Gli3 mediates cell survival and sensitivity to cyclopamine in pancreatic cancer

Cancer Biology and Therapy

Volumn 10, Issue 9, 2010, Pages 893-902

  Steg, Adam ^a   Amm, Hope M ^a   Novak, Zdenek ^b   Frost, Andra R ^c   Johnson, Martin R ^a,d  

^a University of Alabama at Birmingham   (United States)

^b University of Alabama at Birmingham   (United States)

^c University of Alabama at Birmingham   (United States)

^d UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Cyclopamine; Gli3; Hedgehog; Pancreatic adenocarcinoma

Indexed keywords

CYCLOPAMINE; TRANSCRIPTION FACTOR GLI3;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL MEMBRANE DEPOLARIZATION; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CORRELATION ANALYSIS; DRUG SENSITIVITY; GENE EXPRESSION; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE; PANCREAS CANCER;

ADENOCARCINOMA; ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; BROMODEOXYURIDINE; CASPASES; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DRUG RESISTANCE, NEOPLASM; FLOW CYTOMETRY; GENE EXPRESSION; GENE KNOCKDOWN TECHNIQUES; HEDGEHOG PROTEINS; HUMANS; INHIBITORY CONCENTRATION 50; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MEMBRANE POTENTIAL, MITOCHONDRIAL; NERVE TISSUE PROTEINS; PANCREATIC NEOPLASMS; POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; VERATRUM ALKALOIDS;

EID: 78549253902     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.10.9.13252     Document Type: Article

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