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Volumn 17, Issue 3, 2012, Pages 449-473

Angiogenic therapy for cardiac repair based on protein delivery systems

Author keywords

Angiogenesis; Cardiac repair; Cardiovascular diseases; Growth factor; Protein delivery

Indexed keywords

ALGINIC ACID; ANGIOPOIETIN; ANGIOPOIETIN 1; ANGIOPOIETIN 2; ERYTHROPOIETIN; FIBRIN; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 1; FIBROBLAST GROWTH FACTOR 2; GRANULOCYTE COLONY STIMULATING FACTOR; GROWTH FACTOR; HYALURONIC ACID; KERATINOCYTE GROWTH FACTOR; MACROGOL; MOLECULAR SCAFFOLD; NANOPARTICLE; NEU DIFFERENTIATION FACTOR; PLACEBO; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR BB; POLYMER; RECOMBINANT PROTEIN; SCATTER FACTOR; SITAGLIPTIN; SOMATOMEDIN C; SONIC HEDGEHOG PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UNINDEXED DRUG; VASCULOTROPIN; VASCULOTROPIN A;

EID: 84862539591     PISSN: 13824147     EISSN: 15737322     Source Type: Journal    
DOI: 10.1007/s10741-011-9285-8     Document Type: Review
Times cited : (49)

References (215)
  • 1
    • 77954144091 scopus 로고    scopus 로고
    • WHO, Last visited March 2011
    • WHO (2008) WHO The global burden of disease: 2004 update. http://www.who.int/entity/healthinfo/global-burden-disease/GBD-report- 2004update-full.pdf. Last visited March 2011
    • (2008) WHO The Global Burden of Disease: 2004 Update
  • 3
    • 45449089213 scopus 로고    scopus 로고
    • Atlas of heart disease and stroke
    • World Health Organization
    • Mackay J, Mensah G (2004) Atlas of heart disease and stroke. World Health Organization, Geneva
    • (2004) Geneva
    • MacKay, J.1    Mensah, G.2
  • 5
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman J (1971) Tumor angiogenesis: therapeutic implications. N Engl J Med 285 (21):1182-1186
    • (1971) N Engl J Med , vol.285 , Issue.21 , pp. 1182-1186
    • Folkman, J.1
  • 7
    • 0021359304 scopus 로고
    • Heparin affinity: Purification of a tumorderived capillary endothelial cell growth factor
    • Shing Y, Folkman J, Sullivan R, Butterfield C, Murray J, Klagsbrun M (1984) Heparin affinity: purification of a tumorderived capillary endothelial cell growth factor. Science 223 (4642):1296-1299
    • (1984) Science , vol.223 , Issue.4642 , pp. 1296-1299
    • Shing, Y.1    Folkman, J.2    Sullivan, R.3    Butterfield, C.4    Murray, J.5    Klagsbrun, M.6
  • 8
    • 0000491207 scopus 로고
    • Primary structure of bovine pituitary basic fibroblast growth factor (FGF) and comparison with the amino-terminal sequence of bovine brain acidic FGF
    • Esch F, Baird A, Ling N, Ueno N, Hill F, Denoroy L, Klepper R, Gospodarowicz D, Bohlen P, Guillemin R (1985) Primary structure of bovine pituitary basic fibroblast growth factor (FGF) and comparison with the amino-terminal sequence of bovine brain acidic FGF. Proc Natl Acad Sci USA 82 (19):6507-6511
    • (1985) Proc Natl Acad Sci USA , vol.82 , Issue.19 , pp. 6507-6511
    • Esch, F.1    Baird, A.2    Ling, N.3    Ueno, N.4    Hill, F.5    Denoroy, L.6    Klepper, R.7    Gospodarowicz, D.8    Bohlen, P.9    Guillemin, R.10
  • 10
    • 2642565248 scopus 로고    scopus 로고
    • Therapeutic angiogenesis and vasculogenesis for ischemic disease
    • Losordo DW, Dimmeler S (2004) Therapeutic angiogenesis and vasculogenesis for ischemic disease. Part I: angiogenic cytokines. Circulation 109 (21):2487-2491
    • (2004) Part I: Angiogenic Cytokines. Circulation , vol.109 , Issue.21 , pp. 2487-2491
    • Losordo, D.W.1    Dimmeler, S.2
  • 12
    • 0033886323 scopus 로고    scopus 로고
    • Fibroblast growth factor-1 stimulates branching and survival of myocardial arteries: A goal for therapeutic angiogenesis?
    • Carmeliet P (2000) Fibroblast growth factor-1 stimulates branching and survival of myocardial arteries: a goal for therapeutic angiogenesis? Circ Res 87 (3):176-178
    • (2000) Circ Res , vol.87 , Issue.3 , pp. 176-178
    • Carmeliet, P.1
  • 13
    • 0041440927 scopus 로고    scopus 로고
    • Fibroblast growth factor-2 (FGF-2) induces vascular endothelial growth factor (VEGF) expression in the endothelial cells of forming capillaries: An autocrine mechanism contributing to angiogenesis
    • Seghezzi G, Patel S, Ren CJ, Gualandris A, Pintucci G, Robbins ES, Shapiro RL, Galloway AC, Rifkin DB, Mignatti P (1998) Fibroblast growth factor-2 (FGF-2) induces vascular endothelial growth factor (VEGF) expression in the endothelial cells of forming capillaries: an autocrine mechanism contributing to angiogenesis. J Cell Biol 141 (7):1659-1673
    • (1998) J Cell Biol , vol.141 , Issue.7 , pp. 1659-1673
    • Seghezzi, G.1    Patel, S.2    Ren, C.J.3    Gualandris, A.4    Pintucci, G.5    Robbins, E.S.6    Shapiro, R.L.7    Galloway, A.C.8    Rifkin, D.B.9    Mignatti, P.10
  • 14
    • 0035136140 scopus 로고    scopus 로고
    • Fibroblast growth factor 2 activation of stromal cell vascular endothelial growth factor expression and angiogenesis
    • Claffey KP, Abrams K, Shih SC, Brown LF, Mullen A, Keough M (2001) Fibroblast growth factor 2 activation of stromal cell vascular endothelial growth factor expression and angiogenesis. Lab Invest 81 (1):61-75
    • (2001) Lab Invest , vol.81 , Issue.1 , pp. 61-75
    • Claffey, K.P.1    Abrams, K.2    Shih, S.C.3    Brown, L.F.4    Mullen, A.5    Keough, M.6
  • 15
    • 24944534593 scopus 로고    scopus 로고
    • VEGF-A and FGF-2 synergistically promote neoangiogenesis through enhancement of endogenous PDGF-B-PDGFRbeta signaling
    • Kano MR, Morishita Y, Iwata C, Iwasaka S, Watabe T, Ouchi Y, Miyazono K, Miyazawa K (2005) VEGF-A and FGF-2 synergistically promote neoangiogenesis through enhancement of endogenous PDGF-B-PDGFRbeta signaling. J Cell Sci 118 (Pt 16):3759-3768
    • (2005) J Cell Sci , vol.118 PART 16 , pp. 3759-3768
    • Kano, M.R.1    Morishita, Y.2    Iwata, C.3    Iwasaka, S.4    Watabe, T.5    Ouchi, Y.6    Miyazono, K.7    Miyazawa, K.8
  • 17
    • 0024384470 scopus 로고
    • Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells
    • Ferrara N, Henzel WJ (1989) Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells. Biochem Biophys Res Commun 161:851-858
    • (1989) Biochem Biophys Res Commun , vol.161 , pp. 851-858
    • Ferrara, N.1    Henzel, W.J.2
  • 21
  • 22
    • 0035956947 scopus 로고    scopus 로고
    • Predominant role of endothelial nitric oxide synthase in vascular endothelial growth factor-induced angiogenesis and vascular permeability
    • Fukumura D, Gohongi T, Kadambi A, Izumi Y, Ang J, Yun CO, Buerk DG, Huang PL, Jain RK (2001) Predominant role of endothelial nitric oxide synthase in vascular endothelial growth factor-induced angiogenesis and vascular permeability. Proc Natl Acad Sci USA 98 (5):2604-2609
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.5 , pp. 2604-2609
    • Fukumura, D.1    Gohongi, T.2    Kadambi, A.3    Izumi, Y.4    Ang, J.5    Yun, C.O.6    Buerk, D.G.7    Huang, P.L.8    Jain, R.K.9
  • 23
    • 0033522927 scopus 로고    scopus 로고
    • Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchoragedependent manner
    • Fujio Y, Walsh K (1999) Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchoragedependent manner. J Biol Chem 274 (23):16349-16354
    • (1999) J Biol Chem , vol.274 , Issue.23 , pp. 16349-16354
    • Fujio, Y.1    Walsh, K.2
  • 24
    • 0035355472 scopus 로고    scopus 로고
    • A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells
    • Takahashi T, Yamaguchi S, Chida K, Shibuya M (2001) A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells. EMBO J 20 (11):2768-2778
    • (2001) EMBO J , vol.20 , Issue.11 , pp. 2768-2778
    • Takahashi, T.1    Yamaguchi, S.2    Chida, K.3    Shibuya, M.4
  • 25
    • 0032541165 scopus 로고    scopus 로고
    • Chemotactic properties of angiopoietin-1 and - 2, ligands for the endothelial-specific receptor tyrosine kinase Tie2
    • Witzenbichler B, Maisonpierre PC, Jones P, Yancopoulos GD, Isner JM (1998) Chemotactic properties of angiopoietin-1 and - 2, ligands for the endothelial-specific receptor tyrosine kinase Tie2. J Biol Chem 273 (29):18514-18521
    • (1998) J Biol Chem , vol.273 , Issue.29 , pp. 18514-18521
    • Witzenbichler, B.1    Maisonpierre, P.C.2    Jones, P.3    Yancopoulos, G.D.4    Isner, J.M.5
  • 26
  • 28
    • 33344477298 scopus 로고    scopus 로고
    • Tie receptors and their angiopoietin ligands are context-dependent regulators of vascular remodeling
    • Eklund L, Olsen BR (2006) Tie receptors and their angiopoietin ligands are context-dependent regulators of vascular remodeling. Exp Cell Res 312 (5):630-641
    • (2006) Exp Cell Res , vol.312 , Issue.5 , pp. 630-641
    • Eklund, L.1    Olsen, B.R.2
  • 31
    • 0032985888 scopus 로고    scopus 로고
    • Hypoxia and vascular endothelial growth factor selectively up-regulate angiopoietin-2 in bovine microvascular endothelial cells
