Formation and stabilization model of the 42-mer Aβ radical: Implications for the long-lasting oxidative stress in Alzheimer's disease

Journal of the American Chemical Society

Volumn 127, Issue 43, 2005, Pages 15168-15174

  Murakami, Kazuma ^a   Irie, Kazuhiro ^a   Ohigashi, Hajime ^a   Hara, Hideyuki ^b   Nagao, Masaya ^a   Shimizu, Takahiko ^c   Shirasawa, Takuji ^c  

^a KYOTO UNIVERSITY   (Japan)

^b Bruker Corporation   (United States)

^c TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

MOLECULAR STRUCTURE; NEUROLOGY; PARAMAGNETIC RESONANCE; PROTEINS; TOXICITY;

AMYLOID FIBRILS; NEUROTOXICITY; RADICAL CATIONS; TYROSYL RADICAL;

DISEASES;

AMYLOID; AMYLOID BETA PROTEIN; CARBOXYLIC ACID; CATION; METHIONINE; PROLINE; TYROSINE;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; BIOPHYSICS; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; MODEL; NEUROTOXICITY; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PATHOGENESIS; RAT; REDUCTION;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; CATIONS; ELECTRON SPIN RESONANCE SPECTROSCOPY; FREE RADICALS; KINETICS; METHIONINE; MODELS, BIOLOGICAL; MODELS, MOLECULAR; OXIDATION-REDUCTION; OXIDATIVE STRESS; PEPTIDE FRAGMENTS; PEPTIDES; SULFHYDRYL COMPOUNDS; TYROSINE;

EID: 27544511750     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja054041c     Document Type: Article

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