-
1
-
-
77950944395
-
Macrophages, innate immunity and cancer: Balance, tolerance, and diversity
-
Mantovani A, Sica A (2010) Macrophages, innate immunity and cancer: balance, tolerance, and diversity. Curr Opin Immunol 22:231-237
-
(2010)
Curr Opin Immunol
, vol.22
, pp. 231-237
-
-
Mantovani, A.1
Sica, A.2
-
2
-
-
34547121206
-
Hypoxia in cancer: Significance and impact on clinical outcome
-
Vaupel P, Mayer A (2007) Hypoxia in cancer: significance and impact on clinical outcome. Cancer Metastasis Rev 26:225-239
-
(2007)
Cancer Metastasis Rev
, vol.26
, pp. 225-239
-
-
Vaupel, P.1
Mayer, A.2
-
4
-
-
77957735624
-
Role of tumour-associated macrophages in cancerrelated inflammation
-
Sica A (2010) Role of tumour-associated macrophages in cancerrelated inflammation. Exp Oncol 32:153-158
-
(2010)
Exp Oncol
, vol.32
, pp. 153-158
-
-
Sica, A.1
-
5
-
-
24944587964
-
Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors
-
De Palma M, Venneri MA, Galli R, Sergi Sergi L, Politi LS, Sampaolesi M, Naldini L (2005) Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors. Cancer Cell 8:211-226
-
(2005)
Cancer Cell
, vol.8
, pp. 211-226
-
-
De Palma, M.1
Venneri, M.A.2
Galli, R.3
Sergi Sergi, L.4
Politi, L.S.5
Sampaolesi, M.6
Naldini, L.7
-
6
-
-
34248172324
-
Altered macrophage differentiation and immune dysfunction in tumor development
-
Sica A, Bronte V (2007) Altered macrophage differentiation and immune dysfunction in tumor development. J Clin Invest 117:1155-1166
-
(2007)
J Clin Invest
, vol.117
, pp. 1155-1166
-
-
Sica, A.1
Bronte, V.2
-
7
-
-
69249222379
-
Polarization of tumorassociated neutrophil phenotype by TGF-beta: "N1" versus "N2" TAN
-
Fridlender ZG, Sun J, Kim S, Kapoor V, Cheng G, Ling L, Worthen GS, Albelda SM (2009) Polarization of tumorassociated neutrophil phenotype by TGF-beta: "N1" versus "N2" TAN. Cancer Cell 16:183-194
-
(2009)
Cancer Cell
, vol.16
, pp. 183-194
-
-
Fridlender, Z.G.1
Sun, J.2
Kim, S.3
Kapoor, V.4
Cheng, G.5
Ling, L.6
Worthen, G.S.7
Albelda, S.M.8
-
8
-
-
0034624828
-
A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
-
Akashi K, Traver D, Miyamoto T, Weissman IL (2000) A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature 404:193-197
-
(2000)
Nature
, vol.404
, pp. 193-197
-
-
Akashi, K.1
Traver, D.2
Miyamoto, T.3
Weissman, I.L.4
-
9
-
-
65049084189
-
Tumor-associated macrophages and the related myeloid-derived suppressor cells as a paradigm of the diversity of macrophage activation
-
Mantovani A, Sica A, Allavena P, Garlanda C, Locati M (2009) Tumor-associated macrophages and the related myeloid-derived suppressor cells as a paradigm of the diversity of macrophage activation. Hum Immunol 70:325-330
-
(2009)
Hum Immunol
, vol.70
, pp. 325-330
-
-
Mantovani, A.1
Sica, A.2
Allavena, P.3
Garlanda, C.4
Locati, M.5
-
11
-
-
53549126347
-
The Janus face of dendritic cells in cancer
-
Chaput N, Conforti R, Viaud S, Spatz A, Zitvogel L (2008) The Janus face of dendritic cells in cancer. Oncogene 27:5920-5931
-
(2008)
Oncogene
, vol.27
, pp. 5920-5931
-
-
Chaput, N.1
Conforti, R.2
Viaud, S.3
Spatz, A.4
Zitvogel, L.5
-
12
-
-
79951673773
-
The dendritic cell-tumor cross-talk in cancer
-
Ma Y, Aymeric L, Locher C, Kroemer G, Zitvogel L (2011) The dendritic cell-tumor cross-talk in cancer. Curr Opin Immunol 23:146-152
-
(2011)
Curr Opin Immunol
, vol.23
, pp. 146-152
-
-
Ma, Y.1
Aymeric, L.2
Locher, C.3
Kroemer, G.4
Zitvogel, L.5
-
13
-
-
77956976681
-
Macrophage plasticity and interaction with lymphocyte subsets: Cancer as a paradigm
-
Biswas SK, Mantovani A (2010) Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm. Nat Immunol 11:889-896
-
(2010)
Nat Immunol
, vol.11
, pp. 889-896
-
-
Biswas, S.K.1
Mantovani, A.2
-
14
-
-
0020586345
-
Regulation of the macrophage content of neoplasms by chemoattractants
-
Bottazzi B, Polentarutti N, Acero R, Balsari A, Boraschi D, Ghezzi P, Salmona M, Mantovani A (1983) Regulation of the macrophage content of neoplasms by chemoattractants. Science 220:210-212
-
(1983)
Science
, vol.220
, pp. 210-212
-
-
Bottazzi, B.1
Polentarutti, N.2
Acero, R.3
Balsari, A.4
Boraschi, D.5
Ghezzi, P.6
Salmona, M.7
Mantovani, A.8
-
15
-
-
0347123433
-
Tumour-educated macrophages promote tumour progression and metastasis
-
Pollard JW (2004) Tumour-educated macrophages promote tumour progression and metastasis. Nat Rev Cancer 4:71-78
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 71-78
-
-
Pollard, J.W.1
-
16
-
-
40049088602
-
The inflammatory micro-environment in tumor progression: The role of tumor-associated macrophages
-
Allavena P, Sica A, Solinas G, Porta C, Mantovani A (2008) The inflammatory micro-environment in tumor progression: the role of tumor-associated macrophages. Crit Rev Oncol Hematol 66:1-9
-
(2008)
Crit Rev Oncol Hematol
, vol.66
, pp. 1-9
-
-
Allavena, P.1
Sica, A.2
Solinas, G.3
Porta, C.4
Mantovani, A.5
-
17
-
-
0030014168
-
Macrophage inflammatory protein-1 alpha expression in nonneoplastic and neoplastic lung tissue
-
Konishi T, Okabe H, Katoh H, Fujiyama Y, Mori A (1996) Macrophage inflammatory protein-1 alpha expression in nonneoplastic and neoplastic lung tissue. Virchows Arch 428:107-111
-
(1996)
Virchows Arch
, vol.428
, pp. 107-111
-
-
Konishi, T.1
Okabe, H.2
Katoh, H.3
Fujiyama, Y.4
Mori, A.5
-
18
-
-
10744219598
-
Regulation of the chemokine receptor CXCR4 by hypoxia
-
Schioppa T, Uranchimeg B, Saccani A, Biswas SK, Doni A, Rapisarda A, Bernasconi S, Saccani S, Nebuloni M, Vago L, Mantovani A, Melillo G, Sica A (2003) Regulation of the chemokine receptor CXCR4 by hypoxia. J Exp Med 198:1391-1402
-
(2003)
J Exp Med
, vol.198
, pp. 1391-1402
-
-
Schioppa, T.1
Uranchimeg, B.2
Saccani, A.3
Biswas, S.K.4
Doni, A.5
Rapisarda, A.6
Bernasconi, S.7
Saccani, S.8
Nebuloni, M.9
Vago, L.10
Mantovani, A.11
Melillo, G.12
Sica, A.13
-
19
-
-
3042822267
-
Cancer and the chemokine network
-
Balkwill F (2004) Cancer and the chemokine network. Nat Rev Cancer 4:540-550
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 540-550
-
-
Balkwill, F.1
-
20
-
-
78650996236
-
Activation of urokinase plasminogen activator and its receptor axis is essential for macrophage infiltration in a prostate cancer mouse model
-
Zhang J, Sud S, Mizutani K, Gyetko MR, Pienta KJ (2011) Activation of urokinase plasminogen activator and its receptor axis is essential for macrophage infiltration in a prostate cancer mouse model. Neoplasia 13:23-30
-
(2011)
Neoplasia
, vol.13
, pp. 23-30
-
-
Zhang, J.1
Sud, S.2
Mizutani, K.3
Gyetko, M.R.4
Pienta, K.J.5
-
21
-
-
63049104211
-
Microenvironmental regulation of metastasis
-
Joyce JA, Pollard JW (2009) Microenvironmental regulation of metastasis. Nat Rev Cancer 9:239-252
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 239-252
-
-
Joyce, J.A.1
Pollard, J.W.2
-
23
-
-
77956209435
-
An antimicrobial peptide regulates tumor-associated macrophage trafficking via the chemokine receptor CCR2, a model for tumorigenesis
-
Jin G, Kawsar HI, Hirsch SA, Zeng C, Jia X, Feng Z, Ghosh SK, Zheng QY, Zhou A, McIntyre TM, Weinberg A (2010) An antimicrobial peptide regulates tumor-associated macrophage trafficking via the chemokine receptor CCR2, a model for tumorigenesis. PLoS ONE 5:e10993
-
(2010)
PLoS ONE
, vol.5
-
-
Jin, G.1
Kawsar, H.I.2
Hirsch, S.A.3
Zeng, C.4
Jia, X.5
Feng, Z.6
Ghosh, S.K.7
Zheng, Q.Y.8
Zhou, A.9
McIntyre, T.M.10
Weinberg, A.11
-
24
-
-
34249791475
-
Expression of Tie-2 by human monocytes and their responses to angiopoietin-2
-
Murdoch C, Tazzyman S, Webster S, Lewis CE (2007) Expression of Tie-2 by human monocytes and their responses to angiopoietin-2. J Immunol 178:7405-7411
-
(2007)
J Immunol
, vol.178
, pp. 7405-7411
-
-
Murdoch, C.1
Tazzyman, S.2
Webster, S.3
Lewis, C.E.4
-
25
-
-
34249979533
-
Identification of proangiogenic TIE2-expressing monocytes (TEMs) in human peripheral blood and cancer
-
Venneri MA, De Palma M, Ponzoni M, Pucci F, Scielzo C, Zonari E, Mazzieri R, Doglioni C, Naldini L (2007) Identification of proangiogenic TIE2-expressing monocytes (TEMs) in human peripheral blood and cancer. Blood 109:5276-5285
-
(2007)
Blood
, vol.109
, pp. 5276-5285
-
-
Venneri, M.A.1
De Palma, M.2
Ponzoni, M.3
Pucci, F.4
Scielzo, C.5
Zonari, E.6
Mazzieri, R.7
Doglioni, C.8
Naldini, L.9
-
26
-
-
79955517032
-
TIE2-expressing macrophages limit the therapeutic efficacy of the vascular-disrupting agent combretastatin A4 phosphate in mice
-
Welford AF, Biziato D, Coffelt SB, Nucera S, Fisher M, Pucci F, Serio CD, Naldini L, Palma MD, Tozer GM, Lewis CE (2011) TIE2-expressing macrophages limit the therapeutic efficacy of the vascular-disrupting agent combretastatin A4 phosphate in mice. J Clin Investig
-
(2011)
J Clin Investig
-
-
Welford, A.F.1
Biziato, D.2
Coffelt, S.B.3
Nucera, S.4
Fisher, M.5
Pucci, F.6
Serio, C.D.7
Naldini, L.8
Palma, M.D.9
Tozer, G.M.10
Lewis, C.E.11
-
27
-
-
47049126742
