Melatonin potentiates glycine currents through a PLC/PKC signalling pathway in rat retinal ganglion cells

Journal of Physiology

Volumn 588, Issue 14, 2010, Pages 2605-2619

  Zhao, Wen Jie ^a   Zhang, Min ^a   Miao, Yanying ^a   Yang, Xiong Li ^a   Wang, Zhongfeng ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 4 P PDOT; 8 BROMO CYCLIC AMP; 8 BROMO CYCLIC GMP; BISINDOLYLMALEIMIDE; BISINDOLYLMALEIMIDE IV; CALCIUM; CHELATE; CYCLIC AMP; CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; FLUORESCENT DYE; GI GO MELATONIN 2 RECEPTOR; GLYCINE; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE DIPHOSPHATE; GUANOSINE DIPHOSPHATE BETA S; HORMONE RECEPTOR BLOCKING AGENT; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; KT 5823; MELATONIN; MELATONIN 2 RECEPTOR; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PERTUSSIS TOXIN; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHOLIPASE C; PROTEIN KINASE C; TRICYCLO[4.3.0.1]DECAN 9 YL XANTHOGENATE; UNCLASSIFIED DRUG; 1,2-BIS(2-AMINOPHENOXY)ETHANE-N,N,N',N'-TETRAACETIC ACID; 1-(6-((3-METHOXYESTRA-1,3,5(10)-TRIEN-17-YL)AMINO)HEXYL)-1H-PYRROLE-2,5-DIONE; 2 PYRROLIDONE DERIVATIVE; 4-PHENYL-2-PROPIONAMIDOTETRALINE; 8-BROMOCYCLIC GMP; BRIDGED COMPOUND; CARBAZOLE DERIVATIVE; EGTAZIC ACID; ESTRANE DERIVATIVE; INDOLE DERIVATIVE; ISOQUINOLINE DERIVATIVE; MALEIMIDE DERIVATIVE; N-(2-(4-BROMOCINNAMYLAMINO)ETHYL)-5-ISOQUINOLINESULFONAMIDE; SULFONAMIDE; TETRALIN DERIVATIVE; THIOKETONE; TRICYCLODECANE-9-YL-XANTHOGENATE; GLYCINE RECEPTOR; PHOSPHATIDYLCHOLINE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DIALYSIS; EVOKED RESPONSE; IMMUNOFLUORESCENCE; IMMUNOREACTIVITY; INHIBITORY POSTSYNAPTIC POTENTIAL; ION CURRENT; LIGHT; LONG TERM POTENTIATION; MALE; NIGHT; NIGHT VISION; NONHUMAN; POSTSYNAPTIC POTENTIAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RETINA AMACRINE CELL; RETINA GANGLION CELL; SIGNAL TRANSDUCTION; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; ENZYMOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT; ANIMAL TISSUE; CALCIUM CELL LEVEL; CALCIUM CHELATION; CELL LABELING; CHELATION; DARK ADAPTATION; ENZYME ACTIVATION; GLYCINE CURRENT; IMMUNOCYTOCHEMISTRY; IMMUNOFLUORESCENCE TEST; INTRACELLULAR DIALYSIS; INTRACELLULAR SIGNALING; MOLECULAR DYNAMICS; TRANSPORT KINETICS;

8-BROMO CYCLIC ADENOSINE MONOPHOSPHATE; ANIMALS; BRIDGED COMPOUNDS; CALCIUM; CARBAZOLES; CYCLIC GMP; CYCLIC GMP-DEPENDENT PROTEIN KINASES; EGTAZIC ACID; ESTRENES; GLYCINE; GUANOSINE DIPHOSPHATE; INDOLES; ISOQUINOLINES; MALE; MALEIMIDES; MELATONIN; PERTUSSIS TOXIN; PROTEIN KINASE C; PYRROLIDINONES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, MELATONIN, MT2; RETINAL GANGLION CELLS; SIGNAL TRANSDUCTION; SULFONAMIDES; TETRADECANOYLPHORBOL ACETATE; TETRAHYDRONAPHTHALENES; THIONES; TYPE C PHOSPHOLIPASES;

EID: 77954721956     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2010.187641     Document Type: Article

References (62)

