메뉴 건너뛰기




Volumn 342, Issue 3, 2012, Pages 598-607

Mitochondrial function and dysfunction: An update

Author keywords

[No Author keywords available]

Indexed keywords

4 [4 (4' CHLORO 2 BIPHENYLYLMETHYL) 1 PIPERAZINYL] N [4 [3 DIMETHYLAMINO 1 (PHENYLTHIOMETHYL)PROPYLAMINO] 3 NITROBENZENESULFONYL]BENZAMIDE; ADENOSINE TRIPHOSPHATE; ALPHA TOCOPHEROL; BICARBONATE; CARNITINE; CHOLINE TETRATHIOMOLYBDATE; COCARBOXYLASE; CREATINE; DEOXYCORTICOSTERONE ACETATE; DICHLOROACETIC ACID; DOCOSAHEXAENOIC ACID; ELESCLOMOL; FOLIC ACID; ICOSAPENTAENOIC ACID; ISOSORBIDE; LACTIC ACID; METHYLENE BLUE; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; NANOPARTICLE; NATURAL PRODUCT; NUTRACEUTICAL; PYRUVIC ACID; REACTIVE OXYGEN METABOLITE; RIBOFLAVIN; SUCCINIC ACID; TETRAHYDROLIPSTATIN; TROLOX C; UBIDECARENONE; UNINDEXED DRUG; VITAMIN D;

EID: 84865165560     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.112.192104     Document Type: Review
Times cited : (63)

References (97)
  • 1
    • 79960135863 scopus 로고    scopus 로고
    • Mitochondria are sources of metabolic sink and arrhythmias
    • Akar FG and O'Rourke B (2011) Mitochondria are sources of metabolic sink and arrhythmias. Pharmacol Ther 131:287-294.
    • (2011) Pharmacol Ther , vol.131 , pp. 287-294
    • Akar, F.G.1    O'Rourke, B.2
  • 2
    • 81855178288 scopus 로고    scopus 로고
    • Impact of PGC-1α on the topology and rate of superoxide production by the mitochondrial electron transport chain
    • Austin S, Klimcakova E, and St-Pierre J (2011) Impact of PGC-1α on the topology and rate of superoxide production by the mitochondrial electron transport chain. Free Radic Biol Med 51:2243-2248.
    • (2011) Free Radic Biol Med , vol.51 , pp. 2243-2248
    • Austin, S.1    Klimcakova, E.2    St-Pierre, J.3
  • 4
    • 84856770468 scopus 로고    scopus 로고
    • Role of the mitochondrion in programmed necrosis
    • Baines CP (2010) Role of the mitochondrion in programmed necrosis. Front Physiol 1:156.
    • (2010) Front Physiol , vol.1 , pp. 156
    • Baines, C.P.1
  • 5
    • 18044383110 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in cardiovascular disease
    • Ballinger SW (2005) Mitochondrial dysfunction in cardiovascular disease. Free Radic Biol Med 38:1278-12795.
    • (2005) Free Radic Biol Med , vol.38 , pp. 1278-12795
    • Ballinger, S.W.1
  • 6
    • 33750704229 scopus 로고    scopus 로고
    • A simplified model for mitochondrial ATP production
    • DOI 10.1016/j.jtbi.2006.07.019, PII S0022519306003225
    • Bertram R, Gram Pedersen M, Luciani DS, and Sherman A (2006) A simplified model for mitochondrial ATP production. J Theor Biol 243:575-586. (Pubitemid 44708225)
    • (2006) Journal of Theoretical Biology , vol.243 , Issue.4 , pp. 575-586
    • Bertram, R.1    Gram, P.M.2    Luciani, D.S.3    Sherman, A.4
  • 7
    • 79251581868 scopus 로고    scopus 로고
    • A brief history of the status of transposable elements: From junk DNA to major players in evolution
    • Biémont C (2010) A brief history of the status of transposable elements: from junk DNA to major players in evolution. Genetics 186:1085-1093.
    • (2010) Genetics , vol.186 , pp. 1085-1093
    • Biémont, C.1
  • 8
    • 77952120023 scopus 로고    scopus 로고
    • Olesoxime (TRO19622): A novel mitochondrial-targeted neuroprotective compound
    • Bordet T, Berna P, Abitbol J-L, and Pruss RM (2010) Olesoxime (TRO19622): a novel mitochondrial-targeted neuroprotective compound. Pharmaceuticals 3:345-368.
