-
1
-
-
0028020515
-
Calpain inhibitor AK295 protects neurons from focal brain ischemia. Effects of postocclusion intra-arterial administration
-
R.T. Bartus, N.J. Hayward, P.J. Elliott, S.D. Sawyer, K.L. Baker, R.L. Dean, A. Akiyama, J.A. Straub, S.L. Harbeson, and Z. Li Calpain inhibitor AK295 protects neurons from focal brain ischemia. Effects of postocclusion intra-arterial administration Stroke 25 1994 2265 2270
-
(1994)
Stroke
, vol.25
, pp. 2265-2270
-
-
Bartus, R.T.1
Hayward, N.J.2
Elliott, P.J.3
Sawyer, S.D.4
Baker, K.L.5
Dean, R.L.6
Akiyama, A.7
Straub, J.A.8
Harbeson, S.L.9
Li, Z.10
-
2
-
-
0033540078
-
Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons
-
J.A. Bibb, G.L. Snyder, A. Nishi, Z. Yan, L. Meijer, A.A. Fienberg, L.H. Tsai, Y.T. Kwon, J.A. Girault, A.J. Czernik, R.L. Huganir, H.C. Hemmings Jr., A.C. Nairn, and P. Greengard Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons Nature 402 1999 669 671
-
(1999)
Nature
, vol.402
, pp. 669-671
-
-
Bibb, J.A.1
Snyder, G.L.2
Nishi, A.3
Yan, Z.4
Meijer, L.5
Fienberg, A.A.6
Tsai, L.H.7
Kwon, Y.T.8
Girault, J.A.9
Czernik, A.J.10
Huganir, R.L.11
Hemmings Jr., H.C.12
Nairn, A.C.13
Greengard, P.14
-
3
-
-
0028178139
-
2+ entry via AMPA/KA receptors and excitotoxicity in cultured cerebellar Purkinje cells
-
2+ entry via AMPA/KA receptors and excitotoxicity in cultured cerebellar Purkinje cells J. Neurosci. 14 1994 187 197
-
(1994)
J. Neurosci.
, vol.14
, pp. 187-197
-
-
Brorson, J.R.1
Manzolillo, P.A.2
Miller, R.J.3
-
4
-
-
0029015969
-
Delayed antagonism of calpain reduces excitotoxicity in cultured neurons
-
J.R. Brorson, C.J. Marcuccilli, and R.J. Miller Delayed antagonism of calpain reduces excitotoxicity in cultured neurons Stroke 26 1995 1259 1266
-
(1995)
Stroke
, vol.26
, pp. 1259-1266
-
-
Brorson, J.R.1
Marcuccilli, C.J.2
Miller, R.J.3
-
5
-
-
0025943535
-
Blockade of the AMPA receptor prevents CA1 hippocampal injury following severe but transient forebrain ischemia in adult rats
-
A.M. Buchan, H. Li, S. Cho, and W.A. Pulsinelli Blockade of the AMPA receptor prevents CA1 hippocampal injury following severe but transient forebrain ischemia in adult rats Neurosci. Lett. 132 1991 255 258
-
(1991)
Neurosci. Lett.
, vol.132
, pp. 255-258
-
-
Buchan, A.M.1
Li, H.2
Cho, S.3
Pulsinelli, W.A.4
-
6
-
-
0032748413
-
Emergence of excitotoxicity in cultured forebrain neurons coincides with larger glutamate-stimulated [Ca(2+)](i) increases and NMDA receptor mRNA levels
-
C. Cheng, D.M. Fass, and I.J. Reynolds Emergence of excitotoxicity in cultured forebrain neurons coincides with larger glutamate-stimulated [Ca(2+)](i) increases and NMDA receptor mRNA levels Brain Res. 849 1999 97 108
-
(1999)
Brain Res.
