-
1
-
-
0037699955
-
Angiogenesis in health and disease
-
Carmeliet P. Angiogenesis in health and disease. Nat Med. 2003;9: 653-660.
-
(2003)
Nat Med
, vol.9
, pp. 653-660
-
-
Carmeliet, P.1
-
2
-
-
0035745524
-
Arteriogenesis, a new concept of vascular adaptation in occlusive disease
-
Scholz D, Cai WJ, Schaper W. Arteriogenesis, a new concept of vascular adaptation in occlusive disease. Angiogenesis. 2001;4:247-257.
-
(2001)
Angiogenesis
, vol.4
, pp. 247-257
-
-
Scholz, D.1
Cai, W.J.2
Schaper, W.3
-
3
-
-
65549100177
-
The opening act: Vasculogenesis and the origins of circulation
-
Jin SW, Patterson C. The opening act: Vasculogenesis and the origins of circulation. Arterioscler Thromb Vasc Biol. 2009;29:623-629.
-
(2009)
Arterioscler Thromb Vasc Biol
, vol.29
, pp. 623-629
-
-
Jin, S.W.1
Patterson, C.2
-
4
-
-
39749140405
-
HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1alpha
-
Arany Z, Foo SY, Ma Y, Ruas JL, Bommi-Reddy A, Girnun G, Cooper M, Laznik D, Chinsomboon J, Rangwala S, Baek K, Rosenzweig A, Spiegelman B. HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1alpha. Nature. 2008;451: 1008-1012.
-
(2008)
Nature
, vol.451
, pp. 1008-1012
-
-
Arany, Z.1
Foo, S.Y.2
Ma, Y.3
Ruas, J.L.4
Bommi-Reddy, A.5
Girnun, G.6
Cooper, M.7
Laznik, D.8
Chinsomboon, J.9
Rangwala, S.10
Baek, K.11
Rosenzweig, A.12
Spiegelman, B.13
-
5
-
-
79251479441
-
Regulation of exercise-induced fiber type transformation, mitochondrial biogenesis, and angiogenesis in skeletal muscle
-
Yan Z, Okutsu M, Akhtar YN, Lira V. Regulation of exercise-induced fiber type transformation, mitochondrial biogenesis, and angiogenesis in skeletal muscle. J Appl Physiol. 2011;110:264-274.
-
(2011)
J Appl Physiol
, vol.110
, pp. 264-274
-
-
Yan, Z.1
Okutsu, M.2
Akhtar, Y.N.3
Lira, V.4
-
6
-
-
0032894826
-
Therapeutic angiogenesis for heart failure
-
Isner JM, Losordo DW. Therapeutic angiogenesis for heart failure. Nat Med. 1999;5:491-492.
-
(1999)
Nat Med
, vol.5
, pp. 491-492
-
-
Isner, J.M.1
Losordo, D.W.2
-
7
-
-
77957241701
-
Dynamics of endothelial cell behavior in sprouting angiogenesis
-
Eilken HM, Adams RH. Dynamics of endothelial cell behavior in sprouting angiogenesis. Curr Opin Cell Biol. 2010;22:617-625.
-
(2010)
Curr Opin Cell Biol
, vol.22
, pp. 617-625
-
-
Eilken, H.M.1
Adams, R.H.2
-
8
-
-
34247632152
-
Stem cells and the regeneration of the aging cardiovascular system
-
Ballard VL, Edelberg JM. Stem cells and the regeneration of the aging cardiovascular system. Circ Res. 2007;100:1116-1127.
-
(2007)
Circ Res
, vol.100
, pp. 1116-1127
-
-
Ballard, V.L.1
Edelberg, J.M.2
-
9
-
-
77952092300
-
Endothelial precursors in vascular repair
-
Kirton JP, Xu Q. Endothelial precursors in vascular repair. Microvasc Res. 2010;79:193-199.
-
(2010)
Microvasc Res
, vol.79
, pp. 193-199
-
-
Kirton, J.P.1
Xu, Q.2
-
10
-
-
24344457626
-
Circulating endothelial progenitors-cells as biomarkers
-
Rosenzweig A. Circulating endothelial progenitors-cells as biomarkers. N Engl J Med. 2005;353:1055-1057.
-
(2005)
N Engl J Med
, vol.353
, pp. 1055-1057
-
-
Rosenzweig, A.1
-
11
-
-
25444522479
-
Role of angiogenesis in cardiovascular disease: A critical appraisal
-
Khurana R, Simons M, Martin JF, Zachary I. Role of angiogenesis in cardiovascular disease: A critical appraisal. Circulation. 2005;112: 1813-1824.
-
(2005)
Circulation
, vol.112
, pp. 1813-1824
-
-
Khurana, R.1
Simons, M.2
Martin, J.F.3
Zachary, I.4
-
12
-
-
49949152069
-
Mechanisms of adaptive angiogenesis to tissue hypoxia
-
Fong GH. Mechanisms of adaptive angiogenesis to tissue hypoxia. Angiogenesis. 2008;11:121-140.
-
(2008)
Angiogenesis
, vol.11
, pp. 121-140
-
-
Fong, G.H.1
-
13
-
-
0038037735
-
Regulation of angiogenesis by hypoxia: Role of the HIF system
-
Pugh CW, Ratcliffe PJ. Regulation of angiogenesis by hypoxia: Role of the HIF system. Nat Med. 2003;9:677-684.
-
(2003)
Nat Med
, vol.9
, pp. 677-684
-
-
Pugh, C.W.1
Ratcliffe, P.J.2
-
14
-
-
0034594876
-
Early expression of angiogenesis factors in acute myocardial ischemia and infarction
-
Lee SH, Wolf PL, Escudero R, Deutsch R, Jamieson S, Thistlethwaite P. Early expression of angiogenesis factors in acute myocardial ischemia and infarction. N Engl J Med. 2000;342:626-633.
-
(2000)
N Engl J Med
, vol.342
, pp. 626-633
-
-
Lee, S.H.1
Wolf, P.L.2
Escudero, R.3
Deutsch, R.4
Jamieson, S.5
Thistlethwaite, P.6
-
15
-
-
0037362890
-
HIF hydroxylation and the mammalian oxygen-sensing pathway
-
Safran M, Kaelin WG Jr. HIF hydroxylation and the mammalian oxygen-sensing pathway. J Clin Invest. 2003;111:779-783.
-
(2003)
J Clin Invest
, vol.111
, pp. 779-783
-
-
Safran, M.1
Kaelin Jr., W.G.2
-
16
-
-
75849155745
-
The transcriptional coactivator PGC-1alpha mediates exercise-induced angiogenesis in skeletal muscle
-
Chinsomboon J, Ruas J, Gupta RK, Thom R, Shoag J, Rowe G, Sawada N, Raghuram S, Arany Z. The transcriptional coactivator PGC-1alpha mediates exercise-induced angiogenesis in skeletal muscle. Proc Natl Acad Sci USA. 2009;106:21401-21406.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 21401-21406
-
-
Chinsomboon, J.1
Ruas, J.2
Gupta, R.K.3
Thom, R.4
Shoag, J.5
Rowe, G.6
Sawada, N.7
Raghuram, S.8
Arany, Z.9
-
17
-
-
79956328903
-
Molecular mechanisms and clinical applications of angiogenesis
-
Carmeliet P, Jain RK. Molecular mechanisms and clinical applications of angiogenesis. Nature. 2011;473:298-307.
-
(2011)
Nature
, vol.473
, pp. 298-307
-
-
Carmeliet, P.1
Jain, R.K.2
-
18
-
-
0031829140
-
Acute lower limb ischemia: Determinants of outcome
-
discussion 341-332
-
Ouriel K, Veith F. Acute lower limb ischemia: Determinants of outcome. Surgery. 1998;124:336-341; discussion 341-332.
-
(1998)
Surgery
, vol.124
, pp. 336-341
-
-
Ouriel, K.1
Veith, F.2
-
19
-
-
36248979231
-
No difference in the skeletal muscle angiogenic response to aerobic exercise training between young and aged men
-
Gavin TP, Ruster RS, Carrithers JA, Zwetsloot KA, Kraus RM, Evans CA, Knapp DJ, Drew JL, McCartney JS, Garry JP, Hickner RC. No difference in the skeletal muscle angiogenic response to aerobic exercise training between young and aged men. J Physiol. 2007;585:231-239.
-
(2007)
J Physiol
, vol.585
, pp. 231-239
-
-
Gavin, T.P.1
Ruster, R.S.2
Carrithers, J.A.3
Zwetsloot, K.A.4
Kraus, R.M.5
Evans, C.A.6
Knapp, D.J.7
Drew, J.L.8
McCartney, J.S.9
Garry, J.P.10
Hickner, R.C.11
-
20
-
-
0015123989
-
Body composition, aerobic capacity, and density of muscle capillaries in young and old men
-
Parizkova J, Eiselt E, Sprynarova S, Wachtlova M. Body composition, aerobic capacity, and density of muscle capillaries in young and old men. J Appl Physiol. 1971;31:323-325.
-
(1971)
J Appl Physiol
, vol.31
, pp. 323-325
-
-
Parizkova, J.1
Eiselt, E.2
Sprynarova, S.3
Wachtlova, M.4
-
21
-
-
0026668204
-
Skeletal muscle adaptations to endurance training in 60-to 70-yr-old men and women
-
Coggan AR, Spina RJ, King DS, Rogers M, Brown M, Nemeth P, Holloszy J. Skeletal muscle adaptations to endurance training in 60-to 70-yr-old men and women. J Appl Physiol. 1992;72:1780-1786.
-
(1992)
J Appl Physiol
, vol.72
, pp. 1780-1786
-
-
Coggan, A.R.1
Spina, R.J.2
King, D.S.3
Rogers, M.4
Brown, M.5
Nemeth, P.6
Holloszy, J.7
-
22
-
-
70350126601
-
Human studies of angiogenic gene therapy
-
Gupta R, Tongers J, Losordo DW. Human studies of angiogenic gene therapy. Circ Res. 2009;105:724-736.
-
(2009)
Circ Res
, vol.105
, pp. 724-736
-
-
Gupta, R.1
Tongers, J.2
Losordo, D.W.3
-
23
-
-
0033547805
-
Age-dependent impairment of angiogenesis
-
Rivard A, Fabre JE, Silver M, Chen D, Murohara T, Kearney M, Magner M, Asahara T, Isner JM. Age-dependent impairment of angiogenesis. Circulation. 1999;99:111-120.