    • (2010) Pharmaceuticals , vol.3 , pp. 345-368
    • Bordet, T.1    Berna, P.2    Abitbol, J.-L.3    Pruss, R.M.4
  • 9
    • 84856108187 scopus 로고    scopus 로고
    • Opposite effects of statins on mitochondria of cardiac and skeletal muscles: A 'mitohormesis' mechanism involving reactive oxygen species and PGC-1
    • Bouitbir J, Charles A-L, Echaniz-Laguna A, Kindo M, Daussin F, Auwerx J, Piquard F, Geny B, and Zoll J (2011) Opposite effects of statins on mitochondria of cardiac and skeletal muscles: a 'mitohormesis' mechanism involving reactive oxygen species and PGC-1. Eur Heart J 33:1397-1407.
    • (2011) Eur Heart J , vol.33 , pp. 1397-1407
    • Bouitbir, J.1    Charles, A.-L.2    Echaniz-Laguna, A.3    Kindo, M.4    Daussin, F.5    Auwerx, J.6    Piquard, F.7    Geny, B.8    Zoll, J.9
  • 11
    • 33750445482 scopus 로고    scopus 로고
    • Mitochondrial fusion and fission in mammals
    • Chan DC (2006) Mitochondrial fusion and fission in mammals. Annu Rev Cell Dev Biol 22:79-99.
    • (2006) Annu Rev Cell Dev Biol , vol.22 , pp. 79-99
    • Chan, D.C.1
  • 12
    • 39649120348 scopus 로고    scopus 로고
    • Inherited mitochondrial diseases of DNA replication
    • Copeland WC (2008) Inherited mitochondrial diseases of DNA replication. Annu Rev Med 59:131-146.
    • (2008) Annu Rev Med , vol.59 , pp. 131-146
    • Copeland, W.C.1
  • 14
    • 82755165191 scopus 로고    scopus 로고
    • Aging genes: The sirtuin story unravels
    • Couzin-Frankel J (2011) Aging genes: the sirtuin story unravels. Science 334:1194-1198.
    • (2011) Science , vol.334 , pp. 1194-1198
    • Couzin-Frankel, J.1
  • 16
    • 70149084131 scopus 로고    scopus 로고
    • Mitochondrial kinases in Parkinson's disease: Converging insights from neurotoxin and genetic models
    • Dagda RK, Zhu J, and Chu CT (2009) Mitochondrial kinases in Parkinson's disease: converging insights from neurotoxin and genetic models. Mitochondrion 9:289-298.
    • (2009) Mitochondrion , vol.9 , pp. 289-298
    • Dagda, R.K.1    Zhu, J.2    Chu, C.T.3
  • 17
    • 33748755428 scopus 로고    scopus 로고
    • Therapeutic rescue of neurodegeneration in experimental type 3 diabetes: Relevance to Alzheimer's disease
    • de la Monte SM, Tong M, Lester-Coll N, Plater M Jr, and Wands JR (2006) Therapeutic rescue of neurodegeneration in experimental type 3 diabetes: relevance to Alzheimer's disease. J Alzheimers Dis 10:89-109. (Pubitemid 44401370)
    • (2006) Journal of Alzheimer's Disease , vol.10 , Issue.1 , pp. 89-109
    • De La, M.S.M.1    Tong, M.2    Lester-Coll, N.3    Plater Jr., M.4    Wands, J.R.5
  • 19
    • 47149108940 scopus 로고    scopus 로고
    • Effect of dimebon on cognition, activities of daily living, behaviour, and global function in patients with mild-to-moderate Alzheimer's disease: A randomised, double-blind, placebo-controlled study
    • DOI 10.1016/S0140-6736(08)61074-0, PII S0140673608610740
    • Doody RS, Gavrilova SI, Sano M, Thomas RG, Aisen PS, Bachurin SO, Seely L, Hung D, and dimebon investigators (2008) Effect of dimebon on cognition, activities of daily living, behaviour, and global function in patients with mild-to-moderate Alzheimer's disease: a randomised, double-blind, placebo-controlled study. Lancet 372:207-215. (Pubitemid 351978110)
    • (2008) The Lancet , vol.372 , Issue.9634 , pp. 207-215
    • Doody, R.S.1    Gavrilova, S.I.2    Sano, M.3    Thomas, R.G.4    Aisen, P.S.5    Bachurin, S.O.6    Seely, L.7    Hung, D.8
  • 20
    • 84858006015 scopus 로고    scopus 로고
    • Functionalized nanosystems for targeted mitochondrial delivery
    • Durazo SA and Kompella UB (2012) Functionalized nanosystems for targeted mitochondrial delivery. Mitochondrion 12:190-201.
    • (2012) Mitochondrion , vol.12 , pp. 190-201
    • Durazo, S.A.1    Kompella, U.B.2
  • 21
    • 78650944949 scopus 로고    scopus 로고
    • The cell-non-autonomous nature of electron transport chain-mediated longevity
    • Durieux J, Wolff S, and Dillin A (2011) The cell-non-autonomous nature of electron transport chain-mediated longevity. Cell 144:79-91.
