-
1
-
-
31444456593
-
Decreases in Hispanic and non-Hispanic asthma mortality
-
Sly RM. Decreases in Hispanic and non-Hispanic asthma mortality. Ann Allergy Asthma Immunol 2006; 96: 76-9
-
(2006)
Ann Allergy Asthma Immunol
, vol.96
, pp. 76-79
-
-
Sly, R.M.1
-
2
-
-
16344377335
-
-
American Lung Association, online, Available from URL:, Accessed Mar 2
-
American Lung Association. Trends in asthma morbidity and mortality [online]. Available from URL: http://www.lungusa.org/atf/cf/%7B7A8D42C2-FC-CA- 4604-8ADE-7F5D5E762256%7D/ASTHMA1.PDF [Accessed 2007 Mar 2]
-
(2007)
Trends in asthma morbidity and mortality
-
-
-
3
-
-
0033059209
-
Pharmacogenetic association between ALOX5 promoter genotype and the response to anti-asthma treatment
-
Drazen JM, Yandava CN, Dube L, et al. Pharmacogenetic association between ALOX5 promoter genotype and the response to anti-asthma treatment. Nat Genet 1999; 22: 168-70
-
(1999)
Nat Genet
, vol.22
, pp. 168-170
-
-
Drazen, J.M.1
Yandava, C.N.2
Dube, L.3
-
4
-
-
1342332173
-
The common variants/multiple disease hypothesis of common complex genetic disorders
-
Becker KG. The common variants/multiple disease hypothesis of common complex genetic disorders. Med Hypotheses 2004; 62: 309-17
-
(2004)
Med Hypotheses
, vol.62
, pp. 309-317
-
-
Becker, K.G.1
-
5
-
-
85039177338
-
-
Lima JJ, Wang J. Respiratory diseases. In: American College of Clinical Pharmacy, editor. Pharmacogenomics: applications to patient care. Kansas City (MO): ACCP, 2004: 571-611
-
Lima JJ, Wang J. Respiratory diseases. In: American College of Clinical Pharmacy, editor. Pharmacogenomics: applications to patient care. Kansas City (MO): ACCP, 2004: 571-611
-
-
-
-
7
-
-
0842307212
-
Trends in pharmacogenomics of drugs used in the treatment of asthma
-
Pignatti PF. Trends in pharmacogenomics of drugs used in the treatment of asthma. Pharmacol Res 2004; 49: 343-9
-
(2004)
Pharmacol Res
, vol.49
, pp. 343-349
-
-
Pignatti, P.F.1
-
8
-
-
14744293163
-
Pharmacogenetic approaches in the treatment of asthma
-
Sayers I, Hall IP. Pharmacogenetic approaches in the treatment of asthma. Curr Allergy Asthma Rep 2005; 5: 101-8
-
(2005)
Curr Allergy Asthma Rep
, vol.5
, pp. 101-108
-
-
Sayers, I.1
Hall, I.P.2
-
9
-
-
33746842930
-
Overview of the pharmacogenetics of asthma treatment
-
Weiss ST, Litonjua AA, Lange C, et al. Overview of the pharmacogenetics of asthma treatment. Pharmacogenomics 2006; 6: 311-26
-
(2006)
Pharmacogenomics
, vol.6
, pp. 311-326
-
-
Weiss, S.T.1
Litonjua, A.A.2
Lange, C.3
-
10
-
-
33747805014
-
Pharmacological management of mild or moderate persistent asthma
-
O'Byrne PM, Parameswaran K. Pharmacological management of mild or moderate persistent asthma. Lancet 2006; 368: 794-803
-
(2006)
Lancet
, vol.368
, pp. 794-803
-
-
O'Byrne, P.M.1
Parameswaran, K.2
-
12
-
-
33646245920
-
The role of leukotrienes in the pathophysiology of inflammatory disorders: Is there a case for revisiting leukotrienes as therapeutic targets?
