The angiopoietins: Yin and Yang in angiogenesis

Current Topics in Microbiology and Immunology

Volumn 237, Issue , 1999, Pages 173-185

  Davis, S ^a   Yancopoulos, G D ^a  

^a REGENERON PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOPOIETIN; PROTEIN; RECEPTOR; UNCLASSIFIED DRUG;

ANGIOGENESIS; BLOOD VESSEL; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; TRANSGENIC MOUSE;

MUS MUSCULUS;

EID: 0032890359     PISSN: 0070217X     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-642-59953-8_9     Document Type: Review

References (8)

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2. Carmeliet P, Ferreira V, Breier G, Pollefeyt S, Kieckens L, Gertsenstein M, Fahrig M, Vandenhoeck A, Harpal K, Eberhardt C, Declercq C, Pawling J, Moons L, Collen D, Risau W, Nagy A (1996) Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 380:435-139
3. Davis S, Gale NW, Aldrich TH, Maisonpierre PC, Lhotak V, Pawson T, Goldfarb M, Yancopoulos GD (1994) Ligands for the EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity. Science 266:816-819
4. Drake CJ, Little CD (1995) Exogenous vascular endothelial growth factor induces malformed and hyperfused vessels during embryonic neovascularization. Proc Natl Acad Sci USA 92:7657-7661
5. Dumont DJ, Yamaguchi TP, Conlon RA, Rossant J, Breitman ML (1992) Tek, novel tyrosine kinase gene located on mouse chromosome 4, is expressed in endothelial cells and their presumptive precursors. Oncogene 7:1471-1480
6. Dumont DJ, Gradwohl G, Fong G-H, Puri MC, Gerstenstein M, Auerbach A, Breitman ML (1994) Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo. Genes Dev 8:1897-1909
7. Ferrara N (1995) The role of vascular endothelial growth factor in pathological angiogensis. Breast Cancer Res Treatment 36:127-137
8. Ferrara N, Heinsohn H, Walter CE, Buting S, Thomas GR (1995) The regulation of blood vessel growth by vascular endothelial growth factor. Ann NY Acad Sci 752:246-256