    • Oh H, Takagi H, Suzuma K, Otani A, Matsumura M, Honda Y (1999) Hypoxia and vascular endothelial growth factor selectively up-regulate angiopoietin-2 in bovine microvascular endothelial cells. J Biol Chem 274 (22):15732-15739
    • (1999) J Biol Chem , vol.274 , Issue.22 , pp. 15732-15739
    • Oh, H.1    Takagi, H.2    Suzuma, K.3    Otani, A.4    Matsumura, M.5    Honda, Y.6
  • 34
    • 2942682933 scopus 로고    scopus 로고
    • Insight into the physiological functions of PDGF through genetic studies in mice
    • Betsholtz C (2004) Insight into the physiological functions of PDGF through genetic studies in mice. Cytokine Growth Factor Rev 15 (4):215-228
    • (2004) Cytokine Growth Factor Rev , vol.15 , Issue.4 , pp. 215-228
    • Betsholtz, C.1
  • 35
    • 0038363443 scopus 로고    scopus 로고
    • Angiogenic synergism, vascular stability and improvement of hind-limb ischemia by a combination of PDGF-BB and FGF-2
    • Cao R, Brakenhielm E, Pawliuk R, Wariaro D, Post MJ, Wahlberg E, Leboulch P, Cao Y (2003) Angiogenic synergism, vascular stability and improvement of hind-limb ischemia by a combination of PDGF-BB and FGF-2. Nat Med 9 (5):604-613
    • (2003) Nat Med , vol.9 , Issue.5 , pp. 604-613
    • Cao, R.1    Brakenhielm, E.2    Pawliuk, R.3    Wariaro, D.4    Post, M.J.5    Wahlberg, E.6    Leboulch, P.7    Cao, Y.8
  • 37
    • 58249114895 scopus 로고    scopus 로고
    • Differential roles of PDGFR-alpha and PDGFR-beta in angiogenesis and vessel stability
    • Zhang J, Cao R, Zhang Y, Jia T, Cao Y, Wahlberg E (2009) Differential roles of PDGFR-alpha and PDGFR-beta in angiogenesis and vessel stability. FASEB J 23 (1):153-163
    • (2009) FASEB J , vol.23 , Issue.1 , pp. 153-163
    • Zhang, J.1    Cao, R.2    Zhang, Y.3    Jia, T.4    Cao, Y.5    Wahlberg, E.6
  • 40
    • 34247863773 scopus 로고    scopus 로고
    • The neuregulin-I/ErbB signaling system in development and disease
    • Britsch S (2007) The neuregulin-I/ErbB signaling system in development and disease. Adv Anat Embryol Cell Biol 190:1-65
    • (2007) Adv Anat Embryol Cell Biol , vol.190 , pp. 1-65
    • Britsch, S.1
  • 42
    • 10944236872 scopus 로고    scopus 로고
    • Cardiac endothelial cells regulate reactive oxygen species-induced cardiomyocyte apoptosis through neuregulin- 1beta/erbB4 signaling
    • Kuramochi Y, Cote GM, Guo X, Lebrasseur NK, Cui L, Liao R, Sawyer DB (2004) Cardiac endothelial cells regulate reactive oxygen species-induced cardiomyocyte apoptosis through neuregulin- 1beta/erbB4 signaling. J Biol Chem 279 (49):51141-51147
    • (2004) J Biol Chem , vol.279 , Issue.49 , pp. 51141-51147
    • Kuramochi, Y.1    Cote, G.M.2    Guo, X.3    Lebrasseur, N.K.4    Cui, L.5    Liao, R.6    Sawyer, D.B.7
  • 43
    • 0032562770 scopus 로고    scopus 로고
    • Neuregulins promote survival and growth of cardiac myocytes. Persistence of ErbB2 and ErbB4 expression in neonatal and adult ventricular myocytes
    • Zhao YY, Sawyer DR, Baliga RR, Opel DJ, Han X, Marchionni MA, Kelly RA (1998) Neuregulins promote survival and growth of cardiac myocytes. Persistence of ErbB2 and ErbB4 expression in neonatal and adult ventricular myocytes. J Biol Chem 273 (17):10261-10269
    • (1998) J Biol Chem , vol.273 , Issue.17 , pp. 10261-10269
    • Zhao, Y.Y.1    Sawyer, D.R.2    Baliga, R.R.3    Opel, D.J.4    Han, X.5    Marchionni, M.A.6    Kelly, R.A.7
  • 44
    • 0344924865 scopus 로고    scopus 로고
    • Neuregulin-1 protects ventricular myocytes from anthracycline-induced apoptosis via erbB4-dependent activation of PI3-kinase/Akt
    • Fukazawa R, Miller TA, Kuramochi Y, Frantz S, Kim YD, Marchionni MA, Kelly RA, Sawyer DB (2003) Neuregulin-1 protects ventricular myocytes from anthracycline-induced apoptosis via erbB4-dependent activation of PI3-kinase/Akt. J Mol Cell Cardiol 35 (12):1473-1479
    • (2003) J Mol Cell Cardiol , vol.35 , Issue.12 , pp. 1473-1479
    • Fukazawa, R.1    Miller, T.A.2    Kuramochi, Y.3    Frantz, S.4    Kim, Y.D.5    Marchionni, M.A.6    Kelly, R.A.7    Sawyer, D.B.8
  • 45
    • 4043110498 scopus 로고    scopus 로고
    • Neuregulins regulate cardiac parasympathetic activity: Muscarinic modulation of beta-adrenergic activity in myocytes from mice with neuregulin-1 gene deletion
    • Okoshi K, Nakayama M, Yan X, Okoshi MP, Schuldt AJ, Marchionni MA, Lorell BH (2004) Neuregulins regulate cardiac parasympathetic activity: muscarinic modulation of beta-adrenergic activity in myocytes from mice with neuregulin-1 gene deletion. Circulation 110 (6):713-717
    • (2004) Circulation , vol.110 , Issue.6 , pp. 713-717
    • Okoshi, K.1    Nakayama, M.2    Yan, X.3    Okoshi, M.P.4    Schuldt, A.J.5    Marchionni, M.A.6    Lorell, B.H.7
  • 46
    • 67650569135 scopus 로고    scopus 로고
    • Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury
    • Bersell K, Arab S, Haring B, Kuhn B (2009) Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury. Cell 138 (2):257-270
    • (2009) Cell , vol.138 , Issue.2 , pp. 257-270
    • Bersell, K.1    Arab, S.2    Haring, B.3    Kuhn, B.4
  • 48
    • 77957357286 scopus 로고    scopus 로고
    • Neuregulin-1/ErbB signaling and chronic heart failure
    • Xu Y, Li X, Liu X, Zhou M (2010) Neuregulin-1/ErbB signaling and chronic heart failure. Adv Pharmacol 59:31-51
    • (2010) Adv Pharmacol , vol.59 , pp. 31-51
    • Xu, Y.1    Li, X.2    Liu, X.3    Zhou, M.4
  • 49
    • 1642458136 scopus 로고    scopus 로고
    • Neuregulin-1 induces a negative inotropic effect in cardiac muscle: Role of nitric oxide synthase
    • Lemmens K, Fransen P, Sys SU, Brutsaert DL, De Keulenaer GW (2004) Neuregulin-1 induces a negative inotropic effect in cardiac muscle: role of nitric oxide synthase. Circulation 109 (3): 324-326
    • (2004) Circulation , vol.109 , Issue.3 , pp. 324-326
    • Lemmens, K.1    Fransen, P.2    Sys, S.U.3    Brutsaert, D.L.4    De Keulenaer, G.W.5
  • 52
    • 77952317892 scopus 로고    scopus 로고
    • A Phase II, randomized, doubleblind, multicenter, based on standard therapy, placebo-controlled study of the efficacy and safety of recombinant human neuregulin-1 in patients with chronic heart failure
    • Gao R, Zhang J, Cheng L, Wu X, Dong W, Yang X, Li T, Liu X, Xu Y, Li X, Zhou M (2010) A Phase II, randomized, doubleblind, multicenter, based on standard therapy, placebo-controlled study of the efficacy and safety of recombinant human neuregulin-1 in patients with chronic heart failure. J Am Coll Cardiol 55 (18):1907-1914
    • (2010) J Am Coll Cardiol , vol.55 , Issue.18 , pp. 1907-1914
    • Gao, R.1    Zhang, J.2    Cheng, L.3    Wu, X.4    Dong, W.5    Yang, X.6    Li, T.7    Liu, X.8    Xu, Y.9    Li, X.10    Zhou, M.11
  • 53
    • 0019133661 scopus 로고
    • Mutations affecting segment number and polarity in Drosophila
    • Nusslein-Volhard C, Wieschaus E (1980) Mutations affecting segment number and polarity in Drosophila. Nature 287 (5785): 795-801
    • (1980) Nature , vol.287 , Issue.5785 , pp. 795-801
    • Nusslein-Volhard, C.1    Wieschaus, E.2
  • 54
    • 0027760995 scopus 로고
    • Sonic hedgehog mediates the polarizing activity of the ZPA
    • Riddle RD, Johnson RL, Laufer E, Tabin C (1993) Sonic hedgehog mediates the polarizing activity of the ZPA. Cell 75 (7):1401-1416
    • (1993) Cell , vol.75 , Issue.7 , pp. 1401-1416
    • Riddle, R.D.1    Johnson, R.L.2    Laufer, E.3    Tabin, C.4
  • 55
    • 0027756145 scopus 로고
    • Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity
    • Echelard Y, Epstein DJ, St-Jacques B, Shen L, Mohler J, McMahon JA, McMahon AP (1993) Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity. Cell 75 (7):1417-1430
    • (1993) Cell , vol.75 , Issue.7 , pp. 1417-1430
    • Echelard, Y.1    Epstein, D.J.2    St-Jacques, B.3    Shen, L.4    Mohler, J.5    McMahon, J.A.6    McMahon, A.P.7
  • 56
    • 0027749249 scopus 로고
    • A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos
    • Krauss S, Concordet JP, Ingham PW (1993) A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos. Cell 75 (7):1431-1444
    • (1993) Cell , vol.75 , Issue.7 , pp. 1431-1444
    • Krauss, S.1    Concordet, J.P.2    Ingham, P.W.3
  • 57
    • 0142153787 scopus 로고    scopus 로고
    • The hedgehog signaling network
    • Cohen MM Jr (2003) The hedgehog signaling network. Am J Med Genet A 123A (1):5-28
    • (2003) Am J Med Genet A 123A , vol.1 , pp. 5-28
    • Cohen Jr., M.M.1
  • 58
    • 77956269175 scopus 로고    scopus 로고
    • Frequent deregulations in the hedgehog signaling network and cross-talks with the epidermal growth factor receptor pathway involved in cancer progression and targeted therapies
    • Mimeault M, Batra SK (2010) Frequent deregulations in the hedgehog signaling network and cross-talks with the epidermal growth factor receptor pathway involved in cancer progression and targeted therapies. Pharmacol Rev 62 (3):497-524