-
(1999)
Circulation
, vol.99
, pp. 111-120
-
-
Rivard, A.1
Fabre, J.E.2
Silver, M.3
Chen, D.4
Murohara, T.5
Kearney, M.6
Magner, M.7
Asahara, T.8
Isner, J.M.9
-
24
-
-
0033398390
-
Impaired wound repair and delayed angiogenesis in aged mice
-
Swift ME, Kleinman HK, DiPietro LA. Impaired wound repair and delayed angiogenesis in aged mice. Lab Invest. 1999;79:1479-1487.
-
(1999)
Lab Invest
, vol.79
, pp. 1479-1487
-
-
Swift, M.E.1
Kleinman, H.K.2
Dipietro, L.A.3
-
25
-
-
21344448869
-
Age is no barrier to muscle structural, biochemical and angiogenic adaptations to training up to 24 months in female rats
-
Rossiter HB, Howlett RA, Holcombe HH, Entin PL, Wagner HE, Wagner PD. Age is no barrier to muscle structural, biochemical and angiogenic adaptations to training up to 24 months in female rats. J Physiol. 2005;565:993-1005.
-
(2005)
J Physiol
, vol.565
, pp. 993-1005
-
-
Rossiter, H.B.1
Howlett, R.A.2
Holcombe, H.H.3
Entin, P.L.4
Wagner, H.E.5
Wagner, P.D.6
-
26
-
-
0028129545
-
Altered angiogenesis underlying age-dependent changes in tumor growth
-
Pili R, Guo Y, Chang J, Nakanishi H, Martin G, Passaniti A. Altered angiogenesis underlying age-dependent changes in tumor growth. J Natl Cancer Inst. 1994;86:1303-1314.
-
(1994)
J Natl Cancer Inst
, vol.86
, pp. 1303-1314
-
-
Pili, R.1
Guo, Y.2
Chang, J.3
Nakanishi, H.4
Martin, G.5
Passaniti, A.6
-
27
-
-
60349129368
-
Human endothelial function and microvascular ageing
-
Gates PE, Strain WD, Shore AC. Human endothelial function and microvascular ageing. Exp Physiol. 2009;94:311-316.
-
(2009)
Exp Physiol
, vol.94
, pp. 311-316
-
-
Gates, P.E.1
Strain, W.D.2
Shore, A.C.3
-
28
-
-
19544383551
-
Senescence and its bypass in the vascular endothelium
-
Freedman DA. Senescence and its bypass in the vascular endothelium. Front Biosci. 2005;10:940-950.
-
(2005)
Front Biosci
, vol.10
, pp. 940-950
-
-
Freedman, D.A.1
-
29
-
-
0141670454
-
Involvement of the INK4a/Arf gene locus in senescence
-
Collins CJ, Sedivy JM. Involvement of the INK4a/Arf gene locus in senescence. Aging Cell. 2003;2:145-150.
-
(2003)
Aging Cell
, vol.2
, pp. 145-150
-
-
Collins, C.J.1
Sedivy, J.M.2
-
30
-
-
40949085119
-
Cyclin-dependent kinase inhibitor p16(INK4a) and telomerase may co-modulate endothelial progenitor cells senescence
-
Yang DG, Liu L, Zheng XY. Cyclin-dependent kinase inhibitor p16(INK4a) and telomerase may co-modulate endothelial progenitor cells senescence. Ageing Res Rev. 2008;7:137-146.
-
(2008)
Ageing Res Rev
, vol.7
, pp. 137-146
-
-
Yang, D.G.1
Liu, L.2
Zheng, X.Y.3
-
32
-
-
79953738062
-
Cleaved high-molecularweight kininogen accelerates the onset of endothelial progenitor cell senescence by induction of reactive oxygen species
-
Dai J, Zhu X, Yoder MC, Wu Y, Colman R. Cleaved high-molecularweight kininogen accelerates the onset of endothelial progenitor cell senescence by induction of reactive oxygen species. Arterioscler Thromb Vasc Biol. 2011;31:883-889.
-
(2011)
Arterioscler Thromb Vasc Biol
, vol.31
, pp. 883-889
-
-
Dai, J.1
Zhu, X.2
Yoder, M.C.3
Wu, Y.4
Colman, R.5
-
33
-
-
0033049828
-
P16(INK4a) and the control of cellular proliferative life span
-
Huschtscha LI, Reddel RR. p16(INK4a) and the control of cellular proliferative life span. Carcinogenesis. 1999;20:921-926.
-
(1999)
Carcinogenesis
, vol.20
, pp. 921-926
-
-
Huschtscha, L.I.1
Reddel, R.R.2
-
34
-
-
77953168825
-
ARF suppresses tumor angiogenesis through translational control of VEGFA mRNA
-
Kawagishi H, Nakamura H, Maruyama M, Mizutani S, Sugimoto K, Takagi M, Sugimoto M. ARF suppresses tumor angiogenesis through translational control of VEGFA mRNA. Cancer Res. 2010;70: 4749-4758.
-
(2010)
Cancer Res
, vol.70
, pp. 4749-4758
-
-
Kawagishi, H.1
Nakamura, H.2
Maruyama, M.3
Mizutani, S.4
Sugimoto, K.5
Takagi, M.6
Sugimoto, M.7
-
35
-
-
0030999445
-
Vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) delays and induces escape from senescence in human dermal microvascular endothelial cells
-
Watanabe Y, Lee SW, Detmar M, Ajioka I, Dvorak H. Vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) delays and induces escape from senescence in human dermal microvascular endothelial cells. Oncogene. 1997;14:2025-2032.
-
(1997)
Oncogene
, vol.14
, pp. 2025-2032
-
-
Watanabe, Y.1
Lee, S.W.2
Detmar, M.3
Ajioka, I.4
Dvorak, H.5
-
36
-
-
34547623750
-
Genomewide association analysis of coronary artery disease
-
Samani NJ, Erdmann J, Hall AS, et al. Genomewide association analysis of coronary artery disease. N Engl J Med. 2007;357:443-453.
-
(2007)
N Engl J Med
, vol.357
, pp. 443-453
-
-
Samani, N.J.1
Erdmann, J.2
Hall, A.S.3
-
37
-
-
34250010480
-
A common variant on chromosome 9p21 affects the risk of myocardial infarction
-
Helgadottir A, Thorleifsson G, Manolescu A, et al. A common variant on chromosome 9p21 affects the risk of myocardial infarction. Science. 2007;316:1491-1493.
-
(2007)
Science
, vol.316
, pp. 1491-1493
-
-
Helgadottir, A.1
Thorleifsson, G.2
Manolescu, A.3
-
38
-
-
77951809528
-
Chromosome 9p21 and coronary artery disease
-
McPherson R. Chromosome 9p21 and coronary artery disease. N Engl J Med. 2010;362:1736-1737.
-
(2010)
N Engl J Med
, vol.362
, pp. 1736-1737
-
-
McPherson, R.1
-
39
-
-
33751311529
-
Telomere biology and cardiovascular disease
-
Fuster JJ, Andres V. Telomere biology and cardiovascular disease. Circ Res. 2006;99:1167-1180.
-
(2006)
Circ Res
, vol.99
, pp. 1167-1180
-
-
Fuster, J.J.1
Andres, V.2
-
40
-
-
22944488871
-
Telomeres and human disease: Ageing, cancer and beyond
-
Blasco MA. Telomeres and human disease: Ageing, cancer and beyond. Nat Rev Genet. 2005;6:611-622.
-
(2005)
Nat Rev Genet
, vol.6
, pp. 611-622
-
-
Blasco, M.A.1
-
41
-
-
0029940570
-
Differential expression of telomerase activity in hematopoietic progenitors from adult human bone marrow
-
Chiu CP, Dragowska W, Kim NW, Vaziri H, Yui J, Thomas T, Harley C, Lansdorp P. Differential expression of telomerase activity in hematopoietic progenitors from adult human bone marrow. Stem Cells. 1996; 14:239-248.
-
(1996)
Stem Cells
, vol.14
, pp. 239-248
-
-
Chiu, C.P.1
Dragowska, W.2
Kim, N.W.3
Vaziri, H.4
Yui, J.5
Thomas, T.6
Harley, C.7
Lansdorp, P.8
-
42
-
-
0028856794
-
Telomere length and replicative aging in human vascular tissues
-
Chang E, Harley CB. Telomere length and replicative aging in human vascular tissues. Proc Natl Acad Sci USA. 1995;92:11190-11194.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 11190-11194
-
-
Chang, E.1
Harley, C.B.2
-
43
-
-
3242735506
-
Telomere attrition and accumulation of senescent cells in cultured human endothelial cells
-
Hastings R, Qureshi M, Verma R, Lacy P, Williams B. Telomere attrition and accumulation of senescent cells in cultured human endothelial cells. Cell Prolif. 2004;37:317-324.
-
(2004)
Cell Prolif
, vol.37
, pp. 317-324
-
-
Hastings, R.1
Qureshi, M.2
Verma, R.3
Lacy, P.4
Williams, B.5
-
44
-
-
0035845259
-
Telomere shortening in atherosclerosis
-
Samani NJ, Boultby R, Butler R, Thompson J, Goodall A. Telomere shortening in atherosclerosis. Lancet. 2001;358:472-473.
-
(2001)
Lancet
, vol.358
, pp. 472-473
-
-
Samani, N.J.1
Boultby, R.2
Butler, R.3
Thompson, J.4
Goodall, A.5
-
45
-
-
0037007075
-
Endothelial cell senescence in human atherosclerosis: Role of telomere in endothelial dysfunction
-
Minamino T, Miyauchi H, Yoshida T, Ishida Y, Yoshida H, Komuro I. Endothelial cell senescence in human atherosclerosis: Role of telomere in endothelial dysfunction. Circulation. 2002;105:1541-1544.
-
(2002)
Circulation
, vol.105
, pp. 1541-1544
-
-
Minamino, T.1
Miyauchi, H.2
Yoshida, T.3
Ishida, Y.4
Yoshida, H.5
Komuro, I.6
-
46
-
-
0037081078
-
Decreased B16F10 melanoma growth and impaired vascularization in telomerase-deficient mice with critically short telomeres
-
Franco S, Segura I, Riese HH, et al. Decreased B16F10 melanoma growth and impaired vascularization in telomerase-deficient mice with critically short telomeres. Cancer Res. 2002;62:552-559.
-
(2002)
Cancer Res
, vol.62
, pp. 552-559
-
-
Franco, S.1
Segura, I.2
Riese, H.H.3
-
47
-
-
60349113539
-
Mechanisms of endothelial senescence
-
Erusalimsky JD, Skene C. Mechanisms of endothelial senescence. Exp Physiol. 2009;94:299-304.