-
Sharma JN, Mohammed LA. The role of leukotrienes in the pathophysiology of inflammatory disorders: is there a case for revisiting leukotrienes as therapeutic targets? Inflammopharmacology 2006; 14: 10-6
-
(2006)
Inflammopharmacology
, vol.14
, pp. 10-16
-
-
Sharma, J.N.1
Mohammed, L.A.2
-
14
-
-
5144232253
-
Novel inhibitory effect on 5-lipoxygenase activity by the anti-asthma drug montelukast
-
Ramires R, Caiaffa MF, Tursi A, et al. Novel inhibitory effect on 5-lipoxygenase activity by the anti-asthma drug montelukast. Biochem Biophys Res Commun 2004; 324: 815-21
-
(2004)
Biochem Biophys Res Commun
, vol.324
, pp. 815-821
-
-
Ramires, R.1
Caiaffa, M.F.2
Tursi, A.3
-
15
-
-
0036855114
-
National Heart, Lung, and Blood Institute. National Asthma Education and Prevention Program. Expert panel report: Guidelines for the diagnosis and management of asthma update on selected topics 2002: NAEPP2002
-
National Institutes of Health
-
National Institutes of Health: National Heart, Lung, and Blood Institute. National Asthma Education and Prevention Program. Expert panel report: guidelines for the diagnosis and management of asthma update on selected topics 2002: NAEPP2002. J Allergy Clin Immunol 2002; 110: S142-219
-
(2002)
J Allergy Clin Immunol
, vol.110
-
-
-
17
-
-
0028103864
-
Effects of 6 weeks of therapy with oral doses of ICI 204,219, a leukotriene D4 receptor antagonist, in subjects with bronchial asthma. ACCOLATE Asthma Trialists Group
-
Spector SL, Smith LJ, Glass M. Effects of 6 weeks of therapy with oral doses of ICI 204,219, a leukotriene D4 receptor antagonist, in subjects with bronchial asthma. ACCOLATE Asthma Trialists Group. Am J Respir Crit Care Med 1994; 150: 618-23
-
(1994)
Am J Respir Crit Care Med
, vol.150
, pp. 618-623
-
-
Spector, S.L.1
Smith, L.J.2
Glass, M.3
-
18
-
-
0029853741
-
Acute and chronic effects of a 5-lipoxygenase inhibitor in asthma: A 6-month randomized multicenter trial. Zileuton Study Group
-
Liu MC, Dube LM, Lancaster J. Acute and chronic effects of a 5-lipoxygenase inhibitor in asthma: a 6-month randomized multicenter trial. Zileuton Study Group. J Allergy Clin Immunol 1996; 98: 859-71
-
(1996)
J Allergy Clin Immunol
, vol.98
, pp. 859-871
-
-
Liu, M.C.1
Dube, L.M.2
Lancaster, J.3
-
19
-
-
0031057451
-
Effectiveness of the leukotriene receptor antagonist zafirlukast for mild-to-moderate asthma: A randomized, doubleblind, placebo-controlled trial
-
Suissa S, Dennis R, Ernst P, et al. Effectiveness of the leukotriene receptor antagonist zafirlukast for mild-to-moderate asthma: a randomized, doubleblind, placebo-controlled trial. Ann Intern Med 1997; 126: 177-83
-
(1997)
Ann Intern Med
, vol.126
, pp. 177-183
-
-
Suissa, S.1
Dennis, R.2
Ernst, P.3
-
20
-
-
0032496618
-
Montelukast, a once-daily leukotriene receptor antagonist, in the treatment of chronic asthma: A multicenter, randomized, double-blind trial. Montelukast Clinical Research Study Group
-
