-
1
-
-
1842839986
-
Expression of the PTCH1 tumor suppressor gene is regulated by alternative promoters and a single functional Gli-binding site
-
DOI 10.1016/j.gene.2004.01.010, PII S0378111904000368
-
Agren M, Kogerman P, Kleman MI, Wessling M, Toftgard R. (2004). Expression of the PTCH1 tumor suppressor gene is regulated by alternative promoters and a single functional Gli-binding site. Gene 330: 101-114. (Pubitemid 38490423)
-
(2004)
Gene
, vol.330
, Issue.1-2
, pp. 101-114
-
-
Agren, M.1
Kogerman, P.2
Kleman, M.I.3
Wessling, M.4
Toftgard, R.5
-
2
-
-
33745675445
-
Gastric mucin phenotype defines tumour progression and prognosis of intrahepatic cholangiocarcinoma: Gastric foveolar type is associated with aggressive tumour behaviour
-
DOI 10.1111/j.1365-2559.2006.02414.x
-
Aishima S, Kuroda Y, Nishihara Y, Taguchi K, Taketomi A, Maehara Y et al. (2006). Gastric mucin phenotype defines tumour progression and prognosis of intrahepatic cholangiocarcinoma: gastric foveolar type is associated with aggressive tumour behaviour. Histopathology 49: 35-44. (Pubitemid 43972918)
-
(2006)
Histopathology
, vol.49
, Issue.1
, pp. 35-44
-
-
Aishima, S.1
Kuroda, Y.2
Nishihara, Y.3
Taguchi, K.4
Taketomi, A.5
Maehara, Y.6
Tsuneyoshi, M.7
-
3
-
-
1642392438
-
Epithelial-Cadherin and β-Catenin Expression Changes in Pancreatic Intraepithelial Neoplasia
-
DOI 10.1158/1078-0432.CCR-03-0087
-
Al-Aynati MM, Radulovich N, Riddell RH, Tsao MS. (2004). Epithelial-cadherin and beta-catenin expression changes in pancreatic intraepithelial neoplasia. Clin Cancer Res 10: 1235-1240. (Pubitemid 38365212)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.4
, pp. 1235-1240
-
-
Al-Aynati, M.M.1
Radulovich, N.2
Riddell, R.H.3
Tsao, M.-S.4
-
4
-
-
77952668655
-
Membrane-bound mucins: The mechanistic basis for alterations in the growth and survival of cancer cells
-
Bafna S, Kaur S, Batra SK. (2010). Membrane-bound mucins: the mechanistic basis for alterations in the growth and survival of cancer cells. Oncogene 29: 2893-2904.
-
(2010)
Oncogene
, vol.29
, pp. 2893-2904
-
-
Bafna, S.1
Kaur, S.2
Batra, S.K.3
-
5
-
-
0242268525
-
Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours
-
DOI 10.1038/nature01972
-
Berman DM, Karhadkar SS, Maitra A, Montes De Oca R, Gerstenblith MR, Briggs K et al. (2003). Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours. Nature 425: 846-851. (Pubitemid 37351469)
-
(2003)
Nature
, vol.425
, Issue.6960
, pp. 846-851
-
-
Berman, D.M.1
Karhadkar, S.S.2
Maitra, A.3
De Oca, R.M.4
Gerstenblith, M.R.5
Briggs, K.6
Parker, A.R.7
Shimada, Y.8
Eshleman, J.R.9
Watkins, D.N.10
Beachy, P.A.11
-
6
-
-
0141675097
-
Prognostic value of serum MUC5AC mucin in patients with cholangiocarcinoma
-
DOI 10.1002/cncr.11652
-
Boonla C, Wongkham S, Sheehan JK, Wongkham C, Bhudhisawasdi V, Tepsiri N et al. (2003). Prognostic value of serum MUC5AC mucin in patients with cholangiocarcinoma. Cancer 98: 1438-1443. (Pubitemid 37151499)
-
(2003)
Cancer
, vol.98
, Issue.7
, pp. 1438-1443
-
-
Boonla, C.1
Wongkham, S.2
Sheehan, J.K.3
Wongkham, C.4
Bhudhisawasdi, V.5
Tepsiri, N.6
Pairojkul, C.7
-
7
-
-
57649210722
-
Prognostic molecular markers in cholangiocarcinoma: A systematic review
-
Briggs CD, Neal CP, Mann CD, Steward WP, Manson MM, Berry DP. (2009). Prognostic molecular markers in cholangiocarcinoma: a systematic review. Eur J Cancer 45: 33-47.
