patients
-
e1-2
-
Jin Y, Hu D, Peterson EL et al. Dual-specificity phosphatase 1 as a pharmacogenetic modifier of inhaled steroid response among asthmatic patients. J. Allergy Clin. Immunol. 126(3), 618-625.e1-2 (2010
-
(2010)
J. Allergy Clin. Immunol.
, vol.126
, Issue.3
, pp. 618-625
-
-
Jin, Y.1
Hu, D.2
Peterson, E.L.3
-
22
-
-
36749073045
-
Fcer2: A pharmacogenetic basis for severe exacerbations in children with asthma
-
Tantisira KG, Silverman ES, Mariani TJ et al. FCER2: A pharmacogenetic basis for severe exacerbations in children with asthma. J. Allergy Clin. Immunol. 120(6), 1285-1291 (2007
-
(2007)
J. Allergy Clin. Immunol.
, vol.120
, Issue.6
, pp. 1285-1291
-
-
Tantisira, K.G.1
Silverman, E.S.2
Mariani, T.J.3
-
23
-
-
82955171585
-
FCER2 T2206C variant associated with chronic symptoms and exacerbations in steroid-treated asthmatic children
-
Koster ES, Maitland-van der Zee AH, Tavendale R et al. FCER2 T2206C variant associated with chronic symptoms and exacerbations in steroid-treated asthmatic children. Allergy 66(12), 1546-1552 (2011
-
(2011)
Allergy
, vol.66
, Issue.12
, pp. 1546-1552
-
-
Koster, E.S.1
Maitland-Van Der Zee, A.H.2
Tavendale, R.3
-
24
-
-
80053370268
-
Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma
-
Tantisira KG, Lasky-Su J, Harada M et al. Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma. N. Engl. J. Med. 365(13), 1173-1183 (2011
-
(2011)
N. Engl. J. Med.
, vol.365
, Issue.13
, pp. 1173-1183
-
-
Tantisira, K.G.1
Lasky-Su, J.2
Harada, M.3
-
25
-
-
67650150137
-
Genetic variants of GSNOR and ADRB2 influence response to albuterol in African-American children with severe asthma
-
Moore PE, Ryckman KK, Williams SM, Patel N, Summar ML, Sheller Jr. Genetic variants of GSNOR and ADRB2 influence response to albuterol in African-American children with severe asthma. Pediatr. Pulmonol. 44(7), 649-654 (2009
-
(2009)
Pediatr. Pulmonol.
, vol.44
, Issue.7
, pp. 649-654
-
-
Moore, P.E.1
Ryckman, K.K.2
Williams, S.M.3
Patel, N.4
Summar, M.L.5
Sheller, J.R.6
-
26
-
-
0033803781
-
Variant ltc (4) synthase allele modifies cysteinyl leukotriene synthesis in eosinophils and predicts clinical response to zafirlukast
-
Sampson AP, Siddiqui S, Buchanan D et al. Variant LTC(4) synthase allele modifies cysteinyl leukotriene synthesis in eosinophils and predicts clinical response to zafirlukast. Thorax 55(Suppl. 2), S28-S31 (2000
-
(2000)
Thorax
, vol.55
, Issue.SUPPL. 2
-
-
Sampson, A.P.1
Siddiqui, S.2
Buchanan, D.3
-
27
-
-
18644372214
-
Leukotriene C4 synthase gene A(-444)C polymorphism and clinical response to a CYS-LT(1) antagonist, pranlukast, in Japanese patients with moderate asthma
-
Asano K, Shiomi T, Hasegawa N et al. Leukotriene C4 synthase gene A(-444)C polymorphism and clinical response to a CYS-LT(1) antagonist, pranlukast, in Japanese patients with moderate asthma. Pharmacogenetics 12(7), 565-570 (2002
-
(2002)
Pharmacogenetics
, vol.12
, Issue.7
, pp. 565-570
-
-
Asano, K.1
Shiomi, T.2
Hasegawa, N.3
-
28
-
-
0036906640
-
Clinical and genetic features underlying the response of patients with bronchial asthma to treatment with a leukotriene receptor antagonist
-
Mastalerz L, Nizankowska E, Sanak M et al. Clinical and genetic features underlying the response of patients with bronchial asthma to treatment with a leukotriene receptor antagonist. Eur. J. Clin. Invest. 32(12), 949-955 (2002
-
(2002)
Eur. J. Clin. Invest.
, vol.32
, Issue.12
, pp. 949-955
-
-
Mastalerz, L.1
Nizankowska, E.2
Sanak, M.3
-
29
-
-
0142031051
-
Effect of montelukast on time-course of exhaled nitric oxide in asthma: Influence of LTC4 synthase A(-444)C polymorphism
-
Whelan GJ, Blake K, Kissoon N et al. Effect of montelukast on time-course of exhaled nitric oxide in asthma: Influence of LTC4 synthase A(-444)C polymorphism. Pediatr. Pulmonol. 36(5), 413-420 (2003
-
(2003)
Pediatr. Pulmonol.
, vol.36
, Issue.5
, pp. 413-420
-
-
Whelan, G.J.1
Blake, K.2
Kissoon, N.3
-
30
-
-
34147189140
-
Treatment heterogeneity in asthma: Genetics of response to leukotriene modifiers
-
Lima JJ. Treatment heterogeneity in asthma: Genetics of response to leukotriene modifiers. Mol. Diagn. Ther. 11(2), 97-104 (2007
-
(2007)
Mol. Diagn. Ther.
, vol.11
, Issue.2
, pp. 97-104
-
-
Lima, J.J.1
-
31
-
-
70450193494
-
Pharmacogenetic study of the effects of NK2R G231E G>A and TBX21 H33Q C>G polymorphisms on asthma control with inhaled corticosteroid treatment
-
Ye YM, Lee HY, Kim SH et al. Pharmacogenetic study of the effects of NK2R G231E G>A and TBX21 H33Q C>G polymorphisms on asthma control with inhaled corticosteroid treatment. J. Clin. Pharm. Ther. 34(6), 693-701 (2009
-
(2009)