, vol.849
, pp. 97-108
-
-
Cheng, C.1
Fass, D.M.2
Reynolds, I.J.3
-
8
-
-
0034805169
-
The levels of cdk5 and p35 proteins and tau phosphorylation are reduced during neuronal apoptosis
-
P. Kerokoski, T. Suuronen, A. Salminen, H. Soininen, and T. Pirttilä The levels of cdk5 and p35 proteins and tau phosphorylation are reduced during neuronal apoptosis Biochem. Biophys. Res. Commun. 280 2001 998 1002
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.280
, pp. 998-1002
-
-
Kerokoski, P.1
Suuronen, T.2
Salminen, A.3
Soininen, H.4
Pirttilä, T.5
-
9
-
-
0036434290
-
Cleavage of the cyclin-dependent kinase 5 activator p35 to p25 does not induce tau hyperphosphorylation
-
P. Kerokoski, T. Suuronen, A. Salminen, H. Soininen, and T. Pirttilä Cleavage of the cyclin-dependent kinase 5 activator p35 to p25 does not induce tau hyperphosphorylation Biochem. Biophys. Res. Commun. 298 2002 693 698
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.298
, pp. 693-698
-
-
Kerokoski, P.1
Suuronen, T.2
Salminen, A.3
Soininen, H.4
Pirttilä, T.5
-
10
-
-
0037109186
-
Influence of phosphorylation of p35, an activator of cyclin-dependent kinase 5 (cdk5), on the proteolysis of p35
-
P. Kerokoski, T. Suuronen, A. Salminen, H. Soininen, and T. Pirttilä Influence of phosphorylation of p35, an activator of cyclin-dependent kinase 5 (cdk5), on the proteolysis of p35 Brain Res. 106 2002 50 56
-
(2002)
Brain Res.
, vol.106
, pp. 50-56
-
-
Kerokoski, P.1
Suuronen, T.2
Salminen, A.3
Soininen, H.4
Pirttilä, T.5
-
11
-
-
0034595834
-
Calpain-dependent proteolytic cleavage of the p35 cyclin-dependent kinase 5 activator to p25
-
G. Kusakawa, T. Saito, R. Onuki, K. Ishiguro, T. Kishimoto, and S. Hisanaga Calpain-dependent proteolytic cleavage of the p35 cyclin-dependent kinase 5 activator to p25 J. Biol. Chem. 275 2000 17166 17172
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 17166-17172
-
-
Kusakawa, G.1
Saito, T.2
Onuki, R.3
Ishiguro, K.4
Kishimoto, T.5
Hisanaga, S.6
-
12
-
-
0034611632
-
Regulation of N-cadherin-mediated adhesion by the p35-Cdk5 kinase
-
Y.T. Kwon, A. Gupta, Y. Zhou, M. Nikolic, and L.H. Tsai Regulation of N-cadherin-mediated adhesion by the p35-Cdk5 kinase Curr. Biol. 10 2000 363 372
-
(2000)
Curr. Biol.
, vol.10
, pp. 363-372
-
-
Kwon, Y.T.1
Gupta, A.2
Zhou, Y.3
Nikolic, M.4
Tsai, L.H.5
-
13
-
-
0034682414
-
Neurotoxicity induces cleavage of p35 to p25 by calpain
-
M.S. Lee, Y.T. Kwon, M. Li, J. Peng, R.M. Friedlander, and L.H. Tsai Neurotoxicity induces cleavage of p35 to p25 by calpain Nature 405 2000 360 364
-
(2000)
Nature
, vol.405
, pp. 360-364
-
-
Lee, M.S.1
Kwon, Y.T.2
Li, M.3
Peng, J.4
Friedlander, R.M.5
Tsai, L.H.6
-
14
-
-
0035940422
-
Regulation of NMDA receptors by cyclin-dependent kinase-5
-
B.S. Li, M.K. Sun, L. Zhang, S. Takahashi, W. Ma, L. Vinade, A.B. Kulkarni, R.O. Brady, and H.C. Pant Regulation of NMDA receptors by cyclin-dependent kinase-5 Proc. Natl. Acad. Sci. U.S.A. 98 2001 12742 12747
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 12742-12747
-
-
Li, B.S.1
Sun, M.K.2
Zhang, L.3
Takahashi, S.4
Ma, W.5
Vinade, L.6
Kulkarni, A.B.7
Brady, R.O.8
Pant, H.C.9
-
15
-
-
0033915457
-
