Transport of nerve growth factor encapsulated into liposomes across the blood-brain barrier: In vitro and in vivo studies

Journal of Controlled Release

Volumn 105, Issue 1-2, 2005, Pages 106-119

  Xie, Ying ^a   Ye, Liya ^b   Zhang, Xiaobin ^a   Cui, Wei ^a   Lou, Jinning ^b   Nagai, Tsuneji ^c   Hou, Xinpu ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b CHINA JAPAN FRIENDSHIP HOSPITAL   (China)

^c HOSHI UNIVERSITY   (Japan)

Author keywords

In vitro and in vivo studies; In vitro BBB model; Liposomes; NGF; RMP 7

Indexed keywords

BLOOD; BRAIN; CELLS; DEGRADATION; ELECTRIC RESISTANCE; ENZYMES; LIPIDS; POLYETHYLENES;

BLOOD-BRAIN BARRIER (BBB); BRAIN MICROVASCULAR ENDOTHELIAL CELLS (BMVEC); LIPOSOMES; NERVE GROWTH FACTOR (NGF);

NEUROLOGY;

1,2 DIOLEOYLGLYCERO 3 PHOSPHOETHANOLAMINE[POLY(ETHYLENEGLYCOL)]SUCCINAMIDE; LIPOSOME; LOBRADIMIL; NERVE GROWTH FACTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CORTEX; BRAIN STEM; CEREBELLUM; CONTROLLED STUDY; CORPUS STRIATUM; DRUG DELIVERY SYSTEM; DRUG PENETRATION; DRUG TRANSPORT; ELECTRIC RESISTANCE; ENCAPSULATION; ENZYME DEGRADATION; HIPPOCAMPUS; IN VITRO STUDY; IN VIVO STUDY; MEMBRANE RESISTANCE; MOUSE; NONHUMAN; OLFACTORY BULB; PRIORITY JOURNAL; RAT;

ANIMALS; BIOLOGICAL TRANSPORT, ACTIVE; BLOOD-BRAIN BARRIER; CELL MEMBRANE PERMEABILITY; DRUG CARRIERS; ELECTRIC CONDUCTIVITY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCENT DYES; IODINE RADIOISOTOPES; LIPOSOMES; MICE; MICE, INBRED BALB C; NERVE GROWTH FACTORS;

EID: 20444430090     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2005.03.005     Document Type: Article

References (32)

