Leukotriene C4 synthase gene A(-444)C polymorphism and clinical response to a CYS-LT1 antagonist, pranlukast, in Japanese patients with moderate asthma

Pharmacogenetics

Volumn 12, Issue 7, 2002, Pages 565-570

  Asano, Koichiro ^a   Shiomi, Tetsuya ^a   Hasegawa, Naoki ^a   Nakamura, Hidetoshi ^a   Kudo, Hiroyasu ^a   Matsuzaki, Tatsu ^a   Hakuno, Haruhiko ^a   Fukunaga, Kouichi ^a   Suzuki, Yusuke ^a   Kanazawa, Minoru ^a   Yamaguchi, Kazuhiro ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Asthma; CysLT1 antagonist; Leukotriene C4 synthase

Indexed keywords

BECLOMETASONE; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CORTICOSTEROID; FLUTICASONE; LEUKOTRIENE C4 SYNTHASE; LEUKOTRIENE E4; PRANLUKAST; SALBUTAMOL; ANDROSTANE DERIVATIVE; ANTIASTHMATIC AGENT; CHROMONE DERIVATIVE; GLUTATHIONE TRANSFERASE; LEUKOTRIENE RECEPTOR BLOCKING AGENT; LEUKOTRIENE-C4 SYNTHASE;

ADULT; AGE; AGED; AIRWAY RESISTANCE; ALLELE; ARTICLE; ASTHMA; ATOPY; BRONCHODILATING ACTIVITY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; DNA SEQUENCE; DOSE RESPONSE; DRUG EFFICACY; FEMALE; FORCED EXPIRATORY VOLUME; GENE FREQUENCY; GENETIC POLYMORPHISM; GENOTYPE; HEADACHE; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MALE; PHARMACOGENETICS; PRIORITY JOURNAL; RASH; RISK FACTOR; SEX DIFFERENCE; TREATMENT OUTCOME; TREATMENT PLANNING; URINARY EXCRETION; ANALYSIS OF VARIANCE; ASIAN; COMPARATIVE STUDY; ENZYMOLOGY; GENETICS; HETEROZYGOTE DETECTION; INHALATIONAL DRUG ADMINISTRATION; JAPAN; MIDDLE AGED; PATHOPHYSIOLOGY; PROMOTER REGION; SINGLE NUCLEOTIDE POLYMORPHISM;

ADMINISTRATION, INHALATION; ADULT; ALBUTEROL; ANALYSIS OF VARIANCE; ANDROSTADIENES; ANTI-ASTHMATIC AGENTS; ASIAN CONTINENTAL ANCESTRY GROUP; ASTHMA; BECLOMETHASONE; CHROMONES; FEMALE; FORCED EXPIRATORY VOLUME; GLUTATHIONE TRANSFERASE; HETEROZYGOTE DETECTION; HUMANS; JAPAN; LEUKOTRIENE ANTAGONISTS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS (GENETICS);

EID: 18644372214     PISSN: 0960314X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008571-200210000-00009     Document Type: Article

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