    • (2011) Cell , vol.144 , pp. 79-91
    • Durieux, J.1    Wolff, S.2    Dillin, A.3
  • 22
    • 7744235672 scopus 로고    scopus 로고
    • Death by design: Apoptosis, necrosis and autophagy
    • DOI 10.1016/j.ceb.2004.09.011, PII S0955067404001474
    • Edinger AL and Thompson CB (2004) Death by design: apoptosis, necrosis and autophagy. Curr Opin Cell Biol 16:663-669. (Pubitemid 39463117)
    • (2004) Current Opinion in Cell Biology , vol.16 , Issue.6 , pp. 663-669
    • Edinger, A.L.1    Thompson, C.B.2
  • 23
    • 79957944105 scopus 로고    scopus 로고
    • Estrogen related receptors (ERRs): A new dawn in transcriptional control of mitochondrial gene networks
    • Eichner LJ and Giguère V (2011) Estrogen related receptors (ERRs): a new dawn in transcriptional control of mitochondrial gene networks. Mitochondrion 11:544-552.
    • (2011) Mitochondrion , vol.11 , pp. 544-552
    • Eichner, L.J.1    Giguère, V.2
  • 24
    • 79961238706 scopus 로고    scopus 로고
    • Role of Drp1, a key mitochondrial fission protein, in neuropathic pain
    • Ferrari LF, Chum A, Bogen O, Reichling DB, and Levine JD (2011) Role of Drp1, a key mitochondrial fission protein, in neuropathic pain. J Neurosci 31:11404-11410.
    • (2011) J Neurosci , vol.31 , pp. 11404-11410
    • Ferrari, L.F.1    Chum, A.2    Bogen, O.3    Reichling, D.B.4    Levine, J.D.5
  • 26
    • 71649095031 scopus 로고    scopus 로고
    • Treatment of mitochondrial disorders
    • Finsterer J (2010) Treatment of mitochondrial disorders. Eur J Paediatr Neurol 14:29-44.
    • (2010) Eur J Paediatr Neurol , vol.14 , pp. 29-44
    • Finsterer, J.1
  • 28
    • 68349125007 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis, frontotemporal dementia and beyond: The TDP-43 diseases
    • Geser F, Martinez-Lage M, Kwong LK, Lee VM, and Trojanowski JQ (2009) Amyotrophic lateral sclerosis, frontotemporal dementia and beyond: the TDP-43 diseases. J Neurol 256:1205-1214.
    • (2009) J Neurol , vol.256 , pp. 1205-1214
    • Geser, F.1    Martinez-Lage, M.2    Kwong, L.K.3    Lee, V.M.4    Trojanowski, J.Q.5
  • 29
    • 84865161315 scopus 로고    scopus 로고
    • Transgenic mouse models resistant to diet-induced metabolic disease: Is energy balance the key?
    • Gilliam LAA and Neufer PD (2012) Transgenic mouse models resistant to diet-induced metabolic disease: is energy balance the key? J Pharmacol Exp Ther 342:631-636.
    • (2012) J Pharmacol Exp Ther , vol.342 , pp. 631-636
    • Gilliam, L.A.A.1    Neufer, P.D.2
  • 32
    • 67349117275 scopus 로고    scopus 로고
    • What is the mitochondrial permeability transition pore?
    • Halestrap AP (2009) What is the mitochondrial permeability transition pore? J Mol Cell Cardiol 46:821-831.
    • (2009) J Mol Cell Cardiol , vol.46 , pp. 821-831
    • Halestrap, A.P.1
  • 33
    • 79952442409 scopus 로고    scopus 로고
    • Free radicals and antioxidants-quo vadis?
    • Halliwell B (2011) Free radicals and antioxidants-quo vadis? Trends Pharmacol Sci 32:125-130.
    • (2011) Trends Pharmacol Sci , vol.32 , pp. 125-130
    • Halliwell, B.1
  • 34
    • 78650034178 scopus 로고    scopus 로고
    • Ubiquitin/proteasome pathway impairment in neurodegeneration: Therapeutic implications
    • Huang Q and Figueiredo-Pereira ME (2010) Ubiquitin/proteasome pathway impairment in neurodegeneration: therapeutic implications. Apoptosis 15:1292-1311.
    • (2010) Apoptosis , vol.15 , pp. 1292-1311
    • Huang, Q.1    Figueiredo-Pereira, M.E.2
  • 35
    • 79953745644 scopus 로고    scopus 로고
    • The multiple functions of cytochrome c and their regulation in life and death decisions of the mammalian cell: From respiration to apoptosis
    • Hüttemann M, Pecina P, Rainbolt M, Sanderson TH, Kagan VE, Samavati L, Doan JW, and Lee I (2011) The multiple functions of cytochrome c and their regulation in life and death decisions of the mammalian cell: From respiration to apoptosis. Mitochondrion 11:369-381.
