메뉴 건너뛰기




Volumn 173, Issue 4, 2006, Pages 379-385

Influence of leukotriene pathway polymorphisms on response to montelukast in asthma

Author keywords

Antiinflammatory; Montelukast; Pharmacodynamic; Pharmacogenetic

Indexed keywords

ARACHIDONATE 5 LIPOXYGENASE; ARACHIDONATE 5 LIPOXYGENASE ACTIVATING PROTEIN; CORTICOSTEROID; LEUKOTRIENE; LEUKOTRIENE C4 SYNTHASE; LEUKOTRIENE RECEPTOR; MONTELUKAST; MULTIDRUG RESISTANCE PROTEIN 1; THEOPHYLLINE;

EID: 32444440309     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/rccm.200509-1412OC     Document Type: Article
Times cited : (217)

References (52)
  • 1
    • 0031798623 scopus 로고    scopus 로고
    • Clinical pharmacology of leukotriene receptor antagonists and 5-lipoxygenase inhibitors
    • Drazen J. Clinical pharmacology of leukotriene receptor antagonists and 5-lipoxygenase inhibitors. Am J Respir Crit Care Med 1998;157:S233-S237.
    • (1998) Am J Respir Crit Care Med , vol.157
    • Drazen, J.1
  • 2
    • 0003662479 scopus 로고    scopus 로고
    • April 1997. Bethesda, MD: U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health, National Heart, Lung, and Blood Institute; Publication No. 97-4051
    • National Asthma Education and Prevention Program. Expert Panel Report 2: guidelines for the diagnosis and management of asthma, April 1997. Bethesda, MD: U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health, National Heart, Lung, and Blood Institute; 1997. Publication No. 97-4051.
    • (1997) Expert Panel Report 2: Guidelines for the Diagnosis and Management of Asthma
  • 3
    • 1542609873 scopus 로고    scopus 로고
    • A review of montelukast in the treatment of asthma and allergic rhinitis
    • Nayak A. A review of montelukast in the treatment of asthma and allergic rhinitis. Expert Opin Pharmacother 2004;5:679-686.
    • (2004) Expert Opin Pharmacother , vol.5 , pp. 679-686
    • Nayak, A.1
  • 5
    • 0033574195 scopus 로고    scopus 로고
    • Oral montelukast, inhaled beclomethasone, and placebo for chronic asthma: A randomized, controlled trial
    • Montelukast/Beclomethasone Study Group
    • Malmstrom K, Rodriguez-Gomez G, Guerra J, Villaran C, Pineiro A, Wei LX, Seidenberg BC, Reiss TF. Oral montelukast, inhaled beclomethasone, and placebo for chronic asthma: a randomized, controlled trial. Montelukast/Beclomethasone Study Group. Ann Intern Med 1999;130:487-495.
    • (1999) Ann Intern Med , vol.130 , pp. 487-495
    • Malmstrom, K.1    Rodriguez-Gomez, G.2    Guerra, J.3    Villaran, C.4    Pineiro, A.5    Wei, L.X.6    Seidenberg, B.C.7    Reiss, T.F.8
  • 8
    • 0034443957 scopus 로고    scopus 로고
    • Heterogeneity of therapeutic responses in asthma
    • Drazen JM, Silverman EK, Lee TH. Heterogeneity of therapeutic responses in asthma. Br Med Bull 2000;56:1054-1070.
    • (2000) Br Med Bull , vol.56 , pp. 1054-1070
    • Drazen, J.M.1    Silverman, E.K.2    Lee, T.H.3
  • 10
    • 32444436999 scopus 로고    scopus 로고
    • Respiratory diseases
    • Thomas S, editor. Kansas City, MO: American College of Clinical Pharmacy
    • Lima JJ, Wang J. Respiratory diseases. In: Thomas S, editor. Pharmacogenomics: applications to patient care. Kansas City, MO: American College of Clinical Pharmacy; 2004. pp. 571-611.
    • (2004) Pharmacogenomics: Applications to Patient Care , pp. 571-611
    • Lima, J.J.1    Wang, J.2
  • 11
    • 20344374952 scopus 로고    scopus 로고
    • The pharmacogenetics of asthma: An update
    • Tantisira KG, Weiss ST. The pharmacogenetics of asthma: an update. Curr Opin Mol Ther 2005;7:209-217.
