Induction of interleukin-8 preserves the angiogenic response in HIF-1α-deficient colon cancer cells

Nature Medicine

Volumn 11, Issue 9, 2005, Pages 992-997

  Mizukami, Yusuke ^a   Jo, Won Seok ^a   Duerr, Eva Maria ^a   Gala, Manish ^a   Li, Jingnan ^a   Zhang, Xiaobo ^a   Zimmer, Michael A ^a   Iliopoulos, Othon ^a   Zukerberg, Lawrence R ^a   Kohgo, Yutaka ^b   Lynch, Maureen P ^a   Rueda, Bo R ^a   Chung, Daniel C ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b ASAHIKAWA MEDICAL COLLEGE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROGEN PEROXIDE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; INTERLEUKIN 8 ANTIBODY; NEUTRALIZING ANTIBODY; VASCULOTROPIN; VASCULOTROPIN ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL; CANCER INHIBITION; CELL HYPOXIA; CELL STRAIN CACO 2; COLON CANCER; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENSITY; DRUG TARGETING; GENE MUTATION; HUMAN; HUMAN CELL; KNOCKOUT GENE; MICROVASCULATURE; MOUSE; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; ONCOGENE K RAS; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; REGULATORY MECHANISM; TUMOR VASCULARIZATION; TUMOR XENOGRAFT; WILD TYPE;

ANIMALS; CELL LINE, TUMOR; COLONIC NEOPLASMS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; HYDROGEN PEROXIDE; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INTERLEUKIN-8; MICE; MICE, NUDE; NEOVASCULARIZATION, PATHOLOGIC; OXYGEN; TRANSCRIPTION FACTORS; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

ANIMALIA;

EID: 24744438663     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm1294     Document Type: Article

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