-
(2009)
Eur J Cancer
, vol.45
, pp. 33-47
-
-
Briggs, C.D.1
Neal, C.P.2
Mann, C.D.3
Steward, W.P.4
Manson, M.M.5
Berry, D.P.6
-
8
-
-
33646111185
-
Overlapping and distinct transcriptional regulator properties of the GLI1 and GLI2 oncogenes
-
Eichberger T, Sander V, Schnidar H, Regl G, Kasper M, Schmid C et al. (2006). Overlapping and distinct transcriptional regulator properties of the GLI1 and GLI2 oncogenes. Genomics 87: 616-632.
-
(2006)
Genomics
, vol.87
, pp. 616-632
-
-
Eichberger, T.1
Sander, V.2
Schnidar, H.3
Regl, G.4
Kasper, M.5
Schmid, C.6
-
9
-
-
14944346911
-
Physical and functional association of migfilin with cell-cell adhesions
-
DOI 10.1242/jcs.01638
-
Gkretsi V, Zhang Y, Tu Y, Chen K, Stolz DB, Yang Y et al. (2005). Physical and functional association of migfilin with cell-cell adhesions. J Cell Sci 118: 697-710. (Pubitemid 40372579)
-
(2005)
Journal of Cell Science
, vol.118
, Issue.4
, pp. 697-710
-
-
Gkretsi, V.1
Zhang, Y.2
Tu, Y.3
Chen, K.4
Stolz, D.B.5
Yang, Y.6
Watkins, S.C.7
Wu, C.8
-
10
-
-
0347123435
-
Mucins in cancer: Protection and control of the cell surface
-
Hollingsworth MA, Swanson BJ. (2004). Mucins in cancer: protection and control of the cell surface. Nat Rev Cancer 4: 45-60. (Pubitemid 38082153)
-
(2004)
Nature Reviews Cancer
, vol.4
, Issue.1
, pp. 45-60
-
-
Hollingsworth, M.A.1
Swanson, B.J.2
-
11
-
-
0037168129
-
kip, but does not activate mitogen-activated kinase or protein kinase B/Akt pathways
-
DOI 10.1038/sj.onc.1205970
-
Jepson S, Komatsu M, Haq B, Arango ME, Huang D, Carraway CA et al. (2002). Muc4/sialomucin complex, the intramembrane ErbB2 ligand, induces specific phosphorylation of ErbB2 and enhances expression of p27(kip), but does not activate mitogen-activated kinase or protein kinaseB/Akt pathways. Oncogene 21: 7524-7532. (Pubitemid 35305580)
-
(2002)
Oncogene
, vol.21
, Issue.49
, pp. 7524-7532
-
-
Jepson, S.1
Komatsu, M.2
Haq, B.3
Arango, M.E.4
Huang, D.5
Carothers Carraway, C.A.6
Carraway, K.L.7
-
12
-
-
0347623882
-
The G12 family of heterotrimeric G proteins and Rho GTPase mediate Sonic hedgehog signalling
-
DOI 10.1111/j.1356-9597.2004.00701.x
-
Kasai K, Takahashi M, Osumi N, Sinnarajah S, Takeo T, Ikeda H et al. (2004). The G12 family of heterotrimeric G proteins and Rho GTPase mediate Sonic hedgehog signalling. Genes Cells 9: 49-58. (Pubitemid 38180881)
-
(2004)
Genes to Cells
, vol.9
, Issue.1
, pp. 49-58
-
-
Kasai, K.1
Takahashi, M.2
Osumi, N.3
Sinnarajah, S.4
Takeo, T.5
Ikeda, H.6
Kehrl, J.H.7
Itoh, G.8
Arnheiter, H.9
-
13
-
-
54249162413
-
SCL/TAL1 interrupting locus derepresses GLI1 from the negative control of suppressor-of-fused in pancreatic cancer cell
-
Kasai K, Inaguma S, Yoneyama A, Yoshikawa K, Ikeda H. (2008). SCL/TAL1 interrupting locus derepresses GLI1 from the negative control of suppressor-of-fused in pancreatic cancer cell. Cancer Res 68: 7723-7729.