    • (2010) Pharmacol Rev , vol.62 , Issue.3 , pp. 497-524
    • Mimeault, M.1    Batra, S.K.2
  • 59
    • 42049104913 scopus 로고    scopus 로고
    • The adventures of sonic hedgehog in development and repair. III. Hedgehog processing and biological activity
    • Farzan SF, Singh S, Schilling NS, Robbins DJ (2008) The adventures of sonic hedgehog in development and repair. III. Hedgehog processing and biological activity. Am J Physiol Gastrointest Liver Physiol 294 (4):G844-G849
    • (2008) Am J Physiol Gastrointest Liver Physiol , vol.294 , Issue.4
    • Farzan, S.F.1    Singh, S.2    Schilling, N.S.3    Robbins, D.J.4
  • 61
    • 30644469247 scopus 로고    scopus 로고
    • Release and trafficking of lipid-linked morphogens
    • Eaton S (2006) Release and trafficking of lipid-linked morphogens. Curr Opin Genet Dev 16 (1):17-22
    • (2006) Curr Opin Genet Dev , vol.16 , Issue.1 , pp. 17-22
    • Eaton, S.1
  • 62
    • 34948864401 scopus 로고    scopus 로고
    • Sonic hedgehog induces transcription-independent cytoskeletal rearrangement and migration regulated by arachidonate metabolites
    • Bijlsma MF, Borensztajn KS, Roelink H, Peppelenbosch MP, Spek CA (2007) Sonic hedgehog induces transcription-independent cytoskeletal rearrangement and migration regulated by arachidonate metabolites. Cell Signal 19 (12):2596-2604
    • (2007) Cell Signal , vol.19 , Issue.12 , pp. 2596-2604
    • Bijlsma, M.F.1    Borensztajn, K.S.2    Roelink, H.3    Peppelenbosch, M.P.4    Spek, C.A.5
  • 63
    • 77951932085 scopus 로고    scopus 로고
    • Hedgehog proteins activate pro-angiogenic responses in endothelial cells through non-canonical signaling pathways
    • Chinchilla P, Xiao L, Kazanietz MG, Riobo NA (2010) Hedgehog proteins activate pro-angiogenic responses in endothelial cells through non-canonical signaling pathways. Cell Cycle 9 (3):570-579
    • (2010) Cell Cycle , vol.9 , Issue.3 , pp. 570-579
    • Chinchilla, P.1    Xiao, L.2    Kazanietz, M.G.3    Riobo, N.A.4
  • 64
    • 46849087764 scopus 로고    scopus 로고
    • Hedgehog signaling is critical for maintenance of the adult coronary vasculature in mice
    • Lavine KJ, Kovacs A, Ornitz DM (2008) Hedgehog signaling is critical for maintenance of the adult coronary vasculature in mice. J Clin Invest 118 (7):2404-2414
    • (2008) J Clin Invest , vol.118 , Issue.7 , pp. 2404-2414
    • Lavine, K.J.1    Kovacs, A.2    Ornitz, D.M.3
  • 67
    • 77958555989 scopus 로고    scopus 로고
    • Microparticles carrying Sonic hedgehog favor neovascularization through the activation of nitric oxide pathway in mice
    • Benameur T, Soleti R, Porro C, Andriantsitohaina R, Martinez MC (2010) Microparticles carrying Sonic hedgehog favor neovascularization through the activation of nitric oxide pathway in mice. PloS One 5 (9):e12688
    • (2010) PloS One , vol.5 , Issue.9
    • Benameur, T.1    Soleti, R.2    Porro, C.3    Andriantsitohaina, R.4    Martinez, M.C.5
  • 70
    • 77649161196 scopus 로고    scopus 로고
    • Sonic Hedgehog gene delivery to the rodent heart promotes angiogenesis via iNOS/netrin-1/PKC pathway
    • AhmedRP, HaiderKH, Shujia J,AfzalMR,AshrafM (2010) Sonic Hedgehog gene delivery to the rodent heart promotes angiogenesis via iNOS/netrin-1/PKC pathway. PloS One 5 (1):e8576
    • (2010) PloS One , vol.5 , Issue.1
    • Haiderkh, A.1    Jafzalmrashrafm, S.2
  • 73
    • 0032562232 scopus 로고    scopus 로고
    • Induction of neoangiogenesis in ischemic myocardium by human growth factors First clinical results of a new treatment of coronary heart disease
    • Schumacher B, Pecher P, von Specht BU, Stegmann T (1998) Induction of neoangiogenesis in ischemic myocardium by human growth factors. First clinical results of a new treatment of coronary heart disease. Circulation 97:645-650
    • (1998) Circulation , vol.97 , pp. 645-650
    • Schumacher, B.1    Pecher, P.2    Von Specht, B.U.3    Stegmann, T.4
  • 74
    • 18344417427 scopus 로고    scopus 로고
    • Effects of a single intracoronary injection of basic fibroblast growth factor in stable angina pectoris
    • Unger EF et al (2000) Effects of a single intracoronary injection of basic fibroblast growth factor in stable angina pectoris. Am J Cardiol 85:1414-1419
    • (2000) Am J Cardiol , vol.85 , pp. 1414-1419
    • Unger, E.F.1
  • 77
    • 4243780765 scopus 로고    scopus 로고
    • Magnitude and location of new angiographically apparent coronary collaterals following intravenous VEGF administration
    • 65A (Abstract
    • Gibson C, Laham R, Giordano F (1999) Magnitude and location of new angiographically apparent coronary collaterals following intravenous VEGF administration. J Am Coll Cardiol 33 (Suppl. A):65A (Abstract)
    • (1999) J Am Coll Cardiol , vol.33 SUPPL. A
    • Gibson, C.1    Laham, R.2    Giordano, F.3
  • 78
    • 0033982580 scopus 로고    scopus 로고
    • Effect of intracoronary recombinant human vascular endothelial growth factor on myocardial perfusion: Evidence for a dose-dependent effect
    • Hendel RC, Henry TD, Rocha-Singh K, Isner JM, Kereiakes DJ, Giordano FJ, Simons M, Bonow RO (2000) Effect of intracoronary recombinant human vascular endothelial growth factor on myocardial perfusion: evidence for a dose-dependent effect. Circulation 101:118-121
    • (2000) Circulation , vol.101 , pp. 118-121
    • Hendel, R.C.1    Henry, T.D.2    Rocha-Singh, K.3    Isner, J.M.4    Kereiakes, D.J.5    Giordano, F.J.6    Simons, M.7    Bonow, R.O.8
  • 79
    • 0034750066 scopus 로고    scopus 로고
    • Results of intracoronary recombinant human vascular endothelial growth factor (rhVEGF) administration trial
    • Henry TD, Rocha-Singh K, Isner JM et al (2001) Results of intracoronary recombinant human vascular endothelial growth factor (rhVEGF) administration trial. Am Heart J 142:872-880
    • (2001) Am Heart J , vol.142 , pp. 872-880
    • Henry, T.D.1    Rocha-Singh, K.2    Isner, J.M.3
  • 81
    • 70349754505 scopus 로고    scopus 로고
    • Myocardial salvage through coronary collateral growth by granulocyte colonystimulating factor in chronic coronary artery disease: A controlled randomized trial
    • Meier P, Gloekler S, de Marchi SF, Indermuehle A, Rutz T, Traupe T, Steck H, Vogel R, Seiler C (2009) Myocardial salvage through coronary collateral growth by granulocyte colonystimulating factor in chronic coronary artery disease: a controlled randomized trial. Circulation 120 (14):1355-1363
    • (2009) Circulation , vol.120 , Issue.14 , pp. 1355-1363
    • Meier, P.1    Gloekler, S.2    De Marchi, S.F.3    Indermuehle, A.4    Rutz, T.5    Traupe, T.6    Steck, H.7    Vogel, R.8    Seiler, C.9
  • 84
    • 78650023641 scopus 로고    scopus 로고
    • Safety and efficacy of SITAgliptin plus GRanulocyte-colony-stimulating factor in patients suffering from acute myocardial infarction (SITAGRAMI-trial)-rationale, design and first interim analysis
    • Theiss HD, Brenner C, Engelmann MG, Zaruba MM, Huber B, Henschel V, Mansmann U, Wintersperger B, Reiser M, Steinbeck G, Franz WM (2010) Safety and efficacy of SITAgliptin plus GRanulocyte-colony-stimulating factor in patients suffering from acute myocardial infarction (SITAGRAMI-trial)-rationale, design and first interim analysis. Int J Cardiol 145 (2):282-284
    • (2010) Int J Cardiol , vol.145 , Issue.2 , pp. 282-284
    • Theiss, H.D.1    Brenner, C.2    Engelmann, M.G.3    Zaruba, M.M.4    Huber, B.5    Henschel, V.6    Mansmann, U.7    Wintersperger, B.8    Reiser, M.9    Steinbeck, G.10    Franz, W.M.11
  • 85
    • 67649980246 scopus 로고    scopus 로고
    • Effect of hepatocyte growth-promoting factors on myocardial ischemia during exercise in patients with severe coronary artery disease
    • Wang N, Tong G, Yang J, Zhou Z, Pan H, Huo Y, Xu J, Zhang X, Ling F, Li P (2009) Effect of hepatocyte growth-promoting factors on myocardial ischemia during exercise in patients with severe coronary artery disease. Int Heart J 50 (3):291-299
    • (2009) Int Heart J , vol.50 , Issue.3 , pp. 291-299
    • Wang, N.1    Tong, G.2    Yang, J.3    Zhou, Z.4    Pan, H.5    Huo, Y.6    Xu, J.7    Zhang, X.8    Ling, F.9    Li, P.10
  • 86
    • 70549097146 scopus 로고    scopus 로고
    • Effects of recombinant human erythropoietin on platelet activation in acute myocardial infarction: Results of a doubleblind, placebo-controlled, randomized trial
    • Tang YD, Hasan F, Giordano FJ, Pfau S, Rinder HM, Katz SD (2009) Effects of recombinant human erythropoietin on platelet activation in acute myocardial infarction: results of a doubleblind, placebo-controlled, randomized trial. Am Heart J 158 (6): 941-947
    • (2009) Am Heart J , vol.158 , Issue.6 , pp. 941-947
    • Tang, Y.D.1    Hasan, F.2    Giordano, F.J.3    Pfau, S.4    Rinder, H.M.5    Katz, S.D.6
  • 88
    • 36549022091 scopus 로고    scopus 로고
    • Combating cardiovascular disease with angiogenic therapy
