Calpain activation in experimental glaucoma

Investigative Ophthalmology and Visual Science

Volumn 51, Issue 6, 2010, Pages 3049-3054

  Huang, Wei ^a   Fileta, John ^a   Rawe, Ian ^b   Qu, Juan ^a   Grosskreutz, Cynthia L ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b SCHEPENS EYE RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCINEURIN; CALPAIN; SPECTRIN;

ADULT ANIMAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME LOCALIZATION; GLAUCOMA; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; INTRAOCULAR PRESSURE; MALE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEOMICS; RAT; RETINA; ANIMAL; BROWN NORWAY RAT; CALCINOSIS; DISEASE MODEL; ENZYME IMMUNOASSAY; ENZYMOLOGY; MASS SPECTROMETRY; METABOLISM; PATHOLOGY; RETINA GANGLION CELL; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CALCINOSIS; CALPAIN; DISEASE MODELS, ANIMAL; ENZYME ACTIVATION; GLAUCOMA; IMMUNOENZYME TECHNIQUES; IMMUNOPRECIPITATION; INTRAOCULAR PRESSURE; MALE; PROTEOMICS; RATS; RATS, INBRED BN; RETINAL GANGLION CELLS; SPECTRIN; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 77953240485     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.09-4364     Document Type: Article

References (36)