1. Alarma-Estrany P, Pintor J. Melatonin receptors in the eye: location, second messengers and role in ocular physiology. Pharmacol Ther 2007, 113:507-522.
2. Barrenetxe J, Delagrange P, Martinez JA. Physiological and metabolic functions of melatonin. J Physiol Biochem 2004, 60:61-72.
3. Bers DM, Patton CW, Nuccitelli R. A practical guide to the preparation of Ca2+ buffers. Methods Cell Biol 1994, 40:3-29.
4. Cahill GM, Besharse JC. Light-sensitive melatonin synthesis by Xenopus photoreceptors after destruction of the inner retina. Vis Neurosci 1992, 8:487-490.
5. Cecchetti S, Spadaro F, Lugini L, Podo F, Ramoni C. Functional role of phosphatidycholine-specific phospholipases C in regulating CD16 membrane expression in natural killer cells. Eur J Immunol 2007, 37:2912-2922.
6. Chen L, Yu YC, Zhao JW, Yang XL. Inwardly rectifying potassium channels in rat retinal ganglion cells. Eur J Neurosci 2004, 20:956-964.
7. Drummond GB. Reporting ethical matters in The Journal of Physiology: standards and advice. J Physiol 2009, 587:713-719.
8. Dubocovich ML, Hudson RL, Sumaya IC, Masana MI, Manna E. Effect of MT1 melatonin receptor deletion on melatonin-mediated phase shift of circadian rhythms in the C57BL/6 mouse. J Pineal Res 2005, 39:113-120.
9. Dubocovich ML, Rivera-Bermúdez MA, Gerdin MJ, Masana MI. Molecular pharmacology, regulation and function of mammalian melatonin receptors. Front Biosci 2003, 8:d1093-1108.
10. Fujieda H, Hamadanizadeh SA, Wankiewicz E, Pang SF, Brown GM. Expression of mt1 melatonin receptor in rat retina: evidence for multiple cell targets for melatonin. Neuroscience 1999, 93:793-799.
11. Gerdin MJ, Masana MI, Rivera-Bermúdez MA, Hudson RL, Earnest DJ, Gillette MU, Dubocovich ML. Melatonin desensitizes endogenous MT2 melatonin receptors in the rat suprachiasmatic nucleus: relevance for defining the periods of sensitivity of the mammalian circadian clock to melatonin. FASEB J 2004, 18:1646-1656.
12. Girón-Calle J, Srivatsa K, Forman HJ. Priming of alveolar macrophage respiratory burst by H2O2 is prevented by phosphatidylcholine-specific phospholipase C inhibitor tricyclodecan-9-yl-xanthate (D609). J Pharmacol Exp Ther 2002, 301:87-94.
13. Gu Y, Huang LY. Cross-modulation of glycine-activated Cl- channels by protein kinase C and cAMP-dependent protein kinase in the rat. J Physiol 1998, 506:331-339.
14. Han Y, Slaughter MM. Protein kinases modulate two glycine currents in salamander retinal ganglion cells. J Physiol 1998, 508:681-690.
15. Hirsch JA. Synaptic physiology and receptive field structure in the early visual pathway of the cat. Cerebral Cortex 2003, 13:63-69.
16. Hsueh HA, Molnar A, Werblin FS. Amacrine-to-amacrine cell inhibition in the rabbit retina. J Neurophysiol 2008, 100:2077-2088.
17. Huang H, Lee SC, Yang XL. Modulation by melatonin of glutamatergic synaptic transmission in the carp retina. J Physiol 2005, 569:857-871.
18. Kang MS, Jung SY, Jung KM, Kim SK, Ahn KH, Kim DK. D609, an inhibitor of phosphatidylcholine-specific phospholipase C, inhibits group IV cytosolic phospholipase A2. Mol Cells 2008, 30:481-485.
19. Lai FP, Mody SM, Yung LY, Kam JY, Pang CS, Pang SF, Wong YH. Molecular determinants for the differential coupling of Gα16 to the melatonin MT1, MT2 and Xenopus Mel1c receptors. J Neurochem 2002, 80:736-745.
20. Lai FP, Mody SM, Yung LY, Pang CS, Pang SF, Wong YH. Chimeric Gαq subunits can distinguish the long form of the Xenopus Mel1c melatonin receptor from the mammalian mt1 and MT2 melatonin receptors. J Pineal Res 2001, 30:171-179.