    • Jacobs J (2007) Combating cardiovascular disease with angiogenic therapy. Drug Discov Today 12 (23-24):1040-1045
    • (2007) Drug Discov Today , vol.12 , Issue.23-24 , pp. 1040-1045
    • Jacobs, J.1
  • 90
    • 0035858370 scopus 로고    scopus 로고
    • Development of poly- (D, L-lactide-coglycolide) microsphere formulations containing recombinant human vascular endothelial growth factor to promote local angiogenesis
    • Cleland JL, Duenas ET, Park A, Daugherty A, Kahn J, Kowalski J, Cuthbertson A (2001) Development of poly- (D, L-lactide-coglycolide) microsphere formulations containing recombinant human vascular endothelial growth factor to promote local angiogenesis. J Control Release 72:13-24
    • (2001) J Control Release , vol.72 , pp. 13-24
    • Cleland, J.L.1    Duenas, E.T.2    Park, A.3    Daugherty, A.4    Kahn, J.5    Kowalski, J.6    Cuthbertson, A.7
  • 91
    • 84920069370 scopus 로고    scopus 로고
    • Clinical vascular growth factor therapy for neovascularization in patients with coronary artery disease
    • Kupatt C (eds Therapeutic neovascularization-quo vadis? Springer, Dordrecht
    • Kastrup J (2007) Clinical vascular growth factor therapy for neovascularization in patients with coronary artery disease. In: Deindl E, Kupatt C (eds) Therapeutic neovascularization-quo vadis?. Springer, Dordrecht, pp 1-22
    • (2007) Deindl e , pp. 1-22
    • Kastrup, J.1
  • 92
    • 0034601738 scopus 로고    scopus 로고
    • Therapeutic angiogenesis with recombinant fibroblast growth factor-2 improves stress and rest myocardial perfusion abnormalities in patients with severe chronic coronary artery disease
    • Udelson JE, Dilsizian V, Laham RJ, Chronos N, Vansant J, Blais M, Galt JR, Pike M, Yoshizawa C, Simons M (2000) Therapeutic angiogenesis with recombinant fibroblast growth factor-2 improves stress and rest myocardial perfusion abnormalities in patients with severe chronic coronary artery disease. Circulation 102:1605-1610
    • (2000) Circulation , vol.102 , pp. 1605-1610
    • Udelson, J.E.1    Dilsizian, V.2    Laham, R.J.3    Chronos, N.4    Vansant, J.5    Blais, M.6    Galt, J.R.7    Pike, M.8    Yoshizawa, C.9    Simons, M.10
  • 93
    • 0033034205 scopus 로고    scopus 로고
    • Intracoronary and intravenous administration of basic fibroblast growth factor: Myocardial and tissue distribution
    • Laham RJ, Rezaee M, Post M, Sellke FW, Braeckman RA, Hung D, Simons M (1999) Intracoronary and intravenous administration of basic fibroblast growth factor: myocardial and tissue distribution. Drug Metab Dispos 27 (7):821-826
    • (1999) Drug Metab Dispos , vol.27 , Issue.7 , pp. 821-826
    • Laham, R.J.1    Rezaee, M.2    Post, M.3    Sellke, F.W.4    Braeckman, R.A.5    Hung, D.6    Simons, M.7
  • 94
    • 0030117109 scopus 로고    scopus 로고
    • Basic fibroblast growth factor for stimulation of bone formation in osteoinductive or conductive implants
    • Wang JS (1996) Basic fibroblast growth factor for stimulation of bone formation in osteoinductive or conductive implants. Acta Orthop Scand Suppl 269:1-33
    • (1996) Acta Orthop Scand Suppl , vol.269 , pp. 1-33
    • Wang, J.S.1
  • 95
    • 0035895777 scopus 로고    scopus 로고
    • Therapeutic angiogenesis in cardiology using protein formulations
    • Post MJ, Laham RJ, Sellke FW, Simons M (2001) Therapeutic angiogenesis in cardiology using protein formulations. Cardiovasc Res 49:522-531
    • (2001) Cardiovasc Res , vol.49 , pp. 522-531
    • Post, M.J.1    Laham, R.J.2    Sellke, F.W.3    Simons, M.4
  • 96
    • 80054730594 scopus 로고    scopus 로고
    • Preformulation research: Assessing protein solution behavior during early development
    • Jameel F, Hershenson S (eds Formulation and process development strategies for manufacturing biopharmaceuticals Wiley
    • Pérez-Ramirez B, Guziewicz N, Simler R (2010) Preformulation research: assessing protein solution behavior during early development. In: Jameel F, Hershenson S (eds) Formulation and process development strategies for manufacturing biopharmaceuticals. Wiley, Hoboken
    • (2010) Hoboken
    • Pérez-Ramirez, B.1    Guziewicz, N.2    Simler, R.3
  • 97
    • 0022032982 scopus 로고
    • The stabilization of proteins by osmolytes
    • Arakawa T, Timasheff SN (1985) The stabilization of proteins by osmolytes. Biophys J 47 (3):411-414
    • (1985) Biophys J , vol.47 , Issue.3 , pp. 411-414
    • Arakawa, T.1    Timasheff, S.N.2
  • 98
    • 0027729733 scopus 로고
    • The development of stable protein formulations: A close look at protein aggregation, deamidation, and oxidation
    • Cleland JL, Powell MF, Shire SJ (1993) The development of stable protein formulations: a close look at protein aggregation, deamidation, and oxidation. Crit Rev Ther Drug Carrier Syst 10 (4):307-377
    • (1993) Crit Rev Ther Drug Carrier Syst , vol.10 , Issue.4 , pp. 307-377
    • Cleland, J.L.1    Powell, M.F.2    Shire, S.J.3
  • 99
    • 4143136640 scopus 로고    scopus 로고
    • Vascular endothelial growth factor: Basic science and clinical progress
    • Ferrara N (2004) Vascular endothelial growth factor: basic science and clinical progress. Endocr Rev 25:581-611
    • (2004) Endocr Rev , vol.25 , pp. 581-611
    • Ferrara, N.1
  • 100
    • 0037699954 scopus 로고    scopus 로고
    • The biology of VEGF and its receptors
    • Ferrara N, Gerber HP, LeCouter J (2003) The biology of VEGF and its receptors. Nat Med 9:669-676
    • (2003) Nat Med , vol.9 , pp. 669-676
    • Ferrara, N.1    Gerber, H.P.2    Lecouter, J.3
  • 101
    • 0033793881 scopus 로고    scopus 로고
    • VEGF gene therapy: Stimulating angiogenesis or angioma-genesis?
    • Carmeliet P (2000) VEGF gene therapy: stimulating angiogenesis or angioma-genesis? Nat Med 6 (10):1102-1103
    • (2000) Nat Med , vol.6 , Issue.10 , pp. 1102-1103
    • Carmeliet, P.1
  • 102
    • 33845548437 scopus 로고    scopus 로고
    • Perspectives on: Local and sustained delivery of angiogenic growth factors
    • Lee H, Chung HJ, Park TG (2007) Perspectives on: local and sustained delivery of angiogenic growth factors. J Bioact Compat Polym 22:89-114
    • (2007) J Bioact Compat Polym , vol.22 , pp. 89-114
    • Lee, H.1    Chung, H.J.2    Park, T.G.3
  • 103
    • 34250805948 scopus 로고    scopus 로고
    • Polymeric protein delivery systems
    • Lee KY, Yuk SH (2007) Polymeric protein delivery systems. Progr Polymer Sci 32 (7):669-697
    • (2007) Progr Polymer Sci , vol.32 , Issue.7 , pp. 669-697
    • Lee, K.Y.1    Yuk, S.H.2
  • 104
    • 0033646579 scopus 로고    scopus 로고
    • Controlled release of vascular endothelial growth factor by use of collagen hydrogels
    • Tabata Y, Miyao M, Ozeki M, Ikada Y (2000) Controlled release of vascular endothelial growth factor by use of collagen hydrogels. J Biomater Sci Polym Ed 11 (9):915-930
    • (2000) J Biomater Sci Polym Ed , vol.11 , Issue.9 , pp. 915-930
    • Tabata, Y.1    Miyao, M.2    Ozeki, M.3    Ikada, Y.4
  • 105
    • 0037049981 scopus 로고    scopus 로고
    • Myocardial gene therapy
    • Isner JM (2002) Myocardial gene therapy. Nature 415:234-239
    • (2002) Nature , vol.415 , pp. 234-239
    • Isner, J.M.1
  • 106
    • 51649106996 scopus 로고    scopus 로고
    • In vitro and in vivo release of vascular endothelial growth factor from gelatin microparticles and biodegradable composite scaffolds
    • Patel ZS, Ueda H, Yamamoto M, Tabata Y, Mikos AG (2008) In vitro and in vivo release of vascular endothelial growth factor from gelatin microparticles and biodegradable composite scaffolds. Pharm Res 25 (10):2370-2378
    • (2008) Pharm Res , vol.25 , Issue.10 , pp. 2370-2378
    • Patel, Z.S.1    Ueda, H.2    Yamamoto, M.3    Tabata, Y.4    Mikos, A.G.5
  • 107
    • 0035895767 scopus 로고    scopus 로고
    • Therapeutic interventions for enhancing collateral development by administration of growth factors: Basic principles, early results and potential hazards
    • Epstein SE, Fuchs S, Zhou YF, Baffour R, Kornowski R (2001) Therapeutic interventions for enhancing collateral development by administration of growth factors: basic principles, early results and potential hazards. Cardiovasc Res 49:532-542
    • (2001) Cardiovasc Res , vol.49 , pp. 532-542
    • Epstein, S.E.1    Fuchs, S.2    Zhou, Y.F.3    Baffour, R.4    Kornowski, R.5
  • 113
    • 20444412662 scopus 로고    scopus 로고
    • Injectable glycosaminoglycan hydrogels for controlled release of human basic fibroblast growth factor
    • Cai SS, Liu YC, Shu XZ, Prestwich GD (2005) Injectable glycosaminoglycan hydrogels for controlled release of human basic fibroblast growth factor. Biomaterials 26:6054-6067
    • (2005) Biomaterials , vol.26 , pp. 6054-6067
    • Cai, S.S.1    Liu, Y.C.2    Shu, X.Z.3    Prestwich, G.D.4
  • 114
    • 0035405650 scopus 로고    scopus 로고