-
(2009)
Exp Physiol
, vol.94
, pp. 299-304
-
-
Erusalimsky, J.D.1
Skene, C.2
-
48
-
-
0033543760
-
Human endothelial cell life extension by telomerase expression
-
Yang J, Chang E, Cherry AM, Bangs C, Oei Y, Bodnar A, Bronstein A, Chiu C, Herron G. Human endothelial cell life extension by telomerase expression. J Biol Chem. 1999;274:26141-26148.
-
(1999)
J Biol Chem
, vol.274
, pp. 26141-26148
-
-
Yang, J.1
Chang, E.2
Cherry, A.M.3
Bangs, C.4
Oei, Y.5
Bodnar, A.6
Bronstein, A.7
Chiu, C.8
Herron, G.9
-
49
-
-
0035955754
-
ENOS activity is reduced in senescent human endothelial cells: Preservation by hTERT immortalization
-
Matsushita H, Chang E, Glassford AJ, Cooke J, Chiu C, Tsao P. eNOS activity is reduced in senescent human endothelial cells: Preservation by hTERT immortalization. Circ Res. 2001;89:793-798.
-
(2001)
Circ Res
, vol.89
, pp. 793-798
-
-
Matsushita, H.1
Chang, E.2
Glassford, A.J.3
Cooke, J.4
Chiu, C.5
Tsao, P.6
-
50
-
-
0037183542
-
Constitutive human telomerase reverse transcriptase expression enhances regenerative properties of endothelial progenitor cells
-
Murasawa S, Llevadot J, Silver M, Isner J, Losordo D, Asahara T. Constitutive human telomerase reverse transcriptase expression enhances regenerative properties of endothelial progenitor cells. Circulation. 2002;106:1133-1139.
-
(2002)
Circulation
, vol.106
, pp. 1133-1139
-
-
Murasawa, S.1
Llevadot, J.2
Silver, M.3
Isner, J.4
Losordo, D.5
Asahara, T.6
-
51
-
-
0035108952
-
Telomerized human microvasculature is functional in vivo
-
Yang J, Nagavarapu U, Relloma K, Sjaastad M, Moss W, Passaniti A, Herron G. Telomerized human microvasculature is functional in vivo. Nat Biotechnol. 2001;19:219-224.
-
(2001)
Nat Biotechnol
, vol.19
, pp. 219-224
-
-
Yang, J.1
Nagavarapu, U.2
Relloma, K.3
Sjaastad, M.4
Moss, W.5
Passaniti, A.6
Herron, G.7
-
52
-
-
0037387730
-
Immortalization of bovine capillary endothelial cells by hTERT alone involves inactivation of endogenous p16INK4a/pRb
-
Veitonmaki N, Fuxe J, Hultdin M, Roos G, Pettersson R, Cao Y. Immortalization of bovine capillary endothelial cells by hTERT alone involves inactivation of endogenous p16INK4a/pRb. FASEB J. 2003; 17:764-766.
-
(2003)
FASEB J
, vol.17
, pp. 764-766
-
-
Veitonmaki, N.1
Fuxe, J.2
Hultdin, M.3
Roos, G.4
Pettersson, R.5
Cao, Y.6
-
53
-
-
78650990326
-
Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice
-
Jaskelioff M, Muller FL, Paik JH, Thomas E, Jiang S, Adams AC, Sahin E, Kost-Alimova M, Protopopov A, Cadiñanos J, Horner JW, Maratos-Flier E, DePinho RA. Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice. Nature. 2011;469: 102-106.
-
(2011)
Nature
, vol.469
, pp. 102-106
-
-
Jaskelioff, M.1
Muller, F.L.2
Paik, J.H.3
Thomas, E.4
Jiang, S.5
Adams, A.C.6
Sahin, E.7
Kost-Alimova, M.8
Protopopov, A.9
Cadiñanos, J.10
Horner, J.W.11
Maratos-Flier, E.12
Depinho, R.A.13
-
54
-
-
79951812916
-
Telomere dysfunction induces metabolic and mitochondrial compromise
-
Sahin E, Colla S, Liesa M, et al. Telomere dysfunction induces metabolic and mitochondrial compromise. Nature. 2011;470:359-365.
-
(2011)
Nature
, vol.470
, pp. 359-365
-
-
Sahin, E.1
Colla, S.2
Liesa, M.3
-
55
-
-
22144434964
-
Transcriptional coactivator PGC-1 alpha controls the energy state and contractile function of cardiac muscle
-
Arany Z, He H, Lin J, et al. Transcriptional coactivator PGC-1 alpha controls the energy state and contractile function of cardiac muscle. Cell Metab. 2005;1:259-271.
-
(2005)
Cell Metab
, vol.1
, pp. 259-271
-
-
Arany, Z.1
He, H.2
Lin, J.3
-
56
-
-
33745627066
-
Transverse aortic constriction leads to accelerated heart failure in mice lacking PPAR-gamma coactivator 1alpha
-
Arany Z, Novikov M, Chin S, Ma Y, Rosenzweig A, Spiegelman BM. Transverse aortic constriction leads to accelerated heart failure in mice lacking PPAR-gamma coactivator 1alpha. Proc Natl Acad Sci UthsS A. 2006;103:10086-10091.
-
(2006)
Proc Natl Acad Sci UthsS A
, vol.103
, pp. 10086-10091
-
-
Arany, Z.1
Novikov, M.2
Chin, S.3
Ma, Y.4
Rosenzweig, A.5
Spiegelman, B.M.6
-
57
-
-
80855138775
-
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
-
Baker DJ, Wijshake T, Tchkonia T, LeBrasseur NK, Childs BG, van de Sluis B, Kirkland JL, van Deursen JM. Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders. Nature. 2011;479: 232-236.
-
(2011)
Nature
, vol.479
, pp. 232-236
-
-
Baker, D.J.1
Wijshake, T.2
Tchkonia, T.3
Lebrasseur, N.K.4
Childs, B.G.5
Van De Sluis, B.6
Kirkland, J.L.7
Van Deursen, J.M.8
-
58
-
-
3042761646
-
BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice
-
Baker DJ, Jeganathan KB, Cameron JD, Thompson M, Juneja S, Kopecka A, Kumar R, Jenkins RB, de Groen PC, Roche P, van Deursen JM. BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice. Nat Genet. 2004;36:744-749.
-
(2004)
Nat Genet
, vol.36
, pp. 744-749
-
-
Baker, D.J.1
Jeganathan, K.B.2
Cameron, J.D.3
Thompson, M.4
Juneja, S.5
Kopecka, A.6
Kumar, R.7
Jenkins, R.B.8
De Groen, P.C.9
Roche, P.10
Van Deursen, J.M.11
-
59
-
-
33947492069
-
Aging-associated vascular phenotype in mutant mice with low levels of BubR1
-
Matsumoto T, Baker DJ, d'Uscio LV, Mozammel G, Katusic ZS, van Deursen JM. Aging-associated vascular phenotype in mutant mice with low levels of BubR1. Stroke. 2007;38:1050-1056.
-
(2007)
Stroke
, vol.38
, pp. 1050-1056
-
-
Matsumoto, T.1
Baker, D.J.2
D'Uscio, L.V.3
Mozammel, G.4
Katusic, Z.S.5
Van Deursen, J.M.6
-
60
-
-
34447316414
-
Trends in oxidative aging theories
-
Muller FL, Lustgarten MS, Jang Y, Richardson A, Van Remmen H. Trends in oxidative aging theories. Free Radic Biol Med. 2007;43: 477-503.
-
(2007)
Free Radic Biol Med
, vol.43
, pp. 477-503
-
-
Muller, F.L.1
Lustgarten, M.S.2
Jang, Y.3
Richardson, A.4
Van Remmen, H.5
-
61
-
-
0026023219
-
Hydrogen peroxide release by mitochondria increases during aging
-
Sohal RS, Sohal BH. Hydrogen peroxide release by mitochondria increases during aging. Mech Ageing Dev. 1991;57:187-202.
-
(1991)
Mech Ageing Dev
, vol.57
, pp. 187-202
-
-
Sohal, R.S.1
Sohal, B.H.2
-
62
-
-
77957938682
-
Somatic mutations of mitochondrial DNA in aging and cancer progression
-
Lee HC, Chang CM, Chi CW. Somatic mutations of mitochondrial DNA in aging and cancer progression. Ageing Res Rev. 2010;9(Suppl 1):S47-S58.
-
(2010)
Ageing Res Rev
, vol.9
, Issue.SUPPL. 1
-
-
Lee, H.C.1
Chang, C.M.2
Chi, C.W.3
-
63
-
-
78349297565
-
Oxidative stress and diabetic complications
-
Giacco F, Brownlee M. Oxidative stress and diabetic complications. Circ Res. 2010;107:1058-1070.
-
(2010)
Circ Res
, vol.107
, pp. 1058-1070
-
-
Giacco, F.1
Brownlee, M.2
-
64
-
-
0037076784
-
Aging-induced phenotypic changes and oxidative stress impair coronary arteriolar function
-
Csiszar A, Ungvari Z, Edwards J, Kaminski P, Wolin M, Koller A, Kaley G. Aging-induced phenotypic changes and oxidative stress impair coronary arteriolar function. Circ Res. 2002;90:1159-1166.
-
(2002)
Circ Res
, vol.90
, pp. 1159-1166
-
-
Csiszar, A.1
Ungvari, Z.2
Edwards, J.3
Kaminski, P.4
Wolin, M.5
Koller, A.6
Kaley, G.7
-
65
-
-
73949132134
-
Stimulation of coronary collateral growth by granulocyte stimulating factor: Role of reactive oxygen species
-
Carrao AC, Chilian WM, Yun J, Kolz C, Rocic P, Lehmann K, van den Wijngaard JP, van Horssen P, Spaan JA, Ohanyan V, Pung YF, Buschmann I. Stimulation of coronary collateral growth by granulocyte stimulating factor: Role of reactive oxygen species. Arterioscler Thromb Vasc Biol. 2009;29:1817-1822.
-
(2009)
Arterioscler Thromb Vasc Biol
, vol.29
, pp. 1817-1822
-
-
Carrao, A.C.1
Chilian, W.M.2
Yun, J.3
Kolz, C.4
Rocic, P.5
Lehmann, K.6
Van Den Wijngaard, J.P.7
Van Horssen, P.8
Spaan, J.A.9
Ohanyan, V.10
Pung, Y.F.11
Buschmann, I.12
-
66
-
-
0036954803
-
Novel role of gp91(phox)-containing NAD(P)H oxidase in vascular endothelial growth factorinduced signaling and angiogenesis
-
Ushio-Fukai M, Tang Y, Fukai T, Dikalov SI, Ma Y, Fujimoto M, Quinn MT, Pagano PJ, Johnson C, Alexander RW. Novel role of gp91(phox)-containing NAD(P)H oxidase in vascular endothelial growth factorinduced signaling and angiogenesis. Circ Res. 2002;91:1160-1167.