-
(2008)
Cancer Res
, vol.68
, pp. 7723-7729
-
-
Kasai, K.1
Inaguma, S.2
Yoneyama, A.3
Yoshikawa, K.4
Ikeda, H.5
-
14
-
-
33746951471
-
Selective modulation of hedgehog/GLI target gene expression by epidermal growth factor signaling in human keratinocytes
-
DOI 10.1128/MCB.02317-05
-
Kasper M, Schnidar H, Neill GW, Hanneder M, Klingler S, Blaas L et al. (2006). Selective modulation of Hedgehog/GLI target gene expression by epidermal growth factor signaling in human keratinocytes. Mol Cell Biol 26: 6283-6298. (Pubitemid 44204544)
-
(2006)
Molecular and Cellular Biology
, vol.26
, Issue.16
, pp. 6283-6298
-
-
Kasper, M.1
Schnidar, H.2
Neill, G.W.3
Hanneder, M.4
Klingler, S.5
Blaas, L.6
Schmid, C.7
Hauser-Kronberger, C.8
Regl, G.9
Philpott, M.P.10
Aberger, F.11
-
15
-
-
0035883673
-
MUC1, MUC2, MUC5AC, and MUC6 expressions in gastric carcinomas: Their roles as prognostic indicators
-
DOI 10.1002/1097-0142(20010915)92:6<1427::AID-CNCR1466>3.0.CO;2-L
-
Lee HS, Lee HK, Kim HS, Yang HK, Kim YI, Kim WH. (2001). MUC1, MUC2, MUC5AC, and MUC6 expressions in gastric carcinomas: their roles as prognostic indicators. Cancer 92: 1427-1434. (Pubitemid 32947826)
-
(2001)
Cancer
, vol.92
, Issue.6
, pp. 1427-1434
-
-
Lee, H.S.1
Lee, H.K.2
Kim, H.S.3
Yang, H.K.4
Kim, Y.I.5
Kim, W.H.6
-
16
-
-
0032549673
-
Cloning of the amino-terminal and 5'-flanking region of the human MUC5AC mucin gene and transcriptional up-regulation by bacterial exoproducts
-
DOI 10.1074/jbc.273.12.6812
-
0-flanking region of the human MUC5AC mucin gene and transcriptional up-regulation by bacterial exoproducts. J Biol Chem 273: 6812-6820. (Pubitemid 28160344)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.12
, pp. 6812-6820
-
-
Li, D.1
Gallup, M.2
Fan, N.3
Szymkowski, D.E.4
Basbaum, C.B.5
-
17
-
-
58149506283
-
GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation
-
Nolan-Stevaux O, Lau J, Truitt ML, Chu GC, Hebrok M, Fernandez-Zapico ME et al. (2009). GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation. Genes Dev 23: 24-36.