J. Clin. Pharm. Ther.
, vol.34
, Issue.6
, pp. 693-701
-
-
Ye, Y.M.1
Lee, H.Y.2
Kim, S.H.3
-
32
-
-
59549106159
-
Absorption of montelukast is transporter mediated: A common variant of OATP2B1 is associated with reduced plasma concentrations and poor response
-
Mougey EB, Feng H, Castro M, Irvin CG, Lima JJ. Absorption of montelukast is transporter mediated: A common variant of OATP2B1 is associated with reduced plasma concentrations and poor response. Pharmacogenet. Genomics 19(2), 129-138 (2009
-
(2009)
Pharmacogenet. Genomics
, vol.19
, Issue.2
, pp. 129-138
-
-
Mougey, E.B.1
Feng, H.2
Castro, M.3
Irvin, C.G.4
Lima, J.J.5
-
33
-
-
67649210692
-
The glucocorticoid receptor heterocomplex gene STIP1 is associated with improved lung function in asthmatic subjects treated with inhaled corticosteroids
-
e7
-
Hawkins GA, Lazarus R, Smith RS et al. The glucocorticoid receptor heterocomplex gene STIP1 is associated with improved lung function in asthmatic subjects treated with inhaled corticosteroids. J. Allergy Clin. Immunol. 123(6), 1376-1383.e7 (2009
-
(2009)
J. Allergy Clin. Immunol.
, vol.123
, Issue.6
, pp. 1376-1383
-
-
Hawkins, G.A.1
Lazarus, R.2
Smith, R.S.3
-
34
-
-
77952557918
-
Missing heritability and strategies for finding the underlying causes of complex disease
-
Eichler EE, Flint J, Gibson G et al. Missing heritability and strategies for finding the underlying causes of complex disease. Nat. Rev. Genet. 11(6), 446-450 (2010
-
(2010)
Nat. Rev. Genet.
, vol.11
, Issue.6
, pp. 446-450
-
-
Eichler, E.E.1
Flint, J.2
Gibson, G.3
-
35
-
-
79952048799
-
Genetics systems genetics
-
Nadeau JH, Dudley AM. Genetics. Systems genetics. Science 331(6020), 1015-1016 (2011
-
(2011)
Science
, vol.331
, Issue.6020
, pp. 1015-1016
-
-
Nadeau, J.H.1
Dudley, A.M.2
-
36
-
-
69049118114
-
Systems biology in pharmacogenomic research: The way to personalized prescribing?
-
Koster ES, Rodin AS, Raaijmakers JA, Maitland-van der Zee AH. Systems biology in pharmacogenomic research: The way to personalized prescribing? Pharmacogenomics 10(6), 971-981 (2009
-
(2009)
Pharmacogenomics
, vol.10
, Issue.6
, pp. 971-981
-
-
Koster, E.S.1
Rodin, A.S.2
Raaijmakers, J.A.3
Maitland-Van Der Zee, A.H.4
-
37
-
-
80052932702
-
Systems biology data analysis methodology in pharmacogenomics
-
Rodin AS, Gogoshin G, Boerwinkle E. Systems biology data analysis methodology in pharmacogenomics. Pharmacogenomics 12(9), 1349-1360 (2011
-
(2011)
Pharmacogenomics
, vol.12
, Issue.9
, pp. 1349-1360
-
-
Rodin, A.S.1
Gogoshin, G.2
Boerwinkle, E.3
-
39
-
-
0033012176
-
-
The Childhood Asthma Management Program (CAMP): Design, rationale, and methods Childhood Asthma Management Program Research Group
-
The Childhood Asthma Management Program (CAMP): Design, rationale, and methods. Childhood Asthma Management Program Research Group. Control. Clin. Trials 20(1), 91-120 (1999
-
(1999)
Control. Clin. Trials
, vol.20
, Issue.1
, pp. 91-120
-
-
-
40
-
-
0034642066
-
-
Long-term effects of budesonide or nedocromil in children with asthma. The Childhood Asthma Management Program Research Group
-
Long-term effects of budesonide or nedocromil in children with asthma. The Childhood Asthma Management Program Research Group. N. Engl. J. Med. 343(15), 1054-1063 (2000
-
(2000)
N. Engl. J. Med.
, vol.343
, Issue.15
, pp. 1054-1063
-
-
-
41
-
-
0035938606
-
Long-acting beta2-agonist monotherapy vs continued therapy with inhaled corticosteroids in patients with persistent asthma: A randomized controlled trial
-
Lazarus SC, Boushey HA, Fahy JV et al. Long-acting beta2-agonist monotherapy vs continued therapy with inhaled corticosteroids in patients with persistent asthma: A randomized controlled trial. JAMA 285(20), 2583-2593 (2001
-
(2001)
JAMA
, vol.285
, Issue.20
, pp. 2583-2593
-
-
Lazarus, S.C.1
Boushey, H.A.2
Fahy, J.V.3
-
42
-
-
0342419450
-
Inhaled corticosteroid reduction and elimination in patients with persistent asthma receiving salmeterol: A randomized controlled trial
-
Lemanske RF Jr, Sorkness CA, Mauger EA et al. Inhaled corticosteroid reduction and elimination in patients with persistent asthma receiving salmeterol: A randomized controlled trial. JAMA 285(20), 2594-2603 (2001
-
(2001)
JAMA
, vol.285
, Issue.20
, pp. 2594-2603
-
-
Lemanske Jr., R.F.1
Sorkness, C.A.2
Mauger, E.A.3
-
43
-
-
0034007863
-
Multicentre, randomised, parallel-group study of the efficacy and tolerability of flunisolide administered once daily via aerochamber in the treatment of mild to moderate asthma
-
Bielory L, Picone F, Rabinowitz P et al. Multicentre, randomised, parallel-group study of the efficacy and tolerability of flunisolide administered once daily via AeroChamber in the treatment of mild to moderate asthma. Clin. Drug Investig. 19, 93-101 (2000
-
(2000)
Clin. Drug Investig.
, vol.19
, pp. 93-101
-
-
Bielory, L.1
Picone, F.2
Rabinowitz, P.3
-
44
-
-
34249081246
-
Randomized comparison of strategies for reducing treatment in mild persistent asthma
-
Peters S, Anthonisen N, Castro M et al. Randomized comparison of strategies for reducing treatment in mild persistent asthma. N. Engl. J. Med. 356, 2027-2039 (2007
-
(2007)
N. Engl. J. Med.
, vol.356
, pp. 2027-2039
-
-
Peters, S.1
Anthonisen, N.2
Castro, M.3
-
45
-
-
22844449221
-
Genomic screening and replication using the same data set in family-based association testing
-
Van Steen K, McQueen MB, Herbert A et al. Genomic screening and replication using the same data set in family-based association testing. Nat. Genet. 37(7), 683-691 (2005
-
(2005)
Nat. Genet.