Reiss TF, Chervinsky P, Dockhorn RJ, et al. Montelukast, a once-daily leukotriene receptor antagonist, in the treatment of chronic asthma: a multicenter, randomized, double-blind trial. Montelukast Clinical Research Study Group. Arch Intern Med 1998; 158: 1213-20
-
(1998)
Arch Intern Med
, vol.158
, pp. 1213-1220
-
-
Reiss, T.F.1
Chervinsky, P.2
Dockhorn, R.J.3
-
21
-
-
0031110457
-
Randomized trial of zileuton in patients with moderate asthma: Effect of reduced dosing frequency and amounts on pulmonary function and asthma symptoms. Zileuton Study Group
-
DuBuske LM, Grossman J, Dube LM, et al. Randomized trial of zileuton in patients with moderate asthma: effect of reduced dosing frequency and amounts on pulmonary function and asthma symptoms. Zileuton Study Group. Am J Manag Care 1997; 3: 633-40
-
(1997)
Am J Manag Care
, vol.3
, pp. 633-640
-
-
DuBuske, L.M.1
Grossman, J.2
Dube, L.M.3
-
22
-
-
0033574195
-
Oral montelukast, inhaled beclomethasone, and placebo for chronic asthma: A randomized, controlled trial. Montelukast/Beclomethasone Study Group
-
Malmstrom K, Rodriguez-Gomez G, Guerra J, et al. Oral montelukast, inhaled beclomethasone, and placebo for chronic asthma: a randomized, controlled trial. Montelukast/Beclomethasone Study Group. Ann Intern Med 1999; 130: 487-95
-
(1999)
Ann Intern Med
, vol.130
, pp. 487-495
-
-
Malmstrom, K.1
Rodriguez-Gomez, G.2
Guerra, J.3
-
23
-
-
0036907604
-
Effects of montelukast and beclomethasone on airway function and asthma control
-
Israel E, Chervinsky PS, Friedman B, et al. Effects of montelukast and beclomethasone on airway function and asthma control. J Allergy Clin Immunol 2002; 110: 847-54
-
(2002)
J Allergy Clin Immunol
, vol.110
, pp. 847-854
-
-
Israel, E.1
Chervinsky, P.S.2
Friedman, B.3
-
24
-
-
13444254245
-
Characterization of within-subject responses to fluticasone and montelukast in childhood asthma
-
Szefler SJ, Phillips BR, Martinez FD, et al. Characterization of within-subject responses to fluticasone and montelukast in childhood asthma. J Allergy Clin Immunol 2005; 115: 233-42
-
(2005)
J Allergy Clin Immunol
, vol.115
, pp. 233-242
-
-
Szefler, S.J.1
Phillips, B.R.2
Martinez, F.D.3
-
25
-
-
0027762572
-
The pivotal role of 5-lipoxygenase products in the reaction of aspirin-sensitive asthmatics to aspirin
-
Israel E, Fischer AR, Rosenberg MA, et al. The pivotal role of 5-lipoxygenase products in the reaction of aspirin-sensitive asthmatics to aspirin. Am Rev Respir Dis 1993; 148: 1447-51
-
(1993)
Am Rev Respir Dis
, vol.148
, pp. 1447-1451
-
-
Israel, E.1
Fischer, A.R.2
Rosenberg, M.A.3
-
26
-
-
19244370387
-
Benefits from adding the 5-lipoxygenase inhibitor zileuton to conventional therapy in aspirin-intolerant asthmatics
-
Dahlen B, Nizankowska E, Szczeklik A, et al. Benefits from adding the 5-lipoxygenase inhibitor zileuton to conventional therapy in aspirin-intolerant asthmatics. Am J Respir Crit Care Med 1998; 157: 1187-94
-
(1998)
Am J Respir Crit Care Med
, vol.157
, pp. 1187-1194
-
-
Dahlen, B.1
Nizankowska, E.2
Szczeklik, A.3
-
27
-
-
0025951165
-
The potent and selective sulfidopeptide leukotriene antagonist, SK&F 104353, inhibits aspirin-induced asthma