-
(2002)
Circ Res
, vol.91
, pp. 1160-1167
-
-
Ushio-Fukai, M.1
Tang, Y.2
Fukai, T.3
Dikalov, S.I.4
Ma, Y.5
Fujimoto, M.6
Quinn, M.T.7
Pagano, P.J.8
Johnson, C.9
Alexander, R.W.10
-
67
-
-
18444401175
-
Role of gp91phox (Nox2)-containing NAD(P)H oxidase in angiogenesis in response to hindlimb ischemia
-
Tojo T, Ushio-Fukai M, Yamaoka-Tojo M, Ikeda S, Patrushev N, Alexander RW. Role of gp91phox (Nox2)-containing NAD(P)H oxidase in angiogenesis in response to hindlimb ischemia. Circulation. 2005; 111:2347-2355.
-
(2005)
Circulation
, vol.111
, pp. 2347-2355
-
-
Tojo, T.1
Ushio-Fukai, M.2
Yamaoka-Tojo, M.3
Ikeda, S.4
Patrushev, N.5
Alexander, R.W.6
-
68
-
-
5544237716
-
Reactive oxygen species as mediators of angiogenesis signaling: Role of NAD(P)H oxidase
-
Ushio-Fukai M, Alexander RW. Reactive oxygen species as mediators of angiogenesis signaling: Role of NAD(P)H oxidase. Mol Cell Biochem. 2004;264:85-97.
-
(2004)
Mol Cell Biochem
, vol.264
, pp. 85-97
-
-
Ushio-Fukai, M.1
Alexander, R.W.2
-
69
-
-
0035140553
-
Superoxide anions and endothelial cell proliferation in normoglycemia and hyperglycemia
-
Zanetti M, Zwacka R, Engelhardt J, Katusic Z, O'Brien T. Superoxide anions and endothelial cell proliferation in normoglycemia and hyperglycemia. Arterioscler Thromb Vasc Biol. 2001;21:195-200.
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 195-200
-
-
Zanetti, M.1
Zwacka, R.2
Engelhardt, J.3
Katusic, Z.4
O'Brien, T.5
-
70
-
-
24344499139
-
Hydrogen peroxide regulation of endothelial function: Origins, mechanisms, and consequences
-
Cai H. Hydrogen peroxide regulation of endothelial function: Origins, mechanisms, and consequences. Cardiovasc Res. 2005;68:26-36.
-
(2005)
Cardiovasc Res
, vol.68
, pp. 26-36
-
-
Cai, H.1
-
71
-
-
3042591085
-
Chronic oxidative stress compromises telomere integrity and accelerates the onset of senescence in human endothelial cells
-
Kurz DJ, Decary S, Hong Y, Trivier E, Akhmedov A, Erusalimsky J. Chronic oxidative stress compromises telomere integrity and accelerates the onset of senescence in human endothelial cells. J Cell Sci. 2004; 117:2417-2426.
-
(2004)
J Cell Sci
, vol.117
, pp. 2417-2426
-
-
Kurz, D.J.1
Decary, S.2
Hong, Y.3
Trivier, E.4
Akhmedov, A.5
Erusalimsky, J.6
-
72
-
-
0034688195
-
Vitamin e supplementation and cardiovascular events in high-risk patients. the heart outcomes prevention evaluation study investigators
-
Yusuf S, Dagenais G, Pogue J, Bosch J, Sleight P. Vitamin E supplementation and cardiovascular events in high-risk patients. The heart outcomes prevention evaluation study investigators. N Engl J Med. 2000;342:154-160.
-
(2000)
N Engl J Med
, vol.342
, pp. 154-160
-
-
Yusuf, S.1
Dagenais, G.2
Pogue, J.3
Bosch, J.4
Sleight, P.5
-
73
-
-
56149111693
-
Vitamins e and C in the prevention of cardiovascular disease in men: The physicians' health study II randomized controlled trial
-
Sesso HD, Buring JE, Christen WG, Kurth T, Belanger C, MacFadyen J, Bubes V, Manson J, Glynn R, Gaziano J. Vitamins E and C in the prevention of cardiovascular disease in men: The physicians' health study II randomized controlled trial. JAMA. 2008;300:2123-2133.
-
(2008)
JAMA
, vol.300
, pp. 2123-2133
-
-
Sesso, H.D.1
Buring, J.E.2
Christen, W.G.3
Kurth, T.4
Belanger, C.5
MacFadyen, J.6
Bubes, V.7
Manson, J.8
Glynn, R.9
Gaziano, J.10
-
74
-
-
34247895799
-
Endothelial-specific expression of mitochondrial thioredoxin improves endothelial cell function and reduces atherosclerotic lesions
-
Zhang H, Luo Y, Zhang W, He Y, Dai S, Zhang R, Huang Y, Bernatchez P, Giordano F, Shadel G, Sessa W, Min W. Endothelial-specific expression of mitochondrial thioredoxin improves endothelial cell function and reduces atherosclerotic lesions. Am J Pathol. 2007;170: 1108-1120.
-
(2007)
Am J Pathol
, vol.170
, pp. 1108-1120
-
-
Zhang, H.1
Luo, Y.2
Zhang, W.3
He, Y.4
Dai, S.5
Zhang, R.6
Huang, Y.7
Bernatchez, P.8
Giordano, F.9
Shadel, G.10
Sessa, W.11
Min, W.12
-
75
-
-
0032493742
-
Age-dependent telomere shortening is slowed down by enrichment of intracellular vitamin C via suppression of oxidative stress
-
Furumoto K, Inoue E, Nagao N, Hiyama E, Miwa N. Age-dependent telomere shortening is slowed down by enrichment of intracellular vitamin C via suppression of oxidative stress. Life Sci. 1998;63: 935-948.
-
(1998)
Life Sci
, vol.63
, pp. 935-948
-
-
Furumoto, K.1
Inoue, E.2
Nagao, N.3
Hiyama, E.4
Miwa, N.5
-
76
-
-
1842611977
-
Antioxidants inhibit nuclear export of telomerase reverse transcriptase and delay replicative senescence of endothelial cells
-
Haendeler J, Hoffmann J, Diehl JF, Vasa M, Spyridopoulos I, Zeiher A, Dimmeler S. Antioxidants inhibit nuclear export of telomerase reverse transcriptase and delay replicative senescence of endothelial cells. Circ Res. 2004;94:768-775.
-
(2004)
Circ Res
, vol.94
, pp. 768-775
-
-
Haendeler, J.1
Hoffmann, J.2
Diehl, J.F.3
Vasa, M.4
Spyridopoulos, I.5
Zeiher, A.6
Dimmeler, S.7
-
77
-
-
23044438492
-
Aspirin reduces endothelial cell senescence
-
Bode-Boger SM, Martens-Lobenhoffer J, Tager M, Schroder H, Scalera F. Aspirin reduces endothelial cell senescence. Biochem Biophys Res Commun. 2005;334:1226-1232.
-
(2005)
Biochem Biophys Res Commun
, vol.334
, pp. 1226-1232
-
-
Bode-Boger, S.M.1
Martens-Lobenhoffer, J.2
Tager, M.3
Schroder, H.4
Scalera, F.5
-
78
-
-
1642545080
-
Vitamin C improves attenuated angiotensin II-induced endotheliumdependent vasodilation in human forearm vessels
-
Hirooka Y, Eshima K, Setoguchi S, Kishi T, Egashira K, Takeshita A. Vitamin C improves attenuated angiotensin II-induced endotheliumdependent vasodilation in human forearm vessels. Hypertens Res. 2003; 26:953-959.
-
(2003)
Hypertens Res
, vol.26
, pp. 953-959
-
-
Hirooka, Y.1
Eshima, K.2
Setoguchi, S.3
Kishi, T.4
Egashira, K.5
Takeshita, A.6
-
79
-
-
0033581704
-
The p66shc adaptor protein controls oxidative stress response and life span in mammals
-
Migliaccio E, Giorgio M, Mele S, Pelicci G, Reboldi P, Pandolfi P, Lanfrancone L, Pelicci P. The p66shc adaptor protein controls oxidative stress response and life span in mammals. Nature. 1999;402:309-313.
-
(1999)
Nature
, vol.402
, pp. 309-313
-
-
Migliaccio, E.1
Giorgio, M.2
Mele, S.3
Pelicci, G.4
Reboldi, P.5
Pandolfi, P.6
Lanfrancone, L.7
Pelicci, P.8
-
80
-
-
80052580047
-
Repression of P66Shc expression by SIRT1 contributes to the prevention of hyperglycemia-induced endothelial dysfunction
-
Zhou S, Chen HZ, Wan YZ, Zhang QJ, Wei YS, Huang S, Liu JJ, Lu YB, Zhang ZQ, Yang RF, Zhang R, Cai H, Liu DP, Liang CC. Repression of P66Shc expression by SIRT1 contributes to the prevention of hyperglycemia-induced endothelial dysfunction. Circ Res. 2011;109:639-648.
-
(2011)
Circ Res
, vol.109
, pp. 639-648
-
-
Zhou, S.1
Chen, H.Z.2
Wan, Y.Z.3
Zhang, Q.J.4
Wei, Y.S.5
Huang, S.6
Liu, J.J.7
Lu, Y.B.8
Zhang, Z.Q.9
Yang, R.F.10
Zhang, R.11
Cai, H.12
Liu, D.P.13
Liang, C.C.14
-
81
-
-
8144229685
-
Deletion of p66shc gene protects against age-related endothelial dysfunction
-
Francia P, delli Gatti C, Bachschmid M, Martin-Padura I, Savoia C, Migliaccio E, Pelicci PG, Schiavoni M, Luscher TF, Volpe M, Cosentino F. Deletion of p66shc gene protects against age-related endothelial dysfunction. Circulation. 2004;110:2889-2895.
