FcRγ Activation Regulates Inflammation-Associated Squamous Carcinogenesis

Cancer Cell

Volumn 17, Issue 2, 2010, Pages 121-134

  Andreu, Pauline ^a   Johansson, Magnus ^a   Affara, Nesrine I ^a   Pucci, Ferdinando ^c   Tan, Tingting ^a   Junankar, Simon ^a   Korets, Lidiya ^a   Lam, Julia ^a   Tawfik, David ^a   DeNardo, David G ^a   Naldini, Luigi ^c   de Visser, Karin E ^d   De Palma, Michele ^c   Coussens, Lisa M ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c SAN RAFFAELE SCIENTIFIC INSTITUTE   (Italy)

^d NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

CELLCYCLE; CELLIMMUNO; MOLIMMUNO

Indexed keywords

AUTOANTIBODY; FC RECEPTOR; CD11B ANTIGEN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; BONE MARROW CELL; CANCER GROWTH; CARCINOGENESIS; CHRONIC INFLAMMATION; CONTROLLED STUDY; HUMORAL IMMUNITY; INFLAMMATION; MOUSE; NONHUMAN; PRECANCER; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; ANIMAL; BIOLOGICAL MODEL; IMMUNOLOGY; MAST CELL; METABOLISM; NEOPLASM; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; PHYSIOLOGY; TRANSGENIC MOUSE; VASCULARIZATION;

ANIMALS; ANTIGENS, CD11B; B-LYMPHOCYTES; CARCINOMA, SQUAMOUS CELL; IMMUNITY, HUMORAL; MAST CELLS; MICE; MICE, TRANSGENIC; MODELS, BIOLOGICAL; MYELOID CELLS; NEOPLASMS, GLANDULAR AND EPITHELIAL; NEOVASCULARIZATION, PATHOLOGIC; RECEPTORS, IGG;

EID: 76349088502     PISSN: 15356108     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ccr.2009.12.019     Document Type: Article

References (40)

