Spatiotemporal control of vascular endothelial growth factor delivery from injectable hydrogels enhances angiogenesis

Journal of Thrombosis and Haemostasis

Volumn 5, Issue 3, 2007, Pages 590-598

  Silva, E A ^a   Mooney, David J ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

Ischemic tissues; Peripheral vascular diseases; Regenerative medicine; Sustained and localized delivery; Synthetic extracellular matrices; Therapeutic agents

Indexed keywords

ALGINIC ACID; VASCULOTROPIN; ANGIOGENIC FACTOR; APOLIPOPROTEIN E; DRUG CARRIER; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL GROWTH FACTOR A, HUMAN; VASCULOTROPIN A;

ANGIOGENESIS; ANIMAL TISSUE; ARTICLE; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; HEART MUSCLE ISCHEMIA; HUMAN; HYDROGEL; LASER DOPPLER FLOWMETRY; MOUSE; NONHUMAN; PERFUSION WEIGHTED IMAGING; PRIORITY JOURNAL; TISSUE PERFUSION; ANIMAL; BLOOD FLOW; C57BL MOUSE; CELL CULTURE; CHEMISTRY; COMPARATIVE STUDY; DELAYED RELEASE FORMULATION; DISEASE MODEL; DRUG EFFECT; ENDOTHELIUM CELL; FEMALE; GENETICS; HINDLIMB; INJECTION; ISCHEMIA; METABOLISM; MOUSE MUTANT; PATHOPHYSIOLOGY; REPRODUCIBILITY; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; SOLUBILITY; TIME; VASCULARIZATION;

ALGINATES; ANGIOGENESIS INDUCING AGENTS; ANIMALS; APOLIPOPROTEINS E; CELLS, CULTURED; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; DISEASE MODELS, ANIMAL; DRUG CARRIERS; ENDOTHELIAL CELLS; FEMALE; HINDLIMB; HUMANS; HYDROGELS; INJECTIONS; ISCHEMIA; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE, SKELETAL; NEOVASCULARIZATION, PHYSIOLOGIC; RECOMBINANT PROTEINS; REGIONAL BLOOD FLOW; REPRODUCIBILITY OF RESULTS; SOLUBILITY; TIME FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 34247610438     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2007.02386.x     Document Type: Article

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