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Volumn 26, Issue 10, 2012, Pages 1281-1292

CD8 + T cells in preventing HIV infection and disease

Author keywords

CD8 + T cell; HIV disease; HIV infection; HIV vaccine

Indexed keywords

CD27 ANTIGEN; CD28 ANTIGEN; CD45RA ANTIGEN; CD45RO ANTIGEN; CHEMOKINE RECEPTOR CCR7; EPITOPE; GAMMA INTERFERON; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; INTERLEUKIN 2; INTERLEUKIN 7 RECEPTOR; L SELECTIN; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; PROGRAMMED DEATH 1 RECEPTOR; T LYMPHOCYTE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; VIRUS RNA;

EID: 84862744172     PISSN: 02699370     EISSN: 14735571     Source Type: Journal    
DOI: 10.1097/QAD.0b013e328353bcaf     Document Type: Review
Times cited : (68)

References (182)
  • 1
    • 84862765346 scopus 로고    scopus 로고
    • WHO
    • WHO. http://www.who.int/hiv/pub/progress-report2011/en/index.html.
  • 2
    • 84862736314 scopus 로고    scopus 로고
    • The evolving epidemiology of HIV/AIDS
    • De Cock KM, Jaffe HW, Curran JW. The evolving epidemiology of HIV/AIDS. AIDS 2012; 26:1205-1213.
    • (2012) AIDS , vol.26 , pp. 1205-1213
    • De Cock, K.M.1    Jaffe, H.W.2    Curran, J.W.3
  • 4
    • 83955164274 scopus 로고    scopus 로고
    • Antiretroviral prophylaxis: A defining moment in HIV control
    • Karim SS, Karim QA. Antiretroviral prophylaxis: a defining moment in HIV control. Lancet 2011; 378:e23-e25.
    • (2011) Lancet , vol.378
    • Karim, S.S.1    Karim, Q.A.2
  • 5
    • 79960372412 scopus 로고    scopus 로고
    • Drug concentrations after topical and oral antiretroviral preexposure prophylaxis: Implications for HIV prevention in women
    • Karim SS, Kashuba AD, Werner L, Karim QA. Drug concentrations after topical and oral antiretroviral preexposure prophylaxis: implications for HIV prevention in women. Lancet 2011; 378:279-281.
    • (2011) Lancet , vol.378 , pp. 279-281
    • Karim, S.S.1    Kashuba, A.D.2    Werner, L.3    Karim, Q.A.4
  • 9
    • 0033681160 scopus 로고    scopus 로고
    • Biphasic decay of latently infected CD4RT cells in acute human immunodeficiency virus type 1 infection
    • Blankson JN, Finzi D, Pierson TC, Sabundayo BP, Chadwick K, Margolick JB, et al. Biphasic decay of latently infected CD4RT cells in acute human immunodeficiency virus type 1 infection. J Infect Dis 2000; 182:1636-1642.
    • (2000) J Infect Dis , vol.182 , pp. 1636-1642
    • Blankson, J.N.1    Finzi, D.2    Pierson, T.C.3    Sabundayo, B.P.4    Chadwick, K.5    Margolick, J.B.6
  • 10
    • 59049094482 scopus 로고    scopus 로고
    • HIV pathogenesis: 25 years of progress and persistent challenges
    • Levy JA. HIV pathogenesis: 25 years of progress and persistent challenges. AIDS 2009; 23:147-160.
    • (2009) AIDS , vol.23 , pp. 147-160
    • Levy, J.A.1
  • 11
    • 79551578453 scopus 로고    scopus 로고
    • Early events in sexual transmission of HIV and SIV and opportunities for interventions
    • Haase AT. Early events in sexual transmission of HIV and SIV and opportunities for interventions. Annu Rev Med 2011; 62:127-139.
    • (2011) Annu Rev Med , vol.62 , pp. 127-139
    • Haase, A.T.1
  • 12
    • 38849123518 scopus 로고    scopus 로고
    • CD8R T cells from SIV elite controller macaques recognize Mamu-BM08-bound epitopes and select for widespread viral variation
    • Loffredo JT, Friedrich TC, Leon EJ, Stephany JJ, Rodrigues DS, Spencer SP, et al. CD8R T cells from SIV elite controller macaques recognize Mamu-BM08-bound epitopes and select for widespread viral variation. PLoS One 2007; 2:e1152.
    • (2007) PLoS One , vol.2
    • Loffredo, J.T.1    Friedrich, T.C.2    Leon, E.J.3    Stephany, J.J.4    Rodrigues, D.S.5    Spencer, S.P.6
  • 13
    • 34548689151 scopus 로고    scopus 로고
    • Human Immunodeficiency Virus Controllers: Mechanisms of Durable Virus Control in the Absence of Antiretroviral Therapy
    • DOI 10.1016/j.immuni.2007.08.010, PII S1074761307004141
    • Deeks SG, Walker BD. Human immunodeficiency virus controllers: mechanisms of durable virus control in the absence of antiretroviral therapy. Immunity 2007; 27:406-416. (Pubitemid 47418678)
    • (2007) Immunity , vol.27 , Issue.3 , pp. 406-416
    • Deeks, S.G.1    Walker, B.D.2
  • 16
    • 50149101954 scopus 로고    scopus 로고
    • Genetic characterization of human immunodeficiency virus type 1 in elite controllers: Lack of gross genetic defects or common amino acid changes
    • Miura T, Brockman MA, Brumme CJ, Brumme ZL, Carlson JM, Pereyra F, et al. Genetic characterization of human immunodeficiency virus type 1 in elite controllers: lack of gross genetic defects or common amino acid changes. J Virol 2008; 82:8422-8430.
    • (2008) J Virol , vol.82 , pp. 8422-8430
    • Miura, T.1    Brockman, M.A.2    Brumme, C.J.3    Brumme, Z.L.4    Carlson, J.M.5    Pereyra, F.6
  • 17
    • 33847176917 scopus 로고    scopus 로고
    • Isolation and characterization of replication-competent human immunodeficiency virus type 1 from a subset of elite suppressors
    • Blankson JN, Bailey JR, Thayil S, Yang HC, Lassen K, Lai J, et al. Isolation and characterization of replication-competent human immunodeficiency virus type 1 from a subset of elite suppressors. J Virol 2007; 81:2508-2518.
    • (2007) J Virol , vol.81 , pp. 2508-2518
    • Blankson, J.N.1    Bailey, J.R.2    Thayil, S.3    Yang, H.C.4    Lassen, K.5    Lai, J.6
  • 18
    • 78649431227 scopus 로고    scopus 로고
    • HIV-1 continues to replicate and evolve in patients with natural control of HIV infection
    • Mens H, Kearney M, Wiegand A, Shao W, Schonning K, Gerstoft J, et al. HIV-1 continues to replicate and evolve in patients with natural control of HIV infection. J Virol 2010; 84:12971-12981.
    • (2010) J Virol , vol.84 , pp. 12971-12981
    • Mens, H.1    Kearney, M.2    Wiegand, A.3    Shao, W.4    Schonning, K.5    Gerstoft, J.6
  • 19
    • 79960997521 scopus 로고    scopus 로고
    • Viral suppression of multiple escape mutants by de novo CD8(R) T cell responses in a human immunodeficiency virus-1 infected elite suppressor
    • O'Connell KA, Hegarty RW, Siliciano RF, Blankson JN. Viral suppression of multiple escape mutants by de novo CD8(R) T cell responses in a human immunodeficiency virus-1 infected elite suppressor. Retrovirology 2011; 8:63.
    • (2011) Retrovirology , vol.8 , pp. 63
    • O'Connell, K.A.1    Hegarty, R.W.2    Siliciano, R.F.3    Blankson, J.N.4
  • 20
    • 80051873375 scopus 로고    scopus 로고
    • CD8(R) T cells: Foot soldiers of the immune system
    • Zhang N, Bevan MJ. CD8(R) T cells: foot soldiers of the immune system. Immunity 2011; 35:161-168.
