Deletion of Tau attenuates heat shock-induced injury in cultured cortical neurons

Journal of Neuroscience Research

Volumn 88, Issue 1, 2010, Pages 102-110

  Yanying, Miao ^a   Jie, Chen ^a   Qipeng, Zhang ^a   Anyang, Sun ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Akt; Cortical neuron; Heat shock; HSP70; Tau

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3BETA; HEAT SHOCK PROTEIN 70; LACTATE DEHYDROGENASE; MICROTUBULE ASSOCIATED PROTEIN 2; PROTEIN KINASE B; TAU PROTEIN; TUBULIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN CELL; CELL CULTURE; CELL DAMAGE; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; EXPOSURE; HEAT SHOCK; KNOCKOUT GENE; MORBIDITY; MOUSE; NERVE CELL LESION; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; STAINING; STIMULUS; STRESS; WILD TYPE;

ANALYSIS OF VARIANCE; ANIMALS; BLOTTING, WESTERN; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; FLUORESCENT ANTIBODY TECHNIQUE; GLYCOGEN SYNTHASE KINASE 3; HEAT-SHOCK RESPONSE; HOT TEMPERATURE; MICE; MICE, KNOCKOUT; NEURONS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; TAU PROTEINS; TIME FACTORS;

EID: 73949100672     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.22188     Document Type: Article

References (35)