, vol.37
, Issue.7
, pp. 683-691
-
-
Van Steen, K.1
McQueen, M.B.2
Herbert, A.3
-
46
-
-
0345257865
-
A new powerful non-parametric two-stage approach for testing multiple phenotypes in family-based association studies
-
Lange C, Lyon H, DeMeo D, Raby B, Silverman EK, Weiss ST. A new powerful non-parametric two-stage approach for testing multiple phenotypes in family-based association studies. Hum. Hered. 56(1-3), 10-17 (2003
-
(2003)
Hum. Hered.
, vol.56
, Issue.1-3
, pp. 10-17
-
-
Lange, C.1
Lyon, H.2
DeMeo, D.3
Raby, B.4
Silverman, E.K.5
Weiss, S.T.6
-
47
-
-
6944232728
-
Use of regularly scheduled albuterol treatment in asthma: Genotype-stratified, randomised, placebo-controlled cross-over trial
-
Israel E, Chinchilli VM, Ford JG et al. Use of regularly scheduled albuterol treatment in asthma: Genotype-stratified, randomised, placebo-controlled cross-over trial. Lancet 364(9444), 1505-1512 (2004
-
(2004)
Lancet
, vol.364
, Issue.9444
, pp. 1505-1512
-
-
Israel, E.1
Chinchilli, V.M.2
Ford, J.G.3
-
48
-
-
19944427616
-
TBX21: A functional variant predicts improvement in asthma with the use of inhaled corticosteroids
-
Tantisira KG, Hwang ES, Raby BA et al. TBX21: A functional variant predicts improvement in asthma with the use of inhaled corticosteroids. Proc. Natl Acad. Sci. USA 101(52), 18099-18104 (2004
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, Issue.52
, pp. 18099-18104
-
-
Tantisira, K.G.1
Hwang, E.S.2
Raby, B.A.3
-
49
-
-
79951825578
-
Regulatory haplotypes in ARG1 are associated with altered bronchodilator response
-
Duan QL, Gaume BR, Hawkins GA et al. Regulatory haplotypes in ARG1 are associated with altered bronchodilator response. Am. J. Respir. Crit. Care Med. 183(4), 449-454 (2011
-
(2011)
Am. J. Respir. Crit. Care Med.
, vol.183
, pp. 449-454
-
-
Duan, Q.L.1
Gaume, B.R.2
Hawkins, G.A.3
-
50
-
-
81755165915
-
The pharmacogenetics and pharmacogenomics of asthma therapy
-
Tse SM, Tantisira K, Weiss ST. The pharmacogenetics and pharmacogenomics of asthma therapy. Pharmacogenomics J. 11(6), 383-392 (2011
-
(2011)
Pharmacogenomics J.
, vol.11
, Issue.6
, pp. 383-392
-
-
Tse, S.M.1
Tantisira, K.2
Weiss, S.T.3
-
51
-
-
69149086152
-
The pharmacogenetics of asthma treatment
-
Tantisira K, Weiss S. The pharmacogenetics of asthma treatment. Curr. Allergy Asthma Rep. 9(1), 10-17 (2009
-
(2009)
Curr. Allergy Asthma Rep.
, vol.9
, Issue.1
, pp. 10-17
-
-
Tantisira, K.1
Weiss, S.2
-
52
-
-
58149296390
-
Pharmacogenetics of asthma
-
Lima JJ, Blake KV, Tantisira KG, Weiss ST. Pharmacogenetics of asthma. Curr. Opin. Pulm. Med. 15(1), 57-62 (2009
-
(2009)
Curr. Opin. Pulm. Med.
, vol.15
, Issue.1
, pp. 57-62
-
-
Lima, J.J.1
Blake, K.V.2
Tantisira, K.G.3
Weiss, S.T.4
-
53
-
-
33746842930
-
Overview of the pharmacogenetics of asthma treatment
-
Weiss ST, Litonjua AA, Lange C et al. Overview of the pharmacogenetics of asthma treatment. Pharmacogenomics J. 6(5), 311-326 (2006
-
(2006)
Pharmacogenomics J
, vol.6
, Issue.5
, pp. 311-326
-
-
Weiss, S.T.1
Litonjua, A.A.2
Lange, C.3
-
54
-
-
20344374952
-
The pharmacogenetics of asthma: An update
-
Tantisira KG, Weiss ST. The pharmacogenetics of asthma: An update. Curr. Opin. Mol. Ther. 7(3), 209-217 (2005
-
(2005)
Curr. Opin. Mol. Ther.
, vol.7
, Issue.3
, pp. 209-217
-
-
Tantisira, K.G.1
Weiss, S.T.2
-
55
-
-
79551619357
-
Pharmacogenetics of beta2 adrenergic receptor gene polymorphisms, long-acting beta-agonists and asthma
-
Chung LP, Waterer G, Thompson PJ. Pharmacogenetics of beta2 adrenergic receptor gene polymorphisms, long-acting beta-agonists and asthma. Clin. Exp. Allergy 41(3), 312-326 (2011
-
(2011)
Clin. Exp. Allergy
, vol.41
, Issue.3
, pp. 312-326
-
-
Chung, L.P.1
Waterer, G.2
Thompson, P.J.3
-
56
-
-
24944564606
-
Bronchodilator response in relation to beta2-adrenoceptor haplotype in patients with asthma
-
Taylor DR, Epton MJ, Kennedy MA et al. Bronchodilator response in relation to beta2-adrenoceptor haplotype in patients with asthma. Am. J. Respir. Crit. Care Med. 172(6), 700-703 (2005
-
(2005)
Am. J. Respir. Crit. Care Med.
, vol.172
, Issue.6
, pp. 700-703
-
-
Taylor, D.R.1
Epton, M.J.2
Kennedy, M.A.3
-
57
-
-
0027417365
-
Reported asthma among puerto rican, mexican- american, and cuban children, 1982 through 1984
-
Carter-Pokras OD, Gergen PJ. Reported asthma among Puerto Rican, Mexican- American, and Cuban children, 1982 through 1984. Am. J. Public Health 83(4), 580-582 (1993
-
(1993)
Am. J. Public Health
, vol.83
, Issue.4
, pp. 580-582
-
-
Carter-Pokras, O.D.1
Gergen, P.J.2
-
58
-
-
0034011530
-
-
Asthma Mortality In U.S Hispanics of Mexican Puerto Rican And Cuban Heritage 1990-1995 Pt 1
-
Homa DM, Mannino DM, Lara M. Asthma mortality in U.S. Hispanics of Mexican, Puerto Rican, and Cuban heritage, 1990-1995. Am. J. Respir. Crit. Care Med. 161(2 Pt 1), 504-509 (2000
-
(2000)
Am. J. Respir. Crit. Care Med.