    • (2011) Immunity , vol.35 , pp. 161-168
    • Zhang, N.1    Bevan, M.J.2
  • 22
    • 0035348175 scopus 로고    scopus 로고
    • + T cell differentiation: Initial antigen encounter triggers a developmental program in naïve cells
    • Kaech SM, Ahmed R. Memory CD8R T cell differentiation: initial antigen encounter triggers a developmental program in naive cells. Nat Immunol 2001; 2:415-422. (Pubitemid 33706139)
    • (2001) Nature Immunology , vol.2 , Issue.5 , pp. 415-422
    • Kaech, S.M.1    Ahmed, R.2
  • 23
    • 0033554726 scopus 로고    scopus 로고
    • Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
    • Sallusto F, Lenig D, Forster R, Lipp M, Lanzavecchia A. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 1999; 401:708-712.
    • (1999) Nature , vol.401 , pp. 708-712
    • Sallusto, F.1    Lenig, D.2    Forster, R.3    Lipp, M.4    Lanzavecchia, A.5
  • 25
    • 0035295675 scopus 로고    scopus 로고
    • Vehicles for genetic vaccines against human immunodeficiency virus: induction of T cell-mediated immune responses
    • Hanke T. Vehicles for genetic vaccines against human immunodeficiency virus: induction of T cell-mediated immune responses. Curr Mol Med 2001; 1:123-135. (Pubitemid 33772973)
    • (2001) Current Molecular Medicine , vol.1 , Issue.1 , pp. 123-135
    • Hanke, T.1
  • 26
    • 0024243176 scopus 로고
    • Use of vaccinia virus vectors for development of AIDS vaccines
    • Moss B. Use of vaccinia virus vectors for development of AIDS vaccines. AIDS 1988; 2 (Suppl 1):S103-S105. (Pubitemid 19042845)
    • (1988) AIDS , vol.2 , Issue.SUPPL. 1
    • Moss, B.1
  • 27
    • 17644419950 scopus 로고    scopus 로고
    • T cell vaccines for microbial infections
    • DOI 10/nm1212
    • Robinson HL, Amara RR. T cell vaccines for microbial infections. Nat Med 2005; 11:S25-S32. (Pubitemid 40562301)
    • (2005) Nature Medicine , vol.11 , Issue.4 SUPPL.
    • Robinson, H.L.1    Amara, R.R.2
  • 29
    • 63449103666 scopus 로고    scopus 로고
    • Visualizing antigen-specific and infected cells in situ predicts outcomes in early viral infection
    • Li Q, Skinner PJ, Ha SJ, Duan L, Mattila TL, Hage A, et al. Visualizing antigen-specific and infected cells in situ predicts outcomes in early viral infection. Science 2009; 323:1726-1729.
    • (2009) Science , vol.323 , pp. 1726-1729
    • Li, Q.1    Skinner, P.J.2    Ha, S.J.3    Duan, L.4    Mattila, T.L.5    Hage, A.6
  • 30
    • 33746190871 scopus 로고    scopus 로고
    • Cutting edge: Central memory T cells do not show accelerated proliferation or tissue infiltration in response to localized herpes simplex virus-1 infection
    • Stock AT, Jones CM, Heath WR, Carbone FR. Cutting edge: central memory T cells do not show accelerated proliferation or tissue infiltration in response to localized herpes simplex virus-1 infection. J Immunol 2006; 177:1411-1415. (Pubitemid 44092472)
    • (2006) Journal of Immunology , vol.177 , Issue.3 , pp. 1411-1415
    • Stock, A.T.1    Jones, C.M.2    Heath, W.R.3    Carbone, F.R.4
  • 31
    • 77950343170 scopus 로고    scopus 로고
    • Memories that last forever: Strategies for optimizing vaccine T-cell memory
    • Ahlers JD, Belyakov IM. Memories that last forever: strategies for optimizing vaccine T-cell memory. Blood 2010; 115:1678-1689.
    • (2010) Blood , vol.115 , pp. 1678-1689
    • Ahlers, J.D.1    Belyakov, I.M.2
  • 32
    • 0028041344 scopus 로고
    • + cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection
    • Borrow P, Lewicki H, Hahn BH, Shaw GM, Oldstone MB. Virus-specific CD8R cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection. J Virol 1994; 68:6103-6110. (Pubitemid 24258634)
    • (1994) Journal of Virology , vol.68 , Issue.9 , pp. 6103-6110
    • Borrow, P.1    Lewicki, H.2    Hahn, B.H.3    Shaw, G.M.4    Oldstone, M.B.A.5
  • 33
    • 0028337166 scopus 로고
    • Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome
    • Koup RA, Safrit JT, Cao Y, Andrews CA, McLeod G, Borkowsky W, et al. Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome. J Virol 1994; 68:4650-4655. (Pubitemid 24183063)
    • (1994) Journal of Virology , vol.68 , Issue.7 , pp. 4650-4655
    • Koup, R.A.1    Safrit, J.T.2    Cao, Y.3    Andrews, C.A.4    McLeod, G.5    Borkowsky, W.6    Farthing, C.7    Ho, D.D.8
  • 36
    • 0031985775 scopus 로고    scopus 로고
    • Administration of an anti-CD8 monoclonal antibody interferes with the clearance of chimeric simian/human immunodeficiency virus during primary infections of rhesus macaques
    • Matano T, Shibata R, Siemon C, Connors M, Lane HC, Martin MA. Administration of an anti-CD8 monoclonal antibody interferes with the clearance of chimeric simian/human immunodeficiency virus during primary infections of rhesus macaques. J Virol 1998; 72:164-169. (Pubitemid 28048825)
    • (1998) Journal of Virology , vol.72 , Issue.1 , pp. 164-169
    • Matano, T.1    Shibata, R.2    Siemon, C.3    Connors, M.4    Lane, H.C.5    Martin, M.A.6
  • 38
    • 0033524838 scopus 로고    scopus 로고
    • Control of viremia in simian immunodeficiency virus infection byCD8Rlymphocytes
    • Schmitz JE. Control of viremia in simian immunodeficiency virus infection byCD8Rlymphocytes. Science 1999; 283:857-860.
    • (1999) Science , vol.283 , pp. 857-860
    • Schmitz, J.E.1
  • 42
    • 0022967777 scopus 로고
    • + lymphocytes can control HIV infection in vitro by suppressing virus replication
    • Walker CM, Moody DJ, Stites DP, Levy JA. CD8Rlymphocytes can control HIV infection in vitro by suppressing virus replication. Science 1986; 234:1563-1566. (Pubitemid 17125280)
    • (1986) Science , vol.234 , Issue.4783 , pp. 1563-1566
    • Walker, C.M.1    Moody, D.J.2    Stites, D.P.3    Levy, J.A.4
  • 44
    • 0023228920 scopus 로고
    • Sequence of simian immunodeficiency virus from macaque and its relationship to other human and simian retroviruses
    • DOI 10.1038/328543a0
    • Chakrabarti L, Guyader M, Alizon M, Daniel MD, Desrosiers RC, Tiollais P, et al. Sequence of simian immunodeficiency virus from macaque and its relationship to other human and simian retroviruses. Nature 1987; 328:543-547. (Pubitemid 17098358)
    • (1987) Nature , vol.328 , Issue.6130 , pp. 543-547
    • Chakrabarti, L.1    Guyader, M.2    Alizon, M.3
  • 45
    • 22144469118 scopus 로고    scopus 로고
    • Nonhuman primate models for AIDS vaccine research
    • Hu SL. Nonhuman primate models for AIDS vaccine research. Curr Drug Targets Infect Disord 2005; 5:193-201.
    • (2005) Curr Drug Targets Infect Disord , vol.5 , pp. 193-201
    • Hu, S.L.1
  • 46
    • 56649095805 scopus 로고    scopus 로고
    • Relevance of studying T cell responses in SIV-infected rhesus macaques
    • Valentine LE, Watkins DI. Relevance of studying T cell responses in SIV-infected rhesus macaques. Trends Microbiol 2008; 16:605-611.