    • (2011) Mitochondrion , vol.11 , pp. 369-381
    • Hüttemann, M.1    Pecina, P.2    Rainbolt, M.3    Sanderson, T.H.4    Kagan, V.E.5    Samavati, L.6    Doan, J.W.7    Lee, I.8
  • 36
    • 79953803842 scopus 로고    scopus 로고
    • Targeting the mitochondrial permeability transition: Cardiac ischemia-reperfusion versus carcinogenesis
    • Javadov S, Hunter JC, Barreto-Torres G, and Parodi-Rullan R (2011) Targeting the mitochondrial permeability transition: cardiac ischemia-reperfusion versus carcinogenesis. Cell Physiol Biochem 27:179-190.
    • (2011) Cell Physiol Biochem , vol.27 , pp. 179-190
    • Javadov, S.1    Hunter, J.C.2    Barreto-Torres, G.3    Parodi-Rullan, R.4
  • 37
    • 84865187620 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in neurodegenerative diseases
    • Johri A and Beal MF (2012) Mitochondrial dysfunction in neurodegenerative diseases. J Pharmacol Exp Ther 342:619-630.
    • (2012) J Pharmacol Exp Ther , vol.342 , pp. 619-630
    • Johri, A.1    Beal, M.F.2
  • 38
    • 77955456084 scopus 로고    scopus 로고
    • Characterization of bioactive cell penetrating peptides from human cytochrome c: Protein mimicry and the development of a novel apoptogenic agent
    • Jones S, Holm T, Mäger I, Langel U, and Howl J (2010) Characterization of bioactive cell penetrating peptides from human cytochrome c: protein mimicry and the development of a novel apoptogenic agent. Chem Biol 17:735-744.
    • (2010) Chem Biol , vol.17 , pp. 735-744
    • Jones, S.1    Holm, T.2    Mäger, I.3    Langel, U.4    Howl, J.5
  • 39
    • 76349123010 scopus 로고    scopus 로고
    • Treatment of mitochondrial electron transport chain disorders: A review of clinical trials over the past decade
    • Kerr DS (2010) Treatment of mitochondrial electron transport chain disorders: a review of clinical trials over the past decade. Mol Genet Metab 99:246-255.
    • (2010) Mol Genet Metab , vol.99 , pp. 246-255
    • Kerr, D.S.1
  • 40
    • 77952700862 scopus 로고    scopus 로고
    • Apoptotic cell death "Nixed" by an ER mitochondrial necrotic pathway
    • Kitsis RN and Molkentin JD (2010) Apoptotic cell death "Nixed" by an ER mitochondrial necrotic pathway. Proc Natl Acad Sci U S A 107:9031-9032.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 9031-9032
    • Kitsis, R.N.1    Molkentin, J.D.2
  • 44
    • 67649359964 scopus 로고    scopus 로고
    • Soluble adenylyl cyclase controls mitochondria-dependent apoptosis in coronary endothelial cells
    • Kumar S, Kostin S, Flacke JP, Reusch HP, and Ladilov Y (2009) Soluble adenylyl cyclase controls mitochondria-dependent apoptosis in coronary endothelial cells. J Biol Chem 284:14760-14768.
    • (2009) J Biol Chem , vol.284 , pp. 14760-14768
    • Kumar, S.1    Kostin, S.2    Flacke, J.P.3    Reusch, H.P.4    Ladilov, Y.5
  • 45
    • 77953807486 scopus 로고    scopus 로고
    • Mitochondrial carriers function as monomers
    • Kunji ER and Crichton PG (2010) Mitochondrial carriers function as monomers. Biochim Biophys Acta 1797:817-831.
    • (2010) Biochim Biophys Acta , vol.1797 , pp. 817-831
    • Kunji, E.R.1    Crichton, P.G.2
  • 47
    • 73749085674 scopus 로고    scopus 로고
    • When a theory of aging ages badly
    • Lapointe J and Hekimi S (2010) When a theory of aging ages badly. Cell Mol Life Sci 67:1-8.
    • (2010) Cell Mol Life Sci , vol.67 , pp. 1-8
    • Lapointe, J.1    Hekimi, S.2
  • 48
    • 82555194263 scopus 로고    scopus 로고
    • Mitochondrial mutations: Newly discovered players in neuronal degeneration
    • Lax NZ, Turnbull DM, and Reeve AK (2011) Mitochondrial mutations: newly discovered players in neuronal degeneration. Neuroscientist 17:645-658.