-
Chemokine-mediated rapid turnover of myeloid-derived suppressor cells in tumor-bearing mice
-
Sawanobori Y, Ueha S, Kurachi M, Shimaoka T, Talmadge JE, Abe J, Shono Y, Kitabatake M, Kakimi K, Mukaida N, Matsushima K (2008) Chemokine-mediated rapid turnover of myeloid-derived suppressor cells in tumor-bearing mice. Blood 111:5457-5466
-
(2008)
Blood
, vol.111
, pp. 5457-5466
-
-
Sawanobori, Y.1
Ueha, S.2
Kurachi, M.3
Shimaoka, T.4
Talmadge, J.E.5
Abe, J.6
Shono, Y.7
Kitabatake, M.8
Kakimi, K.9
Mukaida, N.10
Matsushima, K.11
-
28
-
-
54549109936
-
Modulation of the antitumor immune response by complement
-
Markiewski MM, DeAngelis RA, Benencia F, Ricklin-Lichtsteiner SK, Koutoulaki A, Gerard C, Coukos G, Lambris JD (2008) Modulation of the antitumor immune response by complement. Nat Immunol 9:1225-1235
-
(2008)
Nat Immunol
, vol.9
, pp. 1225-1235
-
-
Markiewski, M.M.1
DeAngelis, R.A.2
Benencia, F.3
Ricklin-Lichtsteiner, S.K.4
Koutoulaki, A.5
Gerard, C.6
Coukos, G.7
Lambris, J.D.8
-
29
-
-
53349099219
-
Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein
-
Cheng P, Corzo CA, Luetteke N, Yu B, Nagaraj S, Bui MM, Ortiz M, Nacken W, Sorg C, Vogl T, Roth J, Gabrilovich DI (2008) Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein. J Exp Med 205:2235-2249
-
(2008)
J Exp Med
, vol.205
, pp. 2235-2249
-
-
Cheng, P.1
Corzo, C.A.2
Luetteke, N.3
Yu, B.4
Nagaraj, S.5
Bui, M.M.6
Ortiz, M.7
Nacken, W.8
Sorg, C.9
Vogl, T.10
Roth, J.11
Gabrilovich, D.I.12
-
30
-
-
53349125963
-
Proinflammatory S100 proteins regulate the accumulation of myeloid-derived suppressor cells
-
Sinha P, Okoro C, Foell D, Freeze HH, Ostrand-Rosenberg S, Srikrishna G (2008) Proinflammatory S100 proteins regulate the accumulation of myeloid-derived suppressor cells. J Immunol 181:4666-4675
-
(2008)
J Immunol
, vol.181
, pp. 4666-4675
-
-
Sinha, P.1
Okoro, C.2
Foell, D.3
Freeze, H.H.4
Ostrand-Rosenberg, S.5
Srikrishna, G.6
-
31
-
-
0031975315
-
Neutrophil alveolitis in bronchioloalveolar carcinoma: Induction by tumor-derived interleukin-8 and relation to clinical outcome
-
Bellocq A, Antoine M, Flahault A, Philippe C, Crestani B, Bernaudin JF, Mayaud C, Milleron B, Baud L, Cadranel J (1998) Neutrophil alveolitis in bronchioloalveolar carcinoma: induction by tumor-derived interleukin-8 and relation to clinical outcome. Am J Pathol 152:83-92
-
(1998)
Am J Pathol
, vol.152
, pp. 83-92
-
-
Bellocq, A.1
Antoine, M.2
Flahault, A.3
Philippe, C.4
Crestani, B.5
Bernaudin, J.F.6
Mayaud, C.7
Milleron, B.8
Baud, L.9
Cadranel, J.10
-
33
-
-
28544446111
-
Monocyte and macrophage heterogeneity
-
Gordon S, Taylor PR (2005) Monocyte and macrophage heterogeneity. Nat Rev Immunol 5:953-964
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 953-964
-
-
Gordon, S.1
Taylor, P.R.2
-
34
-
-
0026762988
-
Interleukin 4 potently enhances murine macrophage mannose receptor activity: A marker of alternative immunologic macrophage activation
-
Stein M, Keshav S, Harris N, Gordon S (1992) Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation. J Exp Med 176:287-292
-
(1992)
J Exp Med
, vol.176
, pp. 287-292
-
-
Stein, M.1
Keshav, S.2
Harris, N.3
Gordon, S.4
-
35
-
-
0036839143
-
Macrophage polarization: Tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
-
Mantovani A, Sozzani S, Locati M, Allavena P, Sica A (2002) Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol 23:549-555
-
(2002)
Trends Immunol
, vol.23
, pp. 549-555
-
-
Mantovani, A.1
Sozzani, S.2
Locati, M.3
Allavena, P.4
Sica, A.5
-
36
-
-
56749174940
-
Exploring the full spectrum of macrophage activation
-
Mosser DM, Edwards JP (2008) Exploring the full spectrum of macrophage activation. Nat Rev Immunol 8:958-969
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 958-969
-
-
Mosser, D.M.1
Edwards, J.P.2
-
37
-
-
45549109370
-
Activation of a TGF-beta-specific multistep gene expression program in mature macrophages requires glucocorticoid-mediated surface expression of TGF-beta receptor II
-
Gratchev A, Kzhyshkowska J, Kannookadan S, Ochsenreiter M, Popova A, Yu X, Mamidi S, Stonehouse-Usselmann E, Muller-Molinet I, Gooi L, Goerdt S (2008) Activation of a TGF-beta-specific multistep gene expression program in mature macrophages requires glucocorticoid-mediated surface expression of TGF-beta receptor II. J Immunol 180:6553-6565
-
(2008)
J Immunol
, vol.180
, pp. 6553-6565
-
-
Gratchev, A.1
Kzhyshkowska, J.2
Kannookadan, S.3
Ochsenreiter, M.4
Popova, A.5
Yu, X.6
Mamidi, S.7
Stonehouse-Usselmann, E.8
Muller-Molinet, I.9
Gooi, L.10
Goerdt, S.11
-
38
-
-
55349128861
-
Integrated regulation of Toll-like receptor responses by Notch and interferon-gamma pathways
-
Hu X, Chung AY, Wu I, Foldi J, Chen J, Ji JD, Tateya T, Kang YJ, Han J, Gessler M, Kageyama R, Ivashkiv LB (2008) Integrated regulation of Toll-like receptor responses by Notch and interferon-gamma pathways. Immunity 29:691-703
-
(2008)
Immunity
, vol.29
, pp. 691-703
-
-
Hu, X.1
Chung, A.Y.2
Wu, I.3
Foldi, J.4
Chen, J.5
Ji, J.D.6
Tateya, T.7
Kang, Y.J.8
Han, J.9
Gessler, M.10
Kageyama, R.11
Ivashkiv, L.B.12
-
39
-
-
0036134881
-
Generation of diversity in the innate immune system: Macrophage heterogeneity arises from gene-autonomous transcriptional probability of individual inducible genes
-
Ravasi T, Wells C, Forest A, Underhill DM, Wainwright BJ, Aderem A, Grimmond S, Hume DA (2002) Generation of diversity in the innate immune system: macrophage heterogeneity arises from gene-autonomous transcriptional probability of individual inducible genes. J Immunol 168:44-50
-
(2002)
J Immunol
, vol.168
, pp. 44-50
-
-
Ravasi, T.1
Wells, C.2
Forest, A.3
Underhill, D.M.4
Wainwright, B.J.5
Aderem, A.6
Grimmond, S.7
Hume, D.A.8
-
40
-
-
0029450412
-
Signalling heterogeneity as a contributing factor in macrophage functional diversity
-
Riches DW (1995) Signalling heterogeneity as a contributing factor in macrophage functional diversity. Semin Cell Biol 6:377-384
-
(1995)
Semin Cell Biol
, vol.6
, pp. 377-384
-
-
Riches, D.W.1
-
41
-
-
0023711482
-
Differential regulation of gene expression during macrophage activation with a polyribonucleotide. The role of endogenously derived IFN
-
Riches DW, Henson PM, Remigio LK, Catterall JF, Strunk RC (1988) Differential regulation of gene expression during macrophage activation with a polyribonucleotide. The role of endogenously derived IFN. J Immunol 141:180-188
-
(1988)
J Immunol
, vol.141
, pp. 180-188
-
-
Riches, D.W.1
Henson, P.M.2
Remigio, L.K.3
Catterall, J.F.4
Strunk, R.C.5
-
42
-
-
21244443731
-
Macrophages sequentially change their functional phenotype in response to changes in microenvironmental influences
-
Stout RD, Jiang C, Matta B, Tietzel I, Watkins SK, Suttles J (2005) Macrophages sequentially change their functional phenotype in response to changes in microenvironmental influences. J Immunol 175:342-349
-
(2005)
J Immunol
, vol.175
, pp. 342-349
-
-
Stout, R.D.1
Jiang, C.2
Matta, B.3
Tietzel, I.4
Watkins, S.K.5
Suttles, J.6
-
43
-
-
0023926946
-
Characterization of lipopolysaccharide-induced macrophage gene expression
-
Tannenbaum CS, Koerner TJ, Jansen MM, Hamilton TA (1988) Characterization of lipopolysaccharide-induced macrophage gene expression. J Immunol 140:3640-3645
-
(1988)
J Immunol
, vol.140
, pp. 3640-3645
-
-
Tannenbaum, C.S.1
Koerner, T.J.2
Jansen, M.M.3
Hamilton, T.A.4
-
44
-
-
38449093322
-
Tuning' of type I interferon-induced Jak-STAT1 signaling by calciumdependent kinases in macrophages
-
Wang L, Tassiulas I, Park-Min KH, Reid AC, Gil-Henn H, Schlessinger J, Baron R, Zhang JJ, Ivashkiv LB (2008) 'Tuning' of type I interferon-induced Jak-STAT1 signaling by calciumdependent kinases in macrophages. Nat Immunol 9:186-193
-
(2008)
Nat Immunol
, vol.9
, pp. 186-193
-
-
Wang, L.1
Tassiulas, I.2
Park-Min, K.H.3
Reid, A.C.4
Gil-Henn, H.5
Schlessinger, J.6
Baron, R.7
Zhang, J.J.8
Ivashkiv, L.B.9
-
45
-
-
0037963473
-
Blood monocytes consist of two principal subsets with distinct migratory properties
-
Geissmann F, Jung S, Littman DR (2003) Blood monocytes consist of two principal subsets with distinct migratory properties. Immunity 19:71-82
-
(2003)
Immunity
, vol.19
, pp. 71-82
-
-
Geissmann, F.1
Jung, S.2
Littman, D.R.3
-
46
-
-
69249208488
-
NFkappaB and phosphatidylinositol 3-kinase activity mediates the HCMV-induced atypical M1/M2 polarization of monocytes
-
Chan G, Bivins-Smith ER, Smith MS, Yurochko AD (2009) NFkappaB and phosphatidylinositol 3-kinase activity mediates the HCMV-induced atypical M1/M2 polarization of monocytes. Virus Res 144:329-333
-
(2009)
Virus Res
, vol.144
, pp. 329-333
-
-
Chan, G.1
Bivins-Smith, E.R.2
Smith, M.S.3
Yurochko, A.D.4
-
47
-
-
47949091727
-
Transcriptome analysis reveals human cytomegalovirus reprograms monocyte differentiation toward an M1 macrophage
-