    • (2005) Curr Opin Mol Ther , vol.7 , pp. 209-217
    • Tantisira, K.G.1    Weiss, S.T.2
  • 14
    • 0033803781 scopus 로고    scopus 로고
    • Variant LTC(4) synthase allele modifies cysteinyl leukotriene synthesis in eosinophils and predicts clinical response to zafirlukast
    • Sampson AP, Siddiqui S, Buchanan D, Howarth PH, Holgate ST, Holloway JW, Sayers I. Variant LTC(4) synthase allele modifies cysteinyl leukotriene synthesis in eosinophils and predicts clinical response to zafirlukast. Thorax 2000;55:S28-S31.
    • (2000) Thorax , vol.55
    • Sampson, A.P.1    Siddiqui, S.2    Buchanan, D.3    Howarth, P.H.4    Holgate, S.T.5    Holloway, J.W.6    Sayers, I.7
  • 15
    • 18644372214 scopus 로고    scopus 로고
    • Leukotriene C4 synthase gene A(-444)C polymorphism and clinical response to a CYS-LT(1) antagonist, pranlukast, in Japanese patients with moderate asthma
    • Asano K, Shiomi T, Hasegawa N, Nakamura H, Kudo H, Matsuzaki T, Hakuno H, Fukunaga K, Suzuki Y, Kanazawa M, et al. Leukotriene C4 synthase gene A(-444)C polymorphism and clinical response to a CYS-LT(1) antagonist, pranlukast, in Japanese patients with moderate asthma. Pharmacogenetics 2002;12:565-570.
    • (2002) Pharmacogenetics , vol.12 , pp. 565-570
    • Asano, K.1    Shiomi, T.2    Hasegawa, N.3    Nakamura, H.4    Kudo, H.5    Matsuzaki, T.6    Hakuno, H.7    Fukunaga, K.8    Suzuki, Y.9    Kanazawa, M.10
  • 16
    • 0142031051 scopus 로고    scopus 로고
    • Effect of montelukast on time-course of exhaled nitric oxide in asthma: Influence of LTC4 synthase A(-444)C polymorphism
    • Whelan GJ, Blake K, Kissoon N, Duckworth LJ, Wang J, Sylvester JE, Lima JJ. Effect of montelukast on time-course of exhaled nitric oxide in asthma: influence of LTC4 synthase A(-444)C polymorphism. Pediatr Pulmonol 2003;36:413-420.
    • (2003) Pediatr Pulmonol , vol.36 , pp. 413-420
    • Whelan, G.J.1    Blake, K.2    Kissoon, N.3    Duckworth, L.J.4    Wang, J.5    Sylvester, J.E.6    Lima, J.J.7
  • 17
    • 0033590513 scopus 로고    scopus 로고
    • Treatment of asthma with drugs modifying the leukotriene pathway
    • Drazen JM, Israel E, O'Byrne PM. Treatment of asthma with drugs modifying the leukotriene pathway. N Engl J Med 1999;340:197-206.
    • (1999) N Engl J Med , vol.340 , pp. 197-206
    • Drazen, J.M.1    Israel, E.2    O'Byrne, P.M.3
  • 18
    • 3242807236 scopus 로고    scopus 로고
    • Cysteinyl leukotrienes and their receptors: Cellular distribution and function in immune and inflammatory responses
    • Kanaoka Y, Boyce JA. Cysteinyl leukotrienes and their receptors: cellular distribution and function in immune and inflammatory responses. J Immunol 2004;173:1503-1510.
    • (2004) J Immunol , vol.173 , pp. 1503-1510
    • Kanaoka, Y.1    Boyce, J.A.2
  • 21
    • 0025164256 scopus 로고
    • Leukotrienes and other products of the 5-lipoxygenase pathway: Biochemistry and relation to pathobiology in human diseases
    • Lewis RA, Austen KF, Soberman RJ. Leukotrienes and other products of the 5-lipoxygenase pathway: biochemistry and relation to pathobiology in human diseases. N Engl J Med 1990;323:645-655.
    • (1990) N Engl J Med , vol.323 , pp. 645-655
    • Lewis, R.A.1    Austen, K.F.2    Soberman, R.J.3
  • 22
    • 0024392871 scopus 로고
    • The identification of a distinct export step following the biosynthesis of leukotriene C4 by human eosinophils
    • Lam BK, Owen WF Jr, Austen KF, Soberman RJ. The identification of a distinct export step following the biosynthesis of leukotriene C4 by human eosinophils. J Biol Chem 1989;264:12885-12889.
