Bioenergetic effects of mitochondrial-targeted coenzyme Q analogs in endothelial cells

Journal of Pharmacology and Experimental Therapeutics

Volumn 342, Issue 3, 2012, Pages 709-719

  Fink, Brian D ^a,b   Herlein, Judith A ^a,b   Yorek, Mark A ^a,b   Fenner, Amanda M ^a   Kerns, Robert J ^a   Sivitz, William I ^a,b  

^a UNIVERSITY OF IOWA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ADENOSINE TRIPHOSPHATE; HYDROETHIDINE; HYDROGEN PEROXIDE; MANGANESE SUPEROXIDE DISMUTASE; MITOQUINOL; PLASTOQUINONYLDECYLTRIPHENYLPHOSPHONIUM; PORPHYRIN DERIVATIVE; SUPEROXIDE; TETRAKIS(1 METHYL 4 PYRIDYL)PORPHYRIN MANGANESE; UBIQUINONE DERIVATIVE; UNCLASSIFIED DRUG;

ACIDIFICATION; ANIMAL CELL; AORTA; ARTICLE; BIOENERGY; CONCENTRATION RESPONSE; CONTROLLED STUDY; COW; DRUG EFFECT; DRUG TARGETING; ENDOTHELIUM CELL; EXTRACELLULAR SPACE; GLYCOLYSIS; IC 50; MITOCHONDRION; NONHUMAN; OXIDATION REDUCTION REACTION; OXYGEN CONSUMPTION; PRIORITY JOURNAL;

ACETYLCYSTEINE; ADENOSINE TRIPHOSPHATE; ANIMALS; AORTA; CATTLE; CELL RESPIRATION; CELLS, CULTURED; ENDOTHELIAL CELLS; ENERGY METABOLISM; GLYCOLYSIS; HYDROGEN PEROXIDE; METALLOPORPHYRINS; MITOCHONDRIA; ONIUM COMPOUNDS; ORGANOPHOSPHORUS COMPOUNDS; OXIDATION-REDUCTION; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PLASTOQUINONE; PROTONS; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE; SUPEROXIDES; TRITYL COMPOUNDS; UBIQUINONE;

EID: 84864542395     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.112.195586     Document Type: Article

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