Chan G, Bivins-Smith ER, Smith MS, Smith PM, Yurochko AD (2008) Transcriptome analysis reveals human cytomegalovirus reprograms monocyte differentiation toward an M1 macrophage. J Immunol 181:698-711
-
(2008)
J Immunol
, vol.181
, pp. 698-711
-
-
Chan, G.1
Bivins-Smith, E.R.2
Smith, M.S.3
Smith, P.M.4
Yurochko, A.D.5
-
48
-
-
77951822653
-
Dynamic, M2-like remodeling phenotypes of CD11c + adipose tissue macrophages during high-fat diet-induced obesity in mice
-
Shaul ME, Bennett G, Strissel KJ, Greenberg AS, Obin MS. Dynamic, M2-like remodeling phenotypes of CD11c + adipose tissue macrophages during high-fat diet-induced obesity in mice. Diabetes 59:1171-1181
-
Diabetes
, vol.59
, pp. 1171-1181
-
-
Shaul, M.E.1
Bennett, G.2
Strissel, K.J.3
Greenberg, A.S.4
Obin, M.S.5
-
49
-
-
70349559403
-
Endotoxin tolerance: New mechanisms, molecules and clinical significance
-
Biswas SK, Lopez-Collazo E (2009) Endotoxin tolerance: new mechanisms, molecules and clinical significance. Trends Immunol 30:475-487
-
(2009)
Trends Immunol
, vol.30
, pp. 475-487
-
-
Biswas, S.K.1
Lopez-Collazo, E.2
-
50
-
-
42149099408
-
Plasticity of macrophage function during tumor progression: Regulation by distinct molecular mechanisms
-
Biswas SK, Sica A, Lewis CE (2008) Plasticity of macrophage function during tumor progression: regulation by distinct molecular mechanisms. J Immunol 180:2011-2017
-
(2008)
J Immunol
, vol.180
, pp. 2011-2017
-
-
Biswas, S.K.1
Sica, A.2
Lewis, C.E.3
-
51
-
-
33846026712
-
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
-
Lumeng CN, Bodzin JL, Saltiel AR (2007) Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J Clin Invest 117:175-184
-
(2007)
J Clin Invest
, vol.117
, pp. 175-184
-
-
Lumeng, C.N.1
Bodzin, J.L.2
Saltiel, A.R.3
-
52
-
-
0029913684
-
The altered tumoricidal capacity of macrophages isolated from tumorbearing mice is related to reduce expression of the inducible nitric oxide synthase gene
-
Dinapoli MR, Calderon CL, Lopez DM (1996) The altered tumoricidal capacity of macrophages isolated from tumorbearing mice is related to reduce expression of the inducible nitric oxide synthase gene. J Exp Med 183:1323-1329
-
(1996)
J Exp Med
, vol.183
, pp. 1323-1329
-
-
Dinapoli, M.R.1
Calderon, C.L.2
Lopez, D.M.3
-
53
-
-
0034650833
-
Autocrine production of IL-10 mediates defective IL-12 production and NF-kappa B activation in tumor-associated macrophages
-
Sica A, Saccani A, Bottazzi B, Polentarutti N, Vecchi A, van Damme J, Mantovani A (2000) Autocrine production of IL- 10 mediates defective IL-12 production and NF-kappa B activation in tumor-associated macrophages. J Immunol 164:762-767
-
(2000)
J Immunol
, vol.164
, pp. 762-767
-
-
Sica, A.1
Saccani, A.2
Bottazzi, B.3
Polentarutti, N.4
Vecchi, A.5
Van Damme, J.6
Mantovani, A.7
-
54
-
-
33845752914
-
P50 nuclear factor-kappaB overexpression in tumor-associated macrophages inhibits M1 inflammatory responses and antitumor resistance
-
Saccani A, Schioppa T, Porta C, Biswas SK, Nebuloni M, Vago L, Bottazzi B, Colombo MP, Mantovani A, Sica A (2006) p50 nuclear factor-kappaB overexpression in tumor-associated macrophages inhibits M1 inflammatory responses and antitumor resistance. Cancer Res 66:11432-11440
-
(2006)
Cancer Res
, vol.66
, pp. 11432-11440
-
-
Saccani, A.1
Schioppa, T.2
Porta, C.3
Biswas, S.K.4
Nebuloni, M.5
Vago, L.6
Bottazzi, B.7
Colombo, M.P.8
Mantovani, A.9
Sica, A.10
-
55
-
-
48349102876
-
Macrophage polarization in tumour progression
-
Sica A, Larghi P, Mancino A, Rubino L, Porta C, Totaro MG, Rimoldi M, Biswas SK, Allavena P, Mantovani A (2008) Macrophage polarization in tumour progression. Semin Cancer Biol 18:349-355
-
(2008)
Semin Cancer Biol
, vol.18
, pp. 349-355
-
-
Sica, A.1
Larghi, P.2
Mancino, A.3
Rubino, L.4
Porta, C.5
Totaro, M.G.6
Rimoldi, M.7
Biswas, S.K.8
Allavena, P.9
Mantovani, A.10
-
56
-
-
46949110502
-
Tumor angiogenesis and progression are enhanced by Sema4D produced by tumorassociated macrophages
-
Sierra JR, Corso S, Caione L, Cepero V, Conrotto P, Cignetti A, Piacibello W, Kumanogoh A, Kikutani H, Comoglio PM, Tamagnone L, Giordano S (2008) Tumor angiogenesis and progression are enhanced by Sema4D produced by tumorassociated macrophages. J Exp Med 205:1673-1685
-
(2008)
J Exp Med
, vol.205
, pp. 1673-1685
-
-
Sierra, J.R.1
Corso, S.2
Caione, L.3
Cepero, V.4
Conrotto, P.5
Cignetti, A.6
Piacibello, W.7
Kumanogoh, A.8
Kikutani, H.9
Comoglio, P.M.10
Tamagnone, L.11
Giordano, S.12
-
57
-
-
77950422149
-
Malignant cells fuel tumor growth by educating infiltrating leukocytes to produce the mitogen Gas6
-
Loges S, Schmidt T, Tjwa M, van Geyte K, Lievens D, Lutgens E, Vanhoutte D, Borgel D, Plaisance S, Hoylaerts M, Luttun A, Dewerchin M, Jonckx B, Carmeliet P (2010) Malignant cells fuel tumor growth by educating infiltrating leukocytes to produce the mitogen Gas6. Blood 115:2264-2273
-
(2010)
Blood
, vol.115
, pp. 2264-2273
-
-
Loges, S.1
Schmidt, T.2
Tjwa, M.3
Van Geyte, K.4
Lievens, D.5
Lutgens, E.6
Vanhoutte, D.7
Borgel, D.8
Plaisance, S.9
Hoylaerts, M.10
Luttun, A.11
Dewerchin, M.12
Jonckx, B.13
Carmeliet, P.14
-
58
-
-
26644437199
-
SHIP represses the generation of alternatively activated macrophages
-
Rauh MJ, Ho V, Pereira C, Sham A, Sly LM, Lam V, Huxham L, Minchinton AI, Mui A, Krystal G (2005) SHIP represses the generation of alternatively activated macrophages. Immunity 23:361-374
-
(2005)
Immunity
, vol.23
, pp. 361-374
-
-
Rauh, M.J.1
Ho, V.2
Pereira, C.3
Sham, A.4
Sly, L.M.5
Lam, V.6
Huxham, L.7
Minchinton, A.I.8
Mui, A.9
Krystal, G.10
-
59
-
-
77953752609
-
Notch signaling determines the M1 versus M2 polarization of macrophages in antitumor immune responses
-
Wang YC, He F, Feng F, Liu XW, Dong GY, Qin HY, Hu XB, Zheng MH, Liang L, Feng L, Liang YM, Han H (2011) Notch signaling determines the M1 versus M2 polarization of macrophages in antitumor immune responses. Cancer Res 70:4840-4849
-
(2011)
Cancer Res
, vol.70
, pp. 4840-4849
-
-
Wang, Y.C.1
He, F.2
Feng, F.3
Liu, X.W.4
Dong, G.Y.5
Qin, H.Y.6
Hu, X.B.7
Zheng, M.H.8
Liang, L.9
Feng, L.10
Liang, Y.M.11
Han, H.12
-
60
-
-
70349275277
-
Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor kappaB
-
Porta C, Rimoldi M, Raes G, Brys L, Ghezzi P, Di Liberto D, Dieli F, Ghisletti S, Natoli G, De Baetselier P, Mantovani A, Sica A (2009) Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor kappaB. Proc Natl Acad Sci U S A 106:14978-14983
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 14978-14983
-
-
Porta, C.1
Rimoldi, M.2
Raes, G.3
Brys, L.4
Ghezzi, P.5
Di Liberto, D.6
Dieli, F.7
Ghisletti, S.8
Natoli, G.9
De Baetselier, P.10
Mantovani, A.11
Sica, A.12
-
61
-
-
33845420396
-
The role of cytokines in hepatocellular carcinoma
-
Budhu A, Wang XW (2006) The role of cytokines in hepatocellular carcinoma. J Leukoc Biol 80:1197-1213
-
(2006)
J Leukoc Biol
, vol.80
, pp. 1197-1213
-
-
Budhu, A.1
Wang, X.W.2
-
62
-
-
33749319703
-
Type, density, and location of immune cells within human colorectal tumors predict clinical outcome
-
Galon J, Costes A, Sanchez-Cabo F, Kirilovsky A, Mlecnik B, Lagorce-Pages C, Tosolini M, Camus M, Berger A, Wind P, Zinzindohoue F, Bruneval P, Cugnenc PH, Trajanoski Z, Fridman WH, Pages F (2006) Type, density, and location of immune cells within human colorectal tumors predict clinical outcome. Science 313:1960-1964
-
(2006)
Science
, vol.313
, pp. 1960-1964
-
-
Galon, J.1
Costes, A.2
Sanchez-Cabo, F.3
Kirilovsky, A.4
Mlecnik, B.5
Lagorce-Pages, C.6
Tosolini, M.7
Camus, M.8
Berger, A.9
Wind, P.10
Zinzindohoue, F.11
Bruneval, P.12
Cugnenc, P.H.13
Trajanoski, Z.14
Fridman, W.H.15
Pages, F.16
-
63
-
-
77954848626
-
Significance of M2-polarized tumor-associated macrophage in pancreatic cancer
-
Kurahara H, Shinchi H, Mataki Y, Maemura K, Noma H, Kubo F, Sakoda M, Ueno S, Natsugoe S, Takao S (2009) Significance of M2-polarized tumor-associated macrophage in pancreatic cancer. J Surg Res
-
(2009)
J Surg Res
-
-
Kurahara, H.1
Shinchi, H.2
Mataki, Y.3
Maemura, K.4
Noma, H.5
Kubo, F.6
Sakoda, M.7
Ueno, S.8
Natsugoe, S.9
Takao, S.10
-
64
-
-
77949345555
-
Tumor-associated macrophages and survival in classic Hodgkin's lymphoma
-
Steidl C, Lee T, Shah SP, Farinha P, Han G, Nayar T, Delaney A, Jones SJ, Iqbal J, Weisenburger DD, Bast MA, Rosenwald A, Muller-Hermelink HK, Rimsza LM, Campo E, Delabie J, Braziel RM, Cook JR, Tubbs RR, Jaffe ES, Lenz G, Connors JM, Staudt LM, Chan WC, Gascoyne RD (2010) Tumor-associated macrophages and survival in classic Hodgkin's lymphoma. N Engl J Med 362:875-885
-
(2010)
N Engl J Med
, vol.362
, pp. 875-885
-
-
Steidl, C.1
Lee, T.2
Shah, S.P.3
Farinha, P.4
Han, G.5
Nayar, T.6
Delaney, A.7
Jones, S.J.8
Iqbal, J.9
Weisenburger, D.D.10
Bast, M.A.11
Rosenwald, A.12
Muller-Hermelink, H.K.13
Rimsza, L.M.14
Campo, E.15
Delabie, J.16
Braziel, R.M.17
Cook, J.R.18
Tubbs, R.R.19
Jaffe, E.S.20
Lenz, G.21
Connors, J.M.22
Staudt, L.M.23
Chan, W.C.24
Gascoyne, R.D.25
more..
