-
2
-
-
34548414532
-
Targeting uPA/uPAR in prostate cancer
-
Li Y and Cozzi PJ (2007). Targeting uPA/uPAR in prostate cancer. Cancer Treat Rev 33, 521-527.
-
(2007)
Cancer Treat Rev
, vol.33
, pp. 521-527
-
-
Li, Y.1
Cozzi, P.J.2
-
3
-
-
0025527558
-
Plasminogen activators and cancer
-
Duffy MJ (1990). Plasminogen activators and cancer. Blood Coagul Fibrinolysis 1, 681-687.
-
(1990)
Blood Coagul Fibrinolysis
, vol.1
, pp. 681-687
-
-
Duffy, M.J.1
-
4
-
-
0023831898
-
Sensitive and specific enzyme-linked immunosorbent assay for urokinase-type plasminogen activator and its application to plasma from patients with breast cancer
-
Grondahl-Hansen J, Agerlin N, Munkholm-Larsen P, Bach F, Nielsen LS, Dombernowsky P, and Dano K (1988). Sensitive and specific enzyme-linked immunosorbent assay for urokinase-type plasminogen activator and its application to plasma from patients with breast cancer. J Lab Clin Med 111, 42-51.
-
(1988)
J Lab Clin Med
, vol.111
, pp. 42-51
-
-
Grondahl-Hansen, J.1
Agerlin, N.2
Munkholm-Larsen, P.3
Bach, F.4
Nielsen, L.S.5
Dombernowsky, P.6
Dano, K.7
-
5
-
-
0026603255
-
The content of urokinase-type plasminogen activator antigen as a prognostic factor in urinary bladder cancer
-
Hasui Y, Marutsuka K, Suzumiya J, Kitada S, Osada Y, and Sumiyoshi A (1992). The content of urokinase-type plasminogen activator antigen as a prognostic factor in urinary bladder cancer. Int J Cancer 50, 871-873.
-
(1992)
Int J Cancer
, vol.50
, pp. 871-873
-
-
Hasui, Y.1
Marutsuka, K.2
Suzumiya, J.3
Kitada, S.4
Osada, Y.5
Sumiyoshi, A.6
-
6
-
-
0023948225
-
The urokinase type of plasminogen activator in cancer of digestive tracts
-
Nishino N, Aoki K, Tokura Y, Sakaguchi S, Takada Y, and Takada A (1988). The urokinase type of plasminogen activator in cancer of digestive tracts. Thromb Res 50, 527-535.
-
(1988)
Thromb Res
, vol.50
, pp. 527-535
-
-
Nishino, N.1
Aoki, K.2
Tokura, Y.3
Sakaguchi, S.4
Takada, Y.5
Takada, A.6
-
7
-
-
0033119221
-
Elevation of serum levels of urokinase-type plasminogen activator and its receptor is associated with disease progression and prognosis in patients with prostate cancer
-
Miyake H, Hara I, Yamanaka K, Gohji K, Arakawa S, and Kamidono S (1999). Elevation of serum levels of urokinase-type plasminogen activator and its receptor is associated with disease progression and prognosis in patients with prostate cancer. Prostate 39, 123-129.
-
(1999)
Prostate
, vol.39
, pp. 123-129
-
-
Miyake, H.1
Hara, I.2
Yamanaka, K.3
Gohji, K.4
Arakawa, S.5
Kamidono, S.6
-
8
-
-
33846978442
-
Association of the circulating levels of the urokinase system of plasminogen activation with the presence of prostate cancer and invasion, progression, and metastasis
-
Shariat SF, Roehrborn CG, McConnell JD, Park S, Alam N, Wheeler TM, and Slawin KM (2007). Association of the circulating levels of the urokinase system of plasminogen activation with the presence of prostate cancer and invasion, progression, and metastasis. J Clin Oncol 25, 349-355.
-
(2007)
J Clin Oncol
, vol.25
, pp. 349-355
-
-
Shariat, S.F.1
Roehrborn, C.G.2
McConnell, J.D.3
Park, S.4
Alam, N.5
Wheeler, T.M.6
Slawin, K.M.7
-
9
-
-
33847004756
-
Measurements of proteases or protease system components in blood to enhance prediction of disease risk or outcome in possible cancer
-
Lilja H, Vickers A, and Scardino P (2007). Measurements of proteases or protease system components in blood to enhance prediction of disease risk or outcome in possible cancer. J Clin Oncol 25, 347-348.