    • (2008) Trends Microbiol , vol.16 , pp. 605-611
    • Valentine, L.E.1    Watkins, D.I.2
  • 47
    • 33745363316 scopus 로고    scopus 로고
    • Immunopathogenesis of acute AIDS virus infection
    • DOI 10.1016/j.coi.2006.05.001, PII S0952791506000951
    • Picker LJ. Immunopathogenesis of acute AIDS virus infection. Curr Opin Immunol 2006; 18:399-405. (Pubitemid 43947575)
    • (2006) Current Opinion in Immunology , vol.18 , Issue.4 , pp. 399-405
    • Picker, L.J.1
  • 50
    • 0038112112 scopus 로고    scopus 로고
    • AIDS vaccines: Back to 'plan A'
    • Check E. AIDS vaccines: back to 'plan A'. Nature 2003; 423:912-914.
    • (2003) Nature , vol.423 , pp. 912-914
    • Check, E.1
  • 51
    • 66049157864 scopus 로고    scopus 로고
    • Low-dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates human mucosal infection by HIV-1
    • Keele BF, Li H, Learn GH, Hraber P, Giorgi EE, Grayson T, et al. Low-dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates human mucosal infection by HIV-1. J Exp Med 2009; 206:1117-1134.
    • (2009) J Exp Med , vol.206 , pp. 1117-1134
    • Keele, B.F.1    Li, H.2    Learn, G.H.3    Hraber, P.4    Giorgi, E.E.5    Grayson, T.6
  • 53
    • 0023685463 scopus 로고
    • HIV-1 gag-specific cytotoxic T lymphocytes defined with recombinant vaccinia virus and synthetic peptides
    • Nixon DF, Townsend AR, Elvin JG, Rizza CR, Gallwey J, McMichael AJ. HIV-1 gag-specific cytotoxic T lymphocytes defined with recombinant vaccinia virus and synthetic peptides. Nature 1988; 336:484-487.
    • (1988) Nature , vol.336 , pp. 484-487
    • Nixon, D.F.1    Townsend, A.R.2    Elvin, J.G.3    Rizza, C.R.4    Gallwey, J.5    McMichael, A.J.6
  • 55
    • 0025952527 scopus 로고
    • Analysis of alternatively spliced human immunodeficiency virus type-1 mRNA species, one of which encodes a novel tat-env fusion protein
    • Furtado MR, Balachandran R, Gupta P, Wolinsky SM. Analysis of alternatively spliced human immunodeficiency virus type-1 mRNA species, one of which encodes a novel tat-env fusion protein. Virology 1991; 185:258-270.
    • (1991) Virology , vol.185 , pp. 258-270
    • Furtado, M.R.1    Balachandran, R.2    Gupta, P.3    Wolinsky, S.M.4
  • 57
    • 0034699512 scopus 로고    scopus 로고
    • Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia
    • Allen TM, O'Connor DH, Jing P, Dzuris JL, Mothe BR, Vogel TU, et al. Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia. Nature 2000; 407:386-390.
    • (2000) Nature , vol.407 , pp. 386-390
    • Allen, T.M.1    O'Connor, D.H.2    Jing, P.3    Dzuris, J.L.4    Mothe, B.R.5    Vogel, T.U.6
  • 58
    • 0034660504 scopus 로고    scopus 로고
    • Simian immunodeficiency virus evades a dominant epitope-specific cytotoxic T lymphocyte response through a mutation resulting in the accelerated dissociation of viral peptide and MHC class I
    • Chen ZW, Craiu A, Shen L, Kuroda MJ, Iroku UC, Watkins DI, et al. Simian immunodeficiency virus evades a dominant epitope-specific cytotoxic T lymphocyte response through a mutation resulting in the accelerated dissociation of viral peptide and MHC class I. J Immunol 2000; 164:6474-6479. (Pubitemid 30408831)
    • (2000) Journal of Immunology , vol.164 , Issue.12 , pp. 6474-6479
    • Chen, Z.W.1    Craiu, A.2    Shen, L.3    Kuroda, M.J.4    Iroku, U.C.5    Watkins, D.I.6    Voss, G.7    Letvin, N.L.8
  • 60
    • 67449147145 scopus 로고    scopus 로고
    • The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection
    • Goonetilleke N, Liu MK, Salazar-Gonzalez JF, Ferrari G, Giorgi E, Ganusov VV, et al. The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection. J Exp Med 2009; 206:1253-1272.
    • (2009) J Exp Med , vol.206 , pp. 1253-1272
    • Goonetilleke, N.1    Liu, M.K.2    Salazar-Gonzalez, J.F.3    Ferrari, G.4    Giorgi, E.5    Ganusov, V.V.6
  • 62
    • 0035667633 scopus 로고    scopus 로고
    • Understanding cytotoxic T-lymphocyte escape during simian immunodeficiency virus infection
    • DOI 10.1034/j.1600-065X.2001.1830110.x
    • O'Connor D, Friedrich T, Hughes A, Allen TM, Watkins D. Understanding cytotoxic T-lymphocyte escape during simian immunodeficiency virus infection. Immunol Rev 2001; 183:115-126. (Pubitemid 34015443)
    • (2001) Immunological Reviews , vol.183 , pp. 115-126
    • O'Connor, D.1    Friedrich, T.2    Hughes, A.3    Allen, T.M.4    Watkins, D.5
  • 64
    • 23844539631 scopus 로고    scopus 로고
    • Human immunodeficiency virus mutations during the first month of infection are preferentially found in known cytotoxic T-lymphocyte epitopes
    • DOI 10.1128/JVI.79.17.11523-11528.2005
    • Bernardin F, Kong D, Peddada L, Baxter-Lowe LA, Delwart E. Human immunodeficiency virus mutations during the first month of infection are preferentially found in known cytotoxic T-lymphocyte epitopes. J Virol 2005; 79:11523-11528. (Pubitemid 41170695)
    • (2005) Journal of Virology , vol.79 , Issue.17 , pp. 11523-11528
    • Bernardin, F.1    Kong, D.2    Peddada, L.3    Baxter-Lowe, L.A.4    Delwart, E.5
  • 69
    • 0035808775 scopus 로고    scopus 로고
    • Clustered mutations in HIV-1 gag are consistently required for escape from HLA-B27-restricted cytotoxic T lymphocyte responses
    • Kelleher AD, Long C, Holmes EC, Allen RL, Wilson J, Conlon C, et al. Clustered mutations in HIV-1 gag are consistently required for escape from HLA-B27-restricted cytotoxic T lymphocyte responses. J Exp Med 2001; 193:375-386.
    • (2001) J Exp Med , vol.193 , pp. 375-386
    • Kelleher, A.D.1    Long, C.2    Holmes, E.C.3    Allen, R.L.4    Wilson, J.5    Conlon, C.6
  • 72
    • 33645240933 scopus 로고    scopus 로고
    • Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1
    • Martinez-Picado J, Prado JG, Fry EE, Pfafferott K, Leslie A, Chetty S, et al. Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1. J Virol 2006; 80:3617-3623.
    • (2006) J Virol , vol.80 , pp. 3617-3623
    • Martinez-Picado, J.1    Prado, J.G.2    Fry, E.E.3    Pfafferott, K.4    Leslie, A.5    Chetty, S.6
  • 73
    • 67650924875 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1-specific CD8R T-cell responses during primary infection are major determinants of the viral set point and loss of CD4R T cells
    • Streeck H, Jolin JS, Qi Y, Yassine-Diab B, Johnson RC, Kwon DS, et al. Human immunodeficiency virus type 1-specific CD8R T-cell responses during primary infection are major determinants of the viral set point and loss of CD4R T cells. J Virol 2009; 83:7641-7648.
    • (2009) J Virol , vol.83 , pp. 7641-7648
    • Streeck, H.1    Jolin, J.S.2    Qi, Y.3    Yassine-Diab, B.4    Johnson, R.C.5    Kwon, D.S.6
  • 74
    • 79958030663 scopus 로고    scopus 로고
    • Viral CTL escape mutants are generated in lymph nodes and subsequently become fixed in plasma and rectal mucosa during acute SIV infection of macaques
    • Vanderford TH, Bleckwehl C, Engram JC, Dunham RM, Klatt NR, Feinberg MB, et al. Viral CTL escape mutants are generated in lymph nodes and subsequently become fixed in plasma and rectal mucosa during acute SIV infection of macaques. PLoS Pathog 2011; 7:e1002048.