    • (2011) Neuroscientist , vol.17 , pp. 645-658
    • Lax, N.Z.1    Turnbull, D.M.2    Reeve, A.K.3
  • 49
    • 77952326081 scopus 로고    scopus 로고
    • Disease-causing mutations in parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy
    • Lee JY, Nagano Y, Taylor JP, Lim KL, and Yao TP (2010) Disease-causing mutations in parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy. J Cell Biol 189:671-679.
    • (2010) J Cell Biol , vol.189 , pp. 671-679
    • Lee, J.Y.1    Nagano, Y.2    Taylor, J.P.3    Lim, K.L.4    Yao, T.P.5
  • 50
    • 3242884720 scopus 로고    scopus 로고
    • Organization and dynamics of human mitochondrial DNA
    • DOI 10.1242/jcs.01134
    • Legros F, Malka F, Frachon P, Lombès A, and Rojo M (2004) Organization and dynamics of human mitochondrial DNA. J Cell Sci 117:2653-2662. (Pubitemid 38997249)
    • (2004) Journal of Cell Science , vol.117 , Issue.13 , pp. 2653-2662
    • Legros, F.1    Malka, F.2    Frachon, P.3    Lombes, A.4    Rojo, M.5
  • 52
    • 84865177226 scopus 로고    scopus 로고
    • Warburg revisited: Regulation of mitochondrial metabolism by voltage-dependent anion channels in cancer cells
    • Maldonado EN and LeMasters JL (2012) Warburg revisited: regulation of mitochondrial metabolism by voltage-dependent anion channels in cancer cells. J Pharmacol Exp Ther 342:637-641.
    • (2012) J Pharmacol Exp Ther , vol.342 , pp. 637-641
    • Maldonado, E.N.1    LeMasters, J.L.2
  • 53
    • 78650916379 scopus 로고    scopus 로고
    • The mitochondrial permeability transition pore regulates nitric oxide-mediated apoptosis of neurons induced by target deprivation
    • Martin LJ, Adams NA, Pan Y, Price A, and Wong M (2011) The mitochondrial permeability transition pore regulates nitric oxide-mediated apoptosis of neurons induced by target deprivation. J Neurosci 31:359-370.
    • (2011) J Neurosci , vol.31 , pp. 359-370
    • Martin, L.J.1    Adams, N.A.2    Pan, Y.3    Price, A.4    Wong, M.5
  • 54
    • 33746016268 scopus 로고    scopus 로고
    • Mitochondria: More than just a powerhouse
    • McBride HM, Neuspiel M, and Wasiak S (2006) Mitochondria: more than just a powerhouse. Curr Biol 16:R551-R560.
    • (2006) Curr Biol , vol.16
    • McBride, H.M.1    Neuspiel, M.2    Wasiak, S.3
  • 55
    • 79551518229 scopus 로고    scopus 로고
    • Energy deficit in Huntington's disease: Why it matters
    • Mochel F and Haller RG (2011) Energy deficit in Huntington's disease: why it matters. J Clin Invest 121:493-499.
    • (2011) J Clin Invest , vol.121 , pp. 493-499
    • Mochel, F.1    Haller, R.G.2
  • 56
    • 71749121998 scopus 로고    scopus 로고
    • Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology
    • Moreira PI, Carvalho C, Zhu X, Smith MA, and Perry G (2010) Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology. Biochim Biophys Acta 1802:2-10.
    • (2010) Biochim Biophys Acta , vol.1802 , pp. 2-10
    • Moreira, P.I.1    Carvalho, C.2    Zhu, X.3    Smith, M.A.4    Perry, G.5
  • 57
    • 34249821079 scopus 로고    scopus 로고
    • Brain mitochondrial dysfunction as a link between Alzheimer's disease and diabetes
    • DOI 10.1016/j.jns.2007.01.017, PII S0022510X07000408, Vascular Dementia Proceedings of the Fourth International Congress on Vascular Dementia
    • Moreira PI, Santos MS, Seiça R, and Oliveira CR (2007) Brain mitochondrial dysfunction as a link between Alzheimer's disease and diabetes. J Neurol Sci 257: 206-214. (Pubitemid 46856489)
    • (2007) Journal of the Neurological Sciences , vol.257 , Issue.1-2 , pp. 206-214
    • Moreira, P.I.1    Santos, M.S.2    Seica, R.3    Oliveira, C.R.4
  • 58
    • 84863394784 scopus 로고    scopus 로고
    • Translational semantics and infrastructure: Another search for the emperor's new clothes?
    • Mullane K and Williams M (2012) Translational semantics and infrastructure: another search for the emperor's new clothes? Drug Discov Today 17:459-468.
    • (2012) Drug Discov Today , vol.17 , pp. 459-468
    • Mullane, K.1    Williams, M.2
  • 59
    • 84865182100 scopus 로고    scopus 로고
    • Oxidative shielding or oxidative stress?