-
65
-
-
33645760428
-
Ovarian cancer cells polarize macrophages toward a tumor-associated phenotype
-
Hagemann T, Wilson J, Burke F, Kulbe H, Li NF, Pluddemann A, Charles K, Gordon S, Balkwill FR (2006) Ovarian cancer cells polarize macrophages toward a tumor-associated phenotype. J Immunol 176:5023-5032
-
(2006)
J Immunol
, vol.176
, pp. 5023-5032
-
-
Hagemann, T.1
Wilson, J.2
Burke, F.3
Kulbe, H.4
Li, N.F.5
Pluddemann, A.6
Charles, K.7
Gordon, S.8
Balkwill, F.R.9
-
66
-
-
77956212940
-
Tumor-conditioned macrophages secrete migration-stimulating factor: A new marker for M2-polarization, influencing tumor cell motility
-
Solinas G, Schiarea S, Liguori M, Fabbri M, Pesce S, Zammataro L, Pasqualini F, Nebuloni M, Chiabrando C, Mantovani A, Allavena P (2010) Tumor-conditioned macrophages secrete migration-stimulating factor: a new marker for M2-polarization, influencing tumor cell motility. J Immunol 185:642-652
-
(2010)
J Immunol
, vol.185
, pp. 642-652
-
-
Solinas, G.1
Schiarea, S.2
Liguori, M.3
Fabbri, M.4
Pesce, S.5
Zammataro, L.6
Pasqualini, F.7
Nebuloni, M.8
Chiabrando, C.9
Mantovani, A.10
Allavena, P.11
-
67
-
-
71749088821
-
CCL2 and interleukin-6 promote survival of human CD11b + peripheral blood mononuclear cells and induce M2-type macrophage polarization
-
Roca H, Varsos ZS, Sud S, Craig MJ, Ying C, Pienta KJ (2009) CCL2 and interleukin-6 promote survival of human CD11b + peripheral blood mononuclear cells and induce M2-type macrophage polarization. J Biol Chem 284:34342-34354
-
(2009)
J Biol Chem
, vol.284
, pp. 34342-34354
-
-
Roca, H.1
Varsos, Z.S.2
Sud, S.3
Craig, M.J.4
Ying, C.5
Pienta, K.J.6
-
68
-
-
33750813483
-
Transcriptional profiling of the human monocyte-tomacrophage differentiation and polarization: New molecules and patterns of gene expression
-
Martinez FO, Gordon S, Locati M, Mantovani A (2006) Transcriptional profiling of the human monocyte-tomacrophage differentiation and polarization: new molecules and patterns of gene expression. J Immunol 177:7303-7311
-
(2006)
J Immunol
, vol.177
, pp. 7303-7311
-
-
Martinez, F.O.1
Gordon, S.2
Locati, M.3
Mantovani, A.4
-
69
-
-
34548805636
-
Cross-talk between myeloid-derived suppressor cells and macrophages subverts tumor immunity toward a type 2 response
-
Sinha P, Clements VK, Bunt SK, Albelda SM, Ostrand- Rosenberg S (2007) Cross-talk between myeloid-derived suppressor cells and macrophages subverts tumor immunity toward a type 2 response. J Immunol 179:977-983
-
(2007)
J Immunol
, vol.179
, pp. 977-983
-
-
Sinha, P.1
Clements, V.K.2
Bunt, S.K.3
Albelda, S.M.4
Ostrand-Rosenberg, S.5
-
70
-
-
70949103794
-
Cancer associated fibroblasts promote tumor growth and metastasis by modulating the tumor immune microenvironment in a 4T1 murine breast cancer model
-
Liao D, Luo Y, Markowitz D, Xiang R, Reisfeld RA (2009) Cancer associated fibroblasts promote tumor growth and metastasis by modulating the tumor immune microenvironment in a 4T1 murine breast cancer model. PLoS ONE 4:e7965
-
(2009)
PLoS ONE
, vol.4
-
-
Liao, D.1
Luo, Y.2
Markowitz, D.3
Xiang, R.4
Reisfeld, R.A.5
-
71
-
-
76349096670
-
Cancerassociated fibroblasts are activated in incipient neoplasia to orchestrate tumor-promoting inflammation in an NF-kappaBdependent manner
-
Erez N, Truitt M, Olson P, Arron ST, Hanahan D (2010) Cancerassociated fibroblasts are activated in incipient neoplasia to orchestrate tumor-promoting inflammation in an NF-kappaBdependent manner. Cancer Cell 17:135-147
-
(2010)
Cancer Cell
, vol.17
, pp. 135-147
-
-
Erez, N.1
Truitt, M.2
Olson, P.3
Arron, S.T.4
Hanahan, D.5
-
72
-
-
77956111527
-
Convergent pathways of macrophage polarization: The role of B cells
-
Sica A, Porta C, Riboldi E, Locati M (2010) Convergent pathways of macrophage polarization: the role of B cells. Eur J Immunol 40:2131-2133
-
(2010)
Eur J Immunol
, vol.40
, pp. 2131-2133
-
-
Sica, A.1
Porta, C.2
Riboldi, E.3
Locati, M.4
-
73
-
-
67651160649
-
CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages
-
DeNardo DG, Barreto JB, Andreu P, Vasquez L, Tawfik D, Kolhatkar N, Coussens LM (2009) CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages. Cancer Cell 16:91-102
-
(2009)
Cancer Cell
, vol.16
, pp. 91-102
-
-
DeNardo, D.G.1
Barreto, J.B.2
Andreu, P.3
Vasquez, L.4
Tawfik, D.5
Kolhatkar, N.6
Coussens, L.M.7
-
74
-
-
19344365408
-
De novo carcinogenesis promoted by chronic inflammation is B lymphocyte dependent
-
de Visser KE, Korets LV, Coussens LM (2005) De novo carcinogenesis promoted by chronic inflammation is B lymphocyte dependent. Cancer Cell 7:411-423
-
(2005)
Cancer Cell
, vol.7
, pp. 411-423
-
-
De Visser, K.E.1
Korets, L.V.2
Coussens, L.M.3
-
75
-
-
76349088502
-
FcRgamma activation regulates inflammation-associated squamous carcinogenesis
-
Andreu P, Johansson M, Affara NI, Pucci F, Tan T, Junankar S, Korets L, Lam J, Tawfik D, DeNardo DG, Naldini L, de Visser KE, De Palma M, Coussens LM (2010) FcRgamma activation regulates inflammation-associated squamous carcinogenesis. Cancer Cell 17:121-134
-
(2010)
Cancer Cell
, vol.17
, pp. 121-134
-
-
Andreu, P.1
Johansson, M.2
Affara, N.I.3
Pucci, F.4
Tan, T.5
Junankar, S.6
Korets, L.7
Lam, J.8
Tawfik, D.9
DeNardo, D.G.10
Naldini, L.11
De Visser, K.E.12
De Palma, M.13
Coussens, L.M.14
-
76
-
-
77956114905
-
Macrophage polarization to a unique phenotype driven by B cells
-
Wong SC, Puaux AL, Chittezhath M, Shalova I, Kajiji TS, Wang X, Abastado JP, Lam KP, Biswas SK (2010) Macrophage polarization to a unique phenotype driven by B cells. Eur J Immunol 40:2296-2307
-
(2010)
Eur J Immunol
, vol.40
, pp. 2296-2307
-
-
Wong, S.C.1
Puaux, A.L.2
Chittezhath, M.3
Shalova, I.4
Kajiji, T.S.5
Wang, X.6
Abastado, J.P.7
Lam, K.P.8
Biswas, S.K.9
-
77
-
-
68949150545
-
Tie2-expressing monocytes (TEMs): Novel targets and vehicles of anticancer therapy?
-
De Palma M, Naldini L (2009) Tie2-expressing monocytes (TEMs): novel targets and vehicles of anticancer therapy? Biochim Biophys Acta 1796:5-10
-
(2009)
Biochim Biophys Acta
, vol.1796
, pp. 5-10
-
-
De Palma, M.1
Naldini, L.2
-
78
-
-
79955006478
-
Angiopoietin 2 stimulates TIE2-expressing monocytes to suppress T cell activation and to promote regulatory T cell expansion
-
Coffelt SB, Chen YY, Muthana M, Welford AF, Tal AO, Scholz A, Plate KH, Reiss Y, Murdoch C, De Palma M, Lewis CE (2011) Angiopoietin 2 stimulates TIE2-expressing monocytes to suppress T cell activation and to promote regulatory T cell expansion. J Immunol 186:4183-4190
-
(2011)
J Immunol
, vol.186
, pp. 4183-4190
-
-
Coffelt, S.B.1
Chen, Y.Y.2
Muthana, M.3
Welford, A.F.4
Tal, A.O.5
Scholz, A.6
Plate, K.H.7
Reiss, Y.8
Murdoch, C.9
De Palma, M.10
Lewis, C.E.11
-
79
-
-
0038644403
-
Targeting exogenous genes to tumor angiogenesis by transplantation of genetically modified hematopoietic stem cells
-
De Palma M, Venneri MA, Roca C, Naldini L (2003) Targeting exogenous genes to tumor angiogenesis by transplantation of genetically modified hematopoietic stem cells. Nat Med 9:789-795
-
(2003)
Nat Med
, vol.9
, pp. 789-795
-
-
De Palma, M.1
Venneri, M.A.2
Roca, C.3
Naldini, L.4
-
80
-
-
67651111095
-
A distinguishing gene signature shared by tumor-infiltrating Tie2-expressing monocytes, blood "resident" monocytes, and embryonic macrophages suggests common functions and developmental relationships
-
Pucci F, Venneri MA, Biziato D, Nonis A, Moi D, Sica A, Di Serio C, Naldini L, De Palma M (2009) A distinguishing gene signature shared by tumor-infiltrating Tie2-expressing monocytes, blood "resident" monocytes, and embryonic macrophages suggests common functions and developmental relationships. Blood 114:901-914
-
(2009)
Blood
, vol.114
, pp. 901-914
-
-
Pucci, F.1
Venneri, M.A.2
Biziato, D.3
Nonis, A.4
Moi, D.5
Sica, A.6
Di Serio, C.7
Naldini, L.8
De Palma, M.9
-
81
-
-
77954369555
-
Angiopoietin-2 regulates gene expression in TIE2-expressing monocytes and augments their inherent proangiogenic functions
-
Coffelt SB, Tal AO, Scholz A, De Palma M, Patel S, Urbich C, Biswas SK, Murdoch C, Plate KH, Reiss Y, Lewis CE (2010) Angiopoietin-2 regulates gene expression in TIE2-expressing monocytes and augments their inherent proangiogenic functions. Cancer Res 70:5270-5280
-
(2010)
Cancer Res
, vol.70
, pp. 5270-5280
-
-
Coffelt, S.B.1
Tal, A.O.2
Scholz, A.3
De Palma, M.4
Patel, S.5
Urbich, C.6
Biswas, S.K.7
Murdoch, C.8
Plate, K.H.9
Reiss, Y.10
Lewis, C.E.11
-
82
-
-
61349100687
-
Myeloid-derived suppressor cells as regulators of the immune system
-
Gabrilovich DI, Nagaraj S (2009) Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol 9:162-174
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 162-174
-
-
Gabrilovich, D.I.1
Nagaraj, S.2
-
83
-
-
65249138393
-
Myeloid-derived suppressor cells: Linking inflammation and cancer
-
Ostrand-Rosenberg S, Sinha P (2009) Myeloid-derived suppressor cells: linking inflammation and cancer. J Immunol 182:4499-4506
-
(2009)
J Immunol
, vol.182
, pp. 4499-4506
-
-
Ostrand-Rosenberg, S.1
Sinha, P.2
-
84
-
-
54049134747
-
Subsets of myeloid-derived suppressor cells in tumor-bearing mice
-
Youn JI, Nagaraj S, Collazo M, Gabrilovich DI (2008) Subsets of myeloid-derived suppressor cells in tumor-bearing mice. J Immunol 181:5791-5802
-
(2008)
J Immunol
, vol.181
, pp. 5791-5802
-
-
Youn, J.I.1
Nagaraj, S.2
Collazo, M.3
Gabrilovich, D.I.4
-
85
-
-
43249130187
-
Identification of discrete tumor-induced myeloidderived suppressor cell subpopulations with distinct T cellsuppressive activity
-
Movahedi K, Guilliams M, Van den Bossche J, Van den Bergh R, Gysemans C, Beschin A, De Baetselier P, Van Ginderachter JA (2008) Identification of discrete tumor-induced myeloidderived suppressor cell subpopulations with distinct T cellsuppressive activity. Blood 111:4233-4244
-
(2008)
Blood
, vol.111
, pp. 4233-4244
-
-
Movahedi, K.1
Guilliams, M.2
Van Den Bossche, J.3
Van Den Bergh, R.4
Gysemans, C.5
Beschin, A.6
De Baetselier, P.7
Van Ginderachter, J.A.8
-
86
-
-
20944434107
-
Boosting antitumor responses of T lymphocytes infiltrating human prostate cancers
-
