HLA-B57/B *5801 human immunodeficiency virus type 1 elite controllers select for rare gag variants associated with reduced viral replication capacity and strong cytotoxic T-lymphotye recognition

Journal of Virology

Volumn 83, Issue 6, 2009, Pages 2743-2755

  Miura, Toshiyuki ^a,b,c   Brockman, Mark A ^a,c   Schneidewind, Arne ^a,c   Lobritz, Michael ^d   Pereyra, Florencia ^a,c   Rathod, Almas ^a   Block, Brian L ^a   Brumme, Zabrina L ^a,c   Brumme, Chanson J ^a   Baker, Brett ^a   Rothchild, Alissa C ^a   Li, Bin ^a,c   Trocha, Alicja ^a,b   Cutrell, Emily ^a   Frahm, Nicole ^a,c   Brander, Christian ^a,c   Toth, Ildiko ^a   Arts, Eric J ^d   Allen, Todd M ^a,c   Walker, Bruce D ^a,b,c  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; EPITOPE; GAG PROTEIN; GAMMA INTERFERON; HLA B57 ANTIGEN; HLA B ANTIGEN; HLA B*5801 ANTIGEN, HUMAN; HLA-B*5801 ANTIGEN, HUMAN; HLA-B57;

ALLELE; ANTIGEN RECOGNITION; ARTICLE; CD8+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; ENZYME LINKED IMMUNOSPOT ASSAY; GENE MUTATION; GENE SEQUENCE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; IMMUNE RESPONSE; IN VITRO STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN VARIANT; VIREMIA; VIRUS MUTANT; VIRUS REPLICATION; AMINO ACID SUBSTITUTION; DNA SEQUENCE; GENETICS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOLOGY; MISSENSE MUTATION; MOLECULAR GENETICS; PHYLOGENY; PHYSIOLOGY; VIROLOGY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

AMINO ACID SUBSTITUTION; EPITOPES, T-LYMPHOCYTE; HIV INFECTIONS; HIV-1; HLA-B ANTIGENS; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; PHYLOGENY; SEQUENCE ANALYSIS, DNA; VIRUS REPLICATION;

EID: 62749177486     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.02265-08     Document Type: Article

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