    • (2011) PLoS Pathog , vol.7
    • Vanderford, T.H.1    Bleckwehl, C.2    Engram, J.C.3    Dunham, R.M.4    Klatt, N.R.5    Feinberg, M.B.6
  • 75
    • 79960137057 scopus 로고    scopus 로고
    • Extensive HLA-driven viral diversity following a narrowsource HIV-1 outbreak in rural China
    • Dong T, Zhang Y, Xu KY, Yan H, James I, Peng Y, et al. Extensive HLA-driven viral diversity following a narrowsource HIV-1 outbreak in rural China. Blood 2011; 118:98-106.
    • (2011) Blood , vol.118 , pp. 98-106
    • Dong, T.1    Zhang, Y.2    Xu, K.Y.3    Yan, H.4    James, I.5    Peng, Y.6
  • 76
    • 67249140561 scopus 로고    scopus 로고
    • HIV evolution in early infection: Selection pressures, patterns of insertion and deletion, and the impact of APOBEC
    • Wood N, Bhattacharya T, Keele BF, Giorgi E, Liu M, Gaschen B, et al. HIV evolution in early infection: selection pressures, patterns of insertion and deletion, and the impact of APOBEC. PLoS Pathog 2009; 5:e1000414.
    • (2009) PLoS Pathog , vol.5
    • Wood, N.1    Bhattacharya, T.2    Keele, B.F.3    Giorgi, E.4    Liu, M.5    Gaschen, B.6
  • 77
    • 33845756711 scopus 로고    scopus 로고
    • Rapid reversion of sequence polymorphisms dominates early human immunodeficiency virus type 1 evolution
    • DOI 10.1128/JVI.01231-06
    • Li B, Gladden AD, Altfeld M, Kaldor JM, Cooper DA, Kelleher AD, et al. Rapid reversion of sequence polymorphisms dominates early human immunodeficiency virus type 1 evolution. J Virol 2007; 81:193-201. (Pubitemid 44975160)
    • (2007) Journal of Virology , vol.81 , Issue.1 , pp. 193-201
    • Li, B.1    Gladden, A.D.2    Altfeld, M.3    Kaldor, J.M.4    Cooper, D.A.5    Kelleher, A.D.6    Allen, T.M.7
  • 78
    • 49849087657 scopus 로고    scopus 로고
    • Human leukocyte antigen-specific polymorphisms in HIV-1 Gag and their association with viral load in chronic untreated infection
    • Brumme ZL, Tao I, Szeto S, Brumme CJ, Carlson JM, Chan D, et al. Human leukocyte antigen-specific polymorphisms in HIV-1 Gag and their association with viral load in chronic untreated infection. AIDS 2008; 22:1277-1286.
    • (2008) AIDS , vol.22 , pp. 1277-1286
    • Brumme, Z.L.1    Tao, I.2    Szeto, S.3    Brumme, C.J.4    Carlson, J.M.5    Chan, D.6
  • 79
    • 59649108841 scopus 로고    scopus 로고
    • Protective HLA class i alleles that restrict acute-phase CD8R T-cell responses are associated with viral escape mutations located in highly conserved regions of human immunodeficiency virus type 1
    • Wang YE, Li B, Carlson JM, Streeck H, Gladden AD, Goodman R, et al. Protective HLA class I alleles that restrict acute-phase CD8R T-cell responses are associated with viral escape mutations located in highly conserved regions of human immunodeficiency virus type 1. J Virol 2009; 83:1845-1855.
    • (2009) J Virol , vol.83 , pp. 1845-1855
    • Wang, Y.E.1    Li, B.2    Carlson, J.M.3    Streeck, H.4    Gladden, A.D.5    Goodman, R.6
  • 80
    • 33750869972 scopus 로고    scopus 로고
    • HLA alleles associated with delayed progression to AIDS contribute strongly to the initial CD8(R) T cell response against HIV-1
    • Altfeld M, Kalife ET, Qi Y, Streeck H, Lichterfeld M, Johnston MN, et al. HLA alleles associated with delayed progression to AIDS contribute strongly to the initial CD8(R) T cell response against HIV-1. PLoS Med 2006; 3:e403.
    • (2006) PLoS Med , vol.3
    • Altfeld, M.1    Kalife, E.T.2    Qi, Y.3    Streeck, H.4    Lichterfeld, M.5    Johnston, M.N.6
  • 81
    • 80055017715 scopus 로고    scopus 로고
    • Fitness costs and diversity of the cytotoxic T lymphocyte (CTL) response determine the rate of CTL escape during acute and chronic phases of HIV infection
    • Ganusov VV, Goonetilleke N, Liu MK, Ferrari G, Shaw GM, McMichael AJ, et al. Fitness costs and diversity of the cytotoxic T lymphocyte (CTL) response determine the rate of CTL escape during acute and chronic phases of HIV infection. J Virol 2011; 85:10518-10528.
    • (2011) J Virol , vol.85 , pp. 10518-10528
    • Ganusov, V.V.1    Goonetilleke, N.2    Liu, M.K.3    Ferrari, G.4    Shaw, G.M.5    McMichael, A.J.6
  • 82
    • 78751640260 scopus 로고    scopus 로고
    • Reduced replication capacity of NL4-3 recombinant viruses encoding reverse transcriptase-integrase sequences from HIV-1 elite controllers
    • Brumme ZL, Li C, Miura T, Sela J, Rosato PC, Brumme CJ, et al. Reduced replication capacity of NL4-3 recombinant viruses encoding reverse transcriptase-integrase sequences from HIV-1 elite controllers. J Acquir Immune Defic Syndr 2011; 56:100-108.
    • (2011) J Acquir Immune Defic Syndr , vol.56 , pp. 100-108
    • Brumme, Z.L.1    Li, C.2    Miura, T.3    Sela, J.4    Rosato, P.C.5    Brumme, C.J.6
  • 83
    • 44949154503 scopus 로고    scopus 로고
    • + T cell efficacy in vaccination and disease
    • DOI 10.1038/nm.f.1774, PII NMF1774
    • Appay V, Douek DC, Price DA. CD8R T cell efficacy in vaccination and disease. Nat Med 2008; 14:623-628. (Pubitemid 351809548)
    • (2008) Nature Medicine , vol.14 , Issue.6 , pp. 623-628
    • Appay, V.1    Douek, D.C.2    Price, D.A.3
  • 88
    • 33646461679 scopus 로고    scopus 로고
    • The high-frequency major histocompatibility complex class i allele Mamu-BM17 is associated with control of simian immunodeficiency virus SIVmac239 replication
    • Yant LJ, Friedrich TC, Johnson RC, May GE, Maness NJ, Enz AM, et al. The high-frequency major histocompatibility complex class I allele Mamu-BM17 is associated with control of simian immunodeficiency virus SIVmac239 replication. J Virol 2006; 80:5074-5077.
    • (2006) J Virol , vol.80 , pp. 5074-5077
    • Yant, L.J.1    Friedrich, T.C.2    Johnson, R.C.3    May, G.E.4    Maness, N.J.5    Enz, A.M.6
  • 90
    • 10644267588 scopus 로고    scopus 로고
    • Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA
    • Kiepiela P, Leslie AJ, Honeyborne I, Ramduth D, Thobakgale C, Chetty S, et al. Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA. Nature 2004; 432:769-775.
    • (2004) Nature , vol.432 , pp. 769-775
    • Kiepiela, P.1    Leslie, A.J.2    Honeyborne, I.3    Ramduth, D.4    Thobakgale, C.5    Chetty, S.6
  • 92
  • 93
    • 79956158037 scopus 로고    scopus 로고
    • An early HIV mutation within an HLA-BM57-restricted T cell epitope abrogates binding to the killer inhibitory receptor 3DL1
    • Brackenridge S, Evans EJ, Toebes M, Goonetilleke N, Liu MK, di Gleria K, et al. An early HIV mutation within an HLA-BM57-restricted T cell epitope abrogates binding to the killer inhibitory receptor 3DL1. J Virol 2011; 85:5415-5422.