    • Extensive in vivo angiogenesis following controlled release of human vascular endothelial cell growth factor: Implications for tissue engineering and wound healing
    • Elcin YM, Dixit V, Gitnick T (2001) Extensive in vivo angiogenesis following controlled release of human vascular endothelial cell growth factor: Implications for tissue engineering and wound healing. Artif Organs 25 (7):558-565
    • (2001) Artif Organs , vol.25 , Issue.7 , pp. 558-565
    • Elcin, Y.M.1    Dixit, V.2    Gitnick, T.3
  • 115
    • 2142662103 scopus 로고    scopus 로고
    • Sustained delivery of vascular endothelial growth factor with alginate beads
    • Gu F, Amsden B, Neufeld R (2004) Sustained delivery of vascular endothelial growth factor with alginate beads. J Control Release 96 (3):463-472
    • (2004) J Control Release , vol.96 , Issue.3 , pp. 463-472
    • Gu, F.1    Amsden, B.2    Neufeld, R.3
  • 116
    • 59049107306 scopus 로고    scopus 로고
    • Controlled delivery of VEGF via modulation of alginate microparticle ionic crosslinking
    • Jay SM, Saltzman WM (2009) Controlled delivery of VEGF via modulation of alginate microparticle ionic crosslinking. J Control Release 134:26-34
    • (2009) J Control Release , vol.134 , pp. 26-34
    • Jay, S.M.1    Saltzman, W.M.2
  • 118
    • 34547159184 scopus 로고    scopus 로고
    • Controlled release of vascular endothelial growth factor from alginate hydrogels nano-coated with polyelectrolyte multilayer films
    • Matsusaki M, Sakaguchi H, Serizawa T, Akashi M (2007) Controlled release of vascular endothelial growth factor from alginate hydrogels nano-coated with polyelectrolyte multilayer films. J Biomater Sci Polym Ed 18 (6):775-783
    • (2007) J Biomater Sci Polym Ed , vol.18 , Issue.6 , pp. 775-783
    • Matsusaki, M.1    Sakaguchi, H.2    Serizawa, T.3    Akashi, M.4
  • 119
    • 34247610438 scopus 로고    scopus 로고
    • Spatiotemporal control of vascular endothelial growth factor delivery from injectable hydrogels enhances angiogenesis
    • Silva EA, Mooney DJ (2007) Spatiotemporal control of vascular endothelial growth factor delivery from injectable hydrogels enhances angiogenesis. J Thromb Haemost 5:590-598
    • (2007) J Thromb Haemost , vol.5 , pp. 590-598
    • Silva, E.A.1    Mooney, D.J.2
  • 120
    • 0242551681 scopus 로고    scopus 로고
    • Biopolymeric delivery matrices for angiogenic growth factors
    • Zisch AH, Lutolf MP, Hubbell JA (2003) Biopolymeric delivery matrices for angiogenic growth factors. Cardiovasc Pathol 12:295-310
    • (2003) Cardiovasc Pathol , vol.12 , pp. 295-310
    • Zisch, A.H.1    Lutolf, M.P.2    Hubbell, J.A.3
  • 122
    • 0037409924 scopus 로고    scopus 로고
    • Implantable applications of chitin and chitosan
    • Khor E, Lim LY (2003) Implantable applications of chitin and chitosan. Biomaterials 24 (13):2339-2349
    • (2003) Biomaterials , vol.24 , Issue.13 , pp. 2339-2349
    • Khor, E.1    Lim, L.Y.2
  • 124
    • 77955709587 scopus 로고    scopus 로고
    • Improved myocardial performance in infarcted rat heart by co-injection of basic fibroblast growth factor with temperature-responsive chitosan hydrogel
    • Wang H, Zhang X, Li Y, Ma Y, Zhang Y, Liu Z, Zhou J, Lin Q, Wang Y, Duan C, Wang C (2010) Improved myocardial performance in infarcted rat heart by co-injection of basic fibroblast growth factor with temperature-responsive chitosan hydrogel. J Heart Lung Transplant 29 (8):881-887
    • (2010) J Heart Lung Transplant , vol.29 , Issue.8 , pp. 881-887
    • Wang, H.1    Zhang, X.2    Li, Y.3    Ma, Y.4    Zhang, Y.5    Liu, Z.6    Zhou, J.7    Lin, Q.8    Wang, Y.9    Duan, C.10    Wang, C.11
  • 125
    • 0034609628 scopus 로고    scopus 로고
    • Development and in vitro characterization of vascular endothelial growth factor (VEGF)-loaded poly (DL-lactic-co-glycolic acid)/poly (ethylene glycol) microspheres using a solid encapsulation/single emulsion/solvent extraction technique
    • King TW, Patrick CW (2000) Development and in vitro characterization of vascular endothelial growth factor (VEGF)-loaded poly (DL-lactic-co-glycolic acid)/poly (ethylene glycol) microspheres using a solid encapsulation/single emulsion/solvent extraction technique. J Biomed Mater Res 51 (3):383-390
    • (2000) J Biomed Mater Res , vol.51 , Issue.3 , pp. 383-390
    • King, T.W.1    Patrick, C.W.2
  • 126
    • 33846489090 scopus 로고    scopus 로고
    • Concurrent delivery of dexamethasone and VEGF for localized inflammation control and angiogenesis
    • Patil SD, Papadmitrakopoulos F, Burgess DJ (2007) Concurrent delivery of dexamethasone and VEGF for localized inflammation control and angiogenesis. J Control Release 117 (1):68-79
    • (2007) J Control Release , vol.117 , Issue.1 , pp. 68-79
    • Patil, S.D.1    Papadmitrakopoulos, F.2    Burgess, D.J.3
  • 127
  • 129
  • 131
    • 33746038183 scopus 로고    scopus 로고
    • PEG-crosslinked heparin is an affinity hydrogel for sustained release of vascular endothelial growth factor
    • Tae G, Scatena M, Stayton PS, Hoffman AS (2006) PEG-crosslinked heparin is an affinity hydrogel for sustained release of vascular endothelial growth factor. J Biomater Sci Polym Ed 17 (1-2):187-197
    • (2006) J Biomater Sci Polym Ed , vol.17 , Issue.1-2 , pp. 187-197
    • Tae, G.1    Scatena, M.2    Stayton, P.S.3    Hoffman, A.S.4
  • 132
    • 20444412662 scopus 로고    scopus 로고
    • Injectable glycosaminoglycan hydrogels for controlled release of human basic fibroblast growth factor
    • Cai SS, Liu YC, Shu XZ, Prestwich GD (2005) Injectable glycosaminoglycan hydrogels for controlled release of human basic fibroblast growth factor. Biomaterials 26 (30):6054-6067
    • (2005) Biomaterials , vol.26 , Issue.30 , pp. 6054-6067
    • Cai, S.S.1    Liu, Y.C.2    Shu, X.Z.3    Prestwich, G.D.4
  • 136
    • 28844448256 scopus 로고    scopus 로고
    • Novel functional biodegradable polymer IV: PHsensitive controlled release of fibroblast growth factor-2 from a poly (c-glutamic acid)-sulfonate matrix for tissue engineering
    • Matsusaki M, Akashi M (2005) Novel functional biodegradable polymer IV: pHsensitive controlled release of fibroblast growth factor-2 from a poly (c-glutamic acid)-sulfonate matrix for tissue engineering. Biomacromolecules 6:3351-3356
    • (2005) Biomacromolecules , vol.6 , pp. 3351-3356
    • Matsusaki, M.1    Akashi, M.2
  • 137
    • 33847654322 scopus 로고    scopus 로고
    • The effect of the controlled release of basic fibroblast growth factor from ionic gelatin-based hydrogels on angiogenesis in a murine critical limb ischemic model
    • Layman H, Spiga MG, Brooks T, Pham S, Webster KA, Andreopoulos FM (2007) The effect of the controlled release of basic fibroblast growth factor from ionic gelatin-based hydrogels on angiogenesis in a murine critical limb ischemic model. Biomaterials 28 (16):2646-2654
    • (2007) Biomaterials , vol.28 , Issue.16 , pp. 2646-2654
    • Layman, H.1    Spiga, M.G.2    Brooks, T.3    Pham, S.4    Webster, K.A.5    Andreopoulos, F.M.6
  • 139
    • 78751700969 scopus 로고    scopus 로고
    • Delivery of basic fibroblast growth factor with a pH-responsive, injectable hydrogel to improve angiogenesis in infarcted myocardium
    • Garbern JC, Minami E, Stayton PS, Murry CE (2011) Delivery of basic fibroblast growth factor with a pH-responsive, injectable hydrogel to improve angiogenesis in infarcted myocardium. Biomaterials 32 (9):2407-2416
    • (2011) Biomaterials , vol.32 , Issue.9 , pp. 2407-2416
    • Garbern, J.C.1    Minami, E.2    Stayton, P.S.3    Murry, C.E.4
  • 140
    • 33750298315 scopus 로고    scopus 로고
    • FGF1/p38 MAP kinase inhibitor therapy induces cardiomyocyte mitosis, reduces scarring, and rescues function after myocardial infarction
    • Engel FB, Hsieh PC, Lee RT, Keating MT (2006) FGF1/p38 MAP kinase inhibitor therapy induces cardiomyocyte mitosis, reduces scarring, and rescues function after myocardial infarction. Proc Natl Acad Sci USA 103 (42):15546-15551
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.42 , pp. 15546-15551
    • Engel, F.B.1    Hsieh, P.C.2    Lee, R.T.3    Keating, M.T.4
  • 141
    • 0029827477 scopus 로고    scopus 로고
    • Angiogenesis induced by acidic fibroblast growth factor as an alternative method of revascularization for chronic myocardial ischemia
    • Sellke FW, Li J, Stamler A, Lopez JJ, Thomas KA, Simons M (1996) Angiogenesis induced by acidic fibroblast growth factor as an alternative method of revascularization for chronic myocardial ischemia. Surgery 120 (2):182-188
    • (1996) Surgery , vol.120 , Issue.2 , pp. 182-188
    • Sellke, F.W.1    Li, J.2    Stamler, A.3    Lopez, J.J.4    Thomas, K.A.5    Simons, M.6
  • 142
    • 0037499581 scopus 로고    scopus 로고
    • Intramyocardial sustained delivery of basic fibroblast growth factor improves angiogenesis and ventricular function in a rat infarct model