Bronte V, Kasic T, Gri G, Gallana K, Borsellino G, Marigo I, Battistini L, Iafrate M, Prayer-Galetti T, Pagano F, Viola A (2005) Boosting antitumor responses of T lymphocytes infiltrating human prostate cancers. J Exp Med 201:1257-1268
-
(2005)
J Exp Med
, vol.201
, pp. 1257-1268
-
-
Bronte, V.1
Kasic, T.2
Gri, G.3
Gallana, K.4
Borsellino, G.5
Marigo, I.6
Battistini, L.7
Iafrate, M.8
Prayer-Galetti, T.9
Pagano, F.10
Viola, A.11
-
87
-
-
34447118098
-
Altered recognition of antigen is a mechanism of CD8+ T cell tolerance in cancer
-
Nagaraj S, Gupta K, Pisarev V, Kinarsky L, Sherman S, Kang L, Herber DL, Schneck J, Gabrilovich DI (2007) Altered recognition of antigen is a mechanism of CD8+ T cell tolerance in cancer. Nat Med 13:828-835
-
(2007)
Nat Med
, vol.13
, pp. 828-835
-
-
Nagaraj, S.1
Gupta, K.2
Pisarev, V.3
Kinarsky, L.4
Sherman, S.5
Kang, L.6
Herber, D.L.7
Schneck, J.8
Gabrilovich, D.I.9
-
88
-
-
75149123468
-
Myeloid-derived suppressor cells inhibit T-cell activation by depleting cystine and cysteine
-
Srivastava MK, Sinha P, Clements VK, Rodriguez P, Ostrand-Rosenberg S (2010) Myeloid-derived suppressor cells inhibit T-cell activation by depleting cystine and cysteine. Cancer Res 70:68-77
-
(2010)
Cancer Res
, vol.70
, pp. 68-77
-
-
Srivastava, M.K.1
Sinha, P.2
Clements, V.K.3
Rodriguez, P.4
Ostrand-Rosenberg, S.5
-
89
-
-
33746115391
-
CD80 in immune suppression by mouse ovarian carcinoma-associated Gr-1 + CD11b + myeloid cells
-
Yang R, Cai Z, Zhang Y, Yutzy WHT, Roby KF, Roden RB (2006) CD80 in immune suppression by mouse ovarian carcinoma-associated Gr-1 + CD11b + myeloid cells. Cancer Res 66:6807-6815
-
(2006)
Cancer Res
, vol.66
, pp. 6807-6815
-
-
Yang, R.1
Cai, Z.2
Zhang, Y.3
Yutzy, W.H.T.4
Roby, K.F.5
Roden, R.B.6
-
90
-
-
31544446571
-
Gr-1 + CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host
-
Huang B, Pan PY, Li Q, Sato AI, Levy DE, Bromberg J, Divino CM, Chen SH (2006) Gr-1 + CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host. Cancer Res 66:1123-1131
-
(2006)
Cancer Res
, vol.66
, pp. 1123-1131
-
-
Huang, B.1
Pan, P.Y.2
Li, Q.3
Sato, A.I.4
Levy, D.E.5
Bromberg, J.6
Divino, C.M.7
Chen, S.H.8
-
91
-
-
10744220561
-
Transforming growth factorbeta production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocyte-mediated tumor immunosurveillance: Abrogation prevents tumor recurrence
-
Terabe M, Matsui S, Park JM, Mamura M, Noben-Trauth N, Donaldson DD, Chen W, Wahl SM, Ledbetter S, Pratt B, Letterio JJ, Paul WE, Berzofsky JA (2003) Transforming growth factorbeta production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocyte-mediated tumor immunosurveillance: abrogation prevents tumor recurrence. J Exp Med 198:1741-1752
-
(2003)
J Exp Med
, vol.198
, pp. 1741-1752
-
-
Terabe, M.1
Matsui, S.2
Park, J.M.3
Mamura, M.4
Noben-Trauth, N.5
Donaldson, D.D.6
Chen, W.7
Wahl, S.M.8
Ledbetter, S.9
Pratt, B.10
Letterio, J.J.11
Paul, W.E.12
Berzofsky, J.A.13
-
92
-
-
78649586268
-
The biology of myeloidderived suppressor cells: The blessing and the curse of morphological and functional heterogeneity
-
Youn JI, Gabrilovich DI (2010) The biology of myeloidderived suppressor cells: the blessing and the curse of morphological and functional heterogeneity. Eur J Immunol 40:2969-2975
-
(2010)
Eur J Immunol
, vol.40
, pp. 2969-2975
-
-
Youn, J.I.1
Gabrilovich, D.I.2
-
93
-
-
77957991455
-
Myeloid-derived suppressor cells in human cancer
-
Nagaraj S, Gabrilovich DI (2010) Myeloid-derived suppressor cells in human cancer. Cancer J 16:348-353
-
(2010)
Cancer J
, vol.16
, pp. 348-353
-
-
Nagaraj, S.1
Gabrilovich, D.I.2
-
94
-
-
0035164478
-
Increased production of immature myeloid cells in cancer patients: A mechanism of immunosuppression in cancer
-
Almand B, Clark JI, Nikitina E, van Beynen J, English NR, Knight SC, Carbone DP, Gabrilovich DI (2001) Increased production of immature myeloid cells in cancer patients: a mechanism of immunosuppression in cancer. J Immunol 166:678-689
-
(2001)
J Immunol
, vol.166
, pp. 678-689
-
-
Almand, B.1
Clark, J.I.2
Nikitina, E.3
Van Beynen, J.4
English, N.R.5
Knight, S.C.6
Carbone, D.P.7
Gabrilovich, D.I.8
-
95
-
-
60549088732
-
Arginase I-producing myeloidderived suppressor cells in renal cell carcinoma are a subpopulation of activated granulocytes
-
Rodriguez PC, Ernstoff MS, Hernandez C, Atkins M, Zabaleta J, Sierra R, Ochoa AC (2009) Arginase I-producing myeloidderived suppressor cells in renal cell carcinoma are a subpopulation of activated granulocytes. Cancer Res 69:1553-1560
-
(2009)
Cancer Res
, vol.69
, pp. 1553-1560
-
-
Rodriguez, P.C.1
Ernstoff, M.S.2
Hernandez, C.3
Atkins, M.4
Zabaleta, J.5
Sierra, R.6
Ochoa, A.C.7
-
96
-
-
20244367914
-
Arginase-producing myeloid suppressor cells in renal cell carcinoma patients: A mechanism of tumor evasion
-
Zea AH, Rodriguez PC, Atkins MB, Hernandez C, Signoretti S, Zabaleta J, McDermott D, Quiceno D, Youmans A, O'Neill A, Mier J, Ochoa AC (2005) Arginase-producing myeloid suppressor cells in renal cell carcinoma patients: a mechanism of tumor evasion. Cancer Res 65:3044-3048
-
(2005)
Cancer Res
, vol.65
, pp. 3044-3048
-
-
Zea, A.H.1
Rodriguez, P.C.2
Atkins, M.B.3
Hernandez, C.4
Signoretti, S.5
Zabaleta, J.6
McDermott, D.7
Quiceno, D.8
Youmans, A.9
O'Neill, A.10
Mier, J.11
Ochoa, A.C.12
-
97
-
-
76149145359
-
Immunosuppressive CD14 + HLA-DRlow/- monocytes in prostate cancer
-
Vuk-Pavlovic S, Bulur PA, Lin Y, Qin R, Szumlanski CL, Zhao X, Dietz AB (2010) Immunosuppressive CD14 + HLA-DRlow/- monocytes in prostate cancer. Prostate 70:443-455
-
(2010)
Prostate
, vol.70
, pp. 443-455
-
-
Vuk-Pavlovic, S.1
Bulur, P.A.2
Lin, Y.3
Qin, R.4
Szumlanski, C.L.5
Zhao, X.6
Dietz, A.B.7
-
98
-
-
71449127523
-
Population alterations of L-arginase- and inducible nitric oxide synthase-expressed CD11b+/CD14/CD15+/ CD33+ myeloid-derived suppressor cells and CD8+ T lymphocytes in patients with advanced-stage non-small cell lung cancer
-
Liu CY, Wang YM, Wang CL, Feng PH, Ko HW, Liu YH, Wu YC, Chu Y, Chung FT, Kuo CH, Lee KY, Lin SM, Lin HC, Wang CH, Yu CT, Kuo HP (2009) Population alterations of L-arginase- and inducible nitric oxide synthase-expressed CD11b+/CD14/CD15+/ CD33+ myeloid-derived suppressor cells and CD8+ T lymphocytes in patients with advanced-stage non-small cell lung cancer. J Cancer Res Clin Oncol 136:35-45
-
(2009)
J Cancer Res Clin Oncol
, vol.136
, pp. 35-45
-
-
Liu, C.Y.1
Wang, Y.M.2
Wang, C.L.3
Feng, P.H.4
Ko, H.W.5
Liu, Y.H.6
Wu, Y.C.7
Chu, Y.8
Chung, F.T.9
Kuo, C.H.10
Lee, K.Y.11
Lin, S.M.12
Lin, H.C.13
Wang, C.H.14
Yu, C.T.15
Kuo, H.P.16
-
99
-
-
34447258415
-
Identification of a new subset of myeloid suppressor cells in peripheral blood of melanoma patients with modulation by a granulocytemacrophage colony-stimulation factor-based antitumor vaccine
-
Filipazzi P, Valenti R, Huber V, Pilla L, Canese P, Iero M, Castelli C, Mariani L, Parmiani G, Rivoltini L (2007) Identification of a new subset of myeloid suppressor cells in peripheral blood of melanoma patients with modulation by a granulocytemacrophage colony-stimulation factor-based antitumor vaccine. J Clin Oncol 25:2546-2553
-
(2007)
J Clin Oncol
, vol.25
, pp. 2546-2553
-
-
Filipazzi, P.1
Valenti, R.2
Huber, V.3
Pilla, L.4
Canese, P.5
Iero, M.6
Castelli, C.7
Mariani, L.8
Parmiani, G.9
Rivoltini, L.10
-
100
-
-
77953141534
-
Immature immunosuppressive CD14 + HLA-DR-/low cells in melanoma patients are Stat3hi and overexpress CD80, CD83, and DC-sign
-
Poschke I, Mougiakakos D, Hansson J, Masucci GV, Kiessling R (2010) Immature immunosuppressive CD14 + HLA-DR-/low cells in melanoma patients are Stat3hi and overexpress CD80, CD83, and DC-sign. Cancer Res 70:4335-4345
-
(2010)
Cancer Res
, vol.70
, pp. 4335-4345
-
-
Poschke, I.1
Mougiakakos, D.2
Hansson, J.3
Masucci, G.V.4
Kiessling, R.5
-
101
-
-
46049098560
-
A new population of myeloid-derived suppressor cells in hepatocellular carcinoma patients induces CD4(+)CD25(+)Foxp3(+) T cells
-
Hoechst B, Ormandy LA, Ballmaier M, Lehner F, Kruger C, Manns MP, Greten TF, Korangy F (2008) A new population of myeloid-derived suppressor cells in hepatocellular carcinoma patients induces CD4(+)CD25(+)Foxp3(+) T cells. Gastroenterology 135:234-243
-
(2008)
Gastroenterology
, vol.135
, pp. 234-243
-
-
Hoechst, B.1
Ormandy, L.A.2
Ballmaier, M.3
Lehner, F.4
Kruger, C.5
Manns, M.P.6
Greten, T.F.7
Korangy, F.8
-
102
-
-
77953914366
-
Tumorinduced tolerance and immune suppression depend on the C/ EBPbeta transcription factor
-
Marigo I, Bosio E, Solito S, Mesa C, Fernandez A, Dolcetti L, Ugel S, Sonda N, Bicciato S, Falisi E, Calabrese F, Basso G, Zanovello P, Cozzi E, Mandruzzato S, Bronte V (2010) Tumorinduced tolerance and immune suppression depend on the C/ EBPbeta transcription factor. Immunity 32:790-802
-
(2010)
Immunity
, vol.32
, pp. 790-802
-
-
Marigo, I.1
Bosio, E.2
Solito, S.3
Mesa, C.4
Fernandez, A.5
Dolcetti, L.6
Ugel, S.7
Sonda, N.8
Bicciato, S.9
Falisi, E.10
Calabrese, F.11
Basso, G.12
Zanovello, P.13
Cozzi, E.14
Mandruzzato, S.15
Bronte, V.16
-
103
-
-
78650756969
-
Molecular mechanisms regulating myeloid-derived suppressor cell differentiation and function
-
Condamine T, Gabrilovich DI (2011) Molecular mechanisms regulating myeloid-derived suppressor cell differentiation and function. Trends Immunol 32:19-25
-
(2011)
Trends Immunol
, vol.32
, pp. 19-25
-
-
Condamine, T.1
Gabrilovich, D.I.2
-
104
-
-
67149115417
-
Inflammation enhances myeloid-derived suppressor cell cross-talk by signaling through Toll-like receptor 4
-
Bunt SK, Clements VK, Hanson EM, Sinha P, Ostrand- Rosenberg S (2009) Inflammation enhances myeloid-derived suppressor cell cross-talk by signaling through Toll-like receptor 4. J Leukoc Biol 85:996-1004
-
(2009)
J Leukoc Biol
, vol.85
, pp. 996-1004
-
-
Bunt, S.K.1
Clements, V.K.2
Hanson, E.M.3
Sinha, P.4
Ostrand-Rosenberg, S.5
-
105
-
-
17044366637
-
STAT1 signaling regulates tumor-associated macrophage-mediated T cell deletion
-
Kusmartsev S, Gabrilovich DI (2005) STAT1 signaling regulates tumor-associated macrophage-mediated T cell deletion. J Immunol 174:4880-4891
-
(2005)
J Immunol
, vol.174
, pp. 4880-4891
-
-
Kusmartsev, S.1
Gabrilovich, D.I.2
-
106
-
-
78149330949
-