-
(2004)
Circulation
, vol.110
, pp. 2889-2895
-
-
Francia, P.1
Delli Gatti, C.2
Bachschmid, M.3
Martin-Padura, I.4
Savoia, C.5
Migliaccio, E.6
Pelicci, P.G.7
Schiavoni, M.8
Luscher, T.F.9
Volpe, M.10
Cosentino, F.11
-
82
-
-
0037452461
-
Deletion of the p66shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet
-
Napoli C, Martin-Padura I, de Nigris F, Giorgio M, Mansueto G, Somma P, Condorelli M, Sica G, De Rosa G, Pelicci P. Deletion of the p66shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet. Proc Natl Acad Sci USA. 2003;100:2112-2116.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 2112-2116
-
-
Napoli, C.1
Martin-Padura, I.2
De Nigris, F.3
Giorgio, M.4
Mansueto, G.5
Somma, P.6
Condorelli, M.7
Sica, G.8
De Rosa, G.9
Pelicci, P.10
-
83
-
-
27644570778
-
P66shc regulates endothelial NO production and endothelium-dependent vasorelaxation: Implications for age-associated vascular dysfunction
-
Yamamori T, White AR, Mattagajasingh I, Khanday FA, Haile A, Qi B, Jeon BH, Bugayenko A, Kasuno K, Berkowitz DE, Irani K. P66shc regulates endothelial NO production and endothelium-dependent vasorelaxation: Implications for age-associated vascular dysfunction. J Mol Cell Cardiol. 2005;39:992-995.
-
(2005)
J Mol Cell Cardiol
, vol.39
, pp. 992-995
-
-
Yamamori, T.1
White, A.R.2
Mattagajasingh, I.3
Khanday, F.A.4
Haile, A.5
Qi, B.6
Jeon, B.H.7
Bugayenko, A.8
Kasuno, K.9
Berkowitz, D.E.10
Irani, K.11
-
84
-
-
0032102292
-
Nitric oxide synthase modulates angiogenesis in response to tissue ischemia
-
Murohara T, Asahara T, Silver M, Bauters C, Masuda H, Kalka C, Kearney M, Chen D, Symes J, Fishman M, Huang P, Isner J. Nitric oxide synthase modulates angiogenesis in response to tissue ischemia. J Clin Invest. 1998;101:2567-2578.
-
(1998)
J Clin Invest
, vol.101
, pp. 2567-2578
-
-
Murohara, T.1
Asahara, T.2
Silver, M.3
Bauters, C.4
Masuda, H.5
Kalka, C.6
Kearney, M.7
Chen, D.8
Symes, J.9
Fishman, M.10
Huang, P.11
Isner, J.12
-
85
-
-
2642597076
-
Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells
-
Papapetropoulos A, Garcia-Cardena G, Madri JA, Sessa W. Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells. J Clin Invest. 1997;100: 3131-3139.
-
(1997)
J Clin Invest
, vol.100
, pp. 3131-3139
-
-
Papapetropoulos, A.1
Garcia-Cardena, G.2
Madri, J.A.3
Sessa, W.4
-
86
-
-
27144490382
-
Nitric oxide differentially regulates proliferation and mobilization of endothelial progenitor cells but not of hematopoietic stem cells
-
Ozuyaman B, Ebner P, Niesler U, Ziemann J, Kleinbongard P, Jax T, Godecke A, Kelm M, Kalka C. Nitric oxide differentially regulates proliferation and mobilization of endothelial progenitor cells but not of hematopoietic stem cells. Thromb Haemost. 2005;94:770-772.
-
(2005)
Thromb Haemost
, vol.94
, pp. 770-772
-
-
Ozuyaman, B.1
Ebner, P.2
Niesler, U.3
Ziemann, J.4
Kleinbongard, P.5
Jax, T.6
Godecke, A.7
Kelm, M.8
Kalka, C.9
-
87
-
-
0035941411
-
Shear stress regulates endothelial nitric oxide synthase expression through c-Src by divergent signaling pathways
-
Davis ME, Cai H, Drummond GR, Harrison D. Shear stress regulates endothelial nitric oxide synthase expression through c-Src by divergent signaling pathways. Circ Res. 2001;89:1073-1080.
-
(2001)
Circ Res
, vol.89
, pp. 1073-1080
-
-
Davis, M.E.1
Cai, H.2
Drummond, G.R.3
Harrison, D.4
-
88
-
-
33750944018
-
Endothelial cellular senescence is inhibited by nitric oxide: Implications in atherosclerosis associated with menopause and diabetes
-
Hayashi T, Matsui-Hirai H, Miyazaki-Akita A, Fukatsu A, Funami J, Ding Q, Kamalanathan S, Hattori Y, Ignarro L, Iguchi A. Endothelial cellular senescence is inhibited by nitric oxide: Implications in atherosclerosis associated with menopause and diabetes. Proc Natl Acad Sci USA. 2006;103:17018-17023.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 17018-17023
-
-
Hayashi, T.1
Matsui-Hirai, H.2
Miyazaki-Akita, A.3
Fukatsu, A.4
Funami, J.5
Ding, Q.6
Kamalanathan, S.7
Hattori, Y.8
Ignarro, L.9
Iguchi, A.10
-
89
-
-
62649123264
-
Endothelial function and oxidative stress in cardiovascular diseases
-
Higashi Y, Noma K, Yoshizumi M, Kihara Y. Endothelial function and oxidative stress in cardiovascular diseases. Circ J. 2009;73:411-418.
-
(2009)
Circ J
, vol.73
, pp. 411-418
-
-
Higashi, Y.1
Noma, K.2
Yoshizumi, M.3
Kihara, Y.4
-
90
-
-
84855858922
-
Nitric oxide synthases: Regulation and function
-
Sep 1. [Epub ahead of print]
-
Forstermann U, Sessa W. Nitric oxide synthases: Regulation and function. Eur Heart J. 2011 Sep 1. [Epub ahead of print].
-
(2011)
Eur Heart J
-
-
Forstermann, U.1
Sessa, W.2
-
91
-
-
3042730959
-
ENOS at a glance
-
Sessa WC. eNOS at a glance. J Cell Sci. 2004;117:2427-2429.
-
(2004)
J Cell Sci
, vol.117
, pp. 2427-2429
-
-
Sessa, W.C.1
-
92
-
-
0030774840
-
Anatomic heterogeneity of vascular aging: Role of nitric oxide and endothelin
-
Barton M, Cosentino F, Brandes RP, Moreau P, Shaw S, Luscher T. Anatomic heterogeneity of vascular aging: Role of nitric oxide and endothelin. Hypertension. 1997;30:817-824.
-
(1997)
Hypertension
, vol.30
, pp. 817-824
-
-
Barton, M.1
Cosentino, F.2
Brandes, R.P.3
Moreau, P.4
Shaw, S.5
Luscher, T.6
-
93
-
-
77249166529
-
Alterations in the activity and expression of endothelial NO synthase in aged human endothelial cells
-
Yoon HJ, Cho SW, Ahn BW, Yang S. Alterations in the activity and expression of endothelial NO synthase in aged human endothelial cells. Mech Ageing Dev. 2010;131:119-123.
-
(2010)
Mech Ageing Dev
, vol.131
, pp. 119-123
-
-
Yoon, H.J.1
Cho, S.W.2
Ahn, B.W.3
Yang, S.4
-
94
-
-
70350117109
-
Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats
-
Kim JH, Bugaj LJ, Oh YJ, et al. Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats. J Appl Physiol. 2009;107:1249-1257.
-
(2009)
J Appl Physiol
, vol.107
, pp. 1249-1257
-
-
Kim, J.H.1
Bugaj, L.J.2
Oh, Y.J.3
-
95
-
-
33748288089
-
Age-related changes in endothelial nitric oxide synthase phosphorylation and nitric oxide dependent vasodilation: Evidence for a novel mechanism involving sphingomyelinase and ceramide-activated phosphatase 2A
-
Smith AR, Visioli F, Frei B, Hagen T. Age-related changes in endothelial nitric oxide synthase phosphorylation and nitric oxide dependent vasodilation: Evidence for a novel mechanism involving sphingomyelinase and ceramide-activated phosphatase 2A. Aging Cell. 2006;5: 391-400.
-
(2006)
Aging Cell
, vol.5
, pp. 391-400
-
-
Smith, A.R.1
Visioli, F.2
Frei, B.3
Hagen, T.4
-
96
-
-
13944274915
-
Defects in activation of nitric oxide synthases occur during delayed angiogenesis in aging
-
Bach MH, Sadoun E, Reed MJ. Defects in activation of nitric oxide synthases occur during delayed angiogenesis in aging. Mech Ageing Dev. 2005;126:467-473.
-
(2005)
Mech Ageing Dev
, vol.126
, pp. 467-473
-
-
Bach, M.H.1
Sadoun, E.2
Reed, M.J.3
-
97
-
-
68149183625
-
Effects of ageing and exercise training on eNOS uncoupling in skeletal muscle resistance arterioles
-
Sindler AL, Delp MD, Reyes R, Wu G, Muller-Delp J. Effects of ageing and exercise training on eNOS uncoupling in skeletal muscle resistance arterioles. J Physiol. 2009;587:3885-3897.
-
(2009)
J Physiol
, vol.587
, pp. 3885-3897
-
-
Sindler, A.L.1
Delp, M.D.2
Reyes, R.3
Wu, G.4
Muller-Delp, J.5
-
98
-
-
70350459448
-
Sun D. eNOS uncoupling and endothelial dysfunction in aged vessels
-
Yang YM, Huang A, Kaley G, Sun D. eNOS uncoupling and endothelial dysfunction in aged vessels. Am J Physiol Heart Circ Physiol. 2009; 297:H1829-H1836.
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.297
-
-
Yang, Y.M.1
Huang, A.2
Kaley, G.3
-
99
-
-
0034684652
-
Enhanced peroxynitrite formation is associated with vascular aging
-
van der Loo B, Labugger R, Skepper JN, Bachschmid M, Kilo J, Powell JM, Palacios-Callender M, Erusalimsky JD, Quaschning T, Malinski T, Gygi D, Ullrich V, Lüscher TF. Enhanced peroxynitrite formation is associated with vascular aging. J Exp Med. 2000;192:1731-1744.