    • Iwakura A, Fujita M, Kataoka K, Tambara K, Sakakibara Y, Komeda M, Tabata Y (2003) Intramyocardial sustained delivery of basic fibroblast growth factor improves angiogenesis and ventricular function in a rat infarct model. Heart Vessels 18 (2):93-99
    • (2003) Heart Vessels , vol.18 , Issue.2 , pp. 93-99
    • Iwakura, A.1    Fujita, M.2    Kataoka, K.3    Tambara, K.4    Sakakibara, Y.5    Komeda, M.6    Tabata, Y.7
  • 143
    • 33645364686 scopus 로고    scopus 로고
    • Effects of intramyocardial administration of slow-release basic fibroblast growth factor on angiogenesis and ventricular remodeling in a rat infarct model
    • Shao ZQ, Takaji K, Katayama Y, Kunitomo R, Sakaguchi H, Lai ZF, Kawasuji M (2006) Effects of intramyocardial administration of slow-release basic fibroblast growth factor on angiogenesis and ventricular remodeling in a rat infarct model. Circ J 70:471-477
    • (2006) Circ J , vol.70 , pp. 471-477
    • Shao, Z.Q.1    Takaji, K.2    Katayama, Y.3    Kunitomo, R.4    Sakaguchi, H.5    Lai, Z.F.6    Kawasuji, M.7
  • 146
    • 65349110432 scopus 로고    scopus 로고
    • Collagen-targeting vascular endothelial growth factor improves cardiac performance after myocardial infarction
    • Zhang J, Ding L, Zhao Y, Sun W, Chen B, Lin H, Wang X, Zhang L, Xu B, Dai J (2009) Collagen-targeting vascular endothelial growth factor improves cardiac performance after myocardial infarction. Circulation 119:1776-1784
    • (2009) Circulation , vol.119 , pp. 1776-1784
    • Zhang, J.1    Ding, L.2    Zhao, Y.3    Sun, W.4    Chen, B.5    Lin, H.6    Wang, X.7    Zhang, L.8    Xu, B.9    Dai, J.10
  • 147
    • 78449256874 scopus 로고    scopus 로고
    • Infarct stabilization and cardiac repair with a VEGFconjugated, injectable hydrogel
    • Wu J, Zeng F, Huang XP, Chung JC, Konecny F, Weisel RD, Li RK (2011) Infarct stabilization and cardiac repair with a VEGFconjugated, injectable hydrogel. Biomaterials 32 (2):579-586
    • (2011) Biomaterials , vol.32 , Issue.2 , pp. 579-586
    • Wu, J.1    Zeng, F.2    Huang, X.P.3    Chung, J.C.4    Konecny, F.5    Weisel, R.D.6    Li, R.K.7
  • 148
    • 77955428420 scopus 로고    scopus 로고
    • Temperature-induced gel formation of core/shell nanoparticles for the regeneration of ischemic heart
    • Oh KS, Song JY, Yoon SJ, Park Y, Kim D, Yuk SH (2010) Temperature-induced gel formation of core/shell nanoparticles for the regeneration of ischemic
    • (2010) J Control Release , vol.146 , Issue.2 , pp. 207-211
    • Oh, K.S.1    Song, J.Y.2    Yoon, S.J.3    Park, Y.4    Kim, D.5    Yuk, S.H.6
  • 149
    • 67649834505 scopus 로고    scopus 로고
    • The inhibition of postinfarct ventricle remodeling without polycythaemia following local sustained intramyocardial delivery of erythropoietin within a supramolecular hydrogel
    • Wang T, Jiang XJ, Lin T, Ren S, Li XY, Zhang XZ, Tang QZ (2009) The inhibition of postinfarct ventricle remodeling without polycythaemia following local sustained intramyocardial delivery of erythropoietin within a supramolecular hydrogel. Biomaterials 30 (25):4161-4167
    • (2009) Biomaterials , vol.30 , Issue.25 , pp. 4161-4167
    • Wang, T.1    Jiang, X.J.2    Lin, T.3    Ren, S.4    Li, X.Y.5    Zhang, X.Z.6    Tang, Q.Z.7
  • 151
    • 0035385135 scopus 로고    scopus 로고
    • Hydrogels for tissue engineering
    • Lee KY, Mooney DJ (2001) Hydrogels for tissue engineering. Chem Rev 101:1869-1879
    • (2001) Chem Rev , vol.101 , pp. 1869-1879
    • Lee, K.Y.1    Mooney, D.J.2
  • 152
    • 0028111654 scopus 로고
    • Enhanced vascularization and tissue granulation by basic fibroblast growth factor impregnated in gelatin hydrogels
    • Tabata Y, Hijikata S, Ikada Y (1994) Enhanced vascularization and tissue granulation by basic fibroblast growth factor impregnated in gelatin hydrogels. J Control Release 31:189-199
    • (1994) J Control Release , vol.31 , pp. 189-199
    • Tabata, Y.1    Hijikata, S.2    Ikada, Y.3
  • 153
    • 84862509855 scopus 로고    scopus 로고
    • NF 26 Port City Press, Baltimore
    • Pharmacopeia U (2008) USP 31, NF 26. Port City Press, Baltimore
    • (2008) USP , vol.31
    • Pharmacopeia, U.1
  • 155
    • 77956482606 scopus 로고    scopus 로고
    • Photocrosslinkable chitosan modified with angiopoietin-1 peptide, QHREDGS, promotes survival of neonatal rat heart cells
    • Rask F, Dallabrida SM, Ismail NS, Amoozgar Z, Yeo Y, Rupnick MA, Radisic M (2010) Photocrosslinkable chitosan modified with angiopoietin-1 peptide, QHREDGS, promotes survival of neonatal rat heart cells. J Biomed Mater Res A 95 (1):105-117
    • (2010) J Biomed Mater Res A , vol.95 , Issue.1 , pp. 105-117
    • Rask, F.1    Dallabrida, S.M.2    Ismail, N.S.3    Amoozgar, Z.4    Yeo, Y.5    Rupnick, M.A.6    Radisic, M.7
  • 158
    • 21744459416 scopus 로고    scopus 로고
    • Control of basic fibroblast growth factor release from fibrin gel with heparin and concentrations of fibrinogen and thrombin
    • Jeon O, Ryu SH, Chung JH, Kim BS (2005) Control of basic fibroblast growth factor release from fibrin gel with heparin and concentrations of fibrinogen and thrombin. J Control Release 105 (3):249-259
    • (2005) J Control Release , vol.105 , Issue.3 , pp. 249-259
    • Jeon, O.1    Ryu, S.H.2    Chung, J.H.3    Kim, B.S.4
  • 162
    • 78349308470 scopus 로고    scopus 로고
    • Functional neovascularization of biodegradable dextran hydrogels with multiple angiogenic growth factors
    • Sun G, Shen YI, Kusuma S, Fox-Talbot K, JS C, Gerecht S (2011) Functional neovascularization of biodegradable dextran hydrogels with multiple angiogenic growth factors. Biomaterials 32 (1):95-106
    • (2011) Biomaterials , vol.32 , Issue.1 , pp. 95-106
    • Sun, G.1    Shen, Y.I.2    Kusuma, S.3    Fox-Talbot, K.4    S, C.J.5    Gerecht, S.6
  • 163
    • 21444455526 scopus 로고    scopus 로고
    • Controlled release of EGF and bFGF from dextran hydrogels in vitro and in vivo
    • Dogan AK, Gümüsderelioglu M, Aksoz E (2005) Controlled release of EGF and bFGF from dextran hydrogels in vitro and in vivo. J Biomed Mater Res B Appl Biomater 74 (1):504-510
    • (2005) J Biomed Mater Res B Appl Biomater , vol.74 , Issue.1 , pp. 504-510
    • Dogan, A.K.1    Gümüsderelioglu, M.2    Aksoz, E.3
  • 164
    • 10644233978 scopus 로고    scopus 로고
    • In vitro characterization of vascular endothelial growth factor and dexamethasone releasing hydrogels for implantable probe coatings
    • Norton LW, Tegnella E, Toporekb SS, Reichert WM (2005) In vitro characterization of vascular endothelial growth factor and dexamethasone releasing hydrogels for implantable probe coatings. Biomaterials 26:3285-3297
    • (2005) Biomaterials , vol.26 , pp. 3285-3297
    • Norton, L.W.1    Tegnella, E.2    Toporekb, S.S.3    Reichert, W.M.4
  • 165
    • 36048941406 scopus 로고    scopus 로고
    • Photo-crosslinkable and biodegradable Pluronic/heparin hydrogels for local and sustained delivery of angiogenic growth factor
    • Yoon JJ, Chung HJ, Park TG (2007) Photo-crosslinkable and biodegradable Pluronic/heparin hydrogels for local and sustained delivery of angiogenic growth factor. J Biomed Mater Res A 83 (3):597-605
    • (2007) J Biomed Mater Res A , vol.83 , Issue.3 , pp. 597-605
    • Yoon, J.J.1    Chung, H.J.2    Park, T.G.3
  • 166
    • 44549087624 scopus 로고    scopus 로고
    • Immobilization of glycoproteins, such as VEGF, on biodegradable substrates
    • Sharon JL, Puleo DA (2008) Immobilization of glycoproteins, such as VEGF, on biodegradable substrates. Acta Biomater 4 (4):1016-1023
    • (2008) Acta Biomater , vol.4 , Issue.4 , pp. 1016-1023
    • Sharon, J.L.1    Puleo, D.A.2
  • 168
    • 0034672889 scopus 로고    scopus 로고
    • Sustained release of vascular endothelial growth factor from mineralized poly (lactide-co-glycolide) scaffolds for tissue engineering
    • Murphy WL, Peters MC, Kohn DH, Mooney DJ (2000) Sustained release of vascular endothelial growth factor from mineralized poly (lactide-co-glycolide) scaffolds for tissue engineering. Biomaterials 21 (24):2521-2527
    • (2000) Biomaterials , vol.21 , Issue.24 , pp. 2521-2527
    • Murphy, W.L.1    Peters, M.C.2    Kohn, D.H.3    Mooney, D.J.4
  • 170
    • 0033017213 scopus 로고    scopus 로고
    • DNA delivery from polymer matrices for tissue engineering
    • Shea LD, Smiley E, Bonadio J, Mooney DJ (1999) DNA delivery from polymer matrices for tissue engineering. Nat Biotechnol 17:551-554
    • (1999) Nat Biotechnol , vol.17 , pp. 551-554
    • Shea, L.D.1    Smiley, E.2    Bonadio, J.3    Mooney, D.J.4
  • 171
    • 0030199526 scopus 로고    scopus 로고
    • Novel approach to fabricate porous sponges of poly (D, L-lacticco-glycolic acid) without the use of organic solvents
    • Mooney DJ, Baldwin DF, Suh NP, Vacanti JP, Langer R (1996) Novel approach to fabricate porous sponges of poly (D, L-lacticco-glycolic acid) without the use of organic solvents. Biomaterials 17:1417-1422