21. MacKenzie RS, Melan MA, Passey DK, Witt-Enderby PA. Dual coupling of MT1 and MT2 melatonin receptors to cyclic AMP and phosphoinositide signal transduction cascades and their regulation following melatonin exposure. Biochem Pharmacol 2002, 63:587-595.
22. Manookin MB, Beaudoin DL, Ernst ZR, Flagel LJ, Demb JB. Disinhibition combines with excitation to extend the operating range of the OFF visual pathway in daylight. J Neurosci 2008, 28:4136-4150.
23. Masana MI, Dubocovich ML. Melatonin receptors signalling: finding the path through the dark. Sci STKE 2001, 107:pe39.
24. Mateas MV, Uranga RM, Salvador GA, Giusto NM. Coexistence of phosphatidycholine-specific phospholipases C and phospholipase D activities in rat cerebral cortex synaptosomes. Lipids 2006, 41:273-280.
25. McArthur AJ, Hunt AE, Gillette MU. Melatonin action and signal transduction in the rat suprachiasmatic circadian clock: activation of protein kinase C at dusk and dawn. Endocrinology 1997, 138:627-634.
26. Menger N, Pow DV, Wässle H. Glycinergic amacrine cells of the rat retina. J Comp Neurol 1998, 401:34-46.
27. Molnar A, Hsueh HA, Roska B, Werbin FS. Crossover inhibition in the retina: circuitry that compensates for nonlinear rectifying synaptic transmission. J Comput Neurosci 2009, 27:569-590.
28. Müller F, Wässle H, Voigt T. Pharmacological modulation of the rod pathway in the cat retina. J Neurophysiol 1988, 59:1657-1672.
29. Murphy GJ, Rieke F. Signals and noise in an inhibitory interneuron diverge to control activity in nearby retinal ganglion cells. Nat Neurosci 2008, 11:318-326.
30. Natesan AK, Cassone VM. Melatonin receptor mRNA localization and rhythmicity in the retina of the domestic chick, Gallus domesticus. Vis Neurosci 2002, 19:265-274.
31. Nishizaki T, Ikeuchi Y. Activation of endogenous protein kinase C enhances currents through α1 and α2 glycine receptor channels. Brain Res 1995, 687:214-216.
32. Petit L, Lacroix I, de Coppet P, Strosberg AD, Jockers R. Differential signalling of human Mel1a and Mel1b melatonin receptors through the cyclic guanosine 3′-5′-monophosphate pathway. Biochem Pharmacol 1999, 58:633-639.
33. Ping Y, Huang H, Zhang XJ, Yang XL. Melatonin potentiates rod signals to ON type bipolar cell in fish retina. J Physiol 2008, 586:2683-2694.
34. Protti DA, Gerschenfeld HM, Llano I. GABAergic and glycinergic IPSCs in ganglion cells of rat retinal slices. J Neurosci 1997, 17:6075-6085.
35. Ramoni C, Spadaro F, Menegon M, Podo F. Cellular localization and functional role of phosphatidycholine-specific phospholipases C in NK cells. J Immunol 2001, 167:2642-2650.
36. Ren J, Ye JH, McArdle JJ. cAMP-dependent protein kinase modulation of glycine-activated chloride current in neurons freshly isolated from rat ventral tegmental area. Brain Res 1998, 811:71-78.
37. Reppert SM, Godson C, Mahle CD, Weaver DR, Slaugenhaupt SA, Gusella JF. Molecular charaterization of a second melatonin receptor expressed in human retina and brain: the Mel1b melatonin receptor. Proc Natl Acad Sci U S A 1995, 92:8734-8738.
38. Reppert SM, Weaver DR, Ebisawa T. Cloning and characterization of a mammalian melatonin receptor that mediates reproductive and circadian responses. Neuron 1994, 13:1177-1185.
39. Ribelayga C, Wang Y, Mangel SC. A circadian clock in the fish retina regulates dopamine release via activation of melatonin receptors. J Physiol 2004, 554:467-482.
40. Roka F, Brydon L, Waldhoer M, Strosberg AD, Freissmuth M, Jockers R, Nanoff C. Tight association of the human Mel1a-melatonin receptor and Gi: precoupling and constitutive activity. Mol Pharmacol 1999, 56:1014-1124.
41. Roska B, Molnar A, Werblin FS. Parallel processing in retinal ganglion cells: how integration of space-time patterns of excitation and inhibition form the spiking output. J Neurophysiol 2006, 95:3810-3822.