    • (1989) J Biol Chem , vol.264 , pp. 12885-12889
    • Lam, B.K.1    Owen Jr., W.F.2    Austen, K.F.3    Soberman, R.J.4
  • 23
    • 0012963984 scopus 로고
    • Interconversion of leukotrienes catalyzed by purified gamma-glutamyl transpeptidase: Concomitant formation of leukotriene D4 and gamma- Glutamyl amino acids
    • Anderson ME, Allison RD, Meister A. Interconversion of leukotrienes catalyzed by purified gamma-glutamyl transpeptidase: concomitant formation of leukotriene D4 and gamma- glutamyl amino acids. Proc Natl Acad Sci USA 1982;79:1088-1091.
    • (1982) Proc Natl Acad Sci USA , vol.79 , pp. 1088-1091
    • Anderson, M.E.1    Allison, R.D.2    Meister, A.3
  • 24
    • 0020646863 scopus 로고
    • Conversion of leukotriene D4 to leukotriene E4 by a dipeptidase released from the specific granule of human polymorphonuclear leucocytes
    • Lee CW, Lewis RA, Corey EJ, Austen KF. Conversion of leukotriene D4 to leukotriene E4 by a dipeptidase released from the specific granule of human polymorphonuclear leucocytes. Immunology 1983;48:27-35.
    • (1983) Immunology , vol.48 , pp. 27-35
    • Lee, C.W.1    Lewis, R.A.2    Corey, E.J.3    Austen, K.F.4
  • 25
    • 0023589276 scopus 로고
    • Leukotrienes and airway responses
    • Drazen JM, Austen KF. Leukotrienes and airway responses. Am Rev Respir Dis 1987;136:985-998.
    • (1987) Am Rev Respir Dis , vol.136 , pp. 985-998
    • Drazen, J.M.1    Austen, K.F.2
  • 26
    • 19044376965 scopus 로고    scopus 로고
    • Cysteinyl leukotrienes in allergic inflammation: Strategic target for therapy
    • Busse W, Kraft M. Cysteinyl leukotrienes in allergic inflammation: strategic target for therapy. Chest 2005;127:1312-1326.
    • (2005) Chest , vol.127 , pp. 1312-1326
    • Busse, W.1    Kraft, M.2
  • 28
    • 0031731716 scopus 로고    scopus 로고
    • Integrating patient preferences into health outcomes assessment: The multi-attribute Asthma Symptom Utility Index
    • Revicki DA, Leidy NK, Brennan-Diemer F, Sorensen S, Togias A. Integrating patient preferences into health outcomes assessment: the multi-attribute Asthma Symptom Utility Index. Chest 1998;114:998-1007.
    • (1998) Chest , vol.114 , pp. 998-1007
    • Revicki, D.A.1    Leidy, N.K.2    Brennan-Diemer, F.3    Sorensen, S.4    Togias, A.5
  • 30
    • 0034658876 scopus 로고    scopus 로고
    • A new MALDI-TOF based mini-sequencing assay for genotyping of SNPS
    • Sun X, Ding H, Hung K, Guo B. A new MALDI-TOF based mini-sequencing assay for genotyping of SNPS. Nucleic Acids Res 2000;28:E68.
    • (2000) Nucleic Acids Res , vol.28
    • Sun, X.1    Ding, H.2    Hung, K.3    Guo, B.4
  • 31
    • 0034117172 scopus 로고    scopus 로고
    • Analysis of single nucleotide polymorphisms by primer extension and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
    • Fei Z, Smith LM. Analysis of single nucleotide polymorphisms by primer extension and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Rapid Commun Mass Spectrom 2000;14:950-959.
    • (2000) Rapid Commun Mass Spectrom , vol.14 , pp. 950-959
    • Fei, Z.1    Smith, L.M.2
  • 32
    • 0035068527 scopus 로고    scopus 로고
    • High-throughput multiplex SNP genotyping with MALDI-TOF mass spectrometry: Practice, problems and promise
    • Bray MS, Boerwinkle E, Doris PA. High-throughput multiplex SNP genotyping with MALDI-TOF mass spectrometry: practice, problems and promise. Hum Mutat 2001;17:296-304.
    • (2001) Hum Mutat , vol.17 , pp. 296-304
    • Bray, M.S.1    Boerwinkle, E.2    Doris, P.A.3
  • 34
    • 0033794938 scopus 로고    scopus 로고
    • Accuracy of haplotype frequency estimation for biallelic loci, via the expectation-maximization algorithm for unphased diploid genotype data
    • Fallin D, Schork NJ. Accuracy of haplotype frequency estimation for biallelic loci, via the expectation-maximization algorithm for unphased diploid genotype data. Am J Hum Genet 2000;67:947-959.
