메뉴 건너뛰기




Volumn 294, Issue 4, 2008, Pages

The Adventures of Sonic Hedgehog in Development and Repair. III. Hedgehog processing and biological activity

Author keywords

Morphogen; Review

Indexed keywords

CHOLESTEROL; PROTEOHEPARAN SULFATE; SONIC HEDGEHOG PROTEIN;

EID: 42049104913     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00564.2007     Document Type: Review
Times cited : (35)

References (29)
  • 1
    • 0032474837 scopus 로고    scopus 로고
    • Bellaiche Y, The I, Perriomon N. Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion. Nature 394: 85-88, 1998.
    • Bellaiche Y, The I, Perriomon N. Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion. Nature 394: 85-88, 1998.
  • 2
    • 0033598964 scopus 로고    scopus 로고
    • Burke R, Nellen D, Bellotto M, Hafen E, Senti KA, Dickson BJ, Basler K. Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling sells. Cell 99: 803-815, 1999.
    • Burke R, Nellen D, Bellotto M, Hafen E, Senti KA, Dickson BJ, Basler K. Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling sells. Cell 99: 803-815, 1999.
  • 3
    • 0035860538 scopus 로고    scopus 로고
    • Skinny hedgehog, an acyltransferase required for palmitoylation and activity of the hedgehog signal
    • Chamoun Z, Mann RK, Nellen D, von Kessler DP, Bellotto M, Beachy PA, Basler K. Skinny hedgehog, an acyltransferase required for palmitoylation and activity of the hedgehog signal. Science 293: 2080-2084, 2001.
    • (2001) Science , vol.293 , pp. 2080-2084
    • Chamoun, Z.1    Mann, R.K.2    Nellen, D.3    von Kessler, D.P.4    Bellotto, M.5    Beachy, P.A.6    Basler, K.7
  • 4
    • 1842853184 scopus 로고    scopus 로고
    • Palmitoylation is required for the production of a soluble multimeric Hedgehog protein complex and long-range signaling in vertebrates
    • Chen MH, Li YJ, Kawakami T, Xu SM, Chuang PT. Palmitoylation is required for the production of a soluble multimeric Hedgehog protein complex and long-range signaling in vertebrates. Genes Dev 18: 641-659, 2004.
    • (2004) Genes Dev , vol.18 , pp. 641-659
    • Chen, M.H.1    Li, Y.J.2    Kawakami, T.3    Xu, S.M.4    Chuang, P.T.5
  • 5
    • 33646914937 scopus 로고    scopus 로고
    • Ventral neural progenitors switch toward an oligodendroglial fate in response to increased Sonic hedgehog (Shh) activity: Involvement of Sulfatase 1 in modulating Shh signaling in the ventral spinal cord
    • Danesin C, Agius E, Escalas N, Ai X, Emerson C, Cochard P, Soula C. Ventral neural progenitors switch toward an oligodendroglial fate in response to increased Sonic hedgehog (Shh) activity: involvement of Sulfatase 1 in modulating Shh signaling in the ventral spinal cord. J Neurosci 26: 5037-5048, 2006.
    • (2006) J Neurosci , vol.26 , pp. 5037-5048
    • Danesin, C.1    Agius, E.2    Escalas, N.3    Ai, X.4    Emerson, C.5    Cochard, P.6    Soula, C.7
  • 6
    • 30644469247 scopus 로고    scopus 로고
    • Release and trafficking of lipid-linked morphogens
    • Eaton S. Release and trafficking of lipid-linked morphogens. Curr Opin Genet Dev 16: 17-22, 2006.
    • (2006) Curr Opin Genet Dev , vol.16 , pp. 17-22
    • Eaton, S.1
  • 7
    • 33747052036 scopus 로고    scopus 로고
    • The role of megalin (LRP-2/Gp330) during development
    • Fisher CE, Howie SE. The role of megalin (LRP-2/Gp330) during development. Dev Biol 296: 279-297, 2006.
    • (2006) Dev Biol , vol.296 , pp. 279-297
    • Fisher, C.E.1    Howie, S.E.2
  • 8
    • 0037321854 scopus 로고    scopus 로고
    • Cholesterol modification of hedgehog is required for trafficking and movement, revealing an asymmetric cellular response to hedgehog
    • Gallet A, Rodriguez R, Ruel L, Therond PP. Cholesterol modification of hedgehog is required for trafficking and movement, revealing an asymmetric cellular response to hedgehog. Dev Cell 4: 191-204, 2003.
    • (2003) Dev Cell , vol.4 , pp. 191-204
    • Gallet, A.1    Rodriguez, R.2    Ruel, L.3    Therond, P.P.4
  • 9
    • 33244482560 scopus 로고    scopus 로고
    • Cholesterol modification is necessary for controlled planar long-range activity of Hedgehog in Drosophila epithelia
    • Gallet A, Ruel L, Staccini-Lavenant L, Therond PP. Cholesterol modification is necessary for controlled planar long-range activity of Hedgehog in Drosophila epithelia. Development 133: 407-418, 2006.
    • (2006) Development , vol.133 , pp. 407-418