, vol.161
, Issue.2
, pp. 504-509
-
-
Homa, D.M.1
Mannino, D.M.2
Lara, M.3
-
59
-
-
20144363204
-
Pharmacogenetic differences in response to albuterol between puerto ricans and mexicans with asthma
-
Choudhry S, Ung N, Avila PC et al. Pharmacogenetic differences in response to albuterol between Puerto Ricans and Mexicans with asthma. Am. J. Respir. Crit. Care Med. 171(6), 563-570 (2005
-
(2005)
Am. J. Respir. Crit. Care Med.
, vol.171
, Issue.6
, pp. 563-570
-
-
Choudhry, S.1
Ung, N.2
Avila, P.C.3
-
60
-
-
82255162755
-
Pharmacogenomics of beta-adrenergic receptor physiology and response to beta-blockade
-
von Homeyer P, Schwinn DA. Pharmacogenomics of beta-adrenergic receptor physiology and response to beta-blockade. Anesth. Analg. 113(6), 1305-1318 (2011
-
(2011)
Anesth. Analg.
, vol.113
, Issue.6
, pp. 1305-1318
-
-
Von Homeyer, P.1
Schwinn, D.A.2
-
61
-
-
78650444965
-
Influence of gene-gene interactions on response to albuterol therapy
-
Moore PE. Influence of gene-gene interactions on response to albuterol therapy. Pharmacogenomics 12(1), 1-3 (2011
-
(2011)
Pharmacogenomics
, vol.12
, Issue.1
, pp. 1-3
-
-
Moore, P.E.1
-
62
-
-
21244503821
-
Molecular properties and pharmacogenetics of a polymorphism of adenylyl cyclase type 9 in asthma: Interaction between beta-agonist and corticosteroid pathways
-
Tantisira KG, Small KM, Litonjua AA, Weiss ST, Liggett SB. Molecular properties and pharmacogenetics of a polymorphism of adenylyl cyclase type 9 in asthma: Interaction between beta-agonist and corticosteroid pathways. Hum. Mol. Genet. 14(12), 1671-1677 (2005
-
(2005)
Hum. Mol. Genet.
, vol.14
, Issue.12
, pp. 1671-1677
-
-
Tantisira, K.G.1
Small, K.M.2
Litonjua, A.A.3
Weiss, S.T.4
Liggett, S.B.5
-
63
-
-
79955779009
-
Combined pharmacogenetic effect of ADCY9 and ADRB2 gene polymorphisms on the bronchodilator response to inhaled combination therapy
-
Kim SH, Ye YM, Lee HY, Sin HJ, Park HS. Combined pharmacogenetic effect of ADCY9 and ADRB2 gene polymorphisms on the bronchodilator response to inhaled combination therapy. J. Clin. Pharm. Ther. 36(3), 399-405 (2011
-
(2011)
J. Clin. Pharm. Ther.
, vol.36
, Issue.3
, pp. 399-405
-
-
Kim, S.H.1
Ye, Y.M.2
Lee, H.Y.3
Sin, H.J.4
Park, H.S.5
-
64
-
-
77952422367
-
Gsno reductase and beta2-adrenergic receptor gene-gene interaction: Bronchodilator responsiveness to albuterol
-
Choudhry S, Que LG, Yang Z et al. GSNO reductase and beta2-adrenergic receptor gene-gene interaction: Bronchodilator responsiveness to albuterol. Pharmacogenet. Genomics 20(6), 351-358 (2010
-
(2010)
Pharmacogenet. Genomics
, vol.20
, Issue.6
, pp. 351-358
-
-
Choudhry, S.1
Que, L.G.2
Yang, Z.3
-
65
-
-
34748901203
-
The relationship between polymorphisms in the glutamate cysteine ligase gene and asthma susceptibility
-
Polonikov AV, Ivanov VP, Solodilova MA, Khoroshaya IV, Kozhuhov MA, Panfilov VI. The relationship between polymorphisms in the glutamate cysteine ligase gene and asthma susceptibility. Respir. Med. 101(11), 2422-2424 (2007
-
(2007)
Respir. Med.
, vol.101
, Issue.11
, pp. 2422-2424
-
-
Polonikov, A.V.1
Ivanov, V.P.2
Solodilova, M.A.3
Khoroshaya, I.V.4
Kozhuhov, M.A.5
Panfilov, V.I.6
-
66
-
-
84884211479
-
A polymorphism in the thyroid hormone receptor gene is associated with bronchodilator response in asthmatics
-
doi:10.1038/tpj.2011.56. Epub ahead of print
-
Duan QL, Du R, Lasky-Su J et al. A polymorphism in the thyroid hormone receptor gene is associated with bronchodilator response in asthmatics. Pharmacogenomics J. doi:10.1038/tpj.2011.56. (2012) (Epub ahead of print
-
(2012)
Pharmacogenomics J.
-
-
Duan, Q.L.1
Du, R.2
Lasky-Su, J.3
-
67
-
-
51849107399
-
Arginase inhibition protects against allergen-induced airway obstruction, hyperresponsiveness, and inflammation
-
Maarsingh H, Zuidhof AB, Bos IS et al. Arginase inhibition protects against allergen-induced airway obstruction, hyperresponsiveness, and inflammation. Am. J. Respir. Crit. Care Med. 178(6), 565-573 (2008
-
(2008)
Am. J. Respir. Crit. Care Med.
, vol.178
, Issue.6
, pp. 565-573
-
-
Maarsingh, H.1
Zuidhof, A.B.2
Bos, I.S.3
-
68
-
-
0036016110
-
Increased arginase activity underlies allergen-induced deficiency of cNOS-derived nitric oxide and airway hyperresponsiveness
-
Meurs H, McKay S, Maarsingh H et al. Increased arginase activity underlies allergen-induced deficiency of cNOS-derived nitric oxide and airway hyperresponsiveness. Br. J. Pharmacol. 136(3), 391-398 (2002
-
(2002)
Br. J. Pharmacol.