    • (2000) Am J Hum Genet , vol.67 , pp. 947-959
    • Fallin, D.1    Schork, N.J.2
  • 35
    • 0035154452 scopus 로고    scopus 로고
    • Genetic analysis of case/control data using estimated haplotype frequencies: Application to APOE locus variation and Alzheimer's disease
    • Fallin D, Cohen A, Essioux L, Chumakov I, Blumenfeld M, Cohen D, Schork NJ. Genetic analysis of case/control data using estimated haplotype frequencies: application to APOE locus variation and Alzheimer's disease. Genome Res 2001;11:143-151.
    • (2001) Genome Res , vol.11 , pp. 143-151
    • Fallin, D.1    Cohen, A.2    Essioux, L.3    Chumakov, I.4    Blumenfeld, M.5    Cohen, D.6    Schork, N.J.7
  • 36
    • 0033358548 scopus 로고    scopus 로고
    • Use of unlinked genetic markers to detect population stratification in association studies
    • Pritchard JK, Rosenberg NA. Use of unlinked genetic markers to detect population stratification in association studies. Am J Hum Genet 1999;65:220-228.
    • (1999) Am J Hum Genet , vol.65 , pp. 220-228
    • Pritchard, J.K.1    Rosenberg, N.A.2
  • 38
    • 0042121509 scopus 로고    scopus 로고
    • Promoter polymorphism in the 5-lipoxygenase (ALOX5) and 5-lipoxygenase-activating protein (ALOX5AP) genes and asthma susceptibility in a Caucasian population
    • Sayers I, Barton S, Rorke S, Sawyer J, Peng Q, Beghe B, Ye S, Keith T, Clough JB, Holloway JW, et al. Promoter polymorphism in the 5-lipoxygenase (ALOX5) and 5-lipoxygenase-activating protein (ALOX5AP) genes and asthma susceptibility in a Caucasian population. Clin Exp Allergy 2003;33:1103-1110.
    • (2003) Clin Exp Allergy , vol.33 , pp. 1103-1110
    • Sayers, I.1    Barton, S.2    Rorke, S.3    Sawyer, J.4    Peng, Q.5    Beghe, B.6    Ye, S.7    Keith, T.8    Clough, J.B.9    Holloway, J.W.10
  • 41
    • 11344267023 scopus 로고    scopus 로고
    • Uncertain biological relevance of polymorphism of leukotriene C4 synthase in asthma
    • Currie GP, Lee D. Uncertain biological relevance of polymorphism of leukotriene C4 synthase in asthma. J Allergy Clin Immunol 2005;115:205.
    • (2005) J Allergy Clin Immunol , vol.115 , pp. 205
    • Currie, G.P.1    Lee, D.2
  • 42
    • 20044382851 scopus 로고    scopus 로고
    • Polymorphism of tandem repeat in promoter of 5-lipoxygenase in ASA-intolerant asthma: A positive association with airway hyperresponsiveness
    • Kim SH, Bae JS, Suh CH, Nahm DH, Holloway JW, Park HS. Polymorphism of tandem repeat in promoter of 5-lipoxygenase in ASA-intolerant asthma: a positive association with airway hyperresponsiveness. Allergy 2005;60:760-765.
    • (2005) Allergy , vol.60 , pp. 760-765
    • Kim, S.H.1    Bae, J.S.2    Suh, C.H.3    Nahm, D.H.4    Holloway, J.W.5    Park, H.S.6
  • 43
    • 0033827946 scopus 로고    scopus 로고
    • Enhanced expression of the leukotriene C(4) synthase due to overactive transcription of an allelic variant associated with aspirin-intolerant asthma
    • Sanak M, Pierzchalska M, Bazan-Socha S, Szczeklik A. Enhanced expression of the leukotriene C(4) synthase due to overactive transcription of an allelic variant associated with aspirin-intolerant asthma. Am J Respir Cell Mol Biol 2000;23:290-296.
    • (2000) Am J Respir Cell Mol Biol , vol.23 , pp. 290-296
    • Sanak, M.1    Pierzchalska, M.2    Bazan-Socha, S.3    Szczeklik, A.4
  • 44
    • 0034099760 scopus 로고    scopus 로고
    • Structure, function, and regulation of leukotriene A4 hydrolase
    • Haeggstrom JZ. Structure, function, and regulation of leukotriene A4 hydrolase. Am J Respir Crit Care Med 2000;161:S25-S31.