-
(2000)
J Exp Med
, vol.192
, pp. 1731-1744
-
-
Van Der Loo, B.1
Labugger, R.2
Skepper, J.N.3
Bachschmid, M.4
Kilo, J.5
Powell, J.M.6
Palacios-Callender, M.7
Erusalimsky, J.D.8
Quaschning, T.9
Malinski, T.10
Gygi, D.11
Ullrich, V.12
Lüscher, T.F.13
-
100
-
-
0025189864
-
Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide
-
Beckman J, Beckman T, Chen J, Marshall P, Freeman B. Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide. Proc Natl Acad Sci USA. 1990;87:1620-1624.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 1620-1624
-
-
Beckman, J.1
Beckman, T.2
Chen, J.3
Marshall, P.4
Freeman, B.5
-
101
-
-
0032482975
-
Superoxide generation by endothelial nitric oxide synthase: The influence of cofactors
-
Vasquez-Vivar J, Kalyanaraman B, Martasek P, Hogg N, Masters B, Karoui H, Tordo P, Pritchard KJ. Superoxide generation by endothelial nitric oxide synthase: The influence of cofactors. Proc Natl Acad Sci USA. 1998;95:9220-9225.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 9220-9225
-
-
Vasquez-Vivar, J.1
Kalyanaraman, B.2
Martasek, P.3
Hogg, N.4
Masters, B.5
Karoui, H.6
Tordo, P.7
Pritchard, K.J.8
-
102
-
-
0031886546
-
Alterations of nitric oxide synthase expression with aging and hypertension in rats
-
Chou TC, Yen MH, Li CY, Ding Y. Alterations of nitric oxide synthase expression with aging and hypertension in rats. Hypertension. 1998;31: 643-648.
-
(1998)
Hypertension
, vol.31
, pp. 643-648
-
-
Chou, T.C.1
Yen, M.H.2
Li, C.Y.3
Ding, Y.4
-
103
-
-
0034703017
-
Age-dependent defect in vascular endothelial growth factor expression is associated with reduced hypoxia-inducible factor 1 activity
-
Rivard A, Berthou-Soulie L, Principe N, Kearney M, Curry C, Branellec D, Semenza GL, Isner JM. Age-dependent defect in vascular endothelial growth factor expression is associated with reduced hypoxia-inducible factor 1 activity. J Biol Chem. 2000;275:29643-29647.
-
(2000)
J Biol Chem
, vol.275
, pp. 29643-29647
-
-
Rivard, A.1
Berthou-Soulie, L.2
Principe, N.3
Kearney, M.4
Curry, C.5
Branellec, D.6
Semenza, G.L.7
Isner, J.M.8
-
104
-
-
77955914268
-
Impaired angiogenesis in aging myocardial microvascular endothelial cells is associated with reduced importin alpha and decreased nuclear transport of HIF1 alpha: Mechanistic implications
-
Ahluwalia A, Narula J, Jones MK, Deng X, Tarnawski A. Impaired angiogenesis in aging myocardial microvascular endothelial cells is associated with reduced importin alpha and decreased nuclear transport of HIF1 alpha: Mechanistic implications. J Physiol Pharmacol. 2010; 61:133-139.
-
(2010)
J Physiol Pharmacol
, vol.61
, pp. 133-139
-
-
Ahluwalia, A.1
Narula, J.2
Jones, M.K.3
Deng, X.4
Tarnawski, A.5
-
105
-
-
33947727879
-
Use of a constitutively active hypoxia-inducible factor-1alpha transgene as a therapeutic strategy in no-option critical limb ischemia patients: Phase i doseescalation experience
-
Rajagopalan S, Olin J, Deitcher S, Pieczek A, Laird J, Grossman P, Goldman C, McEllin K, Kelly R, Chronos N. Use of a constitutively active hypoxia-inducible factor-1alpha transgene as a therapeutic strategy in no-option critical limb ischemia patients: Phase I doseescalation experience. Circulation. 2007;115:1234-1243.
-
(2007)
Circulation
, vol.115
, pp. 1234-1243
-
-
Rajagopalan, S.1
Olin, J.2
Deitcher, S.3
Pieczek, A.4
Laird, J.5
Grossman, P.6
Goldman, C.7
McEllin, K.8
Kelly, R.9
Chronos, N.10
-
106
-
-
37349115260
-
Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemia
-
Bosch-Marce M, Okuyama H, Wesley JB, et al. Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemia. Circ Res. 2007;101: 1310-1318.
-
(2007)
Circ Res
, vol.101
, pp. 1310-1318
-
-
Bosch-Marce, M.1
Okuyama, H.2
Wesley, J.B.3
-
107
-
-
77955985342
-
Exercise training stimulates ischemia-induced neovascularizat ion via phosphatidylinositol 3-kinase/Akt-dependent hypoxia-induced factor-1 alpha reactivation in mice of advanced age
-
Cheng XW, Kuzuya M, Kim W, Song H, Hu L, Inoue A, Nakamura K, Di Q, Sasaki T, Tsuzuki M, Shi G, Okumura K, Murohara T. Exercise training stimulates ischemia-induced neovascularizat ion via phosphatidylinositol 3-kinase/Akt-dependent hypoxia-induced factor-1 alpha reactivation in mice of advanced age. Circulation. 2010;122:707-716.
-
(2010)
Circulation
, vol.122
, pp. 707-716
-
-
Cheng, X.W.1
Kuzuya, M.2
Kim, W.3
Song, H.4
Hu, L.5
Inoue, A.6
Nakamura, K.7
Di, Q.8
Sasaki, T.9
Tsuzuki, M.10
Shi, G.11
Okumura, K.12
Murohara, T.13
-
108
-
-
77953271453
-
Endogenous glucocorticoids decrease skeletal angiogenesis, vascularity, hydration, and strength in aged mice
-
Weinstein RS, Wan C, Liu Q, Wang Y, Almeida M, O'Brien C, Thostenson J, Roberson P, Boskey A, Clemens T, Manolagas S. Endogenous glucocorticoids decrease skeletal angiogenesis, vascularity, hydration, and strength in aged mice. Aging Cell. 2010;9:147-161.
-
(2010)
Aging Cell
, vol.9
, pp. 147-161
-
-
Weinstein, R.S.1
Wan, C.2
Liu, Q.3
Wang, Y.4
Almeida, M.5
O'Brien, C.6
Thostenson, J.7
Roberson, P.8
Boskey, A.9
Clemens, T.10
Manolagas, S.11
-
109
-
-
77955499804
-
Sirtuin 1 modulates cellular responses to hypoxia by deacetylating hypoxia-inducible factor 1alpha
-
Lim JH, Lee YM, Chun YS, Chen J, Kim J, Park J. Sirtuin 1 modulates cellular responses to hypoxia by deacetylating hypoxia-inducible factor 1alpha. Mol Cell. 2010;38:864-878.
-
(2010)
Mol Cell
, vol.38
, pp. 864-878
-
-
Lim, J.H.1
Lee, Y.M.2
Chun, Y.S.3
Chen, J.4
Kim, J.5
Park, J.6
-
110
-
-
72249119811
-
VEGF-A: A critical regulator of blood vessel growth
-
Ferrara N. VEGF-A: A critical regulator of blood vessel growth. Eur Cytokine Netw. 2009;20:158-163.
-
(2009)
Eur Cytokine Netw
, vol.20
, pp. 158-163
-
-
Ferrara, N.1
-
112
-
-
29744467229
-
Effect of aging on expression of angiogenesis-related factors in mouse skeletal muscle
-
Wagatsuma A. Effect of aging on expression of angiogenesis-related factors in mouse skeletal muscle. Exp Gerontol. 2006;41:49-54.
-
(2006)
Exp Gerontol
, vol.41
, pp. 49-54
-
-
Wagatsuma, A.1
-
113
-
-
33644828312
-
Lower skeletal muscle capillarization and VEGF expression in aged vs. young men
-
Ryan NA, Zwetsloot KA, Westerkamp LM, et al. Lower skeletal muscle capillarization and VEGF expression in aged vs. young men. J Appl Physiol. 2006;100:178-185.
-
(2006)
J Appl Physiol
, vol.100
, pp. 178-185
-
-
Ryan, N.A.1
Zwetsloot, K.A.2
Westerkamp, L.M.3
-
114
-
-
27544448565
-
Lower capillarization, VEGF protein, and VEGF mRNA response to acute exercise in the vastus lateralis muscle of aged vs. Young women
-
Croley AN, Zwetsloot KA, Westerkamp LM, Ryan N, Pendergast A, Hickner R, Pofahl W, Gavin T. Lower capillarization, VEGF protein, and VEGF mRNA response to acute exercise in the vastus lateralis muscle of aged vs. Young women. J Appl Physiol. 2005;99:1872-1879.
-
(2005)
J Appl Physiol
, vol.99
, pp. 1872-1879
-
-
Croley, A.N.1
Zwetsloot, K.A.2
Westerkamp, L.M.3
Ryan, N.4
Pendergast, A.5
Hickner, R.6
Pofahl, W.7
Gavin, T.8
-
115
-
-
1642313769
-
Senescent impairment in synergistic cytokine pathways that provide rapid cardioprotection in the rat heart
-
Xaymardan M, Zheng J, Duignan I, Chin A, Holm J, Ballard V, Edelberg J. Senescent impairment in synergistic cytokine pathways that provide rapid cardioprotection in the rat heart. J Exp Med. 2004;199: 797-804.
-
(2004)
J Exp Med
, vol.199
, pp. 797-804
-
-
Xaymardan, M.1
Zheng, J.2
Duignan, I.3
Chin, A.4
Holm, J.5
Ballard, V.6
Edelberg, J.7
-
116
-
-
0029758451
-
FGF-1-dependent proliferative and migratory responses are impaired in senescent human umbilical vein endothelial cells and correlate with the inability to signal tyrosine phosphorylation of fibroblast growth factor receptor-1 substrates
-
Garfinkel S, Hu X, Prudovsky IA, McMahon G, Kapnik E, McDowell S, Maciag T. FGF-1-dependent proliferative and migratory responses are impaired in senescent human umbilical vein endothelial cells and correlate with the inability to signal tyrosine phosphorylation of fibroblast growth factor receptor-1 substrates. J Cell Biol. 1996;134: 783-791.
-
(1996)
J Cell Biol
, vol.134
, pp. 783-791
-
-
Garfinkel, S.1
Hu, X.2
Prudovsky, I.A.3
McMahon, G.4
Kapnik, E.5
McDowell, S.6
MacIag, T.7
-
117
-
-
33748436537
-
Exercise training improves aging-induced downregulation of vegf angiogenic signaling cascade in hearts
-
Iemitsu M. Exercise training improves aging-induced downregulation of vegf angiogenic signaling cascade in hearts. AJP Heart Circ Physiol. 2006;291:H1290-H1298.
-
(2006)
AJP Heart Circ Physiol
, vol.291
-
-
Iemitsu, M.1
-
118
-
-
34447515836
-
Prior exercise improves agedependent vascular endothelial growth factor downregulation and angiogenesis responses to hind-limb ischemia in old rats
-
Leosco D, Rengo G, Iaccarino G, et al. Prior exercise improves agedependent vascular endothelial growth factor downregulation and angiogenesis responses to hind-limb ischemia in old rats. J Gerontol A Biol Sci Med Sci. 2007;62:471-480.