-
(2007)
J Clin Oncol
, vol.25
, pp. 347-348
-
-
Lilja, H.1
Vickers, A.2
Scardino, P.3
-
10
-
-
0033087688
-
Elevation of urokinase-type plasminogen activator and its receptor densities as new predictors of disease progression and prognosis in men with prostate cancer
-
Miyake H, Hara I, Yamanaka K, Arakawa S, and Kamidono S (1999). Elevation of urokinase-type plasminogen activator and its receptor densities as new predictors of disease progression and prognosis in men with prostate cancer. Int J Oncol 14, 535-541.
-
(1999)
Int J Oncol
, vol.14
, pp. 535-541
-
-
Miyake, H.1
Hara, I.2
Yamanaka, K.3
Arakawa, S.4
Kamidono, S.5
-
11
-
-
0029980844
-
Urokinasetype plasminogen activator expression in human prostate carcinomas
-
Van Veldhuizen PJ, Sadasivan R, Cherian R, and Wyatt A (1996). Urokinasetype plasminogen activator expression in human prostate carcinomas. Am J Med Sci 312, 8-11.
-
(1996)
Am J Med Sci
, vol.312
, pp. 8-11
-
-
van Veldhuizen, P.J.1
Sadasivan, R.2
Cherian, R.3
Wyatt, A.4
-
12
-
-
0035042671
-
Expression of urokinase plasminogen activator and receptor in conjunction with the ets family and AP-1 complex transcription factors in high grade prostate cancers
-
Gavrilov D, Kenzior O, Evans M, Calaluce R, and Folk WR (2001). Expression of urokinase plasminogen activator and receptor in conjunction with the ets family and AP-1 complex transcription factors in high grade prostate cancers. Eur J Cancer 37, 1033-1040.
-
(2001)
Eur J Cancer
, vol.37
, pp. 1033-1040
-
-
Gavrilov, D.1
Kenzior, O.2
Evans, M.3
Calaluce, R.4
Folk, W.R.5
-
13
-
-
11844272703
-
Expression of urokinase plasminogen activator, its receptor and type-1 inhibitor in malignant and benign prostate tissue
-
Usher PA, Thomsen OF, Iversen P, Johnsen M, Brunner N, Hoyer-Hansen G, Andreasen P, Dano K, and Nielsen BS (2005). Expression of urokinase plasminogen activator, its receptor and type-1 inhibitor in malignant and benign prostate tissue. Int J Cancer 113, 870-880.
-
(2005)
Int J Cancer
, vol.113
, pp. 870-880
-
-
Usher, P.A.1
Thomsen, O.F.2
Iversen, P.3
Johnsen, M.4
Brunner, N.5
Hoyer-Hansen, G.6
Andreasen, P.7
Dano, K.8
Nielsen, B.S.9
-
14
-
-
33750073572
-
Evaluation of urokinase plasminogen activator and its receptor in different grades of human prostate cancer
-
Cozzi PJ, Wang J, Delprado W, Madigan MC, Fairy S, Russell PJ, and Li Y (2006). Evaluation of urokinase plasminogen activator and its receptor in different grades of human prostate cancer. Hum Pathol 37, 1442-1451.
-
(2006)
Hum Pathol
, vol.37
, pp. 1442-1451
-
-
Cozzi, P.J.1
Wang, J.2
Delprado, W.3
Madigan, M.C.4
Fairy, S.5
Russell, P.J.6
Li, Y.7
-
15
-
-
33847034860
-
Demethylation-linked activation of urokinase plasminogen activator is involved in progression of prostate cancer
-
Pulukuri SM, Estes N, Patel J, and Rao JS (2007). Demethylation-linked activation of urokinase plasminogen activator is involved in progression of prostate cancer. Cancer Res 67, 930-939.
-
(2007)
Cancer Res
, vol.67
, pp. 930-939
-
-
Pulukuri, S.M.1
Estes, N.2
Patel, J.3
Rao, J.S.4
-
16
-
-
27744435789
-
RNA interference-directed knockdown of urokinase plasminogen activator and urokinase plasminogen activator receptor inhibits prostate cancer cell invasion, survival, and tumorigenicity in vivo
-
Pulukuri SM, Gondi CS, Lakka SS, Jutla A, Estes N, Gujrati M, and Rao JS (2005). RNA interference-directed knockdown of urokinase plasminogen activator and urokinase plasminogen activator receptor inhibits prostate cancer cell invasion, survival, and tumorigenicity in vivo. J Biol Chem 280, 36529-36540.