, vol.136
, Issue.3
, pp. 391-398
-
-
Meurs, H.1
McKay, S.2
Maarsingh, H.3
-
69
-
-
70449628095
-
Pharmacogenetics of asthma therapy
-
Duan QL, Tantisira KG. Pharmacogenetics of asthma therapy. Curr. Pharm. Des. 15(32), 3742-3753 (2009
-
(2009)
Curr. Pharm. Des.
, vol.15
, Issue.32
, pp. 3742-3753
-
-
Duan, Q.L.1
Tantisira, K.G.2
-
70
-
-
69349086363
-
Genetics and pharmacogenetics of the leukotriene pathway
-
Tantisira KG, Drazen JM. Genetics and pharmacogenetics of the leukotriene pathway. J. Allergy Clin. Immunol. 124(3), 422-427 (2009
-
(2009)
J. Allergy Clin. Immunol.
, vol.124
, Issue.3
, pp. 422-427
-
-
Tantisira, K.G.1
Drazen, J.M.2
-
71
-
-
66949160382
-
Asthma pharmacogenetic study using finite mixture models to handle drug-response heterogeneity
-
York TP, Vargas-Irwin C, Anderson WH, van den Oord EJ. Asthma pharmacogenetic study using finite mixture models to handle drug-response heterogeneity. Pharmacogenomics 10(5), 753-767 (2009
-
(2009)
Pharmacogenomics
, vol.10
, Issue.5
, pp. 753-767
-
-
York, T.P.1
Vargas Irwin, C.2
Anderson, W.H.3
Van Den Oord, E.J.4
-
72
-
-
84856350609
-
Influence of leukotriene pathway polymorphisms on clinical responses to montelukast in Japanese patients with asthma
-
Kotani H, Kishi R, Mouri A et al. Influence of leukotriene pathway polymorphisms on clinical responses to montelukast in Japanese patients with asthma. J. Clin. Pharm. Ther. 37(1), 112-116 (2012
-
(2012)
J. Clin. Pharm. Ther.
, vol.37
, Issue.1
, pp. 112-116
-
-
Kotani, H.1
Kishi, R.2
Mouri, A.3
-
73
-
-
77949376205
-
The role of LTA4H and ALOX5AP genes in the risk for asthma in Latinos
-
Via M, De Giacomo A, Corvol H et al. The role of LTA4H and ALOX5AP genes in the risk for asthma in Latinos. Clin. Exp. Allergy 40(4), 582-589 (2010
-
(2010)
Clin. Exp. Allergy
, vol.40
, Issue.4
, pp. 582-589
-
-
Via, M.1
De Giacomo, A.2
Corvol, H.3
-
74
-
-
77957781747
-
ALOX5AP and LTA4H polymorphisms modify augmentation of bronchodilator responsiveness by leukotriene modifiers in latinos
-
Tcheurekdjian H, Via M, De Giacomo A et al. ALOX5AP and LTA4H polymorphisms modify augmentation of bronchodilator responsiveness by leukotriene modifiers in Latinos. J. Allergy Clin. Immunol. 126(4), 853-858 (2010
-
(2010)
J. Allergy Clin. Immunol.
, vol.126
, Issue.4
, pp. 853-858
-
-
Tcheurekdjian, H.1
Via, M.2
De Giacomo, A.3
-
75
-
-
0038241502
-
Variations of the human glucocorticoid receptor gene (NR3C1): Pathological and in vitro mutations and polymorphisms
-
Bray PJ, Cotton RG. Variations of the human glucocorticoid receptor gene (NR3C1): Pathological and in vitro mutations and polymorphisms. Hum. Mutat. 21(6), 557-568 (2003
-
(2003)
Hum. Mutat.
, vol.21
, Issue.6
, pp. 557-568
-
-
Bray, P.J.1
Cotton, R.G.2
-
76
-
-
3142695470
-
Identification of polymorphisms in the human glucocorticoid receptor gene (NR3C1) in a multi-racial asthma case and control screening panel
-
Hawkins GA, Amelung PJ, Smith RS et al. Identification of polymorphisms in the human glucocorticoid receptor gene (NR3C1) in a multi-racial asthma case and control screening panel. DNA Seq. 15(3), 167-173 (2004
-
(2004)
DNA Seq
, vol.15
, Issue.3
, pp. 167-173
-
-
Hawkins, G.A.1
Amelung, P.J.2
Smith, R.S.3
-
77
-
-
80052448224
-
The Bcl I single nucleotide polymorphism of the human glucocorticoid receptor gene h-GR/NR3C1 promoter in patients with bronchial asthma: Pilot study
-
Pietras T, Panek M, Tworek D et al. The Bcl I single nucleotide polymorphism of the human glucocorticoid receptor gene h-GR/NR3C1 promoter in patients with bronchial asthma: Pilot study. Mol. Biol. Rep. 38(6), 3953-3958 (2011
-
(2011)
Mol. Biol. Rep.
, vol.38
, Issue.6
, pp. 3953-3958
-
-
Pietras, T.1
Panek, M.2
Tworek, D.3
-
78
-
-
84863094859
-
The role of functional single nucleotide polymorphisms of the human glucocorticoid receptor gene NR3C1 in Polish patients with bronchial asthma
-
Panek M, Pietras T, Antczak A, Gorski P, Kuna P, Szemraj J. The role of functional single nucleotide polymorphisms of the human glucocorticoid receptor gene NR3C1 in Polish patients with bronchial asthma. Mol. Biol. Rep. 39(4), 4749-4757 (2011
-
(2011)
Mol. Biol. Rep.
, vol.39
, Issue.4
, pp. 4749-4757
-
-
Panek, M.1
Pietras, T.2
Antczak, A.3
Gorski, P.4
Kuna, P.5
Szemraj, J.6
-
79
-
-
14744293163
-
Pharmacogenetic approaches in the treatment of asthma
-
Sayers I, Hall IP. Pharmacogenetic approaches in the treatment of asthma. Curr. Allergy Asthma Rep. 5(2), 101-108 (2005
-
(2005)
Curr. Allergy Asthma Rep.
, vol.5
, Issue.2
, pp. 101-108
-
-
Sayers, I.1
Hall, I.P.2
-
80
-
-
77953303583
-
An integrative systems biology approach to understanding pulmonary diseases
-
Auffray C, Adcock IM, Chung KF, Djukanovic R, Pison C, Sterk PJ. An integrative systems biology approach to understanding pulmonary diseases. Chest 137(6), 1410-1416 (2010
-
(2010)
Chest
, vol.137
, Issue.6
, pp. 1410-1416
-
-
Auffray, C.1
Adcock, I.M.2
Chung, K.F.3
Djukanovic, R.4
Pison, C.5
Sterk, P.J.6
-
83
-
-
0035478854
-
Random forests
-
Brieman L. Random Forests. Mach. Learn. 45(1), 5-32 (2001
-
(2001)
Mach. Learn.