    • (1996) Biomaterials , vol.17 , pp. 1417-1422
    • Mooney, D.J.1    Baldwin, D.F.2    Suh, N.P.3    Vacanti, J.P.4    Langer, R.5
  • 172
    • 0036342371 scopus 로고    scopus 로고
    • Development of an injectable, in situ crosslinkable, degradable polymeric carrier for osteogenic cell populations. Part 3. Proliferation and differentiation of encapsulated marrow stromal osteoblasts cultured on crosslinking poly (propylene fumarate)
    • Payne RG, McGonigle JS, Yaszemski MJ, Yasko AW, Mikos AG (2002) Development of an injectable, in situ crosslinkable, degradable polymeric carrier for osteogenic cell populations. Part 3. Proliferation and differentiation of encapsulated marrow stromal osteoblasts cultured on crosslinking poly (propylene fumarate). Biomaterials 23:4381-4387
    • (2002) Biomaterials , vol.23 , pp. 4381-4387
    • Payne, R.G.1    McGonigle, J.S.2    Yaszemski, M.J.3    Yasko, A.W.4    Mikos, A.G.5
  • 174
    • 1342346686 scopus 로고    scopus 로고
    • Spatial and temporal control of angiogenesis and arterialization using focal applications of VEGF164 and Ang-1
    • Peirce SM, Price RJ, Skalak TC (2004) Spatial and temporal control of angiogenesis and arterialization using focal applications of VEGF164 and Ang-1. Am J Physiol Heart Circ Physiol 286:H918-H925
    • (2004) Am J Physiol Heart Circ Physiol , vol.286
    • Peirce, S.M.1    Price, R.J.2    Skalak, T.C.3
  • 175
    • 57349143801 scopus 로고    scopus 로고
    • A new double emulsion solvent diffusion technique for encapsulating hydrophilic molecules in PLGA nanoparticles
    • Cohen-Sela E, Chorny M, Koroukhov N, Danenberg HD, Golomb G (2009) A new double emulsion solvent diffusion technique for encapsulating hydrophilic molecules in PLGA nanoparticles. J Control Release 133 (2):90-95
    • (2009) J Control Release , vol.133 , Issue.2 , pp. 90-95
    • Cohen-Sela, E.1    Chorny, M.2    Koroukhov, N.3    Danenberg, H.D.4    Golomb, G.5
  • 176
    • 33746253246 scopus 로고    scopus 로고
    • Influence of microencapsulation method and peptide loading on formulation of poly (lactide-co-glycolide) insulin nanoparticles
    • Kumar PS, Ramakrishna S, Saini TR, Diwan PV (2006) Influence of microencapsulation method and peptide loading on formulation of poly (lactide-co-glycolide) insulin nanoparticles. Pharmazie 61 (7):613-617
    • (2006) Pharmazie , vol.61 , Issue.7 , pp. 613-617
    • Kumar, P.S.1    Ramakrishna, S.2    Saini, T.R.3    Diwan, P.V.4
  • 177
    • 14844317382 scopus 로고    scopus 로고
    • Strategic approaches for overcoming peptide and protein instability within biodegradable nano- and microparticles
    • Bilati U, Allemann E, Doelker E (2005) Strategic approaches for overcoming peptide and protein instability within biodegradable nano- and microparticles. Eur J Pharm Biopharm 59 (3):375-388
    • (2005) Eur J Pharm Biopharm , vol.59 , Issue.3 , pp. 375-388
    • Bilati, U.1    Allemann, E.2    Doelker, E.3
  • 179
    • 48149090216 scopus 로고    scopus 로고
    • Sustained release of bioactive glycosylated glial cell-line derived neurotrophic factor from biodegradable polymeric microspheres
    • Garbayo E, Ansorena E, Lanciego JL, Aymerich MS, Blanco- Prieto MJ (2008) Sustained release of bioactive glycosylated glial cell-line derived neurotrophic factor from biodegradable polymeric microspheres. Eur J Pharm Biopharm 69:844-851
    • (2008) Eur J Pharm Biopharm , vol.69 , pp. 844-851
    • Garbayo, E.1    Ansorena, E.2    Lanciego, J.L.3    Aymerich, M.S.4    Blanco- Prieto, M.J.5
  • 180
    • 77953259887 scopus 로고    scopus 로고
    • Active blood vessel formation in the ischemic hindlimb mouse model using a microsphere/hydrogel combination system
    • Lee J, Bhang SH, Park H, Kim BS, Lee KY (2010) Active blood vessel formation in the ischemic hindlimb mouse model using a microsphere/hydrogel combination system. Pharm Res 27 (5): 767-774
    • (2010) Pharm Res , vol.27 , Issue.5 , pp. 767-774
    • Lee, J.1    Bhang, S.H.2    Park, H.3    Kim, B.S.4    Lee, K.Y.5
  • 181
    • 77949270271 scopus 로고    scopus 로고
    • Sustained release of multiple growth factors from injectable polymeric system as a novel therapeutic approach towards angiogenesis
    • Sun Q, Silva E, Wang A, Fritton JC, Mooney DJ, Schaffler MB, Grossman PM, Rajagopalan S (2010) Sustained release of multiple growth factors from injectable polymeric system as a novel therapeutic approach towards angiogenesis. Pharm Res 27 (2):264-271
    • (2010) Pharm Res , vol.27 , Issue.2 , pp. 264-271
    • Sun, Q.1    Silva, E.2    Wang, A.3    Fritton, J.C.4    Mooney, D.J.5    Schaffler, M.B.6    Grossman, P.M.7    Rajagopalan, S.8
  • 183
    • 0032990851 scopus 로고    scopus 로고
    • Heat shock proteins delivered with a virus vector can protect cardiac cells against apoptosis as well as against thermal or hypoxic stress
    • Brar BK, Stephanou A, Wagstaff MJ, Coffin RS, Marber MS, Engelmann G, Latchman DS (1999) Heat shock proteins delivered with a virus vector can protect cardiac cells against apoptosis as well as against thermal or hypoxic stress. J Mol Cell Cardiol 31 (1):135-146
    • (1999) J Mol Cell Cardiol , vol.31 , Issue.1 , pp. 135-146
    • Brar, B.K.1    Stephanou, A.2    Wagstaff, M.J.3    Coffin, R.S.4    Marber, M.S.5    Engelmann, G.6    Latchman, D.S.7
  • 184
    • 67649236178 scopus 로고    scopus 로고
    • Controlled delivery of heat shock protein using an injectable microsphere/ hydrogel combination system for the treatment of myocardial infarction
    • Lee J, Tan CY, Lee SK, Kim YH, Lee KY (2009) Controlled delivery of heat shock protein using an injectable microsphere/ hydrogel combination system for the treatment of myocardial infarction. J Control Release 137 (3):196-202
    • (2009) J Control Release , vol.137 , Issue.3 , pp. 196-202
    • Lee, J.1    Tan, C.Y.2    Lee, S.K.3    Kim, Y.H.4    Lee, K.Y.5
  • 185
    • 65549114958 scopus 로고    scopus 로고
    • In vitro characterization of hepatocyte growth factor release from PHBV/PLGA microsphere scaffold
    • Zhu XH, Wang CH, Tong YW (2009) In vitro characterization of hepatocyte growth factor release from PHBV/PLGA microsphere scaffold. J Biomed Mater Res A 89 (2):411-423
    • (2009) J Biomed Mater Res A , vol.89 , Issue.2 , pp. 411-423
    • Zhu, X.H.1    Wang, C.H.2    Tong, Y.W.3
  • 186
    • 0032078388 scopus 로고    scopus 로고
    • Recombinant human erythropoietin (rhEPO) loaded poly (lactide-co- glycolide) microspheres: Influence of the encapsulation technique and polymer purity on microsphere characteristics
    • Bittner B, Morlock M, Koll H, Winter G, Kissel T (1998) Recombinant human erythropoietin (rhEPO) loaded poly (lactide-co-glycolide) microspheres: influence of the encapsulation technique and polymer purity on microsphere characteristics. Eur J Pharm Biopharm 45 (3):295-305
    • (1998) Eur J Pharm Biopharm , vol.45 , Issue.3 , pp. 295-305
    • Bittner, B.1    Morlock, M.2    Koll, H.3    Winter, G.4    Kissel, T.5
  • 187
    • 33745335884 scopus 로고    scopus 로고
    • In vitro characteristics of poly (lactic-co-glycolic acid) microspheres incorporating gelatin particles loading basic fibroblast growth factor
    • Li SH, Cai SX, Liu B, Ma KW, Wang ZP, Li XK (2006) In vitro characteristics of poly (lactic-co-glycolic acid) microspheres incorporating gelatin particles loading basic fibroblast growth factor. Acta Pharmacol Sin 27 (6):754-759
    • (2006) Acta Pharmacol Sin , vol.27 , Issue.6 , pp. 754-759
    • Li, S.H.1    Cai, S.X.2    Liu, B.3    Ma, K.W.4    Wang, Z.P.5    Li, X.K.6
  • 188
    • 77953959247 scopus 로고    scopus 로고
    • VEGF-induced angiogenesis following localized delivery via injectable, low viscosity poly (trimethylene carbonate)
    • Amsden BG, Timbart L, Marecak D, Chapanian R, Tse MY, Pang SC (2010) VEGF-induced angiogenesis following localized delivery via injectable, low viscosity poly (trimethylene carbonate). J Control Release 145 (2):109-115
    • (2010) J Control Release , vol.145 , Issue.2 , pp. 109-115
    • Amsden, B.G.1    Timbart, L.2    Marecak, D.3    Chapanian, R.4    Tse, M.Y.5    Pang, S.C.6
  • 190
    • 77957949816 scopus 로고    scopus 로고
    • Heparinized chitosan/poly (gamma-glutamic acid) nanoparticles for multi-functional delivery of fibroblast growth factor and heparin
    • Tang DW, Yu SH, Ho YC, Mi FL, Kuo PL, Sung HW (2010) Heparinized chitosan/poly (gamma-glutamic acid) nanoparticles for multi-functional delivery of fibroblast growth factor and heparin. Biomaterials 31 (35):9320-9332
    • (2010) Biomaterials , vol.31 , Issue.35 , pp. 9320-9332
    • Tang, D.W.1    Yu, S.H.2    Ho, Y.C.3    Mi, F.L.4    Kuo, P.L.5    Sung, H.W.6
  • 191
    • 77957739081 scopus 로고    scopus 로고
    • Hyaluronic acid/Chitosan nanoparticles as delivery vehicles for VEGF and PDGF-BB