-
(2009)
Genes Dev
, vol.23
, pp. 24-36
-
-
Nolan-Stevaux, O.1
Lau, J.2
Truitt, M.L.3
Chu, G.C.4
Hebrok, M.5
Fernandez-Zapico, M.E.6
-
18
-
-
39649119479
-
Aberrant expression of SOX2 upregulates MUC5AC gastric foveolar mucin in mucinous cancers of the colorectum and related lesions
-
DOI 10.1002/ijc.23225
-
Park ET, Gum JR, Kakar S, Kwon SW, Deng G, Kim YS. (2008). Aberrant expression of SOX2 upregulates MUC5AC gastric foveolar mucin in mucinous cancers of the colorectum and related lesions. Int J Cancer 122: 1253-1260. (Pubitemid 351287224)
-
(2008)
International Journal of Cancer
, vol.122
, Issue.6
, pp. 1253-1260
-
-
Park, E.T.1
Gum, J.R.2
Kakar, S.3
Kwon, S.W.4
Deng, G.5
Kim, Y.S.6
-
19
-
-
33751209187
-
Hedgehog/Ras interactions regulate early stages of pancreatic cancer
-
DOI 10.1101/gad.1470806
-
Pasca di Magliano M, Sekine S, Ermilov A, Ferris J, Dlugosz AA, Hebrok M. (2006). Hedgehog/Ras interactions regulate early stages of pancreatic cancer. Genes Dev 20: 3161-3173. (Pubitemid 44790630)
-
(2006)
Genes and Development
, vol.20
, Issue.22
, pp. 3161-3173
-
-
Di Magliano, M.P.1
Sekine, S.2
Ermilov, A.3
Ferris, J.4
Dlugosz, A.A.5
Hebrok, M.6
-
20
-
-
16444378654
-
Gene expression profiles in pancreatic intraepithelial neoplasia reflect the effects of Hedgehog signaling on pancreatic ductal epithelial cells
-
DOI 10.1158/0008-5472.CAN-04-1413
-
Prasad NB, Biankin AV, Fukushima N, Maitra A, Dhara S, Elkahloun AG et al. (2005). Gene expression profiles in pancreatic intraepithelial neoplasia reflect the effects of Hedgehog signaling on pancreatic ductal epithelial cells. Cancer Res 65: 1619-1626. (Pubitemid 40478583)
-
(2005)
Cancer Research
, vol.65
, Issue.5
, pp. 1619-1626
-
-
Prasad, N.B.1
Biankin, A.V.2
Fukushima, N.3
Maitra, A.4
Dhara, S.5
Elkahloun, A.G.6
Hruban, R.H.7
Goggins, M.8
Leach, S.D.9
-
21
-
-
33646051846
-
Histopathologic evaluation of stepwise progression of pancreatic carcinoma with immunohistochemical analysis of gastric epithelial transcription factor SOX2: Comparison of expression patterns between invasive components and cancerous or non-neoplastic intraductal components
-
Sanada Y, Yoshida K, Ohara M, Oeda M, Konishi K, Tsutani Y. (2006). Histopathologic evaluation of stepwise progression of pancreatic carcinoma with immunohistochemical analysis of gastric epithelial transcription factor SOX2: comparison of expression patterns between invasive components and cancerous or non-neoplastic intraductal components. Pancreas 32: 164-170.
-
(2006)
Pancreas
, vol.32
, pp. 164-170
-
-
Sanada, Y.1
Yoshida, K.2
Ohara, M.3
Oeda, M.4
Konishi, K.5
Tsutani, Y.6
-
22
-
-
0035918199
-
Transgenic MUC1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation in the mouse mammary gland
-
Schroeder JA, Thompson MC, Gardner MM, Gendler SJ. (2001). Transgenic MUC1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation in the mouse mammary gland. J Biol Chem 276: 13057-13064.
-
(2001)
J Biol Chem
, vol.276
, pp. 13057-13064
-
-
Schroeder, J.A.1
Thompson, M.C.2
Gardner, M.M.3
Gendler, S.J.4
-
23
-
-
58149291766
-
The MUC gene family: Their role in the diagnosis and prognosis of gastric cancer
-
Senapati S, Sharma P, Bafna S, Roy HK, Batra SK. (2008). The MUC gene family: their role in the diagnosis and prognosis of gastric cancer. Histol Histopathol 23: 1541-1552.
