MDA5 and PTPN2, two candidate genes for type 1 diabetes, modify pancreatic β-cell responses to the viral by-product double-stranded RNA

Human Molecular Genetics

Volumn 19, Issue 1, 2009, Pages 135-146

  Colli, Maikel L ^a   Moore, Fabrice ^a   Gurzov, Esteban N ^a   Ortis, Fernanda ^a   Eizirik, Decio L ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CYTOKINE; DOUBLE STRANDED RNA; MESSENGER RNA; NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE 2; POLYINOSINIC POLYCYTIDYLIC ACID; PROTEIN MDA5; RETINOIC ACID INDUCIBLE PROTEIN I; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; BETA INTERFERON; DEAD BOX PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PTPN2 PROTEIN, RAT; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION; GENETIC SELECTION; GENETIC TRANSFECTION; INSULIN DEPENDENT DIABETES MELLITUS; KNOCKOUT GENE; MALE; MICROARRAY ANALYSIS; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN TARGETING; RAT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; VIRUS INFECTION; VIRUS REPLICATION; WESTERN BLOTTING; ANIMAL; DRUG EFFECT; ENZYME ACTIVATION; ENZYMOLOGY; GENETICS; METABOLISM; PATHOLOGY; PROMOTER REGION; SECRETION; VIRUS; WISTAR RAT;

RATTUS;

ANIMALS; APOPTOSIS; CHEMOKINES; DEAD-BOX RNA HELICASES; DIABETES MELLITUS, TYPE 1; ENZYME ACTIVATION; INSULIN-SECRETING CELLS; INTERFERON-BETA; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; NF-KAPPA B; POLY I-C; PROMOTER REGIONS, GENETIC; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 2; RATS; RATS, WISTAR; RNA, DOUBLE-STRANDED; RNA, SMALL INTERFERING; VIRUSES;

EID: 77649326700     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddp474     Document Type: Article

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