-
Christie PE, Smith CM, Lee TH. The potent and selective sulfidopeptide leukotriene antagonist, SK&F 104353, inhibits aspirin-induced asthma. Am Rev Respir Dis 1991; 144: 957-8
-
(1991)
Am Rev Respir Dis
, vol.144
, pp. 957-958
-
-
Christie, P.E.1
Smith, C.M.2
Lee, T.H.3
-
28
-
-
0037193820
-
Anti-leukotrienes as add-on therapy to inhaled glucocorticoids in patients with asthma: Systematic review of current evidence
-
Ducharme FM. Anti-leukotrienes as add-on therapy to inhaled glucocorticoids in patients with asthma: systematic review of current evidence. BMJ 2002; 324: 1545-8
-
(2002)
BMJ
, vol.324
, pp. 1545-1548
-
-
Ducharme, F.M.1
-
29
-
-
34147176795
-
Long-acting beta2-agonists versus antileukotrienes as add-on therapy to inhaled corticosteroids for chronic asthma
-
CD003137
-
Ducharme FM, Lasserson TJ, Cates CJ. Long-acting beta2-agonists versus antileukotrienes as add-on therapy to inhaled corticosteroids for chronic asthma. Cochrane Database Syst Rev 2006; (4): CD003137
-
(2006)
Cochrane Database Syst Rev
, Issue.4
-
-
Ducharme, F.M.1
Lasserson, T.J.2
Cates, C.J.3
-
30
-
-
33846829665
-
Clinical trial of low-dose theophylline and montelukast in patients with poorly controlled asthma
-
American Lung Association Asthma Clinical Research Centers
-
American Lung Association Asthma Clinical Research Centers. Clinical trial of low-dose theophylline and montelukast in patients with poorly controlled asthma. Am J Respir Crit Care Med 2007; 175: 235-42
-
(2007)
Am J Respir Crit Care Med
, vol.175
, pp. 235-242
-
-
-
31
-
-
32444440309
-
Influence of leukotriene pathway polymorphisms on response to montelukast in asthma
-
Lima JJ, Zhang S, Grant A, et al. Influence of leukotriene pathway polymorphisms on response to montelukast in asthma. Am J Respir Crit Care Med 2006; 173: 379-85
-
(2006)
Am J Respir Crit Care Med
, vol.173
, pp. 379-385
-
-
Lima, J.J.1
Zhang, S.2
Grant, A.3
-
32
-
-
0037421590
-
Pharmacogenomics: Drug disposition, drug targets, and side effects
-
Evans WE, McLeod HL. Pharmacogenomics: drug disposition, drug targets, and side effects. N Engl J Med 2003; 348: 538-49
-
(2003)
N Engl J Med
, vol.348
, pp. 538-549
-
-
Evans, W.E.1
McLeod, H.L.2
-
33
-
-
0031003816
-
Naturally occurring mutations in the human 5-lipoxygenase gene promoter that modify transcription factor binding and reporter gene transcription
-
In KH, Asano K, Beier D, et al. Naturally occurring mutations in the human 5-lipoxygenase gene promoter that modify transcription factor binding and reporter gene transcription. J Clin Invest 1997; 99: 1130-7
-
(1997)
J Clin Invest
, vol.99
, pp. 1130-1137
-
-
In, K.H.1
Asano, K.2
Beier, D.3
-
34
-
-
0033803781
-
Variant LTC(4) synthase allele modifies cysteinyl leukotriene synthesis in eosinophils and predicts clinical response to zafirlukast
-
Sampson AP, Siddiqui S, Buchanan D, et al. Variant LTC(4) synthase allele modifies cysteinyl leukotriene synthesis in eosinophils and predicts clinical response to zafirlukast. Thorax 2000; 55 Suppl. 2: S28-31
-
(2000)
Thorax
