Pharmacological targeting of mitochondrial complex I deficiency: The cellular level and beyond

Mitochondrion

Volumn 12, Issue 1, 2012, Pages 57-65

  Roestenberg, Peggy ^a,b   Manjeri, Ganesh R ^a,b   Valsecchi, Federica ^a,b   Smeitink, Jan A M ^b   Willems, Peter H G M ^a   Koopman, Werner J H ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Calcium; CGP37165; Fibroblast; MitoQ; ROS; Trolox

Indexed keywords

7 CHLORO 5 (2 CHLOROPHENYL) 1,5 DIHYDRO 4,1 BENZOTHIAZEPIN 2(3H) ONE; ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; BEZAFIBRATE; CARNITINE; CELL NUCLEUS DNA; MITOCHONDRIAL DNA; MITOQUINONE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); RESVERATROL; RIBOFLAVIN; SZETO SCHILLER PEPTIDE; TRIPHENYL PHOSPHONIUM COMPOUND; TROLOX C; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; BIOGENESIS; DISEASE MODEL; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG MECHANISM; DRUG TARGETING; ELECTRON TRANSPORT; ENZYME DEFICIENCY; ENZYME DEGRADATION; ENZYME STABILITY; FIBROBLAST; GENE MUTATION; HUMAN; KETOGENIC DIET; MITOCHONDRIAL COMPLEX I DEFICIENCY; NONHUMAN; PRIORITY JOURNAL; REVIEW;

ANIMALS; DISEASE MODELS, ANIMAL; ELECTRON TRANSPORT COMPLEX I; HUMANS; MICE; MITOCHONDRIAL DISEASES;

EID: 84856547767     PISSN: 15677249     EISSN: 18728278     Source Type: Journal    
DOI: 10.1016/j.mito.2011.06.011     Document Type: Review

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