HIF-1alpha regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment
-
Corzo CA, Condamine T, Lu L, Cotter MJ, Youn JI, Cheng P, Cho HI, Celis E, Quiceno DG, Padhya T, McCaffrey TV, McCaffrey JC, Gabrilovich DI (2010) HIF-1alpha regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment. J Exp Med 207:2439-2453
-
(2010)
J Exp Med
, vol.207
, pp. 2439-2453
-
-
Corzo, C.A.1
Condamine, T.2
Lu, L.3
Cotter, M.J.4
Youn, J.I.5
Cheng, P.6
Cho, H.I.7
Celis, E.8
Quiceno, D.G.9
Padhya, T.10
McCaffrey, T.V.11
McCaffrey, J.C.12
Gabrilovich, D.I.13
-
107
-
-
79952772423
-
Paired immunoglobin-like receptor-B regulates the suppressive function and fate of myeloid-derived suppressor cells
-
Ma G, Pan PY, Eisenstein S, Divino CM, Lowell CA, Takai T, Chen SH (2011) Paired immunoglobin-like receptor-B regulates the suppressive function and fate of myeloid-derived suppressor cells. Immunity 34:385-395
-
(2011)
Immunity
, vol.34
, pp. 385-395
-
-
Ma, G.1
Pan, P.Y.2
Eisenstein, S.3
Divino, C.M.4
Lowell, C.A.5
Takai, T.6
Chen, S.H.7
-
108
-
-
5444225991
-
Expansion of myeloid immune suppressor Gr + CD11b + cells in tumorbearing host directly promotes tumor angiogenesis
-
Yang L, DeBusk LM, Fukuda K, Fingleton B, Green-Jarvis B, Shyr Y, Matrisian LM, Carbone DP, Lin PC (2004) Expansion of myeloid immune suppressor Gr + CD11b + cells in tumorbearing host directly promotes tumor angiogenesis. Cancer Cell 6:409-421
-
(2004)
Cancer Cell
, vol.6
, pp. 409-421
-
-
Yang, L.1
DeBusk, L.M.2
Fukuda, K.3
Fingleton, B.4
Green-Jarvis, B.5
Shyr, Y.6
Matrisian, L.M.7
Carbone, D.P.8
Lin, P.C.9
-
109
-
-
34547820876
-
Tumor refractoriness to anti- VEGF treatment is mediated by CD11b + Gr1+ myeloid cells
-
Shojaei F, Wu X, Malik AK, Zhong C, Baldwin ME, Schanz S, Fuh G, Gerber HP, Ferrara N (2007) Tumor refractoriness to anti- VEGF treatment is mediated by CD11b + Gr1+ myeloid cells. Nat Biotechnol 25:911-920
-
(2007)
Nat Biotechnol
, vol.25
, pp. 911-920
-
-
Shojaei, F.1
Wu, X.2
Malik, A.K.3
Zhong, C.4
Baldwin, M.E.5
Schanz, S.6
Fuh, G.7
Gerber, H.P.8
Ferrara, N.9
-
110
-
-
36849013036
-
Bv8 regulates myeloidcell-dependent tumour angiogenesis
-
Shojaei F, Wu X, Zhong C, Yu L, Liang XH, Yao J, Blanchard D, Bais C, Peale FV, van Bruggen N, Ho C, Ross J, Tan M, Carano RA, Meng YG, Ferrara N (2007) Bv8 regulates myeloidcell- dependent tumour angiogenesis. Nature 450:825-831
-
(2007)
Nature
, vol.450
, pp. 825-831
-
-
Shojaei, F.1
Wu, X.2
Zhong, C.3
Yu, L.4
Liang, X.H.5
Yao, J.6
Blanchard, D.7
Bais, C.8
Peale, F.V.9
Van Bruggen, N.10
Ho, C.11
Ross, J.12
Tan, M.13
Carano, R.A.14
Meng, Y.G.15
Ferrara, N.16
-
112
-
-
70449475343
-
Never underestimate the power of a neutrophil
-
Cassatella MA, Locati M, Mantovani A (2009) Never underestimate the power of a neutrophil. Immunity 31:698-700
-
(2009)
Immunity
, vol.31
, pp. 698-700
-
-
Cassatella, M.A.1
Locati, M.2
Mantovani, A.3
-
113
-
-
70449502228
-
Coactivation of Syk kinase and MyD88 adaptor protein pathways by bacteria promotes regulatory properties of neutrophils
-
Zhang X, Majlessi L, Deriaud E, Leclerc C, Lo-Man R (2009) Coactivation of Syk kinase and MyD88 adaptor protein pathways by bacteria promotes regulatory properties of neutrophils. Immunity 31:761-771
-
(2009)
Immunity
, vol.31
, pp. 761-771
-
-
Zhang, X.1
Majlessi, L.2
Deriaud, E.3
Leclerc, C.4
Lo-Man, R.5
-
114
-
-
77953565568
-
The paradox of tumor-associated neutrophils: Fueling tumor growth with cytotoxic substances
-
Houghton AM (2010) The paradox of tumor-associated neutrophils: fueling tumor growth with cytotoxic substances. Cell Cycle 9:1732-1737
-
(2010)
Cell Cycle
, vol.9
, pp. 1732-1737
-
-
Houghton, A.M.1
-
115
-
-
70350455089
-
Presence of intratumoral neutrophils is an independent prognostic factor in localized renal cell carcinoma
-
Jensen HK, Donskov F, Marcussen N, Nordsmark M, Lundbeck F, von der Maase H (2009) Presence of intratumoral neutrophils is an independent prognostic factor in localized renal cell carcinoma. J Clin Oncol 27:4709-4717
-
(2009)
J Clin Oncol
, vol.27
, pp. 4709-4717
-
-
Jensen, H.K.1
Donskov, F.2
Marcussen, N.3
Nordsmark, M.4
Lundbeck, F.5
Von Der Maase, H.6
-
116
-
-
22244461873
-
Alpha1-antitrypsin and neutrophil elastase imbalance and lung cancer risk
-
Yang P, Bamlet WR, Sun Z, Ebbert JO, Aubry MC, Krowka MJ, Taylor WR, Marks RS, Deschamps C, Swensen SJ, Wieben ED, Cunningham JM, Melton LJ, de Andrade M (2005) Alpha1- antitrypsin and neutrophil elastase imbalance and lung cancer risk. Chest 128:445-452
-
(2005)
Chest
, vol.128
, pp. 445-452
-
-
Yang, P.1
Bamlet, W.R.2
Sun, Z.3
Ebbert, J.O.4
Aubry, M.C.5
Krowka, M.J.6
Taylor, W.R.7
Marks, R.S.8
Deschamps, C.9
Swensen, S.J.10
Wieben, E.D.11
Cunningham, J.M.12
Melton, L.J.13
De Andrade, M.14
-
117
-
-
0345707663
-
Infiltration of neutrophils is required for acquisition of metastatic phenotype of benign murine fibrosarcoma cells: Implication of inflammationassociated carcinogenesis and tumor progression
-
Tazawa H, Okada F, Kobayashi T, Tada M, Mori Y, Une Y, Sendo F, Kobayashi M, Hosokawa M (2003) Infiltration of neutrophils is required for acquisition of metastatic phenotype of benign murine fibrosarcoma cells: implication of inflammationassociated carcinogenesis and tumor progression. Am J Pathol 163:2221-2232
-
(2003)
Am J Pathol
, vol.163
, pp. 2221-2232
-
-
Tazawa, H.1
Okada, F.2
Kobayashi, T.3
Tada, M.4
Mori, Y.5
Une, Y.6
Sendo, F.7
Kobayashi, M.8
Hosokawa, M.9
-
119
-
-
79953328298
-
Tumor-associated neutrophils: New targets for cancer therapy
-
Gregory AD, Houghton AM (2011) Tumor-associated neutrophils: new targets for cancer therapy. Cancer Res
-
(2011)
Cancer Res
-
-
Gregory, A.D.1
Houghton, A.M.2
-
120
-
-
69249242897
-
The yin-yang of tumor-associated neutrophils
-
Mantovani A (2009) The yin-yang of tumor-associated neutrophils. Cancer Cell 16:173-174
-
(2009)
Cancer Cell
, vol.16
, pp. 173-174
-
-
Mantovani, A.1
-
121
-
-
2342464085
-
The two NF-kappaB activation pathways and their role in innate and adaptive immunity
-
Bonizzi G, Karin M (2004) The two NF-kappaB activation pathways and their role in innate and adaptive immunity. Trends Immunol 25:280-288
-
(2004)
Trends Immunol
, vol.25
, pp. 280-288
-
-
Bonizzi, G.1
Karin, M.2
-
122
-
-
33745298519
-
Nuclear factor-kappaB in cancer development and progression
-
Karin M (2006) Nuclear factor-kappaB in cancer development and progression. Nature 441:431-436
-
(2006)
Nature
, vol.441
, pp. 431-436
-
-
Karin, M.1
-
123
-
-
34247566510
-
The family of five: TIR-domaincontaining adaptors in Toll-like receptor signalling
-
O'Neill LA, Bowie AG (2007) The family of five: TIR-domaincontaining adaptors in Toll-like receptor signalling. Nat Rev Immunol 7:353-364
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 353-364
-
-
O'Neill, L.A.1
Bowie, A.G.2
-
124
-
-
3142644996
-
Tumour-associated macrophages as a prototypic type II polarised phagocyte population: Role in tumour progression
-
Mantovani A, Allavena P, Sica A (2004) Tumour-associated macrophages as a prototypic type II polarised phagocyte population: role in tumour progression. Eur J Cancer 40:1660-1667
-
(2004)
Eur J Cancer
, vol.40
, pp. 1660-1667
-
-
Mantovani, A.1
Allavena, P.2
Sica, A.3
-
125
-
-
44849100198
-
NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha
-
Rius J, Guma M, Schachtrup C, Akassoglou K, Zinkernagel AS, Nizet V, Johnson RS, Haddad GG, Karin M (2008) NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha. Nature 453:807-811
-
(2008)
Nature
, vol.453
, pp. 807-811
-
-
Rius, J.1
Guma, M.2
Schachtrup, C.3
Akassoglou, K.4
Zinkernagel, A.S.5
Nizet, V.6
Johnson, R.S.7
Haddad, G.G.8
Karin, M.9
-
126
-
-
54549089856
-
Overexpression of interleukin-1beta induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice
-
Tu S, Bhagat G, Cui G, Takaishi S, Kurt-Jones EA, Rickman B, Betz KS, Penz-Oesterreicher M, Bjorkdahl O, Fox JG, Wang TC (2008) Overexpression of interleukin-1beta induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice. Cancer Cell 14:408-419
-
(2008)
Cancer Cell
, vol.14
, pp. 408-419
-
-
Tu, S.1
Bhagat, G.2
Cui, G.3
Takaishi, S.4
Kurt-Jones, E.A.5
Rickman, B.6
Betz, K.S.7
Penz-Oesterreicher, M.8
Bjorkdahl, O.9
Fox, J.G.10
Wang, T.C.11
-
127
-
-
79951756351
-
Upregulated myeloid-derived suppressor cell contributes to hepatocellular carcinoma development by impairing dendritic cell function
-
Hu CE, Gan J, Zhang RD, Cheng YR, Huang GJ (2011) Upregulated myeloid-derived suppressor cell contributes to hepatocellular carcinoma development by impairing dendritic cell function. Scand J Gastroenterol 46:156-164
-
(2011)
Scand J Gastroenterol
, vol.46
, pp. 156-164
-
-
Hu, C.E.1
Gan, J.2
Zhang, R.D.3
Cheng, Y.R.4
Huang, G.J.5
-
128
-
-
68249140395
-
Hypoxia-inducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia
-
Fang HY, Hughes R, Murdoch C, Coffelt SB, Biswas SK, Harris AL, Johnson RS, Imityaz HZ, Simon MC, Fredlund E, Greten FR, Rius J, Lewis CE (2009) Hypoxia-inducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia. Blood 114:844-859
-
(2009)
Blood
, vol.114
, pp. 844-859
-
-
Fang, H.Y.1
Hughes, R.2
Murdoch, C.3
Coffelt, S.B.4
Biswas, S.K.5
Harris, A.L.6
Johnson, R.S.7
Imityaz, H.Z.8
Simon, M.C.9
Fredlund, E.10
Greten, F.R.11
Rius, J.12
Lewis, C.E.13
-
129
-
-
70249099576
-
Interdependence of hypoxic and innate immune responses
-
Nizet V, Johnson RS (2009) Interdependence of hypoxic and innate immune responses. Nat Rev Immunol 9:609-617
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 609-617
-
-
Nizet, V.1
Johnson, R.S.2
-
130
-
-
24044461733
-
Macrophage responses to hypoxia: Implications for tumor progression and anti-cancer therapies
-
Lewis C, Murdoch C (2005) Macrophage responses to hypoxia: implications for tumor progression and anti-cancer therapies. Am J Pathol 167:627-635
-
(2005)
Am J Pathol
, vol.167
, pp. 627-635
-
-
Lewis, C.1
Murdoch, C.2
-
131
-
-
47749155653
-
Cancer related inflammation: The macrophage connection
-
Sica A, Allavena P, Mantovani A (2008) Cancer related inflammation: the macrophage connection. Cancer Lett 267:204-215
-
(2008)
Cancer Lett
, vol.267
, pp. 204-215
-
-
Sica, A.1
Allavena, P.2