1. T. Jamal, S. Jean-Michel, R.R. Anthony, and K. Michel Brain drug delivery technologies: novel approaches for transporting therapeutics Pharm. Sci. Technol. Today 3 2000 155 162
2. W.M. Pardrige New approaches to drug delivery through the blood-brain barrier Trends Biotechnol. 12 1994 239 245
3. P. Jolliet-Riant, and J.P. Tillement Drug transfer across the blood-brain barrier and improvement of brain delivery Fundam. Clin. Pharmacol. 13 1999 16 26
4. S.I. Rapoport Modulation of blood-brain barrier permeability J. Drug Target. 3 1996 417 425
5. J. Greenwood Experimental manipulation of the blood-brain and blood-retinal barriers. In physiology and pharmacology of the blood-brain barrier M.W.B. Bradbury N.J. Abbott Handbook of Experimental Pharmacology 1992 Springer-Verlag Berlin, Germany 459 486
6. W.M. Pardridge Non-invasive drug delivery to the human brain using endogenous blood-brain barrier transports systems Pharm. Sci. Technol. Today 2 1999 49 59
7. D. Maysinger, and A. Morinville Drug delivery to the nervous system Trends Biotechnol. 15 1997 410 418
8. J. Huwyler, D.F. Wu, and W.M. Pardridge Brain drug delivery of small molecules using immunoloposomes Proc. Natl. Acad. Sci. U. S. A. 93 11 1996 14164 14169
9. A.L. Klibanov, K. Maruyama, and V.P. Torchilin Amphipatic PEG effectively prolong the circulation time of liposomes FEBS Lett. 268 1990 235 237
10. P.M. Friden Receptor mediated transport of therapeutics across the blood-brain barrier Neurosurgery 35 1995 294 298
11. F.E. Dwaine, L.P. Reginald, and M. Joanne Intravenous cereport (RMP-7) enhances delivery of hydrophilic chemotherapeutics and increases survival in rats with metastatic tumors in the brain Pharm. Res. 17 2000 1212 1219
12. S.R. Doctrow, S.M. Abelleira, and L.A. Curry The bradykinin analog RMP-7 increases intracellular free calcium levels in rat brain microvascullar endothelial cell J. Pharmacol. Exp. Ther. 271 1994 229 237
13. J. Ford A phase I study of intravenous RMP-7 with carboplatin in patients with progression of malignant glioma Eur. J. Cancer 34 1998 1807 1811
14. T.S. Salahuddin Structural changes in the rat brain after carotid infusion of hyperosmolar solution. An electron microscopic study Acta Neuropathol. 77 1988 5 13
15. M.H. Tuszynski, K. Gabriel, and F.H. Gage Nerve growth factor delivery by gene transfer induces differential outgrowth of sensory motor and noradrenergic neuritis after adult spinal cord injury Exp. Neurol. 137 1996 157 173
16. J. Ye, and J.D. Houle Treatment at the chronically injured spinal cord with neurotrophic factors can promote axonal regeneration from supraspinal neurons Exp. Neurol. 143 1997 70 81
17. J.F. Poduslo, and G.L. Curran Permeability at the blood-brain and blood-nerve barriers of the neurotrophic factors: NGF, CNTF, NT-3, BDNF Mol. Brain Res. 36 1996 280 286
18. J.F. Poduslo, G.L. Curran, and P.J. Dyck Increase in albumin, IgG, and IgM blood-nerve barrier indices in human diabetic neuropathy Proc. Natl. Acad. Sci. U. S. A. 85 1988 4879 4883
19. J.F. Poduslo, P.A. Low, and A.J. Windebank Altered blood-nerve barrier in experimental lead neuropathy assessed by changes in endoneurial albumin concentration J. Neurosci. 21 1982 507 1514
20. F. Szoka Jr., and D. Papahadjopoulos Procedure for preparation of liposomes with large internal aqueous space and high capture by reverse-phase evaporation Proc. Natl. Acad. Sci. U. S. A. 75 1978 4194 4198
21. X.B. Zhang, J.Q. Xie, and S. Li The study on brain targeted of the Amphotericin B liposomes J. Drug Target. 11 2003 117 122
22. R. Adriana, and G. Lloyda The quantitative bioassay of nerve growth factor: use of frozen 'primed' PC12 pheochromocytoma cells Brain Res. 263 1983 177 180
23. J.N. Lou, Y. Gasche, and L. Zheng Differential reactivity of brain microvascular endothelial cells to TNF reflects the genetic susceptibility to cerebral malaria Eur. J. Immunol. 28 1998 3989 4000
24. H. Fenke, H.J. Galla, and C.T. Beuckmann Primary cultures of brain microvessel endothelial cells: a valid and flexible model to study drug transport through the blood-brain barrier in vitro Brain Res. Protoc. 5 2000 248 256
25. P.-A. Lapchak, D.-M. Araujo, S. Carswell, and F. Hefti Distribution of [125I]nerve growth factor in the rat brain following a single intraventricular injection: correlation with the topographical distribution of trkA messenger RNA-expressing cells Neuroscience 54 2 1993 445 460
26. J.G. Pieter, and G.B. Albertus Relationship between permeability status of the blood-brain barrier and in vitro permeability coefficient of a drug Eur. J. Pharm. Sci. 12 2000 95 102
27. H. Franke, H.J. Galla, and C.T. Beuckmann An improved low-permeability in vitro model of the blood-brain barrier: transport studies on retinoids, sucrose, haloperidol, caffeine and mannitol Brain Res. 818 1999 65 71
28. J. Senior, C. Delgado, and D. Fisher Influence of surface hydrophilicity of liposomes on their interaction with plasma protein and clearance from the circulation: studies with PEG-coated vesicles Biochim. Biophys. Acta 1062 1991 77 82
29. K. Matsukado, M. Sugita, and K.L. Black Intracarotid low dose bradykinin infusion selectively increase tumor permeability through activation at bradykinin B2 receptors in malignant gliomas Brain Res. 792 1998 10 15
30. R.T. Bartus, P.J. Elliott, and R.L. Dean Controlled modulation of BBB permeability using the bradykinin agonist RMP-7 Exp. Neurol. 142 1 1996 14 28
31. M.P. Dehouck, P. Jolliet-Riant, and F. Bree Drug transfer across the blood-brain barrier: correlation between in vitro and in vivo models J. Neurochem. 58 1992 1790 1797
32. D.K. Hansen, D.O. Scott, and K.W. Otis Comparison of in vitro BBMEC permeability and in vivo CNS uptake by microdialysis sampling J. Pharm. Biomed. Anal. 27 2002 945 958