    • Naviaux RK (2012) Oxidative shielding or oxidative stress? J Pharmacol Exp Ther 342:608-618.
    • (2012) J Pharmacol Exp Ther , vol.342 , pp. 608-618
    • Naviaux, R.K.1
  • 60
    • 77956795824 scopus 로고    scopus 로고
    • Mitochondrial morphology and cardiovascular disease
    • Ong SB and Hausenloy DJ (2010) Mitochondrial morphology and cardiovascular disease. Cardiovasc Res 88:16-29.
    • (2010) Cardiovasc Res , vol.88 , pp. 16-29
    • Ong, S.B.1    Hausenloy, D.J.2
  • 61
    • 84866469405 scopus 로고    scopus 로고
    • Mitochondrial DNA damage and animal longevity: Insights from comparative studies
    • Pamplona R (2011) Mitochondrial DNA damage and animal longevity: insights from comparative studies. J Aging Res 2011:807108.
    • (2011) J Aging Res , vol.2011 , pp. 807108
    • Pamplona, R.1
  • 64
    • 84855589344 scopus 로고    scopus 로고
    • Strategies for reducing or preventing the generation of oxidative stress
    • Poljsak B (2011) Strategies for reducing or preventing the generation of oxidative stress. Oxid Med Cell Longev 2011:194586.
    • (2011) Oxid Med Cell Longev , vol.2011 , pp. 194586
    • Poljsak, B.1
  • 65
    • 73349132395 scopus 로고    scopus 로고
    • The role of mitochondria in neurodegenerative diseases: Mitochondria as a therapeutic target in Alzheimer's disease
    • discussion 16-18
    • Reddy PH (2009) The role of mitochondria in neurodegenerative diseases: mitochondria as a therapeutic target in Alzheimer's disease. CNS Spectr 14:8-13; discussion 16-18.
    • (2009) CNS Spectr , vol.14 , pp. 8-13
    • Reddy, P.H.1
  • 66
    • 77957833643 scopus 로고    scopus 로고
    • Blocking the mitochondrial apoptotic pathway preserves motor neuron viability and function in a mouse model of amyotrophic lateral sclerosis
    • Reyes NA, Fisher JK, Austgen K, VandenBerg S, Huang EJ, and Oakes SA (2010) Blocking the mitochondrial apoptotic pathway preserves motor neuron viability and function in a mouse model of amyotrophic lateral sclerosis. J Clin Invest 120:3673-3679.
    • (2010) J Clin Invest , vol.120 , pp. 3673-3679
    • Reyes, N.A.1    Fisher, J.K.2    Austgen, K.3    VandenBerg, S.4    Huang, E.J.5    Oakes, S.A.6
  • 69
    • 84859005372 scopus 로고    scopus 로고
    • A review of research trends in physiological abnormalities in autism spectrum disorders: Immune dysregulation, inflammation, oxidative stress, mitochondrial dysfunction and environmental toxicant exposures
    • Rossignol DA and Frye RE (2012) A review of research trends in physiological abnormalities in autism spectrum disorders: immune dysregulation, inflammation, oxidative stress, mitochondrial dysfunction and environmental toxicant exposures. Mol Psychiatry 17:389-401.
    • (2012) Mol Psychiatry , vol.17 , pp. 389-401
    • Rossignol, D.A.1    Frye, R.E.2
  • 70
    • 77957113132 scopus 로고    scopus 로고
    • Latrepirdine for Alzheimer's disease: Trials and tribulations
    • Sabbagh MN and Berk C (2010) Latrepirdine for Alzheimer's disease: trials and tribulations. Future Neurol 5:645-665.
    • (2010) Future Neurol , vol.5 , pp. 645-665
    • Sabbagh, M.N.1    Berk, C.2
  • 72
    • 33745410626 scopus 로고    scopus 로고
    • Mitochondrial disease
    • Schapira AH (2006) Mitochondrial disease. Lancet 368:70-82.
    • (2006) Lancet , vol.368 , pp. 70-82
    • Schapira, A.H.1
  • 73
    • 34548639894 scopus 로고    scopus 로고
    • The magic garden
    • Schatz G (2007) The magic garden. Annu Rev Biochem 76:673-678.
    • (2007) Annu Rev Biochem , vol.76 , pp. 673-678
    • Schatz, G.1
  • 76
    • 78149359813 scopus 로고    scopus 로고
    • Mitochondrial fission/fusion dynamics and apoptosis
    • Sheridan C and Martin SJ (2010) Mitochondrial fission/fusion dynamics and apoptosis. Mitochondrion 10:640-648.
