Identification of Human Proteins That Modify Misfolding and Proteotoxicity of Pathogenic Ataxin-1

PLoS Genetics

Volumn 8, Issue 8, 2012, Pages

  Petrakis, Spyros ^a   Raskó, Tamás ^a   Russ, Jenny ^a   Friedrich, Ralf P ^a   Stroedicke, Martin ^a   Riechers, Sean Patrick ^a   Muehlenberg, Katja ^a   Möller, Angeli ^a   Reinhardt, Anita ^b   Vinayagam, Arunachalam ^a   Schaefer, Martin H ^a   Boutros, Michael ^c   Tricoire, Hervé ^b   Andrade Navarro, Miguel A ^a   Wanker, Erich E ^a  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b Groupe Hospitalier Pitié Salpêtrière   (France)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMTOLMETIN GUACIL; ATAXIN 1; CARRIER PROTEINS AND BINDING PROTEINS; POLYGLUTAMINE; PROTEIN PUM1; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; CELL ASSAY; CONTROLLED STUDY; IN VITRO STUDY; IN VIVO STUDY; MAMMAL CELL; PROTEIN AGGREGATION; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; RNA INTERFERENCE; SEQUENCE ANALYSIS; STRUCTURE ACTIVITY RELATION; WILD TYPE;

ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; ESCHERICHIA COLI; HUMANS; MEDIATOR COMPLEX; MUTATION; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PEPTIDES; PLASMIDS; POLYMERIZATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; RNA-BINDING PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

MAMMALIA;

EID: 84866149952     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002897     Document Type: Article

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