-
(2005)
J Biol Chem
, vol.280
, pp. 36529-36540
-
-
Pulukuri, S.M.1
Gondi, C.S.2
Lakka, S.S.3
Jutla, A.4
Estes, N.5
Gujrati, M.6
Rao, J.S.7
-
17
-
-
43249124467
-
Prostate cancer cell-derived urokinase-type plasminogen activator contributes to intraosseous tumor growth and bone turnover
-
Dong Z, Saliganan AD, Meng H, Nabha SM, Sabbota AL, Sheng S, Bonfil RD, and Cher ML (2008). Prostate cancer cell-derived urokinase-type plasminogen activator contributes to intraosseous tumor growth and bone turnover. Neoplasia 10, 439-449.
-
(2008)
Neoplasia
, vol.10
, pp. 439-449
-
-
Dong, Z.1
Saliganan, A.D.2
Meng, H.3
Nabha, S.M.4
Sabbota, A.L.5
Sheng, S.6
Bonfil, R.D.7
Cher, M.L.8
-
18
-
-
0028331139
-
The urokinase receptor is required for human monocyte chemotaxis in vitro
-
Gyetko MR, Todd RF III, Wilkinson CC, and Sitrin RG (1994). The urokinase receptor is required for human monocyte chemotaxis in vitro. J Clin Invest 93, 1380-1387.
-
(1994)
J Clin Invest
, vol.93
, pp. 1380-1387
-
-
Gyetko, M.R.1
Todd III, R.F.2
Wilkinson, C.C.3
Sitrin, R.G.4
-
19
-
-
40449112315
-
Urokinase-type plasminogen activator plays essential roles in macrophage chemotaxis and skeletal muscle regeneration
-
Bryer SC, Fantuzzi G, Van Rooijen N, and Koh TJ (2008). Urokinase-type plasminogen activator plays essential roles in macrophage chemotaxis and skeletal muscle regeneration. J Immunol 180, 1179-1188.
-
(2008)
J Immunol
, vol.180
, pp. 1179-1188
-
-
Bryer, S.C.1
Fantuzzi, G.2
van Rooijen, N.3
Koh, T.J.4
-
20
-
-
33645991795
-
Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: Potential targets of anti-cancer therapy
-
Sica A, Schioppa T, Mantovani A, and Allavena P (2006). Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: potential targets of anti-cancer therapy. Eur J Cancer 42, 717-727.
-
(2006)
Eur J Cancer
, vol.42
, pp. 717-727
-
-
Sica, A.1
Schioppa, T.2
Mantovani, A.3
Allavena, P.4
-
21
-
-
0035901090
-
Inflammation and cancer: Back to Virchow?
-
Balkwill F and Mantovani A (2001). Inflammation and cancer: back to Virchow? Lancet 357, 539-545.
-
(2001)
Lancet
, vol.357
, pp. 539-545
-
-
Balkwill, F.1
Mantovani, A.2
-
22
-
-
0037180757
-
Inflammation and cancer
-
Coussens LM and Werb Z (2002). Inflammation and cancer. Nature 420, 860-867.
-
(2002)
Nature
, vol.420
, pp. 860-867
-
-
Coussens, L.M.1
Werb, Z.2
-
23
-
-
70350728931
-
Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation
-
Solinas G, Germano G, Mantovani A, and Allavena P (2009). Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation. J Leukoc Biol 86, 1065-1073.
-
(2009)
J Leukoc Biol
, vol.86
, pp. 1065-1073
-
-
Solinas, G.1
Germano, G.2
Mantovani, A.3
Allavena, P.4
-
24
-
-
0029893122
-
Preservation of complement-induced lung injury in mice with deficiency of NADPH oxidase
-
Kubo H, Morgenstern D, Quinian WM, Ward PA, Dinauer MC, and Doerschuk CM (1996). Preservation of complement-induced lung injury in mice with deficiency of NADPH oxidase. J Clin Invest 97, 2680-2684.
