Involvement of Calpain/p35-p25/Cdk5/NMDAR signaling pathway in Glutamate-induced neurotoxicity in cultured rat retinal neurons

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Miao, Yanying ^a   Dong, Ling Dan ^a   Chen, Jie ^a   Hu, Xiao Chen ^a   Yang, Xiong Li ^a   Wang, Zhongfeng ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; CALPAIN; CALPAIN 2; CYCLIN DEPENDENT KINASE 5; DANTROLENE; FODRIN; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; PROTEIN P25; PROTEIN P35; ROSCOVITINE; XESTOSPONGIN C;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CELL CULTURE; CELL DAMAGE; CELL DEATH; CELL MEMBRANE; CELL VIABILITY; CONTROLLED STUDY; CYTOSOL; ENZYME REGULATION; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HIPPOCAMPUS; NEUROTOXICITY; NONHUMAN; PLEIOTROPY; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RAT; RETINA CELL; RETINA GANGLION CELL; RETINA NERVE CELL; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING;

ANIMALS; CALCIUM SIGNALING; CALPAIN; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE 5; GENE EXPRESSION REGULATION; GLUTAMIC ACID; NERVE TISSUE PROTEINS; PROTEOLYSIS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; RETINAL NEURONS; TIME FACTORS;

RATTUS;

EID: 84864780300     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0042318     Document Type: Article

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