-
(2008)
Histol Histopathol
, vol.23
, pp. 1541-1552
-
-
Senapati, S.1
Sharma, P.2
Bafna, S.3
Roy, H.K.4
Batra, S.K.5
-
24
-
-
0141919600
-
Involvement of the FGF18 gene in colorectal carcinogenesis, as a novel downstream target of the β-catenin/T-cell factor complex
-
Shimokawa T, Furukawa Y, Sakai M, Li M, Miwa N, Lin YM et al. (2003). Involvement of the FGF18 gene in colorectal carcinogenesis, as a novel downstream target of the beta-catenin/T-cell factor complex. Cancer Res 63: 6116-6120. (Pubitemid 37255147)
-
(2003)
Cancer Research
, vol.63
, Issue.19
, pp. 6116-6120
-
-
Shimokawa, T.1
Furukawa, Y.2
Sakai, M.3
Li, M.4
Miwa, N.5
Lin, Y.-M.6
Nakamura, Y.7
-
25
-
-
0033545845
-
The cyclin D1 gene is a target of the β-catenin/LEF-1 pathway
-
DOI 10.1073/pnas.96.10.5522
-
Shtutman M, Zhurinsky J, Simcha I, Albanese C, D'Amico M, Pestell R et al. (1999). The cyclin D1 gene is a target of the beta-catenin/ LEF-1 pathway. Proc Natl Acad Sci USA 96: 5522-5527. (Pubitemid 29234650)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.10
, pp. 5522-5527
-
-
Shtutman, M.1
Zhurinsky, J.2
Simcha, I.3
Albanese, C.4
D'Amico, M.5
Pestell, R.6
Ben-Ze'ev, A.7
-
26
-
-
54349122044
-
Clinical potential of mucins in diagnosis, prognosis, and therapy of ovarian cancer
-
Singh AP, Senapati S, Ponnusamy MP, Jain M, Lele SM, Davis JS et al. (2008). Clinical potential of mucins in diagnosis, prognosis, and therapy of ovarian cancer. Lancet Oncol 9: 1076-1085.
-
(2008)
Lancet Oncol
, vol.9
, pp. 1076-1085
-
-
Singh, A.P.1
Senapati, S.2
Ponnusamy, M.P.3
Jain, M.4
Lele, S.M.5
Davis, J.S.6
-
27
-
-
66149100988
-
Associations between selected biomarkers and prognosis in a population-based pancreatic cancer tissue microarray
-
Takikita M, Altekruse S, Lynch CF, Goodman MT, Hernandez BY, Green M et al. (2009). Associations between selected biomarkers and prognosis in a population-based pancreatic cancer tissue microarray. Cancer Res 69: 2950-2955.
-
(2009)
Cancer Res
, vol.69
, pp. 2950-2955
-
-
Takikita, M.1
Altekruse, S.2
Lynch, C.F.3
Goodman, M.T.4
Hernandez, B.Y.5
Green, M.6
-
28
-
-
0242270878
-
Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis
-
DOI 10.1038/nature02009
-
Thayer SP, di Magliano MP, Heiser PW, Nielsen CM, Roberts DJ, Lauwers GY et al. (2003). Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis. Nature 425: 851-856. (Pubitemid 37355945)
-
(2003)
Nature
, vol.425
, Issue.6960
, pp. 851-856
-
-
Thayer, S.P.1
Di Magliano, M.P.2
Heiser, P.W.3
Nielsen, C.M.4
Roberts, D.J.5
Lauwers, G.Y.6
Qi, Y.P.7
Gysin, S.8
Fernandez-Del Castillo, C.9
Yajnik, V.10
Antoniu, B.11
McMahon, M.12
Warshaw, A.L.13
Hebrok, M.14
-
29
-
-
0345269741
-
Requirement of both mucins and proteoglycans in cell-cell dissociation and invasiveness of colon carcinoma HT-29 cells
-
DOI 10.1002/ijc.11011
-
Truant S, Bruyneel E, Gouyer V, De Wever O, Pruvot FR, Mareel M et al. (2003). Requirement of both mucins and proteoglycans in cell-cell dissociation and invasiveness of colon carcinoma HT-29 cells. Int J Cancer 104: 683-694. (Pubitemid 36418504)
-
(2003)
International Journal of Cancer
, vol.104
, Issue.6