    • (2011) J Virol , vol.85 , pp. 5415-5422
    • Brackenridge, S.1    Evans, E.J.2    Toebes, M.3    Goonetilleke, N.4    Liu, M.K.5    Di Gleria, K.6
  • 94
  • 97
    • 3543113110 scopus 로고    scopus 로고
    • Immune escape precedes breakthrough human immunodeficiency virus type 1 viremia and broadening of the cytotoxic T-lymphocyte response in an HLA-B27-positive long-term-nonprogressing child
    • DOI 10.1128/JVI.78.16.8927-8930.2004
    • Feeney ME, Tang Y, Roosevelt KA, Leslie AJ, McIntosh K, Karthas N, et al. Immune escape precedes breakthrough human immunodeficiency virus type 1 viremia and broadening of the cytotoxic T-lymphocyte response in an HLA-B27-positive long-term-nonprogressing child. J Virol 2004; 78:8927-8930. (Pubitemid 39025159)
    • (2004) Journal of Virology , vol.78 , Issue.16 , pp. 8927-8930
    • Feeney, M.E.1    Tang, Y.2    Roosevelt, K.A.3    Leslie, A.J.4    McIntosh, K.5    Karthas, N.6    Walker, B.D.7    Goulder, P.J.R.8
  • 99
    • 78650073132 scopus 로고    scopus 로고
    • Macaque long-term nonprogressors resist superinfection with multiple CD8R T cell escape variants of simian immunodeficiency virus
    • Weinfurter JT, May GE, Soma T, Hessell AJ, Leon EJ, Macnair CE, et al. Macaque long-term nonprogressors resist superinfection with multiple CD8R T cell escape variants of simian immunodeficiency virus. J Virol 2011; 85:530-541.
    • (2011) J Virol , vol.85 , pp. 530-541
    • Weinfurter, J.T.1    May, G.E.2    Soma, T.3    Hessell, A.J.4    Leon, E.J.5    MacNair, C.E.6
  • 100
    • 62749177486 scopus 로고    scopus 로고
    • HLA-B57/BM5801 human immunodeficiency virus type 1 elite controllers select for rare gag variants associated with reduced viral replication capacity and strong cytotoxic T-lymphocyte [corrected] recognition
    • Miura T, Brockman MA, Schneidewind A, Lobritz M, Pereyra F, Rathod A, et al. HLA-B57/BM5801 human immunodeficiency virus type 1 elite controllers select for rare gag variants associated with reduced viral replication capacity and strong cytotoxic T-lymphocyte [corrected] recognition. J Virol 2009; 83:2743-2755.
    • (2009) J Virol , vol.83 , pp. 2743-2755
    • Miura, T.1    Brockman, M.A.2    Schneidewind, A.3    Lobritz, M.4    Pereyra, F.5    Rathod, A.6
  • 105
    • 80052065199 scopus 로고    scopus 로고
    • GagCM9-specific CD8R T cells expressing limited public TCR clonotypes do not suppress SIV replication in vivo
    • Vojnov L, Martins MA, Almeida JR, Ende Z, Rakasz EG, Reynolds MR, et al. GagCM9-specific CD8R T cells expressing limited public TCR clonotypes do not suppress SIV replication in vivo. PLoS One 2011; 6:e23515.
    • (2011) PLoS One , vol.6
    • Vojnov, L.1    Martins, M.A.2    Almeida, J.R.3    Ende, Z.4    Rakasz, E.G.5    Reynolds, M.R.6
  • 106
    • 65549116509 scopus 로고    scopus 로고
    • Public clonotype usage identifies protective Gag-specific CD8R T cell responses in SIV infection
    • Price DA, Asher TE, Wilson NA, Nason MC, Brenchley JM, Metzler IS, et al. Public clonotype usage identifies protective Gag-specific CD8R T cell responses in SIV infection. J Exp Med 2009; 206:923-936.
    • (2009) J Exp Med , vol.206 , pp. 923-936
    • Price, D.A.1    Asher, T.E.2    Wilson, N.A.3    Nason, M.C.4    Brenchley, J.M.5    Metzler, I.S.6
  • 109
    • 79952816254 scopus 로고    scopus 로고
    • Bias in the alphabeta T-cell repertoire: Implications for disease pathogenesis and vaccination
    • Miles JJ, Douek DC, Price DA. Bias in the alphabeta T-cell repertoire: implications for disease pathogenesis and vaccination. Immunol Cell Biol 2011; 89:375-387.
    • (2011) Immunol Cell Biol , vol.89 , pp. 375-387
    • Miles, J.J.1    Douek, D.C.2    Price, D.A.3
  • 110
    • 0036786482 scopus 로고    scopus 로고
    • Effects of cytotoxic T lymphocytes (CTL) directed against a single simian immunodeficiency virus (SIV) Gag CTL epitope on the course of SIVmac239 infection
    • Allen TM, Jing P, Calore B, Horton H, O'Connor DH, Hanke T, et al. Effects of cytotoxic T lymphocytes (CTL) directed against a single simian immunodeficiency virus (SIV) Gag CTL epitope on the course of SIVmac239 infection. J Virol 2002; 76:10507-10511.
    • (2002) J Virol , vol.76 , pp. 10507-10511
    • Allen, T.M.1    Jing, P.2    Calore, B.3    Horton, H.4    O'Connor, D.H.5    Hanke, T.6
  • 113
    • 12344300389 scopus 로고    scopus 로고
    • + T cells from most HIV-1-infected patients, even when challenged with mature dendritic cells, lack functional recall memory to HIV gag but not other viruses
    • DOI 10.1002/eji.200425744
    • Arrode G, Finke JS, Zebroski H, Siegal FP, Steinman RM. CD8R T cells from most HIV-1-infected patients, even when challenged with mature dendritic cells, lack functional recall memory to HIV gag but not other viruses. Eur J Immunol 2005; 35:159-170. (Pubitemid 40123862)
    • (2005) European Journal of Immunology , vol.35 , Issue.1 , pp. 159-170
    • Arrode, G.1    Finke, J.S.2    Zebroski, H.3    Siegal, F.P.4    Steinman, R.M.5
  • 116
    • 77954080011 scopus 로고    scopus 로고
    • Perforin expression directly ex vivo by HIV-specific CD8 T-cells is a correlate of HIV elite control
    • Hersperger AR, Pereyra F, Nason M, Demers K, Sheth P, Shin LY, et al. Perforin expression directly ex vivo by HIV-specific CD8 T-cells is a correlate of HIV elite control. PLoS Pathog 2010; 6:e1000917.
    • (2010) PLoS Pathog , vol.6
    • Hersperger, A.R.1    Pereyra, F.2    Nason, M.3    Demers, K.4    Sheth, P.5    Shin, L.Y.6
  • 117
    • 79551690940 scopus 로고    scopus 로고
    • Interleukin-21-producing HIV-1-specific CD8 T cells are preferentially seen in elite controllers
    • Williams LD, Bansal A, Sabbaj S, Heath SL, Song W, Tang J, et al. Interleukin-21-producing HIV-1-specific CD8 T cells are preferentially seen in elite controllers. J Virol 2011; 85:2316-2324.
    • (2011) J Virol , vol.85 , pp. 2316-2324
    • Williams, L.D.1    Bansal, A.2    Sabbaj, S.3    Heath, S.L.4    Song, W.5    Tang, J.6
  • 119
    • 57449109484 scopus 로고    scopus 로고
    • Lytic granule loading of CD8R T cells is required for HIV-infected cell elimination associated with immune control
    • Migueles SA, Osborne CM, Royce C, Compton AA, Joshi RP, Weeks KA, et al. Lytic granule loading of CD8R T cells is required for HIV-infected cell elimination associated with immune control. Immunity 2008; 29:1009-1021.