1. Quigley HA. Number of people with glaucoma worldwide. Br J Ophthalmol. 1996;80(5):389-393
2. Leske MC, Heijl A, Hussein M, Bengtsson B, Hyman L, Komaroff E. Factors for glaucoma progression and the effect of treatment: the early manifest glaucoma trial. Arch Ophthalmol 2003;121(1):48-56.
3. Hanninen VA, Pantcheva MB, Freeman EE, Poulin NR, Grosskreutz CL. Activation of caspase 9 in a rat model of experimental glaucoma. Curr Eye Res. 2002;25(6):389-395
4. Huang W, Dobberfuhl A, Filippopoulos T, et al. Transcriptional upregulation and activation of initiating caspases in experimental glaucoma. Am J Pathol. 2005;167(3):673-681.
5. McKinnon SJ, Lehman DM, Kerrigan-Baumrind LA, et al. Caspase activation and amyloid precursor protein cleavage in rat ocular hypertension. Invest Ophthalmol Vis Sci. 2002;43(4):1077-1087.
6. Wax MB, Tezel G, Edward PD. Clinical and ocular histopathologi-cal findings in a patient with normal-pressure glaucoma [see comments]. Arch Ophthalmol. 1998;116(8):993-1001.
7. Azuma M, Shearer TR. The role of calcium-activated protease calpain in experimental retinal pathology. Surv Ophthalmol. 2008; 53(2):150-163.
8. Osborne NN, Cazevieille C, Carvalho AL, Larsen AK, DeSantis L. In vivo and in vitro experiments show that betaxolol is a retinal neuroprotective agent. Brain Res. 1997;751(1):113-123.
9. Osborne NN, Ugarte M, Chao M, et al. Neuroprotection in relation to retinal ischemia and relevance to glaucoma. Surv Ophthalmol. 1999;43(suppl 1):S102-S128.
10. Sappington RM, Sidorova T, Long DJ, Calkins DJ. TRPV1: contribution to retinal ganglion cell apoptosis and increased intracellular Ca2+ with exposure to hydrostatic pressure. Invest Ophthalmol Vis Sci. 2009;50(2):717-728.
11. Wojda U, Salinska E, Kuznicki J. Calcium ions in neuronal degeneration. IUBMB Life. 2008;60(9):575-590.
12. Huang W, Fileta J, Dobberfuhl A, et al. Calcineurin cleavage is triggered by elevated intraocular pressure and calcineurin inhibition blocks retinal ganglion cell death in experimental glaucoma. Proc Natl Acad Sci USA. 2005;102(34):12242-12247.
13. Goll DE, Thompson VF, Li H, Wei W, Cong J. The calpain system. Physiol Rev. 2003;83(3):731-801.
14. Cottin P, Thompson VF, Sathe SK, Szpacenko A, Goll DE. Autolysis of mu- and m-calpain from bovine skeletal muscle. Biol Chem. 2001;382(5):767-776.
15. Nath R, Raser KJ, Stafford D, et al. Non-erythroid alpha-spectrin breakdown by calpain and interleukin 1 beta-converting-enzymelike protease (s) in apoptotic cells: contributory roles of both protease families in neuronal apoptosis. Biochem J. 1996;319(pt 3):683-690.
16. Nixon RA. The calpains in aging and aging-related diseases. Ageing Res Rev. 2003;2(4):407-418.
17. Sakamoto YR, Nakajima TR, Fukiage CR, et al. Involvement of calpain isoforms in ischemia-reperfusion injury in rat retina. Curr Eye Res. 2000;21(1):571-580.
18. McKernan DP, Guerin MB, O'Brien CJ, Cotter TG. A key role for calpains in retinal ganglion cell death. Invest Ophthalmol Vis Sci. 2007;48(12):5420-5430.
19. Sanvicens N, Cotter TG. Ceramide is the key mediator of oxidative stress-induced apoptosis in retinal photoreceptor cells. J Neuro-chem. 2006;98(5):1432-1444.
20. Chiu K, Lam TT, Ying Li WW, Caprioli J, Kwong Kwong JM. Calpain and N-methyl-D-aspartate (NMDA)-induced excitotoxicity in rat retinas. Brain Res. 2005;1046(1-2):207-215.
21. Volbracht C, Chua BT, Ng CP, Bahr BA, Hong W, Li P. The critical role of calpain versus caspase activation in excitotoxic injury induced by nitric oxide. J Neurochem. 2005;93(5):1280-1292.
22. Wu HY, Tomizawa K, Oda Y, et al. Critical role of calpain-mediated cleavage of calcineurin in excitotoxic neurodegeneration. J Biol Chem. 2004;279(6):4929-4940.
23. Shioda N, Moriguchi S, Shirasaki Y, Fukunaga K. Generation of constitutively active calcineurin by calpain contributes to delayed neuronal death following mouse brain ischemia. J Neurochem. 2006;98(1):310-320.
24. Mukerjee N, McGinnis KM, Park YH, Gnegy ME, Wang KK. Caspase-mediated proteolytic activation of calcineurin in thapsi-gargin-mediated apoptosis in SH-SY5Y neuroblastoma cells. Arch Biochem Biophys. 2000;379(2):337-343.
25. Morrison JC, Moore CG, Deppmeier LM, Gold BG, Meshul CK, Johnson EC. A rat model of chronic pressure-induced optic nerve damage. Exp Eye Res. 1997;64(1):85-96.
26. Tompa P, Buzder-Lantos P, Tantos A, et al. On the sequential determinants of calpain cleavage. J Biol Chem. 2004;279(20): 20775-20785.
27. Burkard N, Becher J, Heindl C, Neyses L, Schuh K, Ritter O. Targeted proteolysis sustains calcineurin activation. Circulation. 2005;111(8):1045-1053.
28. Oka T, Tamada Y, Nakajima E, Shearer TR, Azuma M. Presence of calpain-induced proteolysis in retinal degeneration and dysfunction in a rat model of acute ocular hypertension. J Neurosci Res. 2006;83(7):1342-1351.
29. Oka T, Walkup RD, Tamada Y, et al. Amelioration of retinal degeneration and proteolysis in acute ocular hypertensive rats by calpain inhibitor ((1S)-1-((((1S)-1-benzyl-3-cyclopropylamino-2,3-di-oxopropyl)amino)carbony l)-3-methylbutyl)carbamic acid 5-me-thoxy-3-oxapentyl ester. Neuroscience. 2006;141(4):2139-2145.
30. Tahzib NG, Ransom NL, Reitsamer HA, McKinnon SJ. Alpha-fodrin is cleaved by caspase-3 in a chronic ocular hypertensive (COH) rat model of glaucoma. Brain Res Bull. 2004;62(6):491-495.
31. Saatman KE, Abai B, Grosvenor A, Vorwerk CK, Smith DH, Meaney DF. Traumatic axonal injury results in biphasic calpain activation and retrograde transport impairment in mice. J Cereb Blood Flow Metab. 2003;23(1):34-42.
32. Sanders EJ, Parker E, Harvey S. Retinal ganglion cell survival in development: mechanisms of retinal growth hormone action. Exp Eye Res. 2006;83(5):1205-1214.
33. Blomgren K, Zhu C, Wang X, et al. Synergistic activation of caspase-3 by m-calpain after neonatal hypoxia-ischemia: a mechanism of "pathological apoptosis"? J Biol Chem. 2001;276(13): 10191-10198.
34. Porn-Ares MI, Samali A, Orrenius S. Cleavage of the calpain inhibitor, calpastatin, during apoptosis. Cell Death Differ. 1998;5(12): 1028-1033.
35. Doonan F, Donovan M, Cotter TG. Activation of multiple pathways during photoreceptor apoptosis in the rd mouse. Invest Ophthal-mol Vis Sci. 2005;46(10):3530-3538.
36. Sanges D, Comitato A, Tammaro R, Marigo V. Apoptosis in retinal degeneration involves cross-talk between apoptosis-inducing factor (AIF) and caspase-12 and is blocked by calpain inhibitors. Proc Natl Acad Sci USA. 2006;103(46):17366-17371.