    • Parajo Y, D'Angelo I, Welle A, Garcia-Fuentes M, Alonso MJ (2010) Hyaluronic acid/Chitosan nanoparticles as delivery vehicles for VEGF and PDGF-BB. Drug Deliv 17 (8):596-604
    • (2010) Drug Deliv , vol.17 , Issue.8 , pp. 596-604
    • Parajo, Y.1    D'angelo, I.2    Welle, A.3    Garcia-Fuentes, M.4    Alonso, M.J.5
  • 192
    • 77953259887 scopus 로고    scopus 로고
    • Active blood vessel formation in the ischemic hindlimb mouse model using; Rfaut microsphere/hydrogel combination system
    • Lee J, Bhang SH, Park H, Kim BS, Lee KY (2010) Active blood vessel formation in the ischemic hindlimb mouse model using; rfaut microsphere/hydrogel combination system. Pharm Res 27 (5): 767-774
    • (2010) Pharm Res , vol.27 , Issue.5 , pp. 767-774
    • Lee, J.1    Bhang, S.H.2    Park, H.3    Kim, B.S.4    Lee, K.Y.5
  • 193
    • 77949270271 scopus 로고    scopus 로고
    • Sustained release of multiple growth factors from injectable polymeric system as a novel therapeutic approach towards angiogenesis
    • Sun Q, Silva EA, Wang A, Fritton JC, Mooney DJ, Schaffler MB, Grossman PM, Rajagopalan S (2010) Sustained release of multiple growth factors from injectable polymeric system as a novel therapeutic approach towards angiogenesis. Pharm Res 27 (2):264-271
    • (2010) Pharm Res , vol.27 , Issue.2 , pp. 264-271
    • Sun, Q.1    Silva, E.A.2    Wang, A.3    Fritton, J.C.4    Mooney, D.J.5    Schaffler, M.B.6    Grossman, P.M.7    Rajagopalan, S.8
  • 194
    • 0033984323 scopus 로고    scopus 로고
    • Bioabsorbable polymer scaffolds for tissue engineering capable of sustained growth factor delivery
    • Sheridan MH, Shea LD, Peters MC, Mooney DJ (2000) Bioabsorbable polymer scaffolds for tissue engineering capable of sustained growth factor delivery. J Control Release 64:91-102
    • (2000) J Control Release , vol.64 , pp. 91-102
    • Sheridan, M.H.1    Shea, L.D.2    Peters, M.C.3    Mooney, D.J.4
  • 196
    • 77952236694 scopus 로고    scopus 로고
    • Efficient revascularization by VEGF administration via heparin-functionalized nanoparticle-fibrin complex
    • Chung YI, Kim SK, Lee YK, Park SJ, Cho KO, Yuk SH, Tae G, Kim YH (2010) Efficient revascularization by VEGF administration via heparin-functionalized nanoparticle-fibrin complex. J Control Release 143:282-289
    • (2010) J Control Release , vol.143 , pp. 282-289
    • Chung, Y.I.1    Kim, S.K.2    Lee, Y.K.3    Park, S.J.4    Cho, K.O.5    Yuk, S.H.6    Tae, G.7    Kim, Y.H.8
  • 197
    • 72749093756 scopus 로고    scopus 로고
    • Recent developments in liposomes, microparticles and nanoparticles for protein and peptide drug delivery
    • Tan ML, Choong PF, Dass CR (2010) Recent developments in liposomes, microparticles and nanoparticles for protein and peptide drug delivery. Peptides 31 (1):184-193
    • (2010) Peptides , vol.31 , Issue.1 , pp. 184-193
    • Tan, M.L.1    Choong, P.F.2    Dass, C.R.3
  • 198
    • 20444430090 scopus 로고    scopus 로고
    • Transport of nerve growth factor encapsulated into liposomes across the blood-brain barrier: In vitro and in vivo studies
    • Xie Y, Ye L, Zhang X, Cui W, Lou J, Nagai T, Hou X (2005) Transport of nerve growth factor encapsulated into liposomes across the blood-brain barrier: in vitro and in vivo studies. J Control Release 105 (1-2):106-119
    • (2005) J Control Release , vol.105 , Issue.1-2 , pp. 106-119
    • Xie, Y.1    Ye, L.2    Zhang, X.3    Cui, W.4    Lou, J.5    Nagai, T.6    Hou, X.7
  • 199
    • 27744464781 scopus 로고    scopus 로고
    • ATP-loaded liposomes effectively protect mechanical functions of the myocardium from global ischemia in an isolated rat heart model
    • Verma DD, Levchenko TS, Bernstein EA, Torchilin VP (2005) ATP-loaded liposomes effectively protect mechanical functions of the myocardium from global ischemia in an isolated rat heart model. J Control Release 108 (2-3):460-471
    • (2005) J Control Release , vol.108 , Issue.2-3 , pp. 460-471
    • Verma, D.D.1    Levchenko, T.S.2    Bernstein, E.A.3    Torchilin, V.P.4
  • 201
    • 0347996095 scopus 로고    scopus 로고
    • Increased accumulation of PEG-PE micelles in the area of experimental myocardial infarction in rabbits
    • Lukyanov AN, Hartner WC, Torchilin VP (2004) Increased accumulation of PEG-PE micelles in the area of experimental myocardial infarction in rabbits. J Control Release 94 (1): 187-193
    • (2004) J Control Release , vol.94 , Issue.1 , pp. 187-193
    • Lukyanov, A.N.1    Hartner, W.C.2    Torchilin, V.P.3
  • 203
    • 0344825937 scopus 로고    scopus 로고
    • Small-angle X-ray scattering study of the interaction of poly (ethylene oxide)-bpoly ( propylene oxide)-b-poly (ethylene oxide) triblock copolymers with lipid bilayers
    • Firestone MA, Wolf AC, Seifert S (2003) Small-angle X-ray scattering study of the interaction of poly (ethylene oxide)-bpoly ( propylene oxide)-b-poly (ethylene oxide) triblock copolymers with lipid bilayers. Biomacromolecules 4 (6):1539-1549
    • (2003) Biomacromolecules , vol.4 , Issue.6 , pp. 1539-1549
    • Firestone, M.A.1    Wolf, A.C.2    Seifert, S.3
  • 204
    • 33750136313 scopus 로고    scopus 로고
    • Current state, achievements, and future prospects of polymeric micelles as nanocarriers for drug and gene delivery
    • Nishiyama N, Kataoka K (2006) Current state, achievements, and future prospects of polymeric micelles as nanocarriers for drug and gene delivery. Pharmacol Ther 112:630-648
    • (2006) Pharmacol Ther , vol.112 , pp. 630-648
    • Nishiyama, N.1    Kataoka, K.2
  • 205
    • 33846644519 scopus 로고    scopus 로고
    • Heparin conjugated polymeric micelle for long-terin delivery of basic fibroblast growth factor
    • Lee JS, Go DH, Bae JW, Lee SJ, Park KD (2007) Heparin conjugated polymeric micelle for long-terin delivery of basic fibroblast growth factor. J Control Rel 117:204-209
    • (2007) J Control Rel , vol.117 , pp. 204-209
    • Lee, J.S.1    Go, D.H.2    Bae, J.W.3    Lee, S.J.4    Park, K.D.5
  • 206
    • 34250001748 scopus 로고    scopus 로고
    • Mesoporous silica nanoparticles deliver DNA and chemicals into plants
    • Torney F, Trewyn BG, Lin VSY, Wang K (2007) Mesoporous silica nanoparticles deliver DNA and chemicals into plants. Nat Nanotechnol 2:295-300
    • (2007) Nat Nanotechnol , vol.2 , pp. 295-300
    • Torney, F.1    Trewyn, B.G.2    Vsy, L.3    Wang, K.4
  • 207
  • 208
    • 79851473442 scopus 로고    scopus 로고
    • Targeted delivery of nanoparticles to ischemic muscle for imaging and therapeutic angiogenesis
    • Kim J, Cao L, Shvartsman D, Silva EA, Mooney DJ (2011) Targeted delivery of nanoparticles to ischemic muscle for imaging and therapeutic angiogenesis. Nano Lett 11 (2):694-700
    • (2011) Nano Lett , vol.11 , Issue.2 , pp. 694-700
    • Kim, J.1    Cao, L.2    Shvartsman, D.3    Silva, E.A.4    Mooney, D.J.5
  • 209
    • 77955769300 scopus 로고    scopus 로고
    • Sequential delivery of vascular endothelial growth factor and sphingosine 1-phosphate for angiogenesis
    • Tengood JE, Kovach KM, Vescovi PE, Russell AJ, Little SR (2010) Sequential delivery of vascular endothelial growth factor and sphingosine 1-phosphate for angiogenesis. Biomaterials 31 (30):7805-7812
    • (2010) Biomaterials , vol.31 , Issue.30 , pp. 7805-7812
    • Tengood, J.E.1    Kovach, K.M.2    Vescovi, P.E.3    Russell, A.J.4    Little, S.R.5
  • 210
    • 0033517733 scopus 로고    scopus 로고
    • Local perivascular delivery of basic fibroblast growth factor in patients undergoing coronary bypass surgery: Results of a phase i randomized, double-blind, placebo-controlled trial
    • Laham RJ, Sellke FW, Edelman ER, Pearlman JD, Ware JA, Brown DL, Gold JP, Simons M (1999) Local perivascular delivery of basic fibroblast growth factor in patients undergoing coronary bypass surgery: results of a phase I randomized, double-blind, placebo-controlled trial. Circulation 100 (18):1865-1871
    • (1999) Circulation , vol.100 , Issue.18 , pp. 1865-1871
    • Laham, R.J.1    Sellke, F.W.2    Edelman, E.R.3    Pearlman, J.D.4    Ware, J.A.5    Brown, D.L.6    Gold, J.P.7    Simons, M.8
  • 212
    • 65449173639 scopus 로고    scopus 로고
    • Cell therapies for therapeutic angiogenesis: Back to the bench
    • Sieveking DP, Ng MK (2009) Cell therapies for therapeutic angiogenesis: back to the bench. Vasc Med 14 (2):153-166
    • (2009) Vasc Med , vol.14 , Issue.2 , pp. 153-166
    • Sieveking, D.P.1    Ng, M.K.2
  • 215
    • 77953650323 scopus 로고    scopus 로고
    • Toward delivery of multiple growth factors in tissue engineering
    • Chen FM, Zhang M, Wu ZF (2010) Toward delivery of multiple growth factors in tissue engineering. Biomaterials 31 (24): 6279-6308
    • (2010) Biomaterials , vol.31 , Issue.24 , pp. 6279-6308
    • Chen, F.M.1    Zhang, M.2    Wu, Z.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.