-
(1996)
J Clin Invest
, vol.97
, pp. 2680-2684
-
-
Kubo, H.1
Morgenstern, D.2
Quinian, W.M.3
Ward, P.A.4
Dinauer, M.C.5
Doerschuk, C.M.6
-
25
-
-
0028295979
-
Physiological consequences of loss of plasminogen activator gene function in mice
-
Carmeliet P, Schoonjans L, Kieckens L, Ream B, Degen J, Bronson R, De Vos R, van den Oord JJ, Collen D, and Mulligan RC (1994). Physiological consequences of loss of plasminogen activator gene function in mice. Nature 368, 419-424.
-
(1994)
Nature
, vol.368
, pp. 419-424
-
-
Carmeliet, P.1
Schoonjans, L.2
Kieckens, L.3
Ream, B.4
Degen, J.5
Bronson, R.6
de Vos, R.7
van den Oord, J.J.8
Collen, D.9
Mulligan, R.C.10
-
26
-
-
0030045209
-
Generation and characterization of urokinase receptor-deficient mice
-
Dewerchin M, Nuffelen AV, Wallays G, Bouche A, Moons L, Carmeliet P, Mulligan RC, and Collen D (1996). Generation and characterization of urokinase receptor-deficient mice. J Clin Invest 97, 870-878.
-
(1996)
J Clin Invest
, vol.97
, pp. 870-878
-
-
Dewerchin, M.1
Nuffelen, A.V.2
Wallays, G.3
Bouche, A.4
Moons, L.5
Carmeliet, P.6
Mulligan, R.C.7
Collen, D.8
-
27
-
-
0029935421
-
Urokinase is required for the pulmonary inflammatory response to Cryptococcus neoformans. A murine transgenic model
-
Gyetko MR, Chen GH, McDonald RA, Goodman R, Huffnagle GB, Wilkinson CC, Fuller JA, and Toews GB (1996). Urokinase is required for the pulmonary inflammatory response to Cryptococcus neoformans. A murine transgenic model. J Clin Invest 97, 1818-1826.
-
(1996)
J Clin Invest
, vol.97
, pp. 1818-1826
-
-
Gyetko, M.R.1
Chen, G.H.2
McDonald, R.A.3
Goodman, R.4
Huffnagle, G.B.5
Wilkinson, C.C.6
Fuller, J.A.7
Toews, G.B.8
-
28
-
-
0024510367
-
Multistage carcinogenesis induced by ras and myc oncogenes in a reconstituted organ
-
Thompson TC, Southgate J, Kitchener G, and Land H (1989). Multistage carcinogenesis induced by ras and myc oncogenes in a reconstituted organ. Cell 56, 917-930.
-
(1989)
Cell
, vol.56
, pp. 917-930
-
-
Thompson, T.C.1
Southgate, J.2
Kitchener, G.3
Land, H.4
-
29
-
-
0029064620
-
Progression to androgen insensitivity in a novel in vitro mouse model for prostate cancer
-
Baley PA, Yoshida K, Qian W, Sehgal I, and Thompson TC (1995). Progression to androgen insensitivity in a novel in vitro mouse model for prostate cancer. J Steroid Biochem Mol Biol 52, 403-413.
-
(1995)
J Steroid Biochem Mol Biol
, vol.52
, pp. 403-413
-
-
Baley, P.A.1
Yoshida, K.2
Qian, W.3
Sehgal, I.4
Thompson, T.C.5
-
30
-
-
55749110745
-
Expression of the fat-1 gene diminishes prostate cancer growth in vivo through enhancing apoptosis and inhibiting GSK-3 ß phosphorylation
-
Lu Y, Nie D, Witt WT, Chen Q, Shen M, Xie H, Lai L, Dai Y, and Zhang J (2008). Expression of the fat-1 gene diminishes prostate cancer growth in vivo through enhancing apoptosis and inhibiting GSK-3 ß phosphorylation. Mol Cancer Ther 7, 3203-3211.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 3203-3211
-
-
Lu, Y.1
Nie, D.2
Witt, W.T.3
Chen, Q.4
Shen, M.5
Xie, H.6
Lai, L.7
Dai, Y.8
Zhang, J.9
-
31
-
-
2442505682
-
Pericellular proteolysis by leukocytes and tumor cells on substrates: Focal activation and the role of urokinasetype plasminogen activator
-
Kindzelskii AL, Amhad I, Keller D, Zhou MJ, Haugland RP, Garni-Wagner BA, Gyetko MR, Todd RF III, and Petty HR (2004). Pericellular proteolysis by leukocytes and tumor cells on substrates: focal activation and the role of urokinasetype plasminogen activator. Histochem Cell Biol 121, 299-310.