-
(2007)
J Gerontol A Biol Sci Med Sci
, vol.62
, pp. 471-480
-
-
Leosco, D.1
Rengo, G.2
Iaccarino, G.3
-
119
-
-
67949102053
-
Recent progress in the biology and physiology of sirtuins
-
Finkel T, Deng CX, Mostoslavsky R. Recent progress in the biology and physiology of sirtuins. Nature. 2009;460:587-591.
-
(2009)
Nature
, vol.460
, pp. 587-591
-
-
Finkel, T.1
Deng, C.X.2
Mostoslavsky, R.3
-
120
-
-
77949887506
-
Mammalian sirtuins: Biological insights and disease relevance
-
Haigis MC, Sinclair DA. Mammalian sirtuins: Biological insights and disease relevance. Annu Rev Pathol. 2010;5:253-295.
-
(2010)
Annu Rev Pathol
, vol.5
, pp. 253-295
-
-
Haigis, M.C.1
Sinclair, D.A.2
-
121
-
-
0035826271
-
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
-
Tissenbaum HA, Guarente L. Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature. 2001;410:227-230.
-
(2001)
Nature
, vol.410
, pp. 227-230
-
-
Tissenbaum, H.A.1
Guarente, L.2
-
122
-
-
80053134340
-
Regulation of Caenorhabditis elegans lifespan by sir-2.1 transgenes
-
Viswanathan M, Guarente L. Regulation of Caenorhabditis elegans lifespan by sir-2.1 transgenes. Nature. 2011;477:E1-E2.
-
(2011)
Nature
, vol.477
-
-
Viswanathan, M.1
Guarente, L.2
-
123
-
-
33751072349
-
Resveratrol improves health and survival of mice on a high-calorie diet
-
Baur JA, Pearson KJ, Price NL, et al. Resveratrol improves health and survival of mice on a high-calorie diet. Nature. 2006;444:337-342.
-
(2006)
Nature
, vol.444
, pp. 337-342
-
-
Baur, J.A.1
Pearson, K.J.2
Price, N.L.3
-
124
-
-
3943071801
-
Sirtuin activators mimic caloric restriction and delay ageing in metazoans
-
Wood JG, Rogina B, Lavu S, Howitz K, Helfand S, Tatar M, Sinclair D. Sirtuin activators mimic caloric restriction and delay ageing in metazoans. Nature. 2004;430:686-689.
-
(2004)
Nature
, vol.430
, pp. 686-689
-
-
Wood, J.G.1
Rogina, B.2
Lavu, S.3
Howitz, K.4
Helfand, S.5
Tatar, M.6
Sinclair, D.7
-
125
-
-
0141719702
-
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
-
Howitz KT, Bitterman KJ, Cohen HY, Lamming D, Lavu S, Wood J, Zipkin R, Chung P, Kisielewski A, Zhang L, Scherer B, Sinclair D. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature. 2003;425:191-196.
-
(2003)
Nature
, vol.425
, pp. 191-196
-
-
Howitz, K.T.1
Bitterman, K.J.2
Cohen, H.Y.3
Lamming, D.4
Lavu, S.5
Wood, J.6
Zipkin, R.7
Chung, P.8
Kisielewski, A.9
Zhang, L.10
Scherer, B.11
Sinclair, D.12
-
126
-
-
80053168829
-
Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila
-
Burnett C, Valentini S, Cabreiro F, et al. Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila. Nature. 2011; 477:482-485.
-
(2011)
Nature
, vol.477
, pp. 482-485
-
-
Burnett, C.1
Valentini, S.2
Cabreiro, F.3
-
127
-
-
79951881254
-
Protective roles of SIRT1 in atherosclerosis
-
Stein S, Matter CM. Protective roles of SIRT1 in atherosclerosis. Cell Cycle. 2011;10:640-647.
-
(2011)
Cell Cycle
, vol.10
, pp. 640-647
-
-
Stein, S.1
Matter, C.M.2
-
128
-
-
35349011597
-
Sirt1 modulates premature senescence-like phenotype in human endothelial cells
-
Ota H, Akishita M, Eto M, Iijima K, Kaneki M, Ouchi Y. Sirt1 modulates premature senescence-like phenotype in human endothelial cells. J Mol Cell Cardiol. 2007;43:571-579.
-
(2007)
J Mol Cell Cardiol
, vol.43
, pp. 571-579
-
-
Ota, H.1
Akishita, M.2
Eto, M.3
Iijima, K.4
Kaneki, M.5
Ouchi, Y.6
-
129
-
-
26844558334
-
Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS
-
Nisoli E, Tonello C, Cardile A, Cozzi V, Bracale R, Tedesco L, Falcone S, Valerio A, Cantoni O, Clementi E, Moncada S, Carruba MO. Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS. Science. 2005;310:314-317.
-
(2005)
Science
, vol.310
, pp. 314-317
-
-
Nisoli, E.1
Tonello, C.2
Cardile, A.3
Cozzi, V.4
Bracale, R.5
Tedesco, L.6
Falcone, S.7
Valerio, A.8
Cantoni, O.9
Clementi, E.10
Moncada, S.11
Carruba, M.O.12
-
130
-
-
35549008884
-
SIRT1 promotes endotheliumdependent vascular relaxation by activating endothelial nitric oxide synthase
-
Mattagajasingh I, Kim CS, Naqvi A, Yamamori T, Hoffman TA, Jung S-B, DeRicco J, Kasuno K, Irani K. SIRT1 promotes endotheliumdependent vascular relaxation by activating endothelial nitric oxide synthase. Proc Natl Acad Sci USA. 2007;104:14855-14860.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 14855-14860
-
-
Mattagajasingh, I.1
Kim, C.S.2
Naqvi, A.3
Yamamori, T.4
Hoffman, T.A.5
Jung, S.-B.6
Dericco, J.7
Kasuno, K.8
Irani, K.9
-
131
-
-
54149103338
-
Endothelium-specific overexpression of class III deacetylase SIRT1 decreases atherosclerosis in apolipoprotein E-deficient mice
-
Zhang QJ, Wang Z, Chen HZ, Zhou S, Zheng W, Liu G, Wei Y-S, Cai H, Liu D-P, Liang C-C. Endothelium-specific overexpression of class III deacetylase SIRT1 decreases atherosclerosis in apolipoprotein E-deficient mice. Cardiovasc Res. 2008;80:191-199.
-
(2008)
Cardiovasc Res
, vol.80
, pp. 191-199
-
-
Zhang, Q.J.1
Wang, Z.2
Chen, H.Z.3
Zhou, S.4
Zheng, W.5
Liu, G.6
Wei, Y.-S.7
Cai, H.8
Liu, D.-P.9
Liang, C.-C.10
-
132
-
-
82955169641
-
Proatherogenic abnormalities of lipid metabolism in SirT1 transgenic mice are mediated through Creb deacetylation
-
Qiang L, Lin HV, Kim-Muller JY, Welch CL, Gu W, Accili D. Proatherogenic abnormalities of lipid metabolism in SirT1 transgenic mice are mediated through Creb deacetylation. Cell Metab. 2011;14: 758-767.
-
(2011)
Cell Metab
, vol.14
, pp. 758-767
-
-
Qiang, L.1
Lin, H.V.2
Kim-Muller, J.Y.3
Welch, C.L.4
Gu, W.5
Accili, D.6
-
133
-
-
67650254143
-
Therapeutic angiogenesis in diabetes and hypercholesterolemia: Influence of oxidative stress
-
Boodhwani M, Sellke FW. Therapeutic angiogenesis in diabetes and hypercholesterolemia: Influence of oxidative stress. Antiox Redox Signal. 2009;11:1945-1959.
-
(2009)
Antiox Redox Signal
, vol.11
, pp. 1945-1959
-
-
Boodhwani, M.1
Sellke, F.W.2
-
134
-
-
77952097700
-
Endothelial progenitor cells in vascular health: Focus on lifestyle
-
Van Craenenbroeck EM, Conraads VM. Endothelial progenitor cells in vascular health: Focus on lifestyle. Microvasc Res. 2010;79:184-192.
-
(2010)
Microvasc Res
, vol.79
, pp. 184-192
-
-
Van Craenenbroeck, E.M.1
Conraads, V.M.2
-
137
-
-
0030739144
-
Estrogen acutely stimulates nitric oxide synthase activity in fetal pulmonary artery endothelium
-
Lantin-Hermoso RL, Rosenfeld CR, Yuhanna IS, German Z, Chen Z, Shaul P. Estrogen acutely stimulates nitric oxide synthase activity in fetal pulmonary artery endothelium. Am J Physiol. 1997;273: L119-L126.
-
(1997)
Am J Physiol
, vol.273
-
-
Lantin-Hermoso, R.L.1
Rosenfeld, C.R.2
Yuhanna, I.S.3
German, Z.4
Chen, Z.5
Shaul, P.6
-
138
-
-
0036488359
-
Effect of estrogen on endothelial function and angiogenesis
-
Rubanyi GM, Johns A, Kauser K. Effect of estrogen on endothelial function and angiogenesis. Vascul Pharmacol. 2002;38:89-98.
-
(2002)
Vascul Pharmacol
, vol.38
, pp. 89-98
-
-
Rubanyi, G.M.1
Johns, A.2
Kauser, K.3
-
139
-
-
48049098413
-
Estrogen receptor-alpha and endothelial nitric oxide synthase nuclear complex regulates transcription of human telomerase
-
Grasselli A, Nanni S, Colussi C, Aiello A, Benvenuti V, Ragone G, Moretti F, Sacchi A, Bacchetti S, Gaetano C, Capogrossi M, Pontecorvi A, Farsetti A. Estrogen receptor-alpha and endothelial nitric oxide synthase nuclear complex regulates transcription of human telomerase. Circ Res. 2008;103:34-42.
-
(2008)
Circ Res
, vol.103
, pp. 34-42
-
-
Grasselli, A.1
Nanni, S.2
Colussi, C.3
Aiello, A.4
Benvenuti, V.5
Ragone, G.6
Moretti, F.7
Sacchi, A.8
Bacchetti, S.9
Gaetano, C.10
Capogrossi, M.11
Pontecorvi, A.12
Farsetti, A.13
-
140
-
-
24144438187
-
Estrogen reduces endothelial progenitor cell senescence through augmentation of telomerase activity
-
Imanishi T, Hano T, Nishio I. Estrogen reduces endothelial progenitor cell senescence through augmentation of telomerase activity. J Hypertens. 2005;23:1699-1706.