1. Barber AJ, Nakamura M, Wolpert EB, Reiter CE, Seigel GM, Antonetti DA, Gardner TW. 2001. Insulin rescues retinal neurons from apoptosis by a phosphatidylinositol 3-kinase/Akt-mediated mechanism that reduces the activation of caspase-3. J Biol Chem 276:32814-32821.
2. Brewer GJ. 1995. Serum-free B27/neurobasal medium supports differentiated growth of neurons from the striatum, substantia nigra, septum, cerebral cortex, cerebellum, and dentate gyrus. J Neurosci Res 42:674-683.
3. Dawson HN, Ferreira A, Eyster MV, Ghoshal N, Binder LI, Vitek MP. 2001. Inhibition of neuronal maturation in primary hippocampal neurons from tau deficient mice. J Cell Sci 114:1179-1187.
4. Dickey CA, Kamal A, Lundgren K, Klosak N, Bailey RM, Dunmore J, Ash P, Shoraka S, Zlatkovic J, Eckman CB, Patterson C, Dickson DW, Nahman NS Jr, Hutton M, Burrows F, Petrucelli L. 2007. The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins. J Clin Invest 117:648-658.
5. Dickey CA, Koren J, Zhang YJ, Xu YF, Jinwal UK, Birnbaum MJ, Monks B, Sun M, Cheng JQ, Patterson C, Bailey RM, Dunmore J, Soresh S, Leon C, Morgan D, Petrucelli L. 2008. Akt and CHIP coregulate tau degradation through coordinated interactions. Proc Natl Acad Sci U S A 105:3622-3627.
6. Dou F, Netzer WJ, Tanemura K, Li F, Hartl FU, Takashima A, Gouras GK, Greengard P, Xu H. 2003. Chaperones increase association of tau protein with microtubules. Proc Natl Acad Sci USA 100:721-726.
7. Duff K, Planel E. 2005. Untangling memory deficits. Nat Med 11:826-827.
8. Fath T, Eidenmü ller J, Brandt R. 2002. Tau-mediated cytotoxicity in a pseudohyperphosphorylation model of Alzheimer's disease. J Neurosci 22:9733-9741.
9. Gordon D, Kidd GJ, Smith R. 2008. Antisense suppression of tau in cultured rat oligodendrocytes inhibits process formation. J Neurosci Res 86:2591-2601.
10. Hamos JE, Oblas B, Pulaski-Salo D, Welch WJ, Bole DG, Drachman DA. 1991. Expression of heat shock proteins in Alzheimer's disease. Neurology 41:345-350.
11. Harada A, Oguchi K, Okabe S, Kuno J, Terada S, Ohshima T, Sato-Yoshitake R, Takei Y, Noda T, Hirokawa N. 1994. Altered microtubule organization in small-calibre axons of mice lacking tau protein. Nature 369:488-491.
12. Horowitz M, Robinson SD. 2007. Heat shock proteins and the heat shock response during hyperthermia and its modulation by altered physiological conditions. Prog Brain Res 162:433-446.
13. Hunt S, Pini A andEvan G. 1987. Induction of c-fos-like protein in spinal cord neurons following sensory stimulation. Nature 328:632-534.
14. Hutton M, Lendon CL, Rizzu P, Baker M, Froelich S, Houlden H, Pickering-Brown S, Heutink P. 1998. Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17. Nature 393:702-705.
15. Ksiezak-Reding H, Pyo HK, Feinstein B, Pasinetti GM. 2003. Akt/PKB kinase phosphorylates separately Thr212 and Ser214 of tau protein in vitro. Biochim Biophys Acta 1639:159-168.
16. Lee VM, Balin BJ, Otvos L Jr, Trojanowski JQ. 1991. A68: a major subunit of paired helical filaments and derivatized forms of normal Tau. Science 251:675-678.
17. Lesort M, Blanchard C, Yardin C, Esclaire F, Hugon J. 1997. Cultured neurons expressing phosphorylated tau are more resistant to apoptosis induced by NMDA or serum deprivation. Brain Res Mol Brain Res 45:127-132.
18. Mandelkow EM, Biernat J, Drewes G, Gustke N, Trinczek B, Mandelkow E. 1995. Tau domains, phosphorylation, and interactions with microtubules. Neurobiol Aging 16:355-362.
19. Mercado-Gómez O, Hernández-Fonseca K, Villavicencio- Queijeiro A, Massieu L, Chimal-Monroy J, Arias C. 2008. Inhibition of Wnt and PI3K signaling modulates GSK-3β activity and induces morphological changes in cortical neurons: role of tau phosphorylation. Neurochem Res 33:1599-1609.
20. Oyama F, Kotliarova S, Harada A, Ito M, Miyazaki H, Ueyama Y, Hirokawa N, Nukina N, Ihara Y. 2004. Gem GTPase and tau: morphological changes induced by gem GTPase in cho cells are antagonized by tau. J Biol Chem 279:27272-27277.
21. Papasozomenos SC, Su Y. 1991. Altered phosphorylation of tau protein in heat-shocked rats and patients with Alzheimer disease. Proc Natl Acad Sci U S A 88:4543-4547.
22. Pizzi M, Valerio A, Arrighi V, Galli P, Belloni M, Ribola M, Alberici A, Spano P, Memo M. 1995. Inhibition of glutamate-induced neurotoxicity by a tau antisense oligonucleotide in primary culture of rat cerebellar granule cells. Eur J Neurosci 7:1603-1613.
23. Rapoport M, Dawson HN, Binder LI, Vitek MP, Ferreira A. 2002. Tau is essential to β-amyloid-induced neurotoxicity. Proc Natl Acad Sci USA 99:6364-6369.
24. Reynolds CH, Garwood CJ, Wray S, Price C, Kellie S, Perera T, Zvelebil M, Yang A, Sheppard PW, Varndell IM, Hanger DP, Anderton BH. 2008. Phosphorylation regulates tau interactions with Src homology 3 domains of phosphatidylinositol 3-kinase, phospholipase Cgamma1, Grb2, and Src family kinases. J Biol Chem 283:18177-18186.
25. Roberson ED, Scearce-Levie K, Palop JJ, Yan F, Cheng IH, Wu T, Gerstein H, Yu GQ, Mucke L. 2007. Reducing endogenous tau ameliorates amyloid β-induced deficits in an Alzheimer's disease mouse model. Science 316:750-754.
26. Ryder J, Su Y, Ni B. 2004. Akt/GSK3b serine/threonine kinases: evidence for a signalling pathway mediated by familial Alzheimer's disease mutations. Cell Signal 16:187-200.
27. Sahara N, Murayama M, Mizoroki T, Urushitani M, Imai Y, Takahashi R, Murata S, Tanaka K, Takashima A. 2005. In vivo evidence of CHIP up-regulation attenuating tau aggregation. J Neurochem 94:1254-1263.
28. Sahara N, Maeda S, Yoshiike Y, Mizoroki T, Yamashita S, Murayama M, Park JM, Saito Y, Murayama S, Takashima A. 2007. Molecular chaperone-mediated tau protein metabolism counteracts the formation of granular tau oligomers in human brain. J Neurosci Res 85:3098-3108.
29. Santacruz K, Lewis J, Spires T, Paulson J, Kotilinek L, Ingelsson M, Guimaraes A, DeTure M, Ramsden M, McGowan E, Forster C, Yue M, Orne J, Janus C, Mariash A, Kuskowski M, Hyman B, Hutton M, Ashe KH. 2005. Tau suppression in a neurodegenerative mouse model improves memory function. Science 309:476-481.
30. Shamovsky I, Nudler E. 2008. New insights into the mechanism of heat shock response activation. Cell Mol Life Sci 65:855-861.
31. Shimura H, Miura-Shimura Y, Kosik KS. 2004. Binding of tau to heat shock protein 27 leads to decreased concentration of hyperphosphorylated tau and enhanced cell survival. J Biol Chem 279:17957-17962.
32. Shinohara T, Takahashi N, Ooie T, Hara M, Shigematsu S, Nakagawa M, Yonemochi H, Saikawa T, Yoshimatsu H. 2006. Phosphatidylinositol 3-kinase-dependent activation of akt, an essential signal for hyperthermia-induced heat-shock protein 72, is attenuated in streptozotocin-induced diabetic heart. Diabetes 55:1307-1315.
33. Trnecková L, Rotllant D, Klenerová V, Hynie S, Armario A. 2007. Dynamics of immediate early gene and neuropeptide gene response to prolonged immobilization stress: evidence against a critical role of the termination of exposure to the stressor. J Neurochem 100:905-914.
34. Wang JZ, Liu F. 2008. Microtubule-associated protein tau in development, degeneration and protection of neurons. Prog Neurobiol 85:148-175.
35. Yoo BC, Seidl R, Cairns N, Lubec G. 1999. Heat-shock protein 70 levels in brain of patients with Down syndrome and Alzheimer's disease. J Neural Transm Suppl 57:315-322.