    • (2000) Am J Respir Crit Care Med , vol.161
    • Haeggstrom, J.Z.1
  • 45
    • 0019311062 scopus 로고
    • Leukotriene B, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes
    • Ford-Hutchinson AW, Bray MA, Doig MV, Shipley ME, Smith MJ. Leukotriene B, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes. Nature 1980;286:264-265.
    • (1980) Nature , vol.286 , pp. 264-265
    • Ford-Hutchinson, A.W.1    Bray, M.A.2    Doig, M.V.3    Shipley, M.E.4    Smith, M.J.5
  • 46
    • 2342543199 scopus 로고    scopus 로고
    • Leukotrienes and atherosclerosis: New roles for old mediators
    • Jala VR, Haribabu B. Leukotrienes and atherosclerosis: new roles for old mediators. Trends Immunol 2004;25:315-322.
    • (2004) Trends Immunol , vol.25 , pp. 315-322
    • Jala, V.R.1    Haribabu, B.2
  • 47
    • 0032781499 scopus 로고    scopus 로고
    • Enhanced transport of anticancer agents and leukotriene C4 by the human canalicular multispecific organic anion transporter (cMOAT/MRP2)
    • Kawabe T, Chen ZS, Wada M, Uchiumi T, Ono M, Akiyama S, Kuwano M. Enhanced transport of anticancer agents and leukotriene C4 by the human canalicular multispecific organic anion transporter (cMOAT/MRP2). FEBS Lett 1999;456:327-331.
    • (1999) FEBS Lett , vol.456 , pp. 327-331
    • Kawabe, T.1    Chen, Z.S.2    Wada, M.3    Uchiumi, T.4    Ono, M.5    Akiyama, S.6    Kuwano, M.7
  • 48
    • 0031893212 scopus 로고    scopus 로고
    • Different pattern of MRP localization in ciliated and basal cells from human bronchial epithelium
    • Brechot JM, Hurbain I, Fajac A, Daty N, Bernaudin JF. Different pattern of MRP localization in ciliated and basal cells from human bronchial epithelium. J Histochem Cytochem 1998;46:513-517.
    • (1998) J Histochem Cytochem , vol.46 , pp. 513-517
    • Brechot, J.M.1    Hurbain, I.2    Fajac, A.3    Daty, N.4    Bernaudin, J.F.5
  • 49
    • 0036246271 scopus 로고    scopus 로고
    • Identification of 779 genetic variations in eight genes encoding members of the ATP-binding cassette, subfamily C (ABCC/ MRP/CFTR)
    • Saito S, Iida A, Sekine A, Miura Y, Ogawa C, Kawauchi S, Higuchi S, Nakamura Y. Identification of 779 genetic variations in eight genes encoding members of the ATP-binding cassette, subfamily C (ABCC/ MRP/CFTR). J Hum Genet 2002;47:147-171.
    • (2002) J Hum Genet , vol.47 , pp. 147-171
    • Saito, S.1    Iida, A.2    Sekine, A.3    Miura, Y.4    Ogawa, C.5    Kawauchi, S.6    Higuchi, S.7    Nakamura, Y.8
  • 51
    • 0035103009 scopus 로고    scopus 로고
    • Polymorphism of the ABC transporter genes, MDR1, MRP1 and MRP2/cMOAT, in healthy Japanese subjects
    • Ito S, Ieiri I, Tanabe M, Suzuki A, Higuchi S, Otsubo K. Polymorphism of the ABC transporter genes, MDR1, MRP1 and MRP2/cMOAT, in healthy Japanese subjects. Pharmacogenetics 2001;11:175-184.
    • (2001) Pharmacogenetics , vol.11 , pp. 175-184
    • Ito, S.1    Ieiri, I.2    Tanabe, M.3    Suzuki, A.4    Higuchi, S.5    Otsubo, K.6
  • 52
    • 13144306071 scopus 로고    scopus 로고
    • Genome-wide association studies for common diseases and complex traits
    • Hirschhorn JN, Daly MJ. Genome-wide association studies for common diseases and complex traits. Nat Rev Genet 2005;6:95-108.
    • (2005) Nat Rev Genet , vol.6 , pp. 95-108
    • Hirschhorn, J.N.1    Daly, M.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.