, vol.45
, Issue.1
, pp. 5-32
-
-
Brieman, L.1
-
86
-
-
25144441907
-
Mining genetic epidemiology data with Bayesian networks I: Bayesian networks and example application (plasma apoE levels
-
Rodin AS, Boerwinkle E. Mining genetic epidemiology data with Bayesian networks I: Bayesian networks and example application (plasma apoE levels). Bioinformatics 21(15), 3273-3278 (2005
-
(2005)
Bioinformatics
, vol.21
, Issue.15
, pp. 3273-3278
-
-
Rodin, A.S.1
Boerwinkle, E.2
-
87
-
-
34548459831
-
A primer on learning in Bayesian networks for computational biology
-
Needham CJ, Bradford JR, Bulpitt AJ, Westhead DR. A primer on learning in Bayesian networks for computational biology. PLoS Comput. Biol. 3(8), e129 (2007
-
(2007)
Plos Comput. Biol.
, vol.3
, Issue.8
-
-
Needham, C.J.1
Bradford, J.R.2
Bulpitt, A.J.3
Westhead, D.R.4
-
88
-
-
1642306366
-
On the use of Bayesian networks to analyse survey data
-
Sebastiani P, Ramoni M. On the use of Bayesian networks to analyse survey data. Res Off. Statist. 41(1), 53-64 (2001
-
(2001)
Res Off. Statist.
, vol.41
, Issue.1
, pp. 53-64
-
-
Sebastiani, P.1
Ramoni, M.2
-
89
-
-
84866441569
-
-
Intelligent Data Analysis: An Introduction. Hand DJ, Berthold MR (Eds). Springer, NY, USA
-
Ramoni M, Sebastiani P. Bayesian methods: Intelligent data analysis. In: Intelligent Data Analysis: An Introduction. Hand DJ, Berthold MR (Eds). Springer, NY, USA, 128-166 (2003
-
(2003)
Bayesian Methods: Intelligent Data Analysis
, pp. 128-166
-
-
Ramoni, M.1
Sebastiani, P.2
-
90
-
-
84861334467
-
Association of variants in innate immune genes with asthma and eczema
-
Sharma S, Poon A, Himes BE et al. Association of variants in innate immune genes with asthma and eczema. Pediatr. Allergy Immunol. 23(4), 315-323 (2011
-
(2011)
Pediatr. Allergy Immunol.
, vol.23
, Issue.4
, pp. 315-323
-
-
Sharma, S.1
Poon, A.2
Himes, B.E.3
-
91
-
-
65349143362
-
Prediction of chronic obstructive pulmonary disease (COPD) in asthma patients using electronic medical records
-
Himes BE, Dai Y, Kohane IS, Weiss ST, Ramoni MF. Prediction of chronic obstructive pulmonary disease (COPD) in asthma patients using electronic medical records. J. Am. Med. Inform. Assoc. 16(3), 371-379 (2009
-
(2009)
J. Am. Med. Inform. Assoc.
, vol.16
, Issue.3
, pp. 371-379
-
-
Himes, B.E.1
Dai, Y.2
Kohane, I.S.3
Weiss, S.T.4
Ramoni, M.F.5
-
92
-
-
34748862918
-
Prospective evaluation of a Bayesian Network for detecting asthma exacerbations in a pediatric emergency department
-
Sanders DL, Aronsky D. Prospective evaluation of a Bayesian Network for detecting asthma exacerbations in a Pediatric Emergency Department. AMIA. Annu. Symp. Proc. 1085 (2006
-
(2006)
AMIA. Annu. Symp. Proc
, vol.1085
-
-
Sanders, D.L.1
Aronsky, D.2
-
93
-
-
34748831018
-
Detecting asthma exacerbations in a pediatric emergency department using a Bayesian network
-
Sanders DL, Aronsky D. Detecting asthma exacerbations in a pediatric emergency department using a Bayesian network. AMIA. Annu. Symp. Proc. 684-688 (2006
-
(2006)
AMIA. Annu. Symp. Proc.
, pp. 684-688
-
-
Sanders, D.L.1
Aronsky, D.2
-
94
-
-
70649105577
-
Predicting response to short-acting bronchodilator medication using Bayesian networks
-
Himes BE, Wu AC, Duan QL et al. Predicting response to short-acting bronchodilator medication using Bayesian networks. Pharmacogenomics 10(9), 1393-1412 (2009
-
(2009)
Pharmacogenomics
, vol.10
, Issue.9
, pp. 1393-1412
-
-
Himes, B.E.1
Wu, A.C.2
Duan, Q.L.3
-
95
-
-
75149176440
-
Klos Ket al. Use of wrapper algorithms coupled with a random forests classifier for variable selection in large-scale genomic association studies
-
Rodin AS, Litvinenko A, Klos Ket al. Use of wrapper algorithms coupled with a random forests classifier for variable selection in large-scale genomic association studies. J. Comput. Biol. 16(12), 1705-1718 (2009
-
(2009)
J. Comput. Biol.
, vol.16
, Issue.12
, pp. 1705-1718
-
-
Rodin, A.S.1
Litvinenko, A.2
-
96
-
-
77953351710
-
An application of Random Forests to a genome-wide association dataset: Methodological considerations and new findings
-
Goldstein BA, Hubbard AE, Cutler A, Barcellos LF. An application of Random Forests to a genome-wide association dataset: Methodological considerations and new findings. BMC Genet. 11, 49 (2010
-
(2010)
BMC Genet
, vol.11
, pp. 49
-
-
Goldstein, B.A.1
Hubbard, A.E.2
Cutler, A.3
Barcellos, L.F.4
-
97
-
-
58149343568
-
Application of two machine learning algorithms to genetic association studies in the presence of covariates
-
Nonyane BA, Foulkes AS. Application of two machine learning algorithms to genetic association studies in the presence of covariates. BMC Genet. 9, 71 (2008
-
(2008)
BMC Genet
, vol.9
, pp. 71
-
-
Nonyane, B.A.1
Foulkes, A.S.2
-
98
-
-
77958469133
-
Multigenic modeling of complex disease by random forests
-
Sun YV. Multigenic modeling of complex disease by random forests. Adv. Genet. 72, 73-99 (2010
-
(2010)
Adv. Genet.