, vol.55
, Issue.SUPPL. 2
-
-
Sampson, A.P.1
Siddiqui, S.2
Buchanan, D.3
-
35
-
-
18644372214
-
Leukotriene C4 synthase gene A(-444)C polymorphism and clinical response to a CYS-LT(1) antagonist, pranlukast, in Japanese patients with moderate asthma
-
Asano K, Shiomi T, Hasegawa N, et al. Leukotriene C4 synthase gene A(-444)C polymorphism and clinical response to a CYS-LT(1) antagonist, pranlukast, in Japanese patients with moderate asthma. Pharmacogenetics 2002; 12: 565-70
-
(2002)
Pharmacogenetics
, vol.12
, pp. 565-570
-
-
Asano, K.1
Shiomi, T.2
Hasegawa, N.3
-
36
-
-
0142031051
-
Effect of montelukast on time-course of exhaled nitric oxide in asthma: Influence of LTC4 synthase A(-444)C polymorphism
-
Whelan GJ, Blake K, Kissoon N, et al. Effect of montelukast on time-course of exhaled nitric oxide in asthma: influence of LTC4 synthase A(-444)C polymorphism. Pediatr Pulmonol 2003; 36: 413-20
-
(2003)
Pediatr Pulmonol
, vol.36
, pp. 413-420
-
-
Whelan, G.J.1
Blake, K.2
Kissoon, N.3
-
37
-
-
0141505006
-
Leukotriene C4 synthase polymorphisms and responsiveness to leukotriene antagonists in asthma
-
Currie GP, Lima JJ, Sylvester JE, et al. Leukotriene C4 synthase polymorphisms and responsiveness to leukotriene antagonists in asthma. Br J Clin Pharmacol 2003; 56: 422-6
-
(2003)
Br J Clin Pharmacol
, vol.56
, pp. 422-426
-
-
Currie, G.P.1
Lima, J.J.2
Sylvester, J.E.3
-
38
-
-
11344267023
-
Uncertain biological relevance of polymorphisms of leukotriene C4 synthase in asthma [letter]
-
Currie GP, Lee DK. Uncertain biological relevance of polymorphisms of leukotriene C4 synthase in asthma [letter]. J Allergy Clin Immunol 2005; 115: 205
-
(2005)
J Allergy Clin Immunol
, vol.115
, pp. 205
-
-
Currie, G.P.1
Lee, D.K.2
-
39
-
-
29444444748
-
A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarction
-
Helgadottir A, Manolescu A, Helgason A, et al. A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarction. Nat Genet 2006; 38: 68-74
-
(2006)
Nat Genet
, vol.38
, pp. 68-74
-
-
Helgadottir, A.1
Manolescu, A.2
Helgason, A.3
-
40
-
-
0028805995
-
The pharmacokinetics of single oral doses of zileuton 200 to 800mg, its enantiomers, and its metabolites, in normal healthy volunteers
-
Wong SL, Awni WN, Cavanaugh JH, et al. The pharmacokinetics of single oral doses of zileuton 200 to 800mg, its enantiomers, and its metabolites, in normal healthy volunteers. Clin Pharmacokinet 1995; 29 Suppl. 2: 9-21
-
(1995)
Clin Pharmacokinet
, vol.29
, Issue.SUPPL. 2
, pp. 9-21
-
-
Wong, S.L.1
Awni, W.N.2
Cavanaugh, J.H.3
-
41
-
-
0142243111
-
Mechanism-based inhibition of human liver microsomal cytochrome P450 1A2 by zileuton, a 5-lipoxygenase inhibitor
-
Lu P, Schrag ML, Slaughter DE, et al. Mechanism-based inhibition of human liver microsomal cytochrome P450 1A2 by zileuton, a 5-lipoxygenase inhibitor. Drug Metab Dispos 2003; 31: 1352-60
-
(2003)
Drug Metab Dispos
, vol.31
, pp. 1352-1360
-
-
Lu, P.1
Schrag, M.L.2
Slaughter, D.E.3
-
42
-
-
0028791821
-
In vitro plasma protein binding of zileuton and its N-dehydroxylated metabolite
-
Machinist JM, Kukulka MJ, Bopp BA. In vitro plasma protein binding of zileuton and its N-dehydroxylated metabolite. Clin Pharmacokinet 1995; 29 Suppl. 2: 34-41
-
(1995)
Clin Pharmacokinet
, vol.29
, Issue.SUPPL. 2
, pp. 34-41
-
-
Machinist, J.M.1
Kukulka, M.J.2
Bopp, B.A.3
-
43
-
-
0030995469
-
Pharmacokinetics of zileuton and its metabolites in patients with renal impairment
-
Awni WM, Wong S, Chu SY, et al. Pharmacokinetics of zileuton and its metabolites in patients with renal impairment. J Clin Pharmacol 1997; 37: 395-404
-
(1997)
J Clin Pharmacol
, vol.37
, pp. 395-404
-
-
Awni, W.M.1
Wong, S.2
Chu, S.Y.3
-
44
-
-
34147147252
-
Pharmacogenetics of oxidative drug metabolism and its clinical applications
-
Thomas SJ, editor, Kansas City MO, American College of Clinical Pharmacy
-
Frye R. Pharmacogenetics of oxidative drug metabolism and its clinical applications. In: Thomas SJ, editor. Pharmacogenomics. Kansas City (MO): American College of Clinical Pharmacy, 2004: 273-307
-
(2004)
Pharmacogenomics
, pp. 273-307
-
-
Frye, R.1
-
45
-
-
0031776628
-
Chemistry and structure: Activity relationships of leukotriene receptor antagonists
-
Bernstein PR. Chemistry and structure: activity relationships of leukotriene receptor antagonists. Am J Respir Crit Care Med 1998; 157: S220-5
-
(1998)
Am J Respir Crit Care Med
, vol.157
-
-
Bernstein, P.R.1
-
46
-
-
0034010246
-
Montelukast: A review of its therapeutic potential in persistent asthma
-
Jarvis B, Markham A. Montelukast: a review of its therapeutic potential in persistent asthma. Drugs 2000; 59: 891-928
-
(2000)
Drugs
, vol.59
, pp. 891-928
-
-
Jarvis, B.1
Markham, A.2
-
47
-
-
0035105775
-
Zafirlukast: An update of its pharmacology and therapeutic efficacy in asthma
-
Dunn CJ, Goa KL. Zafirlukast: an update of its pharmacology and therapeutic efficacy in asthma. Drugs 2001; 61: 285-315
-
(2001)
Drugs
, vol.61
, pp. 285-315
-
-
Dunn, C.J.1
Goa, K.L.2
-
49
-
-
0038367655
-
Pranlukast: A review of its use in the management of asthma
-
Keam SJ, Lyseng-Williamson KA, Goa KL. Pranlukast: a review of its use in the management of asthma. Drugs 2003; 63: 991-1019
-
(2003)
Drugs
, vol.63
, pp. 991-1019
-
-
Keam, S.J.1
Lyseng-Williamson, K.A.2
Goa, K.L.3
-
50
-
-
0035289779
-
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
-
Lipinski CA, Lombardo F, Dominy BW, et al. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv Drug Deliv Rev 2000; 46: 3-26
-
(2000)
Adv Drug Deliv Rev
, vol.46
, pp. 3-26
-
-
Lipinski, C.A.1
Lombardo, F.2
Dominy, B.W.3
-
51
-
-
33644684769
-
Transporters and drug discovery: Why, when, and how
-
Kim RB. Transporters and drug discovery: why, when, and how. Mol Pharm 2006; 3: 26-32
-
(2006)
Mol Pharm
, vol.3
, pp. 26-32
-
-
Kim, R.B.1
-
52
-
-
21444450864
-
Biochemical and molecular pharmacological aspects of transporters as determinants of drug disposition
-
Sai Y. Biochemical and molecular pharmacological aspects of transporters as determinants of drug disposition. Drug Metab Pharmacokinet 2005; 20: 91-9
-
(2005)
Drug Metab Pharmacokinet
, vol.20
, pp. 91-99
-
-
Sai, Y.1
-
53
-
-
34147138038
-
Drug transporter pharmacogentics
-
Thomas J, editor, Kansas City MO, American College of Clinical Pharmacy
-
Kroetz D, Nyguyen T. Drug transporter pharmacogentics. In: Thomas J, editor. Pharmacogenomics. Kansas City (MO): American College of Clinical Pharmacy, 2004: 309-36
-
(2004)
Pharmacogenomics
, pp. 309-336
-
-
Kroetz, D.1
Nyguyen, T.2
-
54
-
-
0031800792
-
Role of organic cation transporters in drug absorption and elimination
-
Zhang L, Brett CM, Giacomini KM. Role of organic cation transporters in drug absorption and elimination. Annu Rev Pharmacol Toxicol 1998; 38: 431-60
-
(1998)
Annu Rev Pharmacol Toxicol
, vol.38
, pp. 431-460
-
-
Zhang, L.1
Brett, C.M.2
Giacomini, K.M.3
-
55
-
-
33745831231
-
Structure, function, expression, genomic organization, and single nucleotide polymorphisms of human ABCB1 (MDR1), ABCC (MRP), and ABCG2 (BCRP) efflux transporters
-
Choudhuri S, Klaassen CD. Structure, function, expression, genomic organization, and single nucleotide polymorphisms of human ABCB1 (MDR1), ABCC (MRP), and ABCG2 (BCRP) efflux transporters. Int J Toxicol 2006; 25: 231-59
-
(2006)
Int J Toxicol
, vol.25
, pp. 231-259
-
-
Choudhuri, S.1
Klaassen, C.D.2
-
56
-
-
0034821939
-
Role of transport proteins in drug absorption, distribution and excretion
-
Ayrton A, Morgan P. Role of transport proteins in drug absorption, distribution and excretion. Xenobiotica 2001; 31: 469-97
-
(2001)
Xenobiotica
, vol.31
, pp. 469-497
-
-
Ayrton, A.1
Morgan, P.2
-
58
-
-
1242272736
-
Organic anion transporting polypeptides of the OATP/SLC21 family: Phylogenetic classification as OATP/ SLCO superfamily, new nomenclature and molecular/functional properties
-
Hagenbuch B, Meier PJ. Organic anion transporting polypeptides of the OATP/SLC21 family: phylogenetic classification as OATP/ SLCO superfamily, new nomenclature and molecular/functional properties. Pflugers Arch 2004; 447: 653-65
-
(2004)
Pflugers Arch
, vol.447
, pp. 653-665
-
-
Hagenbuch, B.1
Meier, P.J.2
-
59
-
-
33644781452
-
Implications of genetic polymorphisms in drug transporters for pharmacotherapy
-
Kerb R. Implications of genetic polymorphisms in drug transporters for pharmacotherapy. Cancer Lett 2006; 234: 4-33
-
(2006)
Cancer Lett
, vol.234
, pp. 4-33
-
-
Kerb, R.1
-
60
-
-
0030783057
-
Hepatic microsomal metabolism of montelukast, a potent leukotriene D4 receptor antagonist, in humans
-
Chiba M, Xu X, Nishime JA, et al. Hepatic microsomal metabolism of montelukast, a potent leukotriene D4 receptor antagonist, in humans. Drug Metab Dispos 1997; 25: 1022-31
-
(1997)
Drug Metab Dispos
, vol.25
, pp. 1022-1031
-
-
Chiba, M.1
Xu, X.2
Nishime, J.A.3
-
61
-
-
9244265470
-
Pharmacokinetics, bioavailability, and safety of montelukast sodium (MK-0476) in healthy males and females
-
Cheng H, Leff JA, Amin R, et al. Pharmacokinetics, bioavailability, and safety of montelukast sodium (MK-0476) in healthy males and females. Pharm Res 1996; 13: 445-8
-
(1996)
Pharm Res
, vol.13
, pp. 445-448
-
-
Cheng, H.1
Leff, J.A.2
Amin, R.3
-
62
-
-
0030707608
-
Pharmacokinetics and bioavailability of montelukast sodium (MK-0476) in healthy young and elderly volunteers
-
Zhao JJ, Rogers JD, Holland SD, et al. Pharmacokinetics and bioavailability of montelukast sodium (MK-0476) in healthy young and elderly volunteers. Biopharm Drug Dispos 1997; 18: 769-77
-
(1997)
Biopharm Drug Dispos
, vol.18
, pp. 769-777
-
-
Zhao, J.J.1
Rogers, J.D.2
Holland, S.D.3
-
63
-
-
18044374457
-
A population pharmacokinetic model for montelukast disposition in adults and children
-
Ramakrishnan R, Migoya E, Knorr B. A population pharmacokinetic model for montelukast disposition in adults and children. Pharm Res 2005; 22: 532-40
-
(2005)
Pharm Res
, vol.22
, pp. 532-540
-
-
Ramakrishnan, R.1
Migoya, E.2
Knorr, B.3
-
64
-
-
0030696488
-
Metabolic profiles of montelukast sodium (Singulair), a potent cysteinyl leukotriene1 receptor antagonist, in human plasma and bile
-
Balani SK, Xu X, Pratha V, et al. Metabolic profiles of montelukast sodium (Singulair), a potent cysteinyl leukotriene1 receptor antagonist, in human plasma and bile. Drug Metab Dispos 1997; 25: 1282-7
-
(1997)
Drug Metab Dispos
, vol.25
, pp. 1282-1287
-
-
Balani, S.K.1
Xu, X.2
Pratha, V.3
-
66
-
-
33645806523
-
Molecular characterization and inhibition of amanitin uptake into human hepatocytes
-
Letschert K, Faulstich H, Keller D, et al. Molecular characterization and inhibition of amanitin uptake into human hepatocytes. Toxicol Sci 2006; 91: 140-9
-
(2006)
Toxicol Sci
, vol.91
, pp. 140-149
-
-
Letschert, K.1
Faulstich, H.2
Keller, D.3
-
67
-
-
0038637144
-
Involvement of human organic anion transporting polypeptide OATP-B (SLC21A9) in pH-dependent transport across intestinal apical membrane
-
Kobayashi D, Nozawa T, Imai K, et al. Involvement of human organic anion transporting polypeptide OATP-B (SLC21A9) in pH-dependent transport across intestinal apical membrane. J Pharmacol Exp Ther 2003; 306: 703-8
-
(2003)
J Pharmacol Exp Ther
, vol.306
, pp. 703-708
-
-
Kobayashi, D.1
Nozawa, T.2
Imai, K.3
-
68
-
-
0027984511
-
The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates
-
Leier I, Jedlitschky G, Buchholz U, et al. The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates. J Biol Chem 1994; 269: 27807-10
-
(1994)
J Biol Chem
, vol.269
, pp. 27807-27810
-
-
Leier, I.1
Jedlitschky, G.2
Buchholz, U.3
-
69
-
-
0028347079
-
Characterization of the ATP-dependent leukotriene C4 export carrier in mastocytoma cells
-
Leier I, Jedlitschky G, Buchholz U, et al. Characterization of the ATP-dependent leukotriene C4 export carrier in mastocytoma cells. Eur J Biochem 1994; 220: 599-606
-
(1994)
Eur J Biochem
, vol.220
, pp. 599-606
-
-
Leier, I.1
Jedlitschky, G.2
Buchholz, U.3
-
70
-
-
23844530173
-
Leukotriene modifiers as potential therapeutics for cardiovascular disease
-
Funk CD. Leukotriene modifiers as potential therapeutics for cardiovascular disease. Nat Rev Drug Discov 2005; 4: 664-72
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 664-672
-
-
Funk, C.D.1
|