    • (2010) Mitochondrion , vol.10 , pp. 640-648
    • Sheridan, C.1    Martin, S.J.2
  • 77
    • 84856510610 scopus 로고    scopus 로고
    • VDAC, a multi-functional mitochondrial protein as a pharmacological target
    • Shoshan-Barmatz V and Ben-Hail D (2012) VDAC, a multi-functional mitochondrial protein as a pharmacological target. Mitochondrion 12:24-34.
    • (2012) Mitochondrion , vol.12 , pp. 24-34
    • Shoshan-Barmatz, V.1    Ben-Hail, D.2
  • 79
    • 79961209538 scopus 로고    scopus 로고
    • Why are there no proven therapies for genetic mitochondrial diseases?
    • Stacpoole PW (2011) Why are there no proven therapies for genetic mitochondrial diseases? Mitochondrion 11:679-685.
    • (2011) Mitochondrion , vol.11 , pp. 679-685
    • Stacpoole, P.W.1
  • 80
    • 84862907788 scopus 로고    scopus 로고
    • Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase
    • Sun L, Wang H, Wang Z, He S, Chen S, Liao D, Wang L, Yan J, Liu W, Lei X, et al. (2012) Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase. Cell 148:213-227.
    • (2012) Cell , vol.148 , pp. 213-227
    • Sun, L.1    Wang, H.2    Wang, Z.3    He, S.4    Chen, S.5    Liao, D.6    Wang, L.7    Yan, J.8    Liu, W.9    Lei, X.10
  • 81
    • 77954889694 scopus 로고    scopus 로고
    • NSAIDs, mitochondria and calcium signaling: Special focus on aspirin/salicylates
    • Suzuki Y, Inoue T, and Ra C (2010) NSAIDs, mitochondria and calcium signaling: special focus on aspirin/salicylates. Pharmaceuticals 3:1594-1613.
    • (2010) Pharmaceuticals , vol.3 , pp. 1594-1613
    • Suzuki, Y.1    Inoue, T.2    Ra, C.3
  • 82
    • 67649687124 scopus 로고    scopus 로고
    • The Alzheimer's disease mitochondrial cascade hypothesis: An update
    • Swerdlow RH and Khan SM (2009) The Alzheimer's disease mitochondrial cascade hypothesis: an update. Exp Neurol 218:308-315.
    • (2009) Exp Neurol , vol.218 , pp. 308-315
    • Swerdlow, R.H.1    Khan, S.M.2
  • 83
    • 84856415487 scopus 로고    scopus 로고
    • The role of mitochondria in insulin resistance and type 2 diabetes mellitus
    • Szendroedi J, Phielix E, and Roden M (2012) The role of mitochondria in insulin resistance and type 2 diabetes mellitus. Nat Rev Endocrinol 8:92-103.
    • (2012) Nat Rev Endocrinol , vol.8 , pp. 92-103
    • Szendroedi, J.1    Phielix, E.2    Roden, M.3
  • 84
    • 0036194529 scopus 로고    scopus 로고
    • Mitochondria as a pharmacological target
    • DOI 10.1124/pr.54.1.101
    • Szewczyk A and Wojtczak L (2002) Mitochondria as a pharmacological target. Pharmacol Rev 54:101-127. (Pubitemid 34211027)
    • (2002) Pharmacological Reviews , vol.54 , Issue.1 , pp. 101-127
    • Szewczyk, A.1    Wojtczak, L.2
  • 85
    • 78649983748 scopus 로고    scopus 로고
    • Alzheimer's disease: Effects of β-amyloid on mitochondria
    • Tillement L, Lecanu L, and Papadopoulos V (2011) Alzheimer's disease: effects of β-amyloid on mitochondria. Mitochondrion 11:13-21.
    • (2011) Mitochondrion , vol.11 , pp. 13-21
    • Tillement, L.1    Lecanu, L.2    Papadopoulos, V.3
  • 86
    • 84856526180 scopus 로고    scopus 로고
    • The roles of phosphate and the phosphate carrier in the mitochondrial permeability transition pore
    • Varanyuwatana P and Halestrap AP (2012) The roles of phosphate and the phosphate carrier in the mitochondrial permeability transition pore. Mitochondrion 12:120-125.
    • (2012) Mitochondrion , vol.12 , pp. 120-125
    • Varanyuwatana, P.1    Halestrap, A.P.2
  • 87
    • 0033525773 scopus 로고    scopus 로고
    • Mitochondrial diseases in man and mouse
    • Wallace DC (1999) Mitochondrial diseases in man and mouse. Science 283:1482-1488.
    • (1999) Science , vol.283 , pp. 1482-1488
    • Wallace, D.C.1
  • 88
    • 23844558266 scopus 로고    scopus 로고
    • A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: A dawn for evolutionary medicine
    • Wallace DC (2005) A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine. Annu Rev Genet 39:359-407.