, vol.72
, pp. 73-99
-
-
Sun, Y.V.1
-
99
-
-
12744259874
-
Falls Ket al. Identifying SNPs predictive of phenotype using random forests
-
Bureau A, Dupuis J, Falls Ket al. Identifying SNPs predictive of phenotype using random forests. Genet. Epidemiol. 28(2), 171-182 (2005
-
(2005)
Genet. Epidemiol.
, vol.28
, Issue.2
, pp. 171-182
-
-
Bureau, A.1
Dupuis, J.2
-
100
-
-
77957157531
-
A screening methodology based on random forests to improve the detection of gene-gene interactions
-
De Lobel L, Geurts P, Baele G, Castro-Giner F, Kogevinas M, Van Steen K. A screening methodology based on Random Forests to improve the detection of gene-gene interactions. Eur. J. Hum. Genet. 18(10), 1127-1132 (2010
-
(2010)
Eur. J. Hum. Genet.
, vol.18
, Issue.10
, pp. 1127-1132
-
-
De Lobel, L.1
Geurts, P.2
Baele, G.3
Castro-Giner, F.4
Kogevinas, M.5
Van Steen, K.6
-
101
-
-
79959682373
-
Genome Wide Association Study to predict severe asthma exacerbations in children using random forests classifiers
-
Xu M, Tantisira KG, Wu A et al. Genome Wide Association Study to predict severe asthma exacerbations in children using random forests classifiers. BMC Med. Genet. 12, 90 (2011
-
(2011)
BMC Med. Genet.
, vol.12
, pp. 90
-
-
Xu, M.1
Tantisira, K.G.2
Wu, A.3
-
103
-
-
1542604092
-
Genomic approaches in dissecting complex biological pathways
-
Sun N, Zhao H. Genomic approaches in dissecting complex biological pathways. Pharmacogenomics 5(2), 163-179 (2004
-
(2004)
Pharmacogenomics
, vol.5
, Issue.2
, pp. 163-179
-
-
Sun, N.1
Zhao, H.2
-
104
-
-
10044280457
-
Learning module networks from genome-wide location and expression data
-
Xu X, Wang L, Ding D. Learning module networks from genome-wide location and expression data. FEBS Lett. 578(3), 297-304 (2004
-
(2004)
FEBS Lett
, vol.578
, Issue.3
, pp. 297-304
-
-
Xu, X.1
Wang, L.2
Ding, D.3
-
105
-
-
60149110901
-
Module networks revisited: Computational assessment and prioritization of model predictions
-
Joshi A, De Smet R, Marchal K, Van de Peer Y, Michoel T. Module networks revisited: Computational assessment and prioritization of model predictions. Bioinformatics 25(4), 490-496 (2009
-
(2009)
Bioinformatics
, vol.25
, Issue.4
, pp. 490-496
-
-
Joshi, A.1
De Smet, R.2
Marchal, K.3
Van De Peer, Y.4
Michoel, T.5
-
106
-
-
0037941585
-
Module networks: Identifying regulatory modules and their condition-specific regulators from gene expression data
-
Segal E, Shapira M, Regev A et al. Module networks: Identifying regulatory modules and their condition-specific regulators from gene expression data. Nat. Genet. 34(2), 166-176 (2003
-
(2003)
Nat. Genet.
, vol.34
, Issue.2
, pp. 166-176
-
-
Segal, E.1
Shapira, M.2
Regev, A.3
-
107
-
-
26844520628
-
Profiling of genes expressed in peripheral blood mononuclear cells predicts glucocorticoid sensitivity in asthma patients
-
Hakonarson H, Bjornsdottir US, Halapi E et al. Profiling of genes expressed in peripheral blood mononuclear cells predicts glucocorticoid sensitivity in asthma patients. Proc. Natl Acad. Sci. USA 102(41), 14789-14794 (2005
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, Issue.41
, pp. 14789-14794
-
-
Hakonarson, H.1
Bjornsdottir, U.S.2
Halapi, E.3
-
108
-
-
40649110514
-
A functional and regulatory map of asthma
-
Novershtern N, Itzhaki Z, Manor O, Friedman N, Kaminski N. A functional and regulatory map of asthma. Am. J. Respir. Cell Mol. Biol. 38(3), 324-336 (2008
-
(2008)
Am. J. Respir. Cell Mol. Biol.
, vol.38
, Issue.3
, pp. 324-336
-
-
Novershtern, N.1
Itzhaki, Z.2
Manor, O.3
Friedman, N.4
Kaminski, N.5
-
109
-
-
52049087356
-
Endotyping asthma: Mew insights into key pathogenic mechanisms in a complex, heterogeneous disease
-
Anderson GP. Endotyping asthma: Mew insights into key pathogenic mechanisms in a complex, heterogeneous disease. Lancet 372(9643), 1107-1119 (2008
-
(2008)
Lancet
, vol.372
, Issue.9643
, pp. 1107-1119
-
-
Anderson, G.P.1
-
110
-
-
62449280845
-
-
Respiratory Genetics (Volume 1). Shapiro SJ, Lomas D, Weiss ST, Silverman E (Eds Hodder Education, London, UK
-
Tantisira K, Drazen JM. Pharmacogenetics. In: Respiratory Genetics (Volume 1). Shapiro SJ, Lomas D, Weiss ST, Silverman E (Eds). Hodder Education, London, UK, 191-216 (2005
-
(2005)
Pharmacogenetics
, pp. 191-216
-
-
Tantisira, K.1
Drazen, J.M.2
-
111
-
-
80052668572
-
Genome-wide association studies of asthma
-
Tamari M, Tomita K, Hirota T. Genome-wide association studies of asthma. Allergol. Int. 60(3), 247-252 (2011
-
(2011)
Allergol. Int.