    • (2008) Immunity , vol.29 , pp. 1009-1021
    • Migueles, S.A.1    Osborne, C.M.2    Royce, C.3    Compton, A.A.4    Joshi, R.P.5    Weeks, K.A.6
  • 121
    • 77955351656 scopus 로고    scopus 로고
    • Relationship between regulatory T cells and immune activation in human immunodeficiency virus-infected patients interrupting antiretroviral therapy
    • Weiss L, Piketty C, Assoumou L, Didier C, Caccavelli L, Donkova-Petrini V, et al. Relationship between regulatory T cells and immune activation in human immunodeficiency virus-infected patients interrupting antiretroviral therapy. PLoS One 2010; 5:e11659.
    • (2010) PLoS One , vol.5
    • Weiss, L.1    Piketty, C.2    Assoumou, L.3    Didier, C.4    Caccavelli, L.5    Donkova-Petrini, V.6
  • 122
    • 79551649723 scopus 로고    scopus 로고
    • A low T regulatory cell response may contribute to both viral control and generalized immune activation in HIV controllers
    • Hunt PW, Landay AL, Sinclair E, Martinson JA, Hatano H, Emu B, et al. A low T regulatory cell response may contribute to both viral control and generalized immune activation in HIV controllers. PLoS One 2011; 6:e15924.
    • (2011) PLoS One , vol.6
    • Hunt, P.W.1    Landay, A.L.2    Sinclair, E.3    Martinson, J.A.4    Hatano, H.5    Emu, B.6
  • 123
    • 77953748800 scopus 로고    scopus 로고
    • In vivo expansion of naive and activated CD4RCD25RFOXP3R regulatory T cell populations in interleukin-2-treated HIV patients
    • Weiss L, Letimier FA, Carriere M, Maiella S, Donkova-Petrini V, Targat B, et al. In vivo expansion of naive and activated CD4RCD25RFOXP3R regulatory T cell populations in interleukin-2-treated HIV patients. Proc Natl Acad Sci USA 2010; 107:10632-10637.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 10632-10637
    • Weiss, L.1    Letimier, F.A.2    Carriere, M.3    Maiella, S.4    Donkova-Petrini, V.5    Targat, B.6
  • 125
    • 70249122418 scopus 로고    scopus 로고
    • Differential association of programmed death-1 and CD57 with ex vivo survival of CD8R T cells in HIV infection
    • Petrovas C, Chaon B, Ambrozak DR, Price DA, Melenhorst JJ, Hill BJ, et al. Differential association of programmed death-1 and CD57 with ex vivo survival of CD8R T cells in HIV infection. J Immunol 2009; 183:1120-1132.
    • (2009) J Immunol , vol.183 , pp. 1120-1132
    • Petrovas, C.1    Chaon, B.2    Ambrozak, D.R.3    Price, D.A.4    Melenhorst, J.J.5    Hill, B.J.6
  • 128
    • 44449096577 scopus 로고    scopus 로고
    • Antigen load and viral sequence diversification determine the functional profile of HIV-1-specific CD8R T cells
    • Streeck H, Brumme ZL, Anastario M, Cohen KW, Jolin JS, Meier A, et al. Antigen load and viral sequence diversification determine the functional profile of HIV-1-specific CD8R T cells. PLoS Med 2008; 5:e100.
    • (2008) PLoS Med , vol.5
    • Streeck, H.1    Brumme, Z.L.2    Anastario, M.3    Cohen, K.W.4    Jolin, J.S.5    Meier, A.6
  • 129
    • 79955463139 scopus 로고    scopus 로고
    • Understanding animal models of elite control: windowsoneffectiveimmuneresponses againstimmunodeficiency viruses
    • Mudd PA, Watkins DI. Understanding animal models of elite control:windowsoneffectiveimmuneresponses againstimmunodeficiency viruses. Curr Opin HIV AIDS 2011; 6:197-201.
    • (2011) Curr Opin HIV AIDS , vol.6 , pp. 197-201
    • Mudd, P.A.1    Watkins, D.I.2
  • 130
    • 79955476141 scopus 로고    scopus 로고
    • HIV-specific CD4 T cells and immune control of viral replication
    • Porichis F, Kaufmann DE. HIV-specific CD4 T cells and immune control of viral replication. Curr Opin HIV AIDS 2011; 6:174-180.
    • (2011) Curr Opin HIV AIDS , vol.6 , pp. 174-180
    • Porichis, F.1    Kaufmann, D.E.2
  • 132
    • 84862732215 scopus 로고    scopus 로고
    • The design and evaluation of HIV-1 vaccines
    • Saunders KO, Rudicell RS, Nabel GJ. The design and evaluation of HIV-1 vaccines. AIDS 2012; 26:1293-1302.
    • (2012) AIDS , vol.26 , pp. 1293-1302
    • Saunders, K.O.1    Rudicell, R.S.2    Nabel, G.J.3
  • 133
    • 67649213034 scopus 로고    scopus 로고
    • Heterogeneity in HIVsuppression byCD8 T cells from HIV controllers: Association with Gag-specificCD8 T cell responses
    • Saez-Cirion A, Sinet M, Shin SY, Urrutia A, Versmisse P, Lacabaratz C, et al. Heterogeneity in HIVsuppression byCD8 T cells from HIV controllers: association with Gag-specificCD8 T cell responses. J Immunol 2009; 182:7828-7837.
    • (2009) J Immunol , vol.182 , pp. 7828-7837
    • Saez-Cirion, A.1    Sinet, M.2    Shin, S.Y.3    Urrutia, A.4    Versmisse, P.5    Lacabaratz, C.6
  • 137
    • 53749089460 scopus 로고    scopus 로고
    • Gag-specific cytotoxic T-lymphocyte-based control of primary simian immunodeficiency virus replication in a vaccine trial
    • Kawada M, Tsukamoto T, Yamamoto H, Iwamoto N, Kurihara K, Takeda A, et al. Gag-specific cytotoxic T-lymphocyte-based control of primary simian immunodeficiency virus replication in a vaccine trial. J Virol 2008; 82:10199-10206.
    • (2008) J Virol , vol.82 , pp. 10199-10206
    • Kawada, M.1    Tsukamoto, T.2    Yamamoto, H.3    Iwamoto, N.4    Kurihara, K.5    Takeda, A.6
  • 138
    • 77951984813 scopus 로고    scopus 로고
    • Enhanced anti-HIV functional activity associated with Gagspecific CD8 T-cell responses
    • Julg B,WilliamsKL, Reddy S, Bishop K, Qi Y, Carrington M, et al. Enhanced anti-HIV functional activity associated with Gagspecific CD8 T-cell responses. J Virol 2010; 84:5540-5549.
    • (2010) J Virol , vol.84 , pp. 5540-5549
    • Bwilliamskl, J.1    Reddy, S.2    Bishop, K.3    Qi, Y.4    Carrington, M.5
  • 139
    • 0028978720 scopus 로고
    • Gag-specific cytotoxic responses to HIV type 1 are associated with a decreased risk of progression to AIDS-related complex or AIDS
    • Riviere Y, McChesney MB, Porrot F, Tanneau-Salvadori F, Sansonetti P, Lopez O, et al. Gag-specific cytotoxic responses to HIV type 1 are associated with a decreased risk of progression to AIDS-related complex or AIDS. AIDS Res Hum Retroviruses 1995; 11:903-907.
    • (1995) AIDS Res Hum Retroviruses , vol.11 , pp. 903-907
    • Riviere, Y.1    McChesney, M.B.2    Porrot, F.3    Tanneau-Salvadori, F.4    Sansonetti, P.5    Lopez, O.6
  • 141
    • 79958819590 scopus 로고    scopus 로고
    • HIV-specific gag responses in early infancy correlate with clinical outcome and inversely with viral load
    • Nqoko B, Day CL, Mansoor N, De Kock M, Hughes EJ, Hawkridge T, et al. HIV-specific gag responses in early infancy correlate with clinical outcome and inversely with viral load. AIDS Res Hum Retroviruses 2011; 27:1311-1316.