, pp. 683-694
-
-
Truant, S.1
Bruyneel, E.2
Gouyer, V.3
De Wever, O.4
Pruvot, F.-R.5
Mareel, M.6
Huet, G.7
-
30
-
-
34948824382
-
Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells
-
DOI 10.1038/sj.onc.1210479, PII 1210479
-
Vincent A, Perrais M, Desseyn JL, Aubert JP, Pigny P, Van Seuningen I. (2007). Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells. Oncogene 26: 6566-6576. (Pubitemid 47530602)
-
(2007)
Oncogene
, vol.26
, Issue.45
, pp. 6566-6576
-
-
Vincent, A.1
Perrais, M.2
Desseyn, J.-L.3
Aubert, J.-P.4
Pigny, P.5
Van Seuningen, I.6
-
31
-
-
0141733054
-
Nuclear association of the cytoplasmic tail of MUC1 and β-catenin
-
DOI 10.1074/jbc.M304333200
-
Wen Y, Caffrey TC, Wheelock MJ, Johnson KR, Hollingsworth MA. (2003). Nuclear association of the cytoplasmic tail of MUC1 and beta-catenin. J Biol Chem 278: 38029-38039. (Pubitemid 37175334)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.39
, pp. 38029-38039
-
-
Wen, Y.1
Caffrey, T.C.2
Wheelock, M.J.3
Johnson, K.R.4
Hollingsworth, M.A.5
-
32
-
-
52149119128
-
A paracrine requirement for hedgehog signalling in cancer
-
Yauch RL, Gould SE, Scales SJ, Tang T, Tian H, Ahn CP et al. (2008). A paracrine requirement for hedgehog signalling in cancer. Nature 455: 406-410.
-
(2008)
Nature
, vol.455
, pp. 406-410
-
-
Yauch, R.L.1
Gould, S.E.2
Scales, S.J.3
Tang, T.4
Tian, H.5
Ahn, C.P.6
-
33
-
-
0037085379
-
Gene expression profiling leads to identification of GLI1-binding elements in target genes and a role for multiple downstream pathways in GLI1-induced cell transformation
-
DOI 10.1074/jbc.M105708200
-
Yoon JW, Kita Y, Frank DJ, Majewski RR, Konicek BA, Nobrega MA et al. (2002). Gene expression profiling leads to identification of GLI1-binding elements in target genes and a role for multiple downstream pathways in GLI1-induced cell transformation. J Biol Chem 277: 5548-5555. (Pubitemid 34968606)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.7
, pp. 5548-5555
-
-
Yoon, J.W.1
Kita, Y.2
Frank, D.J.3
Majewski, R.R.4
Konicek, B.A.5
Nobrega, M.A.6
Jacob, H.7
Walterhouse, D.8
Iannaccone, P.9
-
34
-
-
0030450545
-
Overexpression of MUC5 genes is associated with early postoperative metastasis in non-small-cell lung cancer
-
Yu CJ, Yang PC, Shun CT, Lee YC, Kuo SH, Luh KT. (1996). Overexpression of MUC5 genes is associated with early postoperative metastasis in non-small-cell lung cancer. Int J Cancer 69: 457-465.
-
(1996)
Int J Cancer
, vol.69
, pp. 457-465
-
-
Yu, C.J.1
Yang, P.C.2
Shun, C.T.3
Lee, Y.C.4
Kuo, S.H.5
Luh, K.T.6
-
35
-
-
10444233473
-
Sialyl Lewis antigens: Association with MUC5AC protein and correlation with post-operative recurrence of non-small cell lung cancer
-
DOI 10.1016/j.lungcan.2004.05.018, PII S0169500204002594
-
Yu CJ, Shih JY, Lee YC, Shun CT, Yuan A, Yang PC. (2005). Sialyl Lewis antigens: association with MUC5AC protein and correlation with post-operative recurrence of non-small cell lung cancer. Lung Cancer 47: 59-67. (Pubitemid 39643242)
-
(2005)
Lung Cancer
, vol.47
, Issue.1
, pp. 59-67
-
-
Yu, C.-J.1
Shih, J.-Y.2
Lee, Y.-C.3
Shun, C.-T.4
Yuan, A.5
Yang, P.-C.6
|