-
(2005)
J Hypertens
, vol.23
, pp. 1699-1706
-
-
Imanishi, T.1
Hano, T.2
Nishio, I.3
-
141
-
-
0346157997
-
Estrogen-mediated, endothelial nitric oxide synthase-dependent mobilization of bone marrow-derived endothelial progenitor cells contributes to reendothelialization after arterial injury
-
Iwakura A, Luedemann C, Shastry S, Hanley A, Kearney M, Aikawa R, Isner J, Asahara T, Losordo D. Estrogen-mediated, endothelial nitric oxide synthase-dependent mobilization of bone marrow-derived endothelial progenitor cells contributes to reendothelialization after arterial injury. Circulation. 2003;108:3115-3121.
-
(2003)
Circulation
, vol.108
, pp. 3115-3121
-
-
Iwakura, A.1
Luedemann, C.2
Shastry, S.3
Hanley, A.4
Kearney, M.5
Aikawa, R.6
Isner, J.7
Asahara, T.8
Losordo, D.9
-
142
-
-
20444441960
-
Estrogen reduces angiotensin II-induced acceleration of senescence in endothelial progenitor cells
-
Imanishi T, Hano T, Nishio I. Estrogen reduces angiotensin II-induced acceleration of senescence in endothelial progenitor cells. Hypertens Res. 2005;28:263-271.
-
(2005)
Hypertens Res
, vol.28
, pp. 263-271
-
-
Imanishi, T.1
Hano, T.2
Nishio, I.3
-
143
-
-
58649114730
-
The telomerase tale in vascular aging: Regulation by estrogens and nitric oxide signaling
-
Farsetti A, Grasselli A, Bacchetti S, Gaetano C, Capogrossi M. The telomerase tale in vascular aging: Regulation by estrogens and nitric oxide signaling. J Appl Physiol. 2009;106:333-337.
-
(2009)
J Appl Physiol
, vol.106
, pp. 333-337
-
-
Farsetti, A.1
Grasselli, A.2
Bacchetti, S.3
Gaetano, C.4
Capogrossi, M.5
-
145
-
-
0037125379
-
Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative randomized controlled trial
-
Rossouw JE, Anderson GL, Prentice RL, LaCroix A, Kooperberg C, Stefanick M, Jackson R, Beresford S, Howard B, Johnson K, Kotchen J, Ockene J. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative randomized controlled trial. JAMA. 2002;288:321-333.
-
(2002)
JAMA
, vol.288
, pp. 321-333
-
-
Rossouw, J.E.1
Anderson, G.L.2
Prentice, R.L.3
Lacroix, A.4
Kooperberg, C.5
Stefanick, M.6
Jackson, R.7
Beresford, S.8
Howard, B.9
Johnson, K.10
Kotchen, J.11
Ockene, J.12
-
146
-
-
68949152715
-
Postmenopausal hormone therapy and the risk of cardiovascular disease
-
Bittner V. Postmenopausal hormone therapy and the risk of cardiovascular disease. Expert Opin Pharmacother. 2009;10:2041-2053.
-
(2009)
Expert Opin Pharmacother
, vol.10
, pp. 2041-2053
-
-
Bittner, V.1
-
147
-
-
80051978810
-
Therapeutic effect of enhancing endothelial nitric oxide synthase (enos) expression and preventing enos uncoupling
-
Forstermann U, Li H. Therapeutic effect of enhancing endothelial nitric oxide synthase (enos) expression and preventing enos uncoupling. Br J Pharmacol. 2011;164:213-223.
-
(2011)
Br J Pharmacol
, vol.164
, pp. 213-223
-
-
Forstermann, U.1
Li, H.2
-
148
-
-
0032879970
-
Gene transfer of endothelial nitric oxide synthase (eNOS) in eNOSdeficient mice
-
Lake-Bruse KD, Faraci FM, Shesely EG, Maeda N, Sigmund C, Heistad D. Gene transfer of endothelial nitric oxide synthase (eNOS) in eNOSdeficient mice. Am J Physiol. 1999;277:H770-H776.
-
(1999)
Am J Physiol
, vol.277
-
-
Lake-Bruse, K.D.1
Faraci, F.M.2
Shesely, E.G.3
Maeda, N.4
Sigmund, C.5
Heistad, D.6
-
149
-
-
0242361643
-
Angiogenesis induced by endothelial nitric oxide synthase gene through vascular endothelial growth factor expression in a rat hindlimb ischemia model
-
Namba T, Koike H, Murakami K, Aoki M, Makino H, Hashiya N, Ogihara T, Kaneda Y, Kohno M, Morishita R. Angiogenesis induced by endothelial nitric oxide synthase gene through vascular endothelial growth factor expression in a rat hindlimb ischemia model. Circulation. 2003;108:2250-2257.
-
(2003)
Circulation
, vol.108
, pp. 2250-2257
-
-
Namba, T.1
Koike, H.2
Murakami, K.3
Aoki, M.4
Makino, H.5
Hashiya, N.6
Ogihara, T.7
Kaneda, Y.8
Kohno, M.9
Morishita, R.10
-
150
-
-
79961031512
-
Rapid, direct effects of statin treatment on arterial redox state and nitric oxide bioavailability in human atherosclerosis via tetrahydrobiopterin- mediated endothelial nitric oxide synthase coupling
-
Antoniades C, Bakogiannis C, Leeson P, et al. Rapid, direct effects of statin treatment on arterial redox state and nitric oxide bioavailability in human atherosclerosis via tetrahydrobiopterin-mediated endothelial nitric oxide synthase coupling. Circulation. 2011;124:335-345.
-
(2011)
Circulation
, vol.124
, pp. 335-345
-
-
Antoniades, C.1
Bakogiannis, C.2
Leeson, P.3
-
151
-
-
0033826581
-
The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals
-
Kureishi Y, Luo Z, Shiojima I, Bialik A, Fulton D, Lefer DJ, Sessa WC, Walsh K. The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals. Nat Med. 2000;6:1004-1010.
-
(2000)
Nat Med
, vol.6
, pp. 1004-1010
-
-
Kureishi, Y.1
Luo, Z.2
Shiojima, I.3
Bialik, A.4
Fulton, D.5
Lefer, D.J.6
Sessa, W.C.7
Walsh, K.8
-
152
-
-
0034619383
-
Hypercholesterolemia inhibits angiogenesis in response to hindlimb ischemia: Nitric oxide-dependent mechanism
-
Duan J, Murohara T, Ikeda H, Katoh A, Shintani S, Sasaki K, Kawata H, Yamamoto N, Imaizumi T. Hypercholesterolemia inhibits angiogenesis in response to hindlimb ischemia: Nitric oxide-dependent mechanism. Circulation. 2000;102:III370-III376.
-
(2000)
Circulation
, vol.102
-
-
Duan, J.1
Murohara, T.2
Ikeda, H.3
Katoh, A.4
Shintani, S.5
Sasaki, K.6
Kawata, H.7
Yamamoto, N.8
Imaizumi, T.9
-
153
-
-
79955960774
-
Nitrite supplementation reverses vascular endothelial dysfunction and large elastic artery stiffness with aging
-
Sindler AL, Fleenor BS, Calvert JW, Marshall K, Zigler M, Lefer D, Seals D. Nitrite supplementation reverses vascular endothelial dysfunction and large elastic artery stiffness with aging. Aging Cell. 2011; 10:429-437.
-
(2011)
Aging Cell
, vol.10
, pp. 429-437
-
-
Sindler, A.L.1
Fleenor, B.S.2
Calvert, J.W.3
Marshall, K.4
Zigler, M.5
Lefer, D.6
Seals, D.7
-
154
-
-
1242275127
-
Prevention and reversal of premature endothelial cell senescence and vasculopathy in obesity-induced diabetes by ebselen
-
Brodsky SV, Gealekman O, Chen J, Zhang F, Togashi N, Crabtree M, Gross S, Nasjletti A, Goligorsky M. Prevention and reversal of premature endothelial cell senescence and vasculopathy in obesity-induced diabetes by ebselen. Circ Res. 2004;94:377-384.
-
(2004)
Circ Res
, vol.94
, pp. 377-384
-
-
Brodsky, S.V.1
Gealekman, O.2
Chen, J.3
Zhang, F.4
Togashi, N.5
Crabtree, M.6
Gross, S.7
Nasjletti, A.8
Goligorsky, M.9
-
155
-
-
79958792472
-
Exercise protects against myocardial ischemia-reperfusion injury via stimulation of beta(3)-adrenergic receptors and increased nitric oxide signaling: Role of nitrite and nitrosothiols
-
Calvert JW, Condit ME, Aragon JP, Nicholson C, Moody B, Hood R, Sindler A, Gundewar S, Seals D, Barouch L, Lefer D. Exercise protects against myocardial ischemia-reperfusion injury via stimulation of beta(3)-adrenergic receptors and increased nitric oxide signaling: Role of nitrite and nitrosothiols. Circ Res. 2011;108:1448-1458.
-
(2011)
Circ Res
, vol.108
, pp. 1448-1458
-
-
Calvert, J.W.1
Condit, M.E.2
Aragon, J.P.3
Nicholson, C.4
Moody, B.5
Hood, R.6
Sindler, A.7
Gundewar, S.8
Seals, D.9
Barouch, L.10
Lefer, D.11
-
156
-
-
33645838355
-
An engineered vegf-activating zinc finger protein transcription factor improves blood flow and limb salvage in advanced-age mice
-
Yu J. An engineered vegf-activating zinc finger protein transcription factor improves blood flow and limb salvage in advanced-age mice. FASEB J. 2006;20:479-481.
-
(2006)
FASEB J
, vol.20
, pp. 479-481
-
-
Yu, J.1
-
157
-
-
0034960583
-
The morphogen Sonic hedgehog is an indirect angiogenic agent upregulating two families of angiogenic growth factors
-
Pola R, Ling LE, Silver M, Corbley M, Kearney M, Blake Pepinsky R, Shapiro R, Taylor F, Baker D, Asahara T, Isner J. The morphogen Sonic hedgehog is an indirect angiogenic agent upregulating two families of angiogenic growth factors. Nat Med. 2001;7:706-711.
-
(2001)
Nat Med
, vol.7
, pp. 706-711
-
-
Pola, R.1
Ling, L.E.2
Silver, M.3
Corbley, M.4
Kearney, M.5
Blake Pepinsky, R.6
Shapiro, R.7
Taylor, F.8
Baker, D.9
Asahara, T.10
Isner, J.11
-
158
-
-
20244373955
-
Telomerