A polymorphism in the thyroid hormone receptor gene is associated with bronchodilator response in asthmatics

Pharmacogenomics Journal

Volumn 13, Issue 2, 2013, Pages 130-136

  Duan, Q L ^a   Du, R ^a   Lasky Su, J ^a   Klanderman, B J ^a   Partch, A B ^a   Peters, S P ^b   Irvin, C G ^c   Hanrahan, J P ^d   Lima, J J ^e   Blake, K V ^e   Liggett, S B ^f   Litonjua, A A ^a   Tantisira, K G ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b WAKE FOREST UNIVERSITY HEALTH SCIENCES   (United States)

^c UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^d CareFusion   (United States)

^e NEMOURS CHILDREN S CLINIC   (United States)

^f UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

association; asthma; bronchodilator response; pharmacogenetics; thyroid hormone receptor ; transcription factor

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BRONCHODILATING AGENT; CORTICOSTEROID; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PARATHYROID HORMONE RECEPTOR; SALBUTAMOL; SHORT ACTING DRUG; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR 12; TRANSCRIPTION FACTOR RUNX1; UNCLASSIFIED DRUG; VITAMIN D RECEPTOR;

ADOLESCENT; ARTICLE; ASTHMA; CHILD; CONTROLLED STUDY; DOWN REGULATION; FEMALE; FORCED EXPIRATORY VOLUME; GENE; GENE FREQUENCY; GENE LOCUS; GENE REPLICATION; GENETIC ASSOCIATION; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; SINGLE NUCLEOTIDE POLYMORPHISM; THRB GENE;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ASTHMA; BIOMARKERS, PHARMACOLOGICAL; BRONCHODILATOR AGENTS; CHILD; CHILD, PRESCHOOL; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION REGULATION; GENETIC ASSOCIATION STUDIES; HAPLOTYPES; HUMANS; MALE; MIDDLE AGED; MYOCYTES, SMOOTH MUSCLE; POLYMORPHISM, SINGLE NUCLEOTIDE; THYROID HORMONE RECEPTORS BETA; TRANSCRIPTION FACTORS;

EID: 84884211479     PISSN: 1470269X     EISSN: 14731150     Source Type: Journal    
DOI: 10.1038/tpj.2011.56     Document Type: Article

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