Processing of cdk5 activator p35 to its truncated form (p25) by calpain in acutely injured neuronal cells
-
R. Nath, M. Davis, A.W. Probert, N.C. Kupina, X. Ren, G.P. Schielke, and K.K. Wang Processing of cdk5 activator p35 to its truncated form (p25) by calpain in acutely injured neuronal cells Biochem. Biophys. Res. Commun. 274 2000 16 21
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.274
, pp. 16-21
-
-
Nath, R.1
Davis, M.2
Probert, A.W.3
Kupina, N.C.4
Ren, X.5
Schielke, G.P.6
Wang, K.K.7
-
16
-
-
17744368458
-
Deregulation of Cdk5 in a mouse model of ALS: Toxicity alleviated by perikaryal neurofilament inclusions
-
M.D. Nguyen, R.C. Lariviere, and J.P. Julien Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions Neuron 30 2001 135 147
-
(2001)
Neuron
, vol.30
, pp. 135-147
-
-
Nguyen, M.D.1
Lariviere, R.C.2
Julien, J.P.3
-
17
-
-
0032504964
-
The p35/Cdk5 kinase is a neuron-specific Rac effector that inhibits Pak1 activity
-
M. Nikolic, M.M. Chou, W. Lu, B.J. Mayer, and L.H. Tsai The p35/Cdk5 kinase is a neuron-specific Rac effector that inhibits Pak1 activity Nature 395 1998 194 198
-
(1998)
Nature
, vol.395
, pp. 194-198
-
-
Nikolic, M.1
Chou, M.M.2
Lu, W.3
Mayer, B.J.4
Tsai, L.H.5
-
18
-
-
0029966469
-
The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation
-
M. Nikolic, H. Dudek, Y.T. Kwon, Y.F. Ramos, and L.H. Tsai The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation Genes Dev. 10 1996 816 825
-
(1996)
Genes Dev.
, vol.10
, pp. 816-825
-
-
Nikolic, M.1
Dudek, H.2
Kwon, Y.T.3
Ramos, Y.F.4
Tsai, L.H.5
-
19
-
-
0029768093
-
Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death
-
T. Ohshima, J.M. Ward, C.G. Huh, G. Longenecker, H.C. Veeranna, R.O. Pant, L.J. Brady, A.B. Martin, and Kulkarni Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death Proc. Natl. Acad. Sci. U.S.A. 93 1996 11173 11178
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 11173-11178
-
-
Ohshima, T.1
Ward, J.M.2
Huh, C.G.3
Longenecker, G.4
Veeranna, H.C.5
Pant, R.O.6
Brady, L.J.7
Martin, A.B.8
Kulkarni9
-
20
-
-
0035684155
-
The Cdk5-p35 kinase associates with the Golgi apparatus and regulates membrane traffic
-
G. Paglini, L. Peris, J. Diez-Guerra, S. Quiroga, and A. Caceres The Cdk5-p35 kinase associates with the Golgi apparatus and regulates membrane traffic EMBO Rep. 2 2001 1139 1144
-
(2001)
EMBO Rep.
, vol.2
, pp. 1139-1144
-
-
Paglini, G.1
Peris, L.2
Diez-Guerra, J.3
Quiroga, S.4
Caceres, A.5
-
21
-
-
0033540060
-
Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration
-
G.N. Patrick, L. Zukerberg, M. Nikolic, S. de la Monte, P. Dikkes, and L.H. Tsai Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration Nature 402 1999 615 622
-
(1999)
Nature
, vol.402
, pp. 615-622
-
-
Patrick, G.N.1
Zukerberg, L.2
Nikolic, M.3
De La Monte, S.4
Dikkes, P.5
Tsai, L.H.6
-
22
-
-
0026452868
-
Switch in glutamate receptor subunit gene expression in CA1 subfield of hippocampus following global ischemia in rats
-
D.E. Pellegrini-Giampietro, R.S. Zukin, M.V. Bennett, S. Cho, and W.A. Pulsinelli Switch in glutamate receptor subunit gene expression in CA1 subfield of hippocampus following global ischemia in rats Proc. Natl. Acad. Sci. U.S.A. 89 1992 10499 10503
-
(1992)
Proc. Natl. Acad. Sci. U.S.A.