, vol.60
, Issue.3
, pp. 247-252
-
-
Tamari, M.1
Tomita, K.2
Hirota, T.3
-
113
-
-
79959337977
-
A trial of hierarchical cluster analysis of hospitalized wheezy infants and young children based on clinical factors
-
Isozaki A, Shoda T, Mimura S et al. A trial of hierarchical cluster analysis of hospitalized wheezy infants and young children based on clinical factors. Arerugi 60(5), 586-592 (2011
-
(2011)
Arerugi
, vol.60
, Issue.5
, pp. 586-592
-
-
Isozaki, A.1
Shoda, T.2
Mimura, S.3
-
114
-
-
79551500941
-
Heterogeneity of severe asthma in childhood: Confirmation by cluster analysis of children in the national institutes of health/ national heart
-
Lung, and Blood Institute Severe Asthma Research Program 1-13
-
Fitzpatrick AM, Teague WG, Meyers DA et al. Heterogeneity of severe asthma in childhood: Confirmation by cluster analysis of children in the National Institutes of Health/ National Heart, Lung, and Blood Institute Severe Asthma Research Program. J. Allergy Clin. Immunol. 127(2), 382-389.e1-13 (2011
-
(2011)
J. Allergy Clin. Immunol.
, vol.127
, Issue.2
-
-
Fitzpatrick, A.M.1
Teague, W.G.2
Meyers, D.A.3
-
115
-
-
69249098135
-
Distinct clinical phenotypes of airways disease defined by cluster analysis
-
Weatherall M, Travers J, Shirtcliffe PM et al. Distinct clinical phenotypes of airways disease defined by cluster analysis. Eur. Respir. J. 34(4), 812-818 (2009
-
(2009)
Eur. Respir. J.
, vol.34
, Issue.4
, pp. 812-818
-
-
Weatherall, M.1
Travers, J.2
Shirtcliffe, P.M.3
-
116
-
-
78049420683
-
An immune response network associated with blood lipid levels
-
Inouye M, Silander K, Hamalainen E et al. An immune response network associated with blood lipid levels. PLoS Genet. 6(9), e1001113 (2010
-
(2010)
Plos Genet
, vol.6
, Issue.9
-
-
Inouye, M.1
Silander, K.2
Hamalainen, E.3
-
118
-
-
79851479498
-
Global analysis of the impact of environmental perturbation on cis-regulation of gene expression
-
Grundberg E, Adoue V, Kwan T et al. Global analysis of the impact of environmental perturbation on cis-regulation of gene expression. PLoS Genet. 7(1), e1001279 (2011
-
(2011)
Plos Genet
, vol.7
, Issue.1
-
-
Grundberg, E.1
Adoue, V.2
Kwan, T.3
-
119
-
-
0030870119
-
Tenascin is increased in airway basement membrane of asthmatics and decreased by an inhaled steroid
-
Pt 1
-
Laitinen A, Altraja A, Kampe M, Linden M, Virtanen I, Laitinen LA. Tenascin is increased in airway basement membrane of asthmatics and decreased by an inhaled steroid. Am. J. Respir. Crit. Care Med. 156(3 Pt 1), 951-958 (1997
-
(1997)
Am. J. Respir. Crit. Care Med.
, vol.156
, Issue.3
, pp. 951-958
-
-
Laitinen, A.1
Altraja, A.2
Kampe, M.3
Linden, M.4
Virtanen, I.5
Laitinen, L.A.6
-
120
-
-
34548805282
-
A genome-wide association study of global gene expression
-
Dixon AL, Liang L, Moffatt MF et al. A genome-wide association study of global gene expression. Nat. Genet. 39(10), 1202-1207 (2007
-
(2007)
Nat. Genet.
, vol.39
, Issue.10
, pp. 1202-1207
-
-
Dixon, A.L.1
Liang, L.2
Moffatt, M.F.3
-
121
-
-
34548738566
-
Population genomics of human gene expression
-
Stranger BE, Nica AC, Forrest MS et al. Population genomics of human gene expression. Nat. Genet. 39(10), 1217-1224 (2007
-
(2007)
Nat. Genet.
, vol.39
, Issue.10
, pp. 1217-1224
-
-
Stranger, B.E.1
Nica, A.C.2
Forrest, M.S.3
-
122
-
-
0034710924
-
Discovering functional relationships between RNA expression and chemotherapeutic susceptibility using relevance networks
-
Butte AJ, Tamayo P, Slonim D, Golub TR, Kohane IS. Discovering functional relationships between RNA expression and chemotherapeutic susceptibility using relevance networks. Proc. Natl Acad. Sci. USA 97(22), 12182-12186 (2000
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, Issue.22
, pp. 12182-12186
-
-
Butte, A.J.1
Tamayo, P.2
Slonim, D.3
Golub, T.R.4
Kohane, I.S.5
-
123
-
-
33746265419
-
Novel integrative genomics strategies to identify genes for complex traits
-
Schadt EE. Novel integrative genomics strategies to identify genes for complex traits. Anim. Genet. 37(Suppl. 1), 18-23 (2006
-
(2006)
Anim. Genet.
, vol.37
, Issue.SUPPL. 1
, pp. 18-23
-
-
Schadt, E.E.1
-
124
-
-
22844446947
-
An integrative genomics approach to infer causal associations between gene expression and disease
-
Schadt EE, Lamb J, Yang X et al. An integrative genomics approach to infer causal associations between gene expression and disease. Nat. Genet. 37(7), 710-717 (2005
-
(2005)
Nat. Genet.
, vol.37
, Issue.7
, pp. 710-717
-
-
Schadt, E.E.1
Lamb, J.2
Yang, X.3
-
125
-
-
15944364151
-
An empirical Bayes approach to inferring large-scale gene association networks
-
Schafer J, Strimmer K. An empirical Bayes approach to inferring large-scale gene association networks. Bioinformatics 21(6), 754-764 (2005
-
(2005)
Bioinformatics
, vol.21
, Issue.6
, pp. 754-764
-
-
Schafer, J.1
Strimmer, K.2
-
126
-
-
67651015931
-
A graphical model approach for inferring large-scale networks integrating gene expression and genetic polymorphism
-
Chu JH, Weiss ST, Carey VJ, Raby BA. A graphical model approach for inferring large-scale networks integrating gene expression and genetic polymorphism. BMC Syst. Biol. 3, 55 (2009
-
(2009)
BMC Syst. Biol.
, vol.3
, pp. 55
-
-
Chu, J.H.1
Weiss, S.T.2
Carey, V.J.3
Raby, B.A.4
-
127
-
-
0036081355
-
Gene Expression Omnibus: MCBI gene expression and hybridization array data repository
-
Edgar R, Domrachev M, Lash AE. Gene Expression Omnibus: MCBI gene expression and hybridization array data repository. Nucleic Acids Res. 30(1), 207-210 (2002
-
(2002)
Nucleic Acids Res
, vol.30
, Issue.1
, pp. 207-210
-
-
Edgar, R.1
Domrachev, M.2
Lash, A.E.3
|