Mantovani, A.3
-
132
-
-
4043184065
-
Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1
-
Ceradini DJ, Kulkarni AR, Callaghan MJ, Tepper OM, Bastidas N, Kleinman ME, Capla JM, Galiano RD, Levine JP, Gurtner GC (2004) Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1. Nat Med 10:858-864
-
(2004)
Nat Med
, vol.10
, pp. 858-864
-
-
Ceradini, D.J.1
Kulkarni, A.R.2
Callaghan, M.J.3
Tepper, O.M.4
Bastidas, N.5
Kleinman, M.E.6
Capla, J.M.7
Galiano, R.D.8
Levine, J.P.9
Gurtner, G.C.10
-
133
-
-
39849102836
-
HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion
-
Du R, Lu KV, Petritsch C, Liu P, Ganss R, Passegue E, Song H, Vandenberg S, Johnson RS, Werb Z, Bergers G (2008) HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion. Cancer Cell 13:206-220
-
(2008)
Cancer Cell
, vol.13
, pp. 206-220
-
-
Du, R.1
Lu, K.V.2
Petritsch, C.3
Liu, P.4
Ganss, R.5
Passegue, E.6
Song, H.7
Vandenberg, S.8
Johnson, R.S.9
Werb, Z.10
Bergers, G.11
-
134
-
-
66149092730
-
G-CSF-initiated myeloid cell mobilization and angiogenesis mediate tumor refractoriness to anti- VEGF therapy in mouse models
-
Shojaei F, Wu X, Qu X, Kowanetz M, Yu L, Tan M, Meng YG, Ferrara N (2009) G-CSF-initiated myeloid cell mobilization and angiogenesis mediate tumor refractoriness to anti- VEGF therapy in mouse models. Proc Natl Acad Sci U S A 106:6742-6747
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 6742-6747
-
-
Shojaei, F.1
Wu, X.2
Qu, X.3
Kowanetz, M.4
Yu, L.5
Tan, M.6
Meng, Y.G.7
Ferrara, N.8
-
135
-
-
19944432390
-
Hypoxia-induced neutrophil survival is mediated by HIF-1alpha-dependent NF-kappaB activity
-
Walmsley SR, Print C, Farahi N, Peyssonnaux C, Johnson RS, Cramer T, Sobolewski A, Condliffe AM, Cowburn AS, Johnson N, Chilvers ER (2005) Hypoxia-induced neutrophil survival is mediated by HIF-1alpha-dependent NF-kappaB activity. J Exp Med 201:105-115
-
(2005)
J Exp Med
, vol.201
, pp. 105-115
-
-
Walmsley, S.R.1
Print, C.2
Farahi, N.3
Peyssonnaux, C.4
Johnson, R.S.5
Cramer, T.6
Sobolewski, A.7
Condliffe, A.M.8
Cowburn, A.S.9
Johnson, N.10
Chilvers, E.R.11
-
136
-
-
13544250819
-
Macrophage arginase regulation by CCAAT/ enhancer-binding protein beta
-
Albina JE, Mahoney EJ, Daley JM, Wesche DE, Morris SM Jr, Reichner JS (2005) Macrophage arginase regulation by CCAAT/ enhancer-binding protein beta. Shock 23:168-172
-
(2005)
Shock
, vol.23
, pp. 168-172
-
-
Albina, J.E.1
Mahoney, E.J.2
Daley, J.M.3
Wesche, D.E.4
Morris Jr., S.M.5
Reichner, J.S.6
-
137
-
-
0028786601
-
A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter
-
Melillo G, Musso T, Sica A, Taylor LS, Cox GW, Varesio L (1995) A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter. J Exp Med 182:1683-1693
-
(1995)
J Exp Med
, vol.182
, pp. 1683-1693
-
-
Melillo, G.1
Musso, T.2
Sica, A.3
Taylor, L.S.4
Cox, G.W.5
Varesio, L.6
-
139
-
-
77649177217
-
Differential activation and antagonistic function of HIF- {alpha} isoforms in macrophages are essential for NO homeostasis
-
Takeda N, O'Dea EL, Doedens A, Kim JW, Weidemann A, Stockmann C, Asagiri M, Simon MC, Hoffmann A, Johnson RS (2010) Differential activation and antagonistic function of HIF- {alpha} isoforms in macrophages are essential for NO homeostasis. Genes Dev 24:491-501
-
(2010)
Genes Dev
, vol.24
, pp. 491-501
-
-
Takeda, N.1
O'Dea, E.L.2
Doedens, A.3
Kim, J.W.4
Weidemann, A.5
Stockmann, C.6
Asagiri, M.7
Simon, M.C.8
Hoffmann, A.9
Johnson, R.S.10
-
140
-
-
77955295091
-
Hypoxia-inducible factor 2alpha regulates macrophage function in mouse models of acute and tumor inflammation
-
Imtiyaz HZ, Williams EP, Hickey MM, Patel SA, Durham AC, Yuan LJ, Hammond R, Gimotty PA, Keith B, Simon MC (2010) Hypoxia-inducible factor 2alpha regulates macrophage function in mouse models of acute and tumor inflammation. J Clin Invest 120:2699-2714
-
(2010)
J Clin Invest
, vol.120
, pp. 2699-2714
-
-
Imtiyaz, H.Z.1
Williams, E.P.2
Hickey, M.M.3
Patel, S.A.4
Durham, A.C.5
Yuan, L.J.6
Hammond, R.7
Gimotty, P.A.8
Keith, B.9
Simon, M.C.10
-
141
-
-
77957350018
-
Macrophage expression of hypoxia-inducible factor-1 alpha suppresses T-cell function and promotes tumor progression
-
Doedens AL, Stockmann C, Rubinstein MP, Liao D, Zhang N, DeNardo DG, Coussens LM, Karin M, Goldrath AW, Johnson RS (2010) Macrophage expression of hypoxia-inducible factor-1 alpha suppresses T-cell function and promotes tumor progression. Cancer Res 70:7465-7475
-
(2010)
Cancer Res
, vol.70
, pp. 7465-7475
-
-
Doedens, A.L.1
Stockmann, C.2
Rubinstein, M.P.3
Liao, D.4
Zhang, N.5
DeNardo, D.G.6
Coussens, L.M.7
Karin, M.8
Goldrath, A.W.9
Johnson, R.S.10
-
142
-
-
35348904953
-
RSUME, a small RWD-containing protein, enhances SUMO conjugation and stabilizes HIF-1alpha during hypoxia
-
Carbia-Nagashima A, Gerez J, Perez-Castro C, Paez-Pereda M, Silberstein S, Stalla GK, Holsboer F, Arzt E (2007) RSUME, a small RWD-containing protein, enhances SUMO conjugation and stabilizes HIF-1alpha during hypoxia. Cell 131:309-323
-
(2007)
Cell
, vol.131
, pp. 309-323
-
-
Carbia-Nagashima, A.1
Gerez, J.2
Perez-Castro, C.3
Paez-Pereda, M.4
Silberstein, S.5
Stalla, G.K.6
Holsboer, F.7
Arzt, E.8
-
143
-
-
24744438663
-
Induction of interleukin-8 preserves the angiogenic response in HIF-1alpha-deficient colon cancer cells
-
Mizukami Y, Jo WS, Duerr EM, Gala M, Li J, Zhang X, Zimmer MA, Iliopoulos O, Zukerberg LR, Kohgo Y, Lynch MP, Rueda BR, Chung DC (2005) Induction of interleukin-8 preserves the angiogenic response in HIF-1alpha-deficient colon cancer cells. Nat Med 11:992-997
-
(2005)
Nat Med
, vol.11
, pp. 992-997
-
-
Mizukami, Y.1
Jo, W.S.2
Duerr, E.M.3
Gala, M.4
Li, J.5
Zhang, X.6
Zimmer, M.A.7
Iliopoulos, O.8
Zukerberg, L.R.9
Kohgo, Y.10
Lynch, M.P.11
Rueda, B.R.12
Chung, D.C.13
-
144
-
-
33845868493
-
S100 proteins expressed in phagocytes: A novel group of damage-associated molecular pattern molecules
-
Foell D, Wittkowski H, Vogl T, Roth J (2007) S100 proteins expressed in phagocytes: a novel group of damage-associated molecular pattern molecules. J Leukoc Biol 81:28-37
-
(2007)
J Leukoc Biol
, vol.81
, pp. 28-37
-
-
Foell, D.1
Wittkowski, H.2
Vogl, T.3
Roth, J.4
-
145
-
-
33749425534
-
Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells
-
Gallina G, Dolcetti L, Serafini P, De Santo C, Marigo I, Colombo MP, Basso G, Brombacher F, Borrello I, Zanovello P, Bicciato S, Bronte V (2006) Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells. J Clin Invest 116:2777-2790
-
(2006)
J Clin Invest
, vol.116
, pp. 2777-2790
-
-
Gallina, G.1
Dolcetti, L.2
Serafini, P.3
De Santo, C.4
Marigo, I.5
Colombo, M.P.6
Basso, G.7
Brombacher, F.8
Borrello, I.9
Zanovello, P.10
Bicciato, S.11
Bronte, V.12
-
146
-
-
48549085973
-
Myeloidderived suppressor cells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells
-
Serafini P, Mgebroff S, Noonan K, Borrello I (2008) Myeloidderived suppressor cells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells. Cancer Res 68:5439-5449
-
(2008)
Cancer Res
, vol.68
, pp. 5439-5449
-
-
Serafini, P.1
Mgebroff, S.2
Noonan, K.3
Borrello, I.4
-
147
-
-
28644445445
-
Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity
-
Kortylewski M, Kujawski M, Wang T, Wei S, Zhang S, Pilon- Thomas S, Niu G, Kay H, Mule J, Kerr WG, Jove R, Pardoll D, Yu H (2005) Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity. Nat Med 11:1314-1321
-
(2005)
Nat Med
, vol.11
, pp. 1314-1321
-
-
Kortylewski, M.1
Kujawski, M.2
Wang, T.3
Wei, S.4
Zhang, S.5
Pilon-Thomas, S.6
Niu, G.7
Kay, H.8
Mule, J.9
Kerr, W.G.10
Jove, R.11
Pardoll, D.12
Yu, H.13
-
148
-
-
11144357779
-
Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells
-
Wang T, Niu G, Kortylewski M, Burdelya L, Shain K, Zhang S, Bhattacharya R, Gabrilovich D, Heller R, Coppola D, Dalton W, Jove R, Pardoll D, Yu H (2004) Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells. Nat Med 10:48-54
-
(2004)
Nat Med
, vol.10
, pp. 48-54
-
-
Wang, T.1
Niu, G.2
Kortylewski, M.3
Burdelya, L.4
Shain, K.5
Zhang, S.6
Bhattacharya, R.7
Gabrilovich, D.8
Heller, R.9
Coppola, D.10
Dalton, W.11
Jove, R.12
Pardoll, D.13
Yu, H.14
-
149
-
-
70349971417
-
In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses
-
Kortylewski M, Swiderski P, Herrmann A, Wang L, Kowolik C, Kujawski M, Lee H, Scuto A, Liu Y, Yang C, Deng J, Soifer HS, Raubitschek A, Forman S, Rossi JJ, Pardoll DM, Jove R, Yu H (2009) In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses. Nat Biotechnol 27:925-932
-
(2009)
Nat Biotechnol
, vol.27
, pp. 925-932
-
-
Kortylewski, M.1
Swiderski, P.2
Herrmann, A.3
Wang, L.4
Kowolik, C.5
Kujawski, M.6
Lee, H.7
Scuto, A.8
Liu, Y.9
Yang, C.10
Deng, J.11
Soifer, H.S.12
Raubitschek, A.13
Forman, S.14
Rossi, J.J.15
Pardoll, D.M.16
Jove, R.17
Yu, H.18
-
150
-
-
69849107597
-
Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments
-
Kryczek I, Banerjee M, Cheng P, Vatan L, Szeliga W, Wei S, Huang E, Finlayson E, Simeone D, Welling TH, Chang A, Coukos G, Liu R, Zou W (2009) Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments. Blood 114:1141-1149
-
(2009)
Blood
, vol.114
, pp. 1141-1149
-
-
Kryczek, I.1
Banerjee, M.2
Cheng, P.3
Vatan, L.4
Szeliga, W.5
Wei, S.6
Huang, E.7
Finlayson, E.8
Simeone, D.9
Welling, T.H.10
Chang, A.11
Coukos, G.12
Liu, R.13
Zou, W.14
-
152
-
-
34948820602
-
Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy
-
Apetoh L, Ghiringhelli F, Tesniere A, Obeid M, Ortiz C, Criollo A, Mignot G, Maiuri MC, Ullrich E, Saulnier P, Yang H, Amigorena S, Ryffel B, Barrat FJ, Saftig P, Levi F, Lidereau R, Nogues C, Mira JP, Chompret A, Joulin V, Clavel-Chapelon F, Bourhis J, Andre F, Delaloge S, Tursz T, Kroemer G, Zitvogel L (2007) Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy. Nat Med 13:1050-1059
-
(2007)
Nat Med
, vol.13
, pp. 1050-1059
-
-
Apetoh, L.1
Ghiringhelli, F.2
Tesniere, A.3
Obeid, M.4
Ortiz, C.5
Criollo, A.6
Mignot, G.7
Maiuri, M.C.8
Ullrich, E.9
Saulnier, P.10
Yang, H.11
Amigorena, S.12
Ryffel, B.13
Barrat, F.J.14
Saftig, P.15
Levi, F.16
Lidereau, R.17
Nogues, C.18
Mira, J.P.19
Chompret, A.20
Joulin, V.21
Clavel-Chapelon, F.22
Bourhis, J.23
Andre, F.24
Delaloge, S.25
Tursz, T.26
Kroemer, G.27
Zitvogel, L.28
more..