    • (2011) AIDS Res Hum Retroviruses , vol.27 , pp. 1311-1316
    • Nqoko, B.1    Day, C.L.2    Mansoor, N.3    De Kock, M.4    Hughes, E.J.5    Hawkridge, T.6
  • 147
    • 34547115470 scopus 로고    scopus 로고
    • Natural variation in the V3 crown of human immunodeficiency virus type 1 affects replicative fitness and entry inhibitor sensitivity
    • DOI 10.1128/JVI.02739-06
    • Lobritz MA, Marozsan AJ, Troyer RM, Arts EJ. Natural variation in the V3 crown of human immunodeficiency virus type 1 affects replicative fitness and entry inhibitor sensitivity. J Virol 2007; 81:8258-8269. (Pubitemid 47101511)
    • (2007) Journal of Virology , vol.81 , Issue.15 , pp. 8258-8269
    • Lobritz, M.A.1    Marozsan, A.J.2    Troyer, R.M.3    Arts, E.J.4
  • 148
    • 0033803642 scopus 로고    scopus 로고
    • A dual infection/competition assay shows a correlation between ex vivo human immunodeficiency virus type 1 fitness and disease progression
    • Quinones-Mateu ME, Ball SC, Marozsan AJ, Torre VS, Albright JL, Vanham G, et al. A dual infection/competition assay shows a correlation between ex vivo human immunodeficiency virus type 1 fitness and disease progression. J Virol 2000; 74:9222-9233.
    • (2000) J Virol , vol.74 , pp. 9222-9233
    • Quinones-Mateu, M.E.1    Ball, S.C.2    Marozsan, A.J.3    Torre, V.S.4    Albright, J.L.5    Vanham, G.6
  • 149
    • 84857959077 scopus 로고    scopus 로고
    • Variable fitness impact of HIV-1 escape mutations to cytotoxic T lymphocyte (CTL) response
    • Troyer RM, McNevin J, Liu Y, Zhang SC, Krizan RW, Abraha A, et al. Variable fitness impact of HIV-1 escape mutations to cytotoxic T lymphocyte (CTL) response. PLoS Pathog 2009; 5:e1000365.
    • (2009) PLoS Pathog , vol.5
    • Troyer, R.M.1    McNevin, J.2    Liu, Y.3    Zhang, S.C.4    Krizan, R.W.5    Abraha, A.6
  • 151
    • 60049098638 scopus 로고    scopus 로고
    • Expanded breadth of the T-cell response to mosaic human immunodeficiency virus type 1 envelope DNA vaccination
    • Kong WP, Wu L, Wallstrom TC, Fischer W, Yang ZY, Ko SY, et al. Expanded breadth of the T-cell response to mosaic human immunodeficiency virus type 1 envelope DNA vaccination. J Virol 2009; 83:2201-2215.
    • (2009) J Virol , vol.83 , pp. 2201-2215
    • Kong, W.P.1    Wu, L.2    Wallstrom, T.C.3    Fischer, W.4    Yang, Z.Y.5    Ko, S.Y.6
  • 152
    • 77949264937 scopus 로고    scopus 로고
    • Mosaic vaccines elicit CD8R T lymphocyte responses that confer enhanced immune coverage of diverse HIV strains in monkeys
    • Santra S, Liao HX, Zhang R, Muldoon M, Watson S, Fischer W, et al. Mosaic vaccines elicit CD8R T lymphocyte responses that confer enhanced immune coverage of diverse HIV strains in monkeys. Nat Med 2010; 16:324-328.
    • (2010) Nat Med , vol.16 , pp. 324-328
    • Santra, S.1    Liao, H.X.2    Zhang, R.3    Muldoon, M.4    Watson, S.5    Fischer, W.6
  • 153
    • 77949263061 scopus 로고    scopus 로고
    • Mosaic HIV-1 vaccines expand the breadth and depth of cellular immune responses in rhesus monkeys
    • Barouch DH, O'Brien KL, Simmons NL, King SL, Abbink P, Maxfield LF, et al. Mosaic HIV-1 vaccines expand the breadth and depth of cellular immune responses in rhesus monkeys. Nat Med 2010; 16:319-323.
    • (2010) Nat Med , vol.16 , pp. 319-323
    • Barouch, D.H.1    O'Brien, K.L.2    Simmons, N.L.3    King, S.L.4    Abbink, P.5    Maxfield, L.F.6
  • 154
    • 56649105122 scopus 로고    scopus 로고
    • Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the STEP Study): A double-blind, randomised, placebo-controlled, test-of-concept trial
    • Buchbinder SP, Mehrotra DV, Duerr A, Fitzgerald DW, Mogg R, Li D, et al. Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the STEP Study): a double-blind, randomised, placebo-controlled, test-of-concept trial. Lancet 2008; 372:1881-1893.
    • (2008) Lancet , vol.372 , pp. 1881-1893
    • Buchbinder, S.P.1    Mehrotra, D.V.2    Duerr, A.3    Fitzgerald, D.W.4    Mogg, R.5    Li, D.6
  • 155
    • 84862760016 scopus 로고    scopus 로고
    • See http://www.hvtn.org/science/step-buch.html.
    • See
  • 156
    • 56649114351 scopus 로고    scopus 로고
    • HIV-1 vaccine-induced immunity in the test-ofconcept STEP Study: A case-cohort analysis
    • McElrath MJ, De Rosa SC, Moodie Z, Dubey S, Kierstead L, Janes H, et al. HIV-1 vaccine-induced immunity in the test-ofconcept STEP Study: a case-cohort analysis. Lancet 2008; 372:1894-1905.
    • (2008) Lancet , vol.372 , pp. 1894-1905
    • McElrath, M.J.1    De Rosa, S.C.2    Moodie, Z.3    Dubey, S.4    Kierstead, L.5    Janes, H.6
  • 157
    • 79958726847 scopus 로고    scopus 로고
    • Mapping HIV-1 vaccine induced T-cell responses: Bias towards less-conserved regions and potential impact on vaccine efficacy in the STEP study
    • Li F, FinnefrockAC,Dubey SA, KorberBT, Szinger J,Cole S, et al. Mapping HIV-1 vaccine induced T-cell responses: bias towards less-conserved regions and potential impact on vaccine efficacy in the STEP study. PLoS One 2011; 6:e20479.
    • (2011) PLoS One , vol.6
    • Li, F.1    Finnefrockacdubey, S.A.2    Korber, B.T.3    Szinger, J.4    Cole, S.5
  • 158
    • 84855445252 scopus 로고    scopus 로고
    • Human adenovirus-specific T cells modulate HIV-specific T cell responses to an Ad5-vectored HIV-1 vaccine
    • Frahm N, DeCamp AC, Friedrich DP, Carter DK, Defawe OD, Kublin JG, et al. Human adenovirus-specific T cells modulate HIV-specific T cell responses to an Ad5-vectored HIV-1 vaccine. J Clin Invest 2012; 122:359-367.
    • (2012) J Clin Invest , vol.122 , pp. 359-367
    • Frahm, N.1    Decamp, A.C.2    Friedrich, D.P.3    Carter, D.K.4    Defawe, O.D.5    Kublin, J.G.6
  • 159
    • 80051882327 scopus 로고    scopus 로고
    • Tight regulation of memory CD8(R) T cells limits their effectiveness during sustained high viral load
    • West EE, Youngblood B, Tan WG, Jin HT, Araki K, Alexe G, et al. Tight regulation of memory CD8(R) T cells limits their effectiveness during sustained high viral load. Immunity 2011; 35:285-298.
    • (2011) Immunity , vol.35 , pp. 285-298
    • West, E.E.1    Youngblood, B.2    Tan, W.G.3    Jin, H.T.4    Araki, K.5    Alexe, G.6
  • 160
    • 79952324470 scopus 로고    scopus 로고
    • An Ad5-vectored HIV-1 vaccine elicits cellmediated immunity but does not affect disease progression in HIV-1-infected male subjects: Results from a randomized placebo-controlled trial (the STEP study)
    • Fitzgerald DW, Janes H, Robertson M, Coombs R, Frank I, Gilbert P, et al. An Ad5-vectored HIV-1 vaccine elicits cellmediated immunity but does not affect disease progression in HIV-1-infected male subjects: results from a randomized placebo-controlled trial (the STEP study). J Infect Dis 2011; 203:765-772.
