Human leukocyte antigen-specific polymorphisms in HIV-1 Gag and their association with viral load in chronic untreated infection

AIDS

Volumn 22, Issue 11, 2008, Pages 1277-1286

  Brumme, Zabrina L ^a   Tao, Iris ^b   Szeto, Sharon ^b   Brumme, Chanson J ^a   Carlson, Jonathan M ^c,d   Chan, Dennison ^b   Kadie, Carl ^c   Frahm, Nicole ^a   Brander, Christian ^a   Walker, Bruce ^a,e   Heckerman, David ^c   Harrigan, P Richard ^b,f  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b BRITISH COLUMBIA CENTRE FOR EXCELLENCE IN HIV AIDS   (Canada)

^c MICROSOFT RESEARCH   (United States)

^d University of Washington   (United States)

^e HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^f UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Cytotoxic T lymphocyte escape; HIV 1; Human leukocyte antigen class I; Plasma viral load; Viral evolution

Indexed keywords

ANTIRETROVIRUS AGENT; EPITOPE; GAG PROTEIN; HLA ANTIGEN CLASS 1; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; LEUKOCYTE ANTIGEN; VIRUS VACCINE;

ADAPTATION; ARTICLE; CHRONIC DISEASE; CLINICAL ASSESSMENT; CODON; CORRELATION COEFFICIENT; CROSS-SECTIONAL STUDY; CYTOTOXIC T LYMPHOCYTE; DISEASE MARKER; GENE LINKAGE DISEQUILIBRIUM; GENE MAPPING; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; MAJOR CLINICAL STUDY; MUTATION; NUCLEOTIDE SEQUENCE; PHYLOGENY; PRIORITY JOURNAL; PROTEIN POLYMORPHISM; T LYMPHOCYTE; VIREMIA; VIRUS LOAD; AMINO ACID SEQUENCE; CD4 LYMPHOCYTE COUNT; GENE; GENETIC POLYMORPHISM; GENETICS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOLOGY; MOLECULAR GENETICS; VIROLOGY;

AMINO ACID SEQUENCE; CD4 LYMPHOCYTE COUNT; CHRONIC DISEASE; CROSS-SECTIONAL STUDIES; GAG GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; GENES, MHC CLASS I; HIV INFECTIONS; HIV-1; HUMANS; MOLECULAR SEQUENCE DATA; POLYMORPHISM, GENETIC; T-LYMPHOCYTES, CYTOTOXIC; VIRAL LOAD;

EID: 49849087657     PISSN: 02699370     EISSN: 14735571     Source Type: Journal    
DOI: 10.1097/QAD.0b013e3283021a8c     Document Type: Article

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