42. Ross AW, Webster CA, Thompson M, Barrett P, Morgan PJ. A novel interaction between inhibitory melatonin receptors and protein kinase C-dependent signal transduction in ovine pars tuberalis cells. Endocrinology 1998, 139:1723-1730.
43. Ruiz-Gómez A, Vaello ML, Valdivieso F, Mayor F. Phosphorylation of the 48-kDa subunit of the glycine receptor by protein kinase C. J Biol Chem 1991, 266:559-566.
44. Savaskan E, Wirz-Justice A, Olivieri G, Pache M, Krauchi K, Brydon L, Jockers R, Müller-Spahn F, Meyer P. Distribution of melatonin MT1 receptor immunoreactivity in human retina. J Histochem Cytochem 2002, 50:519-526.
45. Slaughter MM. Inhibition in the retina. The Visual Neurosciences 2004, vol 1:355-368. Chalupa LMWerner JS. In, ed, pp, MIT Press, Cambridge, MA, USA
46. Spadaro F, Cecchetti S, Sanchez M, Ausiello CM, Podo F, Ramoni C. Expression and role of phosphatidycholine-specific phospholipases C in human NK and T-lymphocyte subsets. Eur J Immunol 2006, 36:3277-3287.
47. Spadaro F, Ramoni C, Mezzanzanica D, Miotti S, Alberti P, Cecchetti S, Iorio E, Dolo V, Canevari S, Podo F. Phosphatidycholine-specific phospholipases C activity in epithelial ovarian cancer cells. Cancer Res 2008, 68:6541-6549.
48. Tapia JC, Espinoza F, Aguayo LG. Differential intracellular regulation of cortical GABAA and spinal glycine receptors in cultured neurons. Brain Res 1997, 769:203-210.
49. Tosini G, Fukuhara C. Photic and circadian regulation of retinal melatonin in mammals. J Neuroendocrinol 2003, 15:364-369.
50. Tzeng JI, Chen BC, Chang HM, Wang JJ, Sureshbabu M, Chien MH, Hsu MJ, Bien MY, Chiu WT, Hong CY, Lin CH. Involvement of phosphatidycholine-phospholipase C and protein kinase C in peptidolycan-induced nuclear factor-κB activation and cyclooxygenase-2 expression in RAW 264.7 macrophages. Pharmacol Res 2010, 61:162-166.
51. Vaello ML, Ruiz-Gómez A, Lerma J, Mayor F. Modulation of inhibitory glycine receptors by phosphorylation by protein kinase C and cAMP-dependent protein kinase. J Biol Chem 1994, 269:2002-2008.
52. Vanecek J. Cellular mechanisms of melatonin action. Physiol Rev 1998, 78:687-721.
53. Van Wyk M, Wässle H, Taylor WR. Receptive field properties of ON- and OFF-ganglion cells in the mouse retina. Vis Neurosci 2009, 26:297-308.
54. Wässle H. Parallel processing in the mammalian retina. Nat Rev Neurosci 2004, 5:1-11.
55. Wässle H, Heinze L, Ivanova E, Majumdar S, Weiss J, Harvey RJ, Haverkamp S. Glycinergic transmission in the mammalian retina. Front Mol Neurosci 2009, 2:1-12.
56. Way KJ, Chou E, King GL. Identification of PKC-isoform-specific biological actions using pharmacological approaches. Trends Pharmacol Sci 2000, 21:181-187.
57. Weernink PAO, Han L, Jakobs KH, Schmidt M. Dynamic phospholipids signalling by G protein-coupled receptors. Biochim Biophys Acta 2007, 1768:888-900.
58. Wiechmann AF. Differential distribution of Mel1a and Mel1c melatonin receptors in Xenopus laevis retina. Exp Eye Res 2003, 76:99-106.
59. Wiechmann AF, Udin SB, Summers Rada JA. Localization of Mel1b melatonin receptor-like immunoreactivity in ocular tissues of Xenopus laevis. Exp Eye Res 2004, 79:585-594.
60. Yu YC, Cao LH, Yang XL. Modulation by brain natriuretic peptide of GABA receptors on rat retinal ON-type bipolar cells. J Neurosci 2006, 26:696-707.
61. Zhang M, Cao LH, Yang XL. Melatonin modulates glycine currents of retinal ganglion cells in rat. Neuroreport 2007, 18:1675-1678.
62. Zaghloul KA, Boahen K, Demb JB. Different circuits for ON and OFF retinal ganglion cells cause different contrast sensitivities. J Neurosci 2003, 23:2645-2654.