1. Arbeit J.M., Munger K., Howley P.M., and Hanahan D. Progressive squamous epithelial neoplasia in K14-human papillomavirus type 16 transgenic mice. J. Virol. 68 (1994) 4358-4368
2. Arbeit J.M., Olson D.C., and Hanahan D. Upregulation of fibroblast growth factors and their receptors during multi-stage epidermal carcinogenesis in K14-HPV16 transgenic mice. Oncogene 13 (1996) 1847-1857
3. Barbera-Guillem E., May Jr. K.F., Nyhus J.K., and Nelson M.B. Promotion of tumor invasion by cooperation of granulocytes and macrophages activated by anti-tumor antibodies. Neoplasia 1 (1999) 453-460
4. Barbera-Guillem E., Nelson M.B., Barr B., Nyhus J.K., May Jr. K.F., Feng L., and Sampsel J.W. B lymphocyte pathology in human colorectal cancer. Experimental and clinical therapeutic effects of partial B cell depletion. Cancer Immunol. Immunother. 48 (2000) 541-549
5. Baumann U., Chouchakova N., Gewecke B., Kohl J., Carroll M.C., Schmidt R.E., and Gessner J.E. Distinct tissue site-specific requirements of mast cells and complement components C3/C5a receptor in IgG immune complex-induced injury of skin and lung. J. Immunol. 167 (2001) 1022-1027
6. Bergtold A., Gavhane A., D'Agati V., Madaio M., and Clynes R. FcR-bearing myeloid cells are responsible for triggering murine lupus nephritis. J. Immunol. 177 (2006) 7287-7295
7. Brandtzaeg P., Carlsen H.S., and Halstensen T.S. The B-cell system in inflammatory bowel disease. Adv. Exp. Med. Biol. 579 (2006) 149-167
8. Chen J., Trounstine M., Alt F.W., Young F., Kurahara C., Loring J.F., and Huszar D. Immunoglobulin gene rearrangement in B cell deficient mice generated by targeted deletion of the JH locus. Int. Immunol. 5 (1993) 647-656
9. Coussens L.M., Hanahan D., and Arbeit J.M. Genetic predisposition and parameters of malignant progression in K14-HPV16 transgenic mice. Am. J. Pathol. 149 (1996) 1899-1917
10. Coussens L.M., Raymond W.W., Bergers G., Laig-Webster M., Behrendtsen O., Werb Z., Caughey G.H., and Hanahan D. Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis. Genes Dev. 13 (1999) 1382-1397
11. Coussens L.M., Tinkle C.L., Hanahan D., and Werb Z. MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis. Cell 103 (2000) 481-490
12. Dalgleish A.G., and O'Byrne K.J. Chronic immune activation and inflammation in the pathogenesis of AIDS and cancer. Adv. Cancer Res. 84 (2002) 231-276
13. Daniel D., Chiu C., Giraud E., Inoue M., Mizzen L.A., Chu N.R., and Hanahan D. CD4+ T cell-mediated antigen-specific immunotherapy in a mouse model of cervical cancer. Cancer Res. 65 (2005) 2018-2025
14. De Palma M., Mazzieri R., Politi L.S., Pucci F., Zonari E., Sitia G., Mazzoleni S., Moi D., Venneri M.A., Indraccolo S., et al. Tumor-targeted interferon-alpha delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis. Cancer Cell 14 (2008) 299-311
15. de Visser K.E., Korets L.V., and Coussens L.M. Early neoplastic progression is complement independent. Neoplasia 6 (2004) 768-776
16. de Visser K.E., Korets L.V., and Coussens L.M. De novo carcinogenesis promoted by chronic inflammation is B lymphocyte dependent. Cancer Cell 7 (2005) 411-423
17. de Visser K.E., Eichten A., and Coussens L.M. Paradoxical roles of the immune system during cancer development. Nat. Rev. Cancer 6 (2006) 24-37
18. DeNardo D.G., Baretto J.B., Andreu P., Vasquez L., Kolhatkar N., Tawfik D., and Coussens L.M. CD4+ T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages. Cancer Cell 16 (2009) 91-102
19. Giraudo E., Inoue M., and Hanahan D. An amino-bisphosphonate targets MMP-9-expressing macrophages and angiogenesis to impair cervical carcinogenesis. J. Clin. Invest. 114 (2004) 623-633
20. Gokbuget N., and Hoelzer D. Novel antibody-based therapy for acute lymphoblastic leukaemia. Best Pract. Res. Clin. Haematol. 19 (2006) 701-713
21. Gurcan H.M., Keskin D.B., Stern J.N., Nitzberg M.A., Shekhani H., and Ahmed A.R. A review of the current use of rituximab in autoimmune diseases. Int. Immunopharmacol. 9 (2009) 10-25
22. Hagemann T., Lawrence T., McNeish I., Charles K.A., Kulbe H., Thompson R.G., Robinson S.C., and Balkwill F.R. "Re-educating" tumor-associated macrophages by targeting NF-kappaB. J. Exp. Med. 205 (2008) 1261-1268
23. Junankar S.R., Eichten A., Kramer A., de Visser K.E., and Coussens L.M. Analysis of immune cell infiltrates during squamous carcinoma development. J. Investig. Dermatol. Symp. Proc. 11 (2006) 36-43
24. Lu H., Goodell V., and Disis M.L. Humoral immunity directed against tumor-associated antigens as potential biomarkers for the early diagnosis of cancer. J. Proteome Res. 7 (2008) 1388-1394
25. Lyon M.F., and Glenister P.H. A new allele sash (Wsh) at the W-locus and a spontaneous recessive lethal in mice. Genet. Res. 39 (1982) 315-322
26. Mantovani A., Allavena P., Sica A., and Balkwill F. Cancer-related inflammation. Nature 454 (2008) 436-444
27. Markiewski M.M., DeAngelis R.A., Benencia F., Ricklin-Lichtsteiner S.K., Koutoulaki A., Gerard C., Coukos G., and Lambris J.D. Modulation of the antitumor immune response by complement. Nat. Immunol. 9 (2008) 1225-1235
28. Nakayama T., Yao L., and Tosato G. Mast cell-derived angiopoietin-1 plays a critical role in the growth of plasma cell tumors. J. Clin. Invest. 114 (2004) 1317-1325
29. Nimmerjahn F., and Ravetch J.V. Fcgamma receptors as regulators of immune responses. Nat. Rev. Immunol. 8 (2008) 34-47
30. Ostrand-Rosenberg S. Immune surveillance: a balance between protumor and antitumor immunity. Curr. Opin. Genet. Dev. 18 (2008) 11-18
31. Pollard J.W. Macrophages define the invasive microenvironment in breast cancer. J. Leukoc. Biol. 84 (2008) 623-630
32. Pucci F., Venneri M.A., Biziato D., Nonis A., Moi D., Sica A., Di Serio C., Naldini L., and De Palma M. A distinguishing gene signature shared by tumor-infiltrating Tie2-expressing monocytes (TEMs), blood "resident" monocytes and embryonic macrophages suggests common functions and developmental relationships. Blood 114 (2009) 901-914
33. Shah S., Divekar A.A., Hilchey S.P., Cho H.M., Newman C.L., Shin S.U., Nechustan H., Challita-Eid P.M., Segal B.M., Yi K.H., and Rosenblatt J.D. Increased rejection of primary tumors in mice lacking B cells: inhibition of anti-tumor CTL and TH1 cytokine responses by B cells. Int. J. Cancer 117 (2005) 574-586
34. Siegel C.T., Schreiber K., Meredith S.C., Beck-Engeser G.B., Lancki D.W., Lazarski C.A., Fu Y.X., Rowley D.A., and Schreiber H. Enhanced growth of primary tumors in cancer-prone mice after immunization against the mutant region of an inherited oncoprotein. J. Exp. Med. 191 (2000) 1945-1956
35. Soucek L., Lawlor E.R., Soto D., Shchors K., Swigart L.B., and Evan G.I. Mast cells are required for angiogenesis and macroscopic expansion of Myc-induced pancreatic islet tumors. Nat. Med. 13 (2007) 1211-1218
36. Takai T. Fc receptors and their role in immune regulation and autoimmunity. J. Clin. Immunol. 25 (2005) 1-18
37. Takai T., Li M., Sylvestre D., Clynes R., and Ravetch J.V. FcR gamma chain deletion results in pleiotrophic effector cell defects. Cell 76 (1994) 519-529
38. Tan T.T., and Coussens L.M. Humoral immunity, inflammation and cancer. Curr. Opin. Immunol. 19 (2007) 209-216
39. Theoharides T.C., and Conti P. Mast cells: the Jekyll and Hyde of tumor growth. Trends Immunol. 25 (2004) 235-241
40. Zapata J.M., Llobet D., Krajewska M., Lefebvre S., Kress C.L., and Reed J.C. Lymphocyte-specific TRAF3 transgenic mice have enhanced humoral responses and develop plasmacytosis, autoimmunity, inflammation, and cancer. Blood 113 (2009) 4595-4603