    • Gallet, A.1    Ruel, L.2    Staccini-Lavenant, L.3    Therond, P.P.4
  • 10
    • 33645228803 scopus 로고    scopus 로고
    • A highly conserved amino-terminal region of sonic hedgehog is required for the formation of its freely diffusible multimeric form
    • Goetz JA, Singh S, Suber LM, Kull FJ, Robbins DJ. A highly conserved amino-terminal region of sonic hedgehog is required for the formation of its freely diffusible multimeric form. J Biol Chem 281: 4087-4093, 2006.
    • (2006) J Biol Chem , vol.281 , pp. 4087-4093
    • Goetz, J.A.1    Singh, S.2    Suber, L.M.3    Kull, F.J.4    Robbins, D.J.5
  • 11
    • 33845873602 scopus 로고    scopus 로고
    • A conserved mechanism of Hedgehog gradient formation by lipid modifications
    • Guerrero I, Chiang C. A conserved mechanism of Hedgehog gradient formation by lipid modifications. Trends Cell Biol 17: 1-5, 2007.
    • (2007) Trends Cell Biol , vol.17 , pp. 1-5
    • Guerrero, I.1    Chiang, C.2
  • 12
    • 0035577854 scopus 로고    scopus 로고
    • Hedgehog signaling in animal development: Paradigms and principles
    • Ingham PW, McMahon AP. Hedgehog signaling in animal development: paradigms and principles. Genes Dev 15: 3059-3087, 2001.
    • (2001) Genes Dev , vol.15 , pp. 3059-3087
    • Ingham, P.W.1    McMahon, A.P.2
  • 16
    • 12344310615 scopus 로고    scopus 로고
    • Functions of heparan sulfate proteoglycans in cell signaling during development
    • Lin X. Functions of heparan sulfate proteoglycans in cell signaling during development. Development 131: 6009-6021, 2004.
    • (2004) Development , vol.131 , pp. 6009-6021
    • Lin, X.1
  • 17
    • 2942742564 scopus 로고    scopus 로고
    • Novel lipid modifications of secreted protein signals
    • Mann RK, Beachy PA. Novel lipid modifications of secreted protein signals. Annu Rev Biochem 73: 891-923, 2004.
    • (2004) Annu Rev Biochem , vol.73 , pp. 891-923
    • Mann, R.K.1    Beachy, P.A.2
  • 20
    • 0029844192 scopus 로고    scopus 로고
    • Cholesterol modification of hedgehog signaling proteins in animal development
    • Porter JA, Young KE, Beachy PA. Cholesterol modification of hedgehog signaling proteins in animal development. Science 274: 255-259, 1996.
    • (1996) Science , vol.274 , pp. 255-259
    • Porter, J.A.1    Young, K.E.2    Beachy, P.A.3
  • 21
    • 0033597141 scopus 로고    scopus 로고
    • Association of sterol- and glycosoylphosphatidylinositol-linked proteins with Drosophila raft lipid microdomains
    • Rietveld A, Neutz S, Simons K, Eaton S. Association of sterol- and glycosoylphosphatidylinositol-linked proteins with Drosophila raft lipid microdomains. J Biol Chem 274: 12049-12054, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 12049-12054
    • Rietveld, A.1    Neutz, S.2    Simons, K.3    Eaton, S.4
  • 22
    • 34247853493 scopus 로고    scopus 로고
    • Hedgehogs: La dolce vita. Workshop on Hedgehog-Gli Signaling in Cancer and Stem Cells
    • Robbins DJ, Hebrok M. Hedgehogs: la dolce vita. Workshop on Hedgehog-Gli Signaling in Cancer and Stem Cells. EMBO Rep 8: 451-455, 2007.
    • (2007) EMBO Rep , vol.8 , pp. 451-455
    • Robbins, D.J.1    Hebrok, M.2
  • 23
    • 0029004233 scopus 로고
    • Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis
    • Roelink H, Porter JA, Chiang C, Tanabe Y, Chang DT, Beachy PA, Jessell TM. Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis. Cell 81: 445-455, 1995.
    • (1995) Cell , vol.81 , pp. 445-455
    • Roelink, H.1    Porter, J.A.2    Chiang, C.3    Tanabe, Y.4    Chang, D.T.5    Beachy, P.A.6    Jessell, T.M.7
  • 24
    • 0036341998 scopus 로고    scopus 로고
    • Cerebellar proteoglycans regulate sonic hedgehog responses during development
    • Rubin JB, Choi Y, Segal RA. Cerebellar proteoglycans regulate sonic hedgehog responses during development. Development 129: 2223-2232, 2002.
    • (2002) Development , vol.129 , pp. 2223-2232
    • Rubin, J.B.1    Choi, Y.2    Segal, R.A.3
  • 26
    • 23444443064 scopus 로고    scopus 로고
    • Mechanisms of Hedgehog gradient formation and interpretation
    • Torroja C, Gorfinkiel N, Guerrero I. Mechanisms of Hedgehog gradient formation and interpretation. J Neurobiol 64: 334-356, 2005.
    • (2005) J Neurobiol , vol.64 , pp. 334-356
    • Torroja, C.1    Gorfinkiel, N.2    Guerrero, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.