TBX21: A functional variant predicts improvement in asthma with the use of inhaled corticosteroids

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 52, 2004, Pages 18099-18104

  Tantisira, Kelan G ^a,d   Hwang, Eun Sook ^b   Raby, Benjamin A ^a   Silverman, Eric S ^a,b   Lake, Stephen L ^a   Richter, Brent G ^a   Peng, Stanford L ^c   Drazen, Jeffrey M ^a,b   Glimcher, Laurie H ^b   Weiss, Scott T ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d CHANNING LABORATORY   (United States)

Author keywords

Interaction; PC20; Pharmacogenetics; T bet

Indexed keywords

BUDESONIDE; CORTICOSTEROID; DEXAMETHASONE; METHACHOLINE; PLACEBO; T BOX TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR T BET; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; ASTHMA; BRONCHUS HYPERREACTIVITY; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOUBLE BLIND PROCEDURE; FEMALE; FOLLOW UP; FORCED EXPIRATORY VOLUME; GENE; GENETIC VARIABILITY; HUMAN; KNOCKOUT MOUSE; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NUCLEOTIDE SEQUENCE; PHARMACOGENETICS; PRIORITY JOURNAL; PROVOCATION TEST; RANDOMIZED CONTROLLED TRIAL; TBX21 GENE; TH1 CELL; TH2 CELL; WILD TYPE;

ADMINISTRATION, INHALATION; ADRENAL CORTEX HORMONES; ALLELES; ASTHMA; CHILD; CHILD, PRESCHOOL; CLINICAL TRIALS; CYTOKINES; DEXAMETHASONE; DNA, COMPLEMENTARY; FEMALE; GENOTYPE; GLUTAMINE; HISTIDINE; HUMANS; MALE; MUTAGENESIS, SITE-DIRECTED; PHENOTYPE; T-BOX DOMAIN PROTEINS; TH1 CELLS; TH2 CELLS; TIME FACTORS; VARIATION (GENETICS);

BRONCHUS;

EID: 19944427616     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0408532102     Document Type: Article

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