A screening methodology based on Random Forests to improve the detection of gene-gene interactions

European Journal of Human Genetics

Volumn 18, Issue 10, 2010, Pages 1127-1132

  De Lobel, Lizzy ^a   Geurts, Pierre ^b   Baele, Guy ^a,c   Castro Giner, Francesc ^d,e,f   Kogevinas, Manolis ^d,e,f   Van Steen, Kristel ^b,g  

^a GHENT UNIVERSITY   (Belgium)

^b UNIVERSITY OF LIÈGE   (Belgium)

^c Department of Plant Systems Biology ^*  (Belgium)

^d CENTRE FOR RESEARCH IN ENVIRONMENTAL EPIDEMIOLOGY CREAL   (Spain)

^e HOSPITAL DEL MAR   (Spain)

^f CIBER EPIDEMIOLOGÍA Y SALUD PÚBLICA CIBERESP   (Spain)

^g GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

gene gene interactions; Multifactor Dimensionality Reduction; prescreening; Random Forests

Indexed keywords

ARTICLE; COMPUTER PROGRAM; COMPUTER SIMULATION; GENE INTERACTION; GENE LOCUS; GENETIC SCREENING; GENETIC SUSCEPTIBILITY; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ALGORITHMS; ASTHMA; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; DECISION TREES; EPISTASIS, GENETIC; EUROPE; GENE EXPRESSION; GENETIC ASSOCIATION STUDIES; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; GENETIC TESTING; HUMANS; MODELS, GENETIC; MULTIFACTOR DIMENSIONALITY REDUCTION; POLYMORPHISM, SINGLE NUCLEOTIDE; STATISTICS AS TOPIC;

EID: 77957157531     PISSN: 10184813     EISSN: 14765438     Source Type: Journal    
DOI: 10.1038/ejhg.2010.48     Document Type: Article

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