Viral CTL escape mutants are generated in lymph nodes and subsequently become fixed in plasma and rectal mucosa during acute SIV infection of macaques

PLoS Pathogens

Volumn 7, Issue 5, 2011, Pages

  Vanderford, Thomas H ^a,b   Bleckwehl, Chelsea ^b   Engram, Jessica C ^b   Dunham, Richard M ^b   Klatt, Nichole R ^b   Feinberg, Mark B ^c   Garber, David A ^a   Betts, Michael R ^b   Silvestri, Guido ^a,b  

^a EMORY UNIVERSITY   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; LYMPH NODE; MACACA; MUTANT; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; RECTUM BIOPSY; RECTUM MUCOSA; SIMIAN IMMUNODEFICIENCY VIRUS INFECTION; VIRUS INFECTION; VIRUS REPLICATION; ANIMAL; BLOOD; GENETICS; IMMUNOLOGY; INTESTINE MUCOSA; MACACA MULATTA; MOLECULAR GENETICS; PHYSIOLOGY; RECTUM; REGULATOR GENE; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; STRUCTURAL GENE; VIROLOGY;

MACACA; MACACA MULATTA; SIMIAN IMMUNODEFICIENCY VIRUS;

ANIMALS; GENES, GAG; GENES, TAT; IMMUNODOMINANT EPITOPES; INTESTINAL MUCOSA; LYMPH NODES; MACACA MULATTA; MOLECULAR SEQUENCE DATA; RECTUM; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; T-LYMPHOCYTES, CYTOTOXIC; VIRUS REPLICATION;

EID: 79958030663     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002048     Document Type: Article

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