-
153
-
-
70350569295
-
Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors
-
Ghiringhelli F, Apetoh L, Tesniere A, Aymeric L, Ma Y, Ortiz C, Vermaelen K, Panaretakis T, Mignot G, Ullrich E, Perfettini JL, Schlemmer F, Tasdemir E, Uhl M, Genin P, Civas A, Ryffel B, Kanellopoulos J, Tschopp J, Andre F, Lidereau R, McLaughlin NM, Haynes NM, Smyth MJ, Kroemer G, Zitvogel L (2009) Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors. Nat Med 15:1170-1178
-
(2009)
Nat Med
, vol.15
, pp. 1170-1178
-
-
Ghiringhelli, F.1
Apetoh, L.2
Tesniere, A.3
Aymeric, L.4
Ma, Y.5
Ortiz, C.6
Vermaelen7
-
154
-
-
38649088939
-
A Legumain-based minigene vaccine targets the tumor stroma and suppresses breast cancer growth and angiogenesis
-
Lewen S, Zhou H, Hu HD, Cheng T, Markowitz D, Reisfeld RA, Xiang R, Luo Y (2008) A Legumain-based minigene vaccine targets the tumor stroma and suppresses breast cancer growth and angiogenesis. Cancer Immunol Immunother 57:507-515
-
(2008)
Cancer Immunol Immunother
, vol.57
, pp. 507-515
-
-
Lewen, S.1
Zhou, H.2
Hu, H.D.3
Cheng, T.4
Markowitz, D.5
Reisfeld, R.A.6
Xiang, R.7
Luo, Y.8
-
155
-
-
78651461701
-
HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF
-
Rolny C, Mazzone M, Tugues S, Laoui D, Johansson I, Coulon C, Squadrito ML, Segura I, Li X, Knevels E, Costa S, Vinckier S, Dresselaer T, Akerud P, De Mol M, Salomaki H, Phillipson M, Wyns S, Larsson E, Buysschaert I, Botling J, Himmelreich U, Van Ginderachter JA, De Palma M, Dewerchin M, Claesson- Welsh L, Carmeliet P (2011) HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF. Cancer Cell 19:31-44
-
(2011)
Cancer Cell
, vol.19
, pp. 31-44
-
-
Rolny, C.1
Mazzone, M.2
Tugues, S.3
Laoui, D.4
Johansson, I.5
Coulon, C.6
Squadrito, M.L.7
Segura, I.8
Li, X.9
Knevels, E.10
Costa, S.11
Vinckier, S.12
Dresselaer, T.13
Akerud, P.14
De Mol, M.15
Salomaki, H.16
Phillipson, M.17
Wyns, S.18
Larsson, E.19
Buysschaert, I.20
Botling, J.21
Himmelreich, U.22
Van Ginderachter, J.A.23
De Palma, M.24
Dewerchin, M.25
Claesson-Welsh, L.26
Carmeliet, P.27
more..
-
156
-
-
34447556692
-
Targeting tumor-associated macrophages and inhibition of MCP-1 reduce angiogenesis and tumor growth in a human melanoma xenograft
-
Gazzaniga S, Bravo AI, Guglielmotti A, van Rooijen N, Maschi F, Vecchi A, Mantovani A, Mordoh J, Wainstok R (2007) Targeting tumor-associated macrophages and inhibition of MCP-1 reduce angiogenesis and tumor growth in a human melanoma xenograft. J Invest Dermatol 127:2031-2041
-
(2007)
J Invest Dermatol
, vol.127
, pp. 2031-2041
-
-
Gazzaniga, S.1
Bravo, A.I.2
Guglielmotti, A.3
Van Rooijen, N.4
Maschi, F.5
Vecchi, A.6
Mantovani, A.7
Mordoh, J.8
Wainstok, R.9
-
157
-
-
79952110492
-
Antitumor effects and anticancer applications of bisphosphonates
-
Morgan G, Lipton A (2010) Antitumor effects and anticancer applications of bisphosphonates. Semin Oncol 37(Suppl 2):S30-S40
-
(2010)
Semin Oncol
, vol.37
, Issue.SUPPL. 2
-
-
Morgan, G.1
Lipton, A.2
-
158
-
-
67449088117
-
Interferon-gamma reverses the immunosuppressive and protumoral properties and prevents the generation of human tumorassociated macrophages
-
Duluc D, Corvaisier M, Blanchard S, Catala L, Descamps P, Gamelin E, Ponsoda S, Delneste Y, Hebbar M, Jeannin P (2009) Interferon-gamma reverses the immunosuppressive and protumoral properties and prevents the generation of human tumorassociated macrophages. Int J Cancer 125:367-373
-
(2009)
Int J Cancer
, vol.125
, pp. 367-373
-
-
Duluc, D.1
Corvaisier, M.2
Blanchard, S.3
Catala, L.4
Descamps, P.5
Gamelin, E.6
Ponsoda, S.7
Delneste, Y.8
Hebbar, M.9
Jeannin, P.10
-
159
-
-
78650051896
-
Zoledronic acid repolarizes tumour-associated macrophages and inhibits mammary carcinogenesis by targeting the mevalonate pathway
-
Coscia M, Quaglino E, Iezzi M, Curcio C, Pantaleoni F, Riganti C, Holen I, Monkkonen H, Boccadoro M, Forni G, Musiani P, Bosia A, Cavallo F, Massaia M (2010) Zoledronic acid repolarizes tumour-associated macrophages and inhibits mammary carcinogenesis by targeting the mevalonate pathway. J Cell Mol Med 14:2803-2815
-
(2010)
J Cell Mol Med
, vol.14
, pp. 2803-2815
-
-
Coscia, M.1
Quaglino, E.2
Iezzi, M.3
Curcio, C.4
Pantaleoni, F.5
Riganti, C.6
Holen, I.7
Monkkonen, H.8
Boccadoro, M.9
Forni, G.10
Musiani, P.11
Bosia, A.12
Cavallo, F.13
Massaia, M.14
-
160
-
-
17144398046
-
Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection
-
Guiducci C, Vicari AP, Sangaletti S, Trinchieri G, Colombo MP (2005) Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection. Cancer Res 65:3437-3446
-
(2005)
Cancer Res
, vol.65
, pp. 3437-3446
-
-
Guiducci, C.1
Vicari, A.P.2
Sangaletti, S.3
Trinchieri, G.4
Colombo, M.P.5
-
161
-
-
0034544609
-
Cutting edge: STAT6-deficient mice have enhanced tumor immunity to primary and metastatic mammary carcinoma
-
Ostrand-Rosenberg S, Grusby MJ, Clements VK (2000) Cutting edge: STAT6-deficient mice have enhanced tumor immunity to primary and metastatic mammary carcinoma. J Immunol 165:6015-6019
-
(2000)
J Immunol
, vol.165
, pp. 6015-6019
-
-
Ostrand-Rosenberg, S.1
Grusby, M.J.2
Clements, V.K.3
-
162
-
-
52949148222
-
Tumor-targeted interferon-alpha delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis
-
De Palma M, Mazzieri R, Politi LS, Pucci F, Zonari E, Sitia G, Mazzoleni S, Moi D, Venneri MA, Indraccolo S, Falini A, Guidotti LG, Galli R, Naldini L (2008) Tumor-targeted interferon-alpha delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis. Cancer Cell 14:299-311
-
(2008)
Cancer Cell
, vol.14
, pp. 299-311
-
-
De Palma, M.1
Mazzieri, R.2
Politi, L.S.3
Pucci, F.4
Zonari, E.5
Sitia, G.6
Mazzoleni, S.7
Moi, D.8
Venneri, M.A.9
Indraccolo, S.10
Falini, A.11
Guidotti, L.G.12
Galli, R.13
Naldini, L.14
-
163
-
-
0035339932
-
Mechanism of immune dysfunction in cancer mediated by immature Gr-1+ myeloid cells
-
Gabrilovich DI, Velders MP, Sotomayor EM, Kast WM (2001) Mechanism of immune dysfunction in cancer mediated by immature Gr-1+ myeloid cells. J Immunol 166:5398-5406
-
(2001)
J Immunol
, vol.166
, pp. 5398-5406
-
-
Gabrilovich, D.I.1
Velders, M.P.2
Sotomayor, E.M.3
Kast, W.M.4
-
164
-
-
0042591427
-
All-trans-retinoic acid eliminates immature myeloid cells from tumor-bearing mice and improves the effect of vaccination
-
Kusmartsev S, Cheng F, Yu B, Nefedova Y, Sotomayor E, Lush R, Gabrilovich D (2003) All-trans-retinoic acid eliminates immature myeloid cells from tumor-bearing mice and improves the effect of vaccination. Cancer Res 63:4441-4449
-
(2003)
Cancer Res
, vol.63
, pp. 4441-4449
-
-
Kusmartsev, S.1
Cheng, F.2
Yu, B.3
Nefedova, Y.4
Sotomayor, E.5
Lush, R.6
Gabrilovich, D.7
-
165
-
-
33749461167
-
All-transretinoic acid improves differentiation of myeloid cells and immune response in cancer patients
-
Mirza N, Fishman M, Fricke I, Dunn M, Neuger AM, Frost TJ, Lush RM, Antonia S, Gabrilovich DI (2006) All-transretinoic acid improves differentiation of myeloid cells and immune response in cancer patients. Cancer Res 66:9299-9307
-
(2006)
Cancer Res
, vol.66
, pp. 9299-9307
-
-
Mirza, N.1
Fishman, M.2
Fricke, I.3
Dunn, M.4
Neuger, A.M.5
Frost, T.J.6
Lush, R.M.7
Antonia, S.8
Gabrilovich, D.I.9
-
166
-
-
34547630506
-
A combination of chemoimmunotherapies can efficiently break self-tolerance and induce antitumor immunity in a tolerogenic murine tumor model
-
Ko HJ, Kim YJ, Kim YS, Chang WS, Ko SY, Chang SY, Sakaguchi S, Kang CY (2007) A combination of chemoimmunotherapies can efficiently break self-tolerance and induce antitumor immunity in a tolerogenic murine tumor model. Cancer Res 67:7477-7486
-
(2007)
Cancer Res
, vol.67
, pp. 7477-7486
-
-
Ko, H.J.1
Kim, Y.J.2
Kim, Y.S.3
Chang, W.S.4
Ko, S.Y.5
Chang, S.Y.6
Sakaguchi, S.7
Kang, C.Y.8
-
167
-
-
25144466458
-
Gemcitabine selectively eliminates splenic Gr-1+/ CD11b + myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity
-
Suzuki E, Kapoor V, Jassar AS, Kaiser LR, Albelda SM (2005) Gemcitabine selectively eliminates splenic Gr-1+/ CD11b + myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity. Clin Cancer Res 11:6713-6721
-
(2005)
Clin Cancer Res
, vol.11
, pp. 6713-6721
-
-
Suzuki, E.1
Kapoor, V.2
Jassar, A.S.3
Kaiser, L.R.4
Albelda, S.M.5
-
168
-
-
77954551165
-
Why not treat human cancer with interleukin-1 blockade?
-
Dinarello CA (2010) Why not treat human cancer with interleukin-1 blockade? Cancer Metastasis Rev 29:317-329
-
(2010)
Cancer Metastasis Rev
, vol.29
, pp. 317-329
-
-
Dinarello, C.A.1
-
169
-
-
65549145501
-
Neutrophils: Key mediators of tumour angiogenesis
-
Tazzyman S, Lewis CE, Murdoch C (2009) Neutrophils: key mediators of tumour angiogenesis. Int J Exp Pathol 90:222-231
-
(2009)
Int J Exp Pathol
, vol.90
, pp. 222-231
-
-
Tazzyman, S.1
Lewis, C.E.2
Murdoch, C.3
-
170
-
-
20144388299
-
Anti-inflammatory properties of the novel antitumor agent yondelis (trabectedin): Inhibition of macrophage differentiation and cytokine production
-
Allavena P, Signorelli M, Chieppa M, Erba E, Bianchi G, Marchesi F, Olimpio CO, Bonardi C, Garbi A, Lissoni A, de Braud F, Jimeno J, D'Incalci M (2005) Anti-inflammatory properties of the novel antitumor agent yondelis (trabectedin): inhibition of macrophage differentiation and cytokine production. Cancer Res 65:2964-2971
-
(2005)
Cancer Res
, vol.65
, pp. 2964-2971
-
-
Allavena, P.1
Signorelli, M.2
Chieppa, M.3
Erba, E.4
Bianchi, G.5
Marchesi, F.6
Olimpio, C.O.7
Bonardi, C.8
Garbi, A.9
Lissoni, A.10
De Braud, F.11
Jimeno, J.12
D'Incalci, M.13
-
171
-
-
41649116240
-
Plasticity in tumor-promoting inflammation: Impairment of macrophage recruitment evokes a compensatory neutrophil response
-
Pahler JC, Tazzyman S, Erez N, Chen YY, Murdoch C, Nozawa H, Lewis CE, Hanahan D (2008) Plasticity in tumor-promoting inflammation: impairment of macrophage recruitment evokes a compensatory neutrophil response. Neoplasia 10:329-340
-
(2008)
Neoplasia
, vol.10
, pp. 329-340
-
-
Pahler, J.C.1
Tazzyman, S.2
Erez, N.3
Chen, Y.Y.4
Murdoch, C.5
Nozawa, H.6
Lewis, C.E.7
Hanahan, D.8
-
172
-
-
41149136843
-
Polarized immune responses differentially regulate cancer development
-
Johansson M, Denardo DG, Coussens LM (2008) Polarized immune responses differentially regulate cancer development. Immunol Rev 222:145-154
-
(2008)
Immunol Rev
, vol.222
, pp. 145-154
-
-
Johansson, M.1
Denardo, D.G.2
Coussens, L.M.3
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