Cyclin-Dependent Kinase 5 Phosphorylates the N-Terminal Domain of the Postsynaptic Density Protein PSD-95 in Neurons

Journal of Neuroscience

Volumn 24, Issue 4, 2004, Pages 865-876

  Morabito, Maria A ^a,c   Sheng, Morgan ^b   Tsai, Li Huei ^b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Cdk5; NMDA receptor clustering; Phosphorylation; PSD 95; PSD 95 multimerization; Synapse

Indexed keywords

CYCLIN DEPENDENT KINASE 5; DOPAMINE; ION CHANNEL; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; POSTSYNAPTIC DENSITY PROTEIN 95; PROLINE DIRECTED PROTEIN KINASE; PROTEIN P35;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN CELL; BRAIN DEVELOPMENT; COCAINE DEPENDENCE; CONTROLLED STUDY; CYTOSKELETON; DEGENERATIVE DISEASE; EMBRYO; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NERVE CELL; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN POLYMERIZATION; PROTEIN TARGETING; RAT; RECEPTOR DENSITY; SIGNAL TRANSDUCTION; SYNAPSE;

ANIMALS; COS CELLS; CYCLIN-DEPENDENT KINASE 5; CYCLIN-DEPENDENT KINASES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; ION CHANNELS; MACROMOLECULAR SUBSTANCES; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; MUTAGENESIS, SITE-DIRECTED; NERVE TISSUE PROTEINS; NEURONAL PLASTICITY; NEURONS; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; SYNAPSES;

EID: 0742270492     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4582-03.2004     Document Type: Article

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