Assessing the efficacy of the hedgehog pathway inhibitor vitamin D3 in a murine xenograft model for pancreatic cancer

Cancer Biology and Therapy

Volumn 10, Issue 1, 2010, Pages 79-88

  Brüggemann, Lois W ^a   Queiroz, Karla C S ^a   Zamani, Khatera ^a   Van Straaten, Amber ^a   Spek, C Arnold ^a   Bijlsma, Maarten F ^b  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cancer; Development; Hedgehog; Murine orthotopic pancreatic adenocarcinoma model; Vitamin D3

Indexed keywords

AMYLASE; COLECALCIFEROL; COLECALCIFEROL RECEPTOR; CYCLOPAMINE; FLUOROURACIL; GEMCITABINE; GLUCOSE; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; CALCITRIOL RECEPTOR; G PROTEIN COUPLED RECEPTOR; SMO PROTEIN, HUMAN;

ADENOCARCINOMA; AMYLASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG MEGADOSE; GLUCOSE BLOOD LEVEL; IRRADIATION; MOUSE; NONHUMAN; PANCREAS CANCER; RECEPTOR UPREGULATION; TUMOR XENOGRAFT; WESTERN BLOTTING; ANIMAL; ANIMAL EMBRYO; CELL LINE; CHICKEN; CHORIOALLANTOIS; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; DRUG SCREENING; FIBROBLAST; HUMAN; METABOLISM; MOUSE MUTANT; NONOBESE DIABETIC MOUSE; PANCREAS TUMOR; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ADENOCARCINOMA; ANIMALS; BLOTTING, WESTERN; CELL LINE; CELL PROLIFERATION; CHICKENS; CHOLECALCIFEROL; CHORIOALLANTOIC MEMBRANE; EMBRYO, MAMMALIAN; FIBROBLASTS; HEDGEHOG PROTEINS; HUMANS; MICE; MICE, INBRED NOD; MICE, KNOCKOUT; MICE, SCID; PANCREATIC NEOPLASMS; RECEPTORS, CALCITRIOL; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 77954401002     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.10.1.12165     Document Type: Article

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