, vol.89
, pp. 10499-10503
-
-
Pellegrini-Giampietro, D.E.1
Zukin, R.S.2
Bennett, M.V.3
Cho, S.4
Pulsinelli, W.A.5
-
23
-
-
0021743001
-
Blockade of N-methyl-d-aspartate receptors may protect against ischemic damage in the brain
-
R.P. Simon, J.H. Swan, T. Griffiths, and B.S. Meldrum Blockade of N-methyl-d-aspartate receptors may protect against ischemic damage in the brain Science 226 1984 850 852
-
(1984)
Science
, vol.226
, pp. 850-852
-
-
Simon, R.P.1
Swan, J.H.2
Griffiths, T.3
Meldrum, B.S.4
-
24
-
-
0027080523
-
Complex pharmacological properties of recombinant alpha-amino-3-hydroxy- 5-methyl-4-isoxazole propionate receptor subtypes
-
E. Stein, J.A. Cox, P.H. Seeburg, and T.A. Verdoorn Complex pharmacological properties of recombinant alpha-amino-3-hydroxy-5-methyl-4- isoxazole propionate receptor subtypes Mol. Pharmacol. 42 1992 864 871
-
(1992)
Mol. Pharmacol.
, vol.42
, pp. 864-871
-
-
Stein, E.1
Cox, J.A.2
Seeburg, P.H.3
Verdoorn, T.A.4
-
25
-
-
0023092256
-
A new type of glutamate receptor linked to inositol phospholipid metabolism
-
H. Sugiyama, I. Ito, and C. Hirono A new type of glutamate receptor linked to inositol phospholipid metabolism Nature 325 1987 531 533
-
(1987)
Nature
, vol.325
, pp. 531-533
-
-
Sugiyama, H.1
Ito, I.2
Hirono, C.3
-
26
-
-
0035951413
-
Calpain-mediated degradation of p35 to p25 in postmortem human and rat brains
-
S. Taniguchi, Y. Fujita, S. Hayashi, A. Kakita, H. Takahashi, S. Murayama, T.C. Saido, S. Hisanaga, T. Iwatsubo, and M. Hasegawa Calpain-mediated degradation of p35 to p25 in postmortem human and rat brains FEBS Lett. 489 2001 46 50
-
(2001)
FEBS Lett.
, vol.489
, pp. 46-50
-
-
Taniguchi, S.1
Fujita, Y.2
Hayashi, S.3
Kakita, A.4
Takahashi, H.5
Murayama, S.6
Saido, T.C.7
Hisanaga, S.8
Iwatsubo, T.9
Hasegawa, M.10
-
27
-
-
0035012468
-
Regulation of spontaneous inhibitory synaptic transmission by endogenous glutamate via non-NMDA receptors in cultured rat hippocampal neurons
-
M. Vignes Regulation of spontaneous inhibitory synaptic transmission by endogenous glutamate via non-NMDA receptors in cultured rat hippocampal neurons Neuropharmacology 40 2001 737 748
-
(2001)
Neuropharmacology
, vol.40
, pp. 737-748
-
-
Vignes, M.1
-
28
-
-
0141542665
-
Cdk5 activation induces hippocampal CA1 cell death by directly phosphorylating NMDA receptors
-
J. Wang, S. Liu, Y. Fu, J.H. Wang, and Y. Lu Cdk5 activation induces hippocampal CA1 cell death by directly phosphorylating NMDA receptors Nat. Neurosci. 6 2003 1039 1047
-
(2003)
Nat. Neurosci.
, vol.6
, pp. 1039-1047
-
-
Wang, J.1
Liu, S.2
Fu, Y.3
Wang, J.H.4
Lu, Y.5
|