    • (2011) J Infect Dis , vol.203 , pp. 765-772
    • Fitzgerald, D.W.1    Janes, H.2    Robertson, M.3    Coombs, R.4    Frank, I.5    Gilbert, P.6
  • 161
  • 162
    • 77954943648 scopus 로고    scopus 로고
    • Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01
    • Zhou T, Georgiev I, Wu X, Yang ZY, Dai K, Finzi A, et al. Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01. Science 2010; 329:811-817.
    • (2010) Science , vol.329 , pp. 811-817
    • Zhou, T.1    Georgiev, I.2    Wu, X.3    Yang, Z.Y.4    Dai, K.5    Finzi, A.6
  • 164
    • 61949216736 scopus 로고    scopus 로고
    • Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge
    • Hansen SG, Vieville C, Whizin N, Coyne-Johnson L, Siess DC, Drummond DD, et al. Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge. Nat Med 2009; 15:293-299.
    • (2009) Nat Med , vol.15 , pp. 293-299
    • Hansen, S.G.1    Vieville, C.2    Whizin, N.3    Coyne-Johnson, L.4    Siess, D.C.5    Drummond, D.D.6
  • 165
  • 166
    • 0842324614 scopus 로고    scopus 로고
    • Jump-starting the immune system: Prime-boosting comes of age
    • DOI 10.1016/j.it.2003.11.009
    • Woodland DL. Jump-starting the immune system: primeboosting comes of age. Trends Immunol 2004; 25:98-104. (Pubitemid 38167491)
    • (2004) Trends in Immunology , vol.25 , Issue.2 , pp. 98-104
    • Woodland, D.L.1
  • 169
    • 0035815437 scopus 로고    scopus 로고
    • Control of a mucosal challenge and prevention of AIDS by a multiprotein DNA/MVA vaccine
    • DOI 10.1126/science.1058915
    • Amara RR, Villinger F, Altman JD, Lydy SL, O'Neil SP, Staprans SI, et al. Control of a mucosal challenge and prevention of AIDS by a multiprotein DNA/MVA vaccine. Science 2001; 292:69-74. (Pubitemid 32289126)
    • (2001) Science , vol.292 , Issue.5514 , pp. 69-74
    • Amara, R.R.1    Villinger, F.2    Altman, J.D.3    Lydy, S.L.4    O'Neil, S.P.5    Staprans, S.I.6
  • 170
    • 77649100110 scopus 로고    scopus 로고
    • Efficacy of multivalent adenovirus-based vaccine against simian immunodeficiency virus challenge
    • Casimiro DR, Cox K, Tang A, Sykes KJ, Feng M, Wang F, et al. Efficacy of multivalent adenovirus-based vaccine against simian immunodeficiency virus challenge. J Virol 2010; 84:2996-3003.
    • (2010) J Virol , vol.84 , pp. 2996-3003
    • Casimiro, D.R.1    Cox, K.2    Tang, A.3    Sykes, K.J.4    Feng, M.5    Wang, F.6
  • 173
    • 67449101823 scopus 로고    scopus 로고
    • Vaccine-induced cellular responses control simian immunodeficiency virus replication after heterologous challenge
    • Wilson NA, Keele BF, Reed JS, Piaskowski SM, MacNair CE, Bett AJ, et al. Vaccine-induced cellular responses control simian immunodeficiency virus replication after heterologous challenge. J Virol 2009; 83:6508-6521.
    • (2009) J Virol , vol.83 , pp. 6508-6521
    • Wilson, N.A.1    Keele, B.F.2    Reed, J.S.3    Piaskowski, S.M.4    MacNair, C.E.5    Bett, A.J.6
  • 174
    • 77956824009 scopus 로고    scopus 로고
    • Low-dose mucosal simian immunodeficiency virus infection restricts early replication kinetics and transmitted virus variants in rhesus monkeys
    • Liu J, Keele BF, Li H, Keating S, Norris PJ, Carville A, et al. Low-dose mucosal simian immunodeficiency virus infection restricts early replication kinetics and transmitted virus variants in rhesus monkeys. J Virol 2010; 84:10406-10412.
    • (2010) J Virol , vol.84 , pp. 10406-10412
    • Liu, J.1    Keele, B.F.2    Li, H.3    Keating, S.4    Norris, P.J.5    Carville, A.6
  • 175
  • 176
    • 1542287436 scopus 로고    scopus 로고
    • Repeated Low-Dose Mucosal Simian Immunodeficiency Virus SIVmac239 Challenge Results in the Same Viral and Immunological Kinetics as High-Dose Challenge: A Model for the Evaluation of Vaccine Efficacy in Nonhuman Primates
    • DOI 10.1128/JVI.78.6.3140-3144.2004
    • McDermott AB, Mitchen J, Piaskowski S, De Souza I, Yant LJ, Stephany J, et al. Repeated low-dose mucosal simian immunodeficiency virus SIVmac239 challenge results in the same viral and immunological kinetics as high-dose challenge: a model for the evaluation of vaccine efficacy in nonhuman primates. J Virol 2004; 78:3140-3144. (Pubitemid 38314372)
    • (2004) Journal of Virology , vol.78 , Issue.6 , pp. 3140-3144
    • McDermott, A.B.1    Mitchen, J.2    Piaskowski, S.3    De Souza, I.4    Yant, L.J.5    Stephany, J.6    Furlott, J.7    Watkins, D.I.8
  • 177
    • 80052436008 scopus 로고    scopus 로고
    • Enhanced control of pathogenic Simian immunodeficiency virus SIVmac239 replication in macaques immunized with an interleukin-12 plasmid and a DNA primeviral vector boost vaccine regimen
    • Winstone N, Wilson AJ, Morrow G, Boggiano C, Chiuchiolo MJ, Lopez M, et al. Enhanced control of pathogenic Simian immunodeficiency virus SIVmac239 replication in macaques immunized with an interleukin-12 plasmid and a DNA primeviral vector boost vaccine regimen. J Virol 2011; 85:9578-9587.
    • (2011) J Virol , vol.85 , pp. 9578-9587
    • Winstone, N.1    Wilson, A.J.2    Morrow, G.3    Boggiano, C.4    Chiuchiolo, M.J.5    Lopez, M.6
  • 178
    • 58149267963 scopus 로고    scopus 로고
    • Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys
    • Liu J, O'Brien KL, Lynch DM, Simmons NL, La Porte A, Riggs AM, et al. Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys. Nature 2009; 457:87-91.
    • (2009) Nature , vol.457 , pp. 87-91
    • Liu, J.1    O'Brien, K.L.2    Lynch, D.M.3    Simmons, N.L.4    La Porte, A.5    Riggs, A.M.6
  • 179
    • 84856482137 scopus 로고    scopus 로고
    • Vaccine protection against acquisition of neutralizationresistant SIV challenges in rhesus monkeys
    • Barouch DH, Liu J, Li H, Maxfield LF, Abbink P, Lynch DM, et al. Vaccine protection against acquisition of neutralizationresistant SIV challenges in rhesus monkeys. Nature 2012; 482:89-93.
    • (2012) Nature , vol.482 , pp. 89-93
    • Barouch, D.H.1    Liu, J.2    Li, H.3    Maxfield, L.F.4    Abbink, P.5    Lynch, D.M.6
  • 181
    • 84855913888 scopus 로고    scopus 로고
    • New paradigms for HIV/AIDS vaccine development
    • Picker LJ, Hansen SG, Lifson JD. New paradigms for HIV/AIDS vaccine development. Annu Rev Med 2012; 63:95-111.
    • (2012) Annu Rev Med , vol.63 , pp. 95-111
    • Picker, L.J.1    Hansen, S.G.2    Lifson, J.D.3


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