Angiogenic effects of dual gene transfer of bFGF and PDGF-BB after myocardial infarction

Biochemical and Biophysical Research Communications

Volumn 315, Issue 4, 2004, Pages 1058-1063

  Hao, X ^a   Mansson Broberg A ^a   Gustafsson, T ^b   Grinnemo, K H ^a   Blomberg, P ^c   Siddiqui, A J ^a   Wardell E ^a   Sylven C ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b Department of Clinical Physiology ^*  (Sweden)

^c NOVUM   (Sweden)

Author keywords

Angiogenesis; Arteriogenesis; bFGF; Myocardial infarction; PDGF BB; Plasmid

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR RECEPTOR; PLATELET DERIVED GROWTH FACTOR BB;

ACUTE HEART INFARCTION; ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERIOLE; ARTERY ENDOTHELIUM; ARTICLE; CAPILLARY BASEMENT MEMBRANE; CHRONICITY; CONTROLLED STUDY; HORIZONTAL GENE TRANSFER; ISOLATED HEART; NONHUMAN; PLASMID; PRIORITY JOURNAL; RAT;

EID: 1342324081     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.01.165     Document Type: Article

References (17)

1. Herttuala S.Y., Alitalo K. Gene transfer as a tool to induce therapeutic vascular growth. Nat. Med. 9:2003;694-701.
2. Isner J.M. Myocardial gene therapy. Nature. 415:2002;234-239.
3. Gospodarowicz D., Brown K.D., Birdwell C.R., Zetter B.R. Control of proliferation of human vascular endothelial cells. Characterization of the response of human umbilical vein endothelial cells to fibroblast growth factor, epidermal growth factor, and thrombin. J. Cell Biol. 77:1978;774-788.
4. Klein S., Roghani M., Rifkin D.B. Fibroblast growth factors as angiogenesis factors: new insight into their mechanism of action. EXS. 79:1997;159-192.
5. Slavin J. Fibroblast growth factors: at the heart of angiogenesis. Cell. Biol. Int. 19:1995;431-444.
6. Galzie Z., Kinsella A.R., Smith J.A. Fibroblast growth factors and their receptors. Biochem. Cell Biol. 75:1997;669-685.
7. Kawasuji M., Nagamine H., Ikeda M., Sakakibara N., Takemura H., Fujii S., Watanabe Y. Therapeutic angiogenesis with intramyocardial administration of basic fibroblast growth factor. Ann. Thorac. Surg. 69:2000;1155-1161.
8. Lindahl P., Bostrom H., Karlsson L., Hellstrom M., Kalen M., Betsholtz C. Role of platelet-derived growth factors in angiogenesis and alveogenesis. Curr. Top. Pathol. 93:1999;27-33.
9. Ishikawa F., Miyazono K., Hellman U., Drexler H., Wernstedt C., Hagiwara K., Usuki K., Takaku F., Risau W., Heldin C.H. Identification of angiogenic activity and the cloning and expression of platelet-derived endothelial cell growth factor. Nature. 338:1989;557-562.
10. Risau W., Drexler H., Mironov V., Smits A., Siegbahn A., Funa K., Heldin C.H. Platelet-derived growth factor is angiogenic in vivo. Growth Factors. 7:1992;261-266.
11. Carmeliet P. Angiogenesis in health and disease. Nat. Med. 9:2003;653-660.
12. Cao R., Brakenhielm E., Pawliuk R., Wariaro D., Post M.J., Wahlberg E., Leboulch P., Cao Y. Angiogenic synergism, vascular stability and improvement of hind-limb ischemia by a combination of PDGF-BB and FGF-2. Nat. Med. 9:2003;604-613.
13. Facchiano A., De Marchis F., Turchetti E., Facchiano F., Guglielmi M., Denaro A., Palumbo R., Scoccianti M., Capogrossi M.C. The chemotactic and mitogenic effects of platelet-derived growth factor-BB on rat aorta smooth muscle cells are inhibited by basic fibroblast growth factor. J. Cell Sci. 113:2000;2855-2863.
14. De Marchis F., Ribatti D., Giampietri C., Lentini A., Faraone D., Scoccianti M., Capogrossi M.C., Facchiano A. Platelet-derived growth factor inhibits basic fibroblast growth factor angiogenic properties in vitro and in vivo through its alpha receptor. Blood. 99:2002;2045-2053.
15. Heldin C.H., Westermark B. Mechanism of action and in vivo role of platelet-derived growth factor. Physiol. Rev. 79:1999;1283-1316.
16. Bonner J.C., Badgett A., Lindroos P.M., Coin P.G. Basic fibroblast growth factor induces expression of the PDGF receptor-α on human bronchial smooth muscle cells. Am. J. Physiol. 271:1996;L880-L888.
17. Sylvén C., Sarkar N., Wärdell E., Jämsä A., Blomberg P., Drvota V., Islam K. Protein and angiogenic dose-response expression of phVEGF-A(165) gene in rat myocardium. J. Thromb. Thrombolysis. 12:2001;151-156.