    • (2005) Annu Rev Genet , vol.39 , pp. 359-407
    • Wallace, D.C.1
  • 89
    • 70450231612 scopus 로고    scopus 로고
    • Energetics, epigenetics, mitochondrial genetics
    • Wallace DC and Fan W (2010) Energetics, epigenetics, mitochondrial genetics. Mitochondrion 10:12-31.
    • (2010) Mitochondrion , vol.10 , pp. 12-31
    • Wallace, D.C.1    Fan, W.2
  • 90
    • 73349091842 scopus 로고    scopus 로고
    • The role of mitochondria in apoptosis*
    • Wang C and Youle RJ (2009) The role of mitochondria in apoptosis*. Annu Rev Genet 43:95-118.
    • (2009) Annu Rev Genet , vol.43 , pp. 95-118
    • Wang, C.1    Youle, R.J.2
  • 91
    • 84862909353 scopus 로고    scopus 로고
    • The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways
    • Wang Z, Jiang H, Chen S, Du F, and Wang X (2012) The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways. Cell 148:228-243.
    • (2012) Cell , vol.148 , pp. 228-243
    • Wang, Z.1    Jiang, H.2    Chen, S.3    Du, F.4    Wang, X.5
  • 92
    • 84865175827 scopus 로고    scopus 로고
    • Historical perspectives on the discovery and development of drugs to treat neurological disorders
    • (Barrett JE, Coyle JT and Williams M eds) Cambridge University Press, Cambridge, UK
    • Williams M and Coyle JT (2012) Historical perspectives on the discovery and development of drugs to treat neurological disorders, in Translational Neuroscience Applications in Psychiatry, Neurology and Neurodevelopmental Disorders (Barrett JE, Coyle JT and Williams M eds) pp 129-148, Cambridge University Press, Cambridge, UK.
    • (2012) Translational Neuroscience Applications in Psychiatry, Neurology and Neurodevelopmental Disorders , pp. 129-148
    • Williams, M.1    Coyle, J.T.2
  • 93
    • 77955385260 scopus 로고    scopus 로고
    • Mitochondrial dysfunction: A potential link between neuroinflammation and neurodegeneration?
    • Witte ME, Geurts JJ, de Vries HE, van der Valk P, and van Horssen J (2010) Mitochondrial dysfunction: a potential link between neuroinflammation and neurodegeneration? Mitochondrion 10:411-418.
    • (2010) Mitochondrion , vol.10 , pp. 411-418
    • Witte, M.E.1    Geurts, J.J.2    De Vries, H.E.3    Van Der Valk, P.4    Van Horssen, J.5
  • 94
    • 79951548587 scopus 로고    scopus 로고
    • Inhibition of amyloid-β (Aβ) peptide-binding alcohol dehydrogenase-Aβ interaction reduces Aβ accumulation and improves mitochondrial function in a mouse model of Alzheimer's disease
    • Yao J, Du H, Yan S, Fang F, Wang C, Lue LF, Guo L, Chen D, Stern DM, Gunn Moore FJ, et al. (2011) Inhibition of amyloid-β (Aβ) peptide-binding alcohol dehydrogenase-Aβ interaction reduces Aβ accumulation and improves mitochondrial function in a mouse model of Alzheimer's disease. J Neurosci 31:2313-2320.
    • (2011) J Neurosci , vol.31 , pp. 2313-2320
    • Yao, J.1    Du, H.2    Yan, S.3    Fang, F.4    Wang, C.5    Lue, L.F.6    Guo, L.7    Chen, D.8    Stern, D.M.9    Gunn Moore, F.J.10
  • 96
    • 27644597606 scopus 로고    scopus 로고
    • Mitochondrial permeability transition in apoptosis and necrosis
    • DOI 10.1038/sj.cdd.4401682, PII 4401682
    • Zamzami N, Larochette N, and Kroemer G (2005) Mitochondrial permeability transition in apoptosis and necrosis. Cell Death Differ 12:1478-1480. (Pubitemid 41553982)
    • (2005) Cell Death and Differentiation , vol.12 , Issue.SUPPL. 2 , pp. 1478-1480
    • Zamzami, N.1    Larochette, N.2    Kroemer, G.3
  • 97
    • 77956214193 scopus 로고    scopus 로고
    • Dimebon (latrepirdine) enhances mitochondrial function and protects neuronal cells from death
    • Zhang S, Hedskog L, Petersen CA, Winblad B, and Ankarcrona M (2010) Dimebon (latrepirdine) enhances mitochondrial function and protects neuronal cells from death. J Alzheimers Dis 21:389-402.
    • (2010) J Alzheimers Dis , vol.21 , pp. 389-402
    • Zhang, S.1    Hedskog, L.2    Petersen, C.A.3    Winblad, B.4    Ankarcrona, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.