-
(2004)
Histochem Cell Biol
, vol.121
, pp. 299-310
-
-
Kindzelskii, A.L.1
Amhad, I.2
Keller, D.3
Zhou, M.J.4
Haugland, R.P.5
Garni-Wagner, B.A.6
Gyetko, M.R.7
Todd III, R.F.8
Petty, H.R.9
-
32
-
-
70349504369
-
A novel model of bone-metastatic prostate cancer in immunocompetent mice
-
Power CA, Pwint H, Chan J, Cho J, Yu Y, Walsh W, and Russell PJ (2009). A novel model of bone-metastatic prostate cancer in immunocompetent mice. Prostate 69, 1613-1623.
-
(2009)
Prostate
, vol.69
, pp. 1613-1623
-
-
Power, C.A.1
Pwint, H.2
Chan, J.3
Cho, J.4
Yu, Y.5
Walsh, W.6
Russell, P.J.7
-
33
-
-
0019784850
-
F4/80, a monoclonal antibody directed specifically against the mouse macrophage
-
Austyn JM and Gordon S (1981). F4/80, a monoclonal antibody directed specifically against the mouse macrophage. Eur J Immunol 11, 805-815.
-
(1981)
Eur J Immunol
, vol.11
, pp. 805-815
-
-
Austyn, J.M.1
Gordon, S.2
-
34
-
-
74949099621
-
Urokinase plasminogen activator system as a potential target for cancer therapy
-
Mekkawy AH, Morris DL, and Pourgholami MH (2009). Urokinase plasminogen activator system as a potential target for cancer therapy. Future Oncol 5, 1487-1499.
-
(2009)
Future Oncol
, vol.5
, pp. 1487-1499
-
-
Mekkawy, A.H.1
Morris, D.L.2
Pourgholami, M.H.3
-
35
-
-
0034667385
-
Tumor development is retarded in mice lacking the gene for urokinase-type plasminogen activator or its inhibitor, plasminogen activator inhibitor-1
-
Gutierrez LS, Schulman A, Brito-Robinson T, Noria F, Ploplis VA, and Castellino FJ (2000). Tumor development is retarded in mice lacking the gene for urokinase-type plasminogen activator or its inhibitor, plasminogen activator inhibitor-1. Cancer Res 60, 5839-5847.
-
(2000)
Cancer Res
, vol.60
, pp. 5839-5847
-
-
Gutierrez, L.S.1
Schulman, A.2
Brito-Robinson, T.3
Noria, F.4
Ploplis, V.A.5
Castellino, F.J.6
-
36
-
-
59449107891
-
Targeted knockdown of Notch1 inhibits invasion of human prostate cancer cells concomitant with inhibition of matrix metalloproteinase-9 and urokinase plasminogen activator
-
Bin Hafeez B, Adhami VM, Asim M, Siddiqui IA, Bhat KM, Zhong W, Saleem M, Din M, Setaluri V, and Mukhtar H (2009). Targeted knockdown of Notch1 inhibits invasion of human prostate cancer cells concomitant with inhibition of matrix metalloproteinase-9 and urokinase plasminogen activator. Clin Cancer Res 15, 452-459.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 452-459
-
-
Bin Hafeez, B.1
Adhami, V.M.2
Asim, M.3
Siddiqui, I.A.4
Bhat, K.M.5
Zhong, W.6
Saleem, M.7
Din, M.8
Setaluri, V.9
Mukhtar, H.10
-
37
-
-
77749321234
-
Down-regulation of Notch-1 and Jagged-1 inhibits prostate cancer cell growth, migration and invasion, and induces apoptosis via inactivation of Akt, mTOR, and NF-κB signaling pathways
-
Wang Z, Li Y, Banerjee S, Kong D, Ahmad A, Nogueira V, Hay N, and Sarkar FH (2010). Down-regulation of Notch-1 and Jagged-1 inhibits prostate cancer cell growth, migration and invasion, and induces apoptosis via inactivation of Akt, mTOR, and NF-κB signaling pathways. J Cell Biochem 109, 726-736.
-
(2010)
J Cell Biochem
, vol.109
, pp. 726-736
-
-
Wang, Z.1
Li, Y.2
Banerjee, S.3
Kong, D.4
Ahmad, A.5
Nogueira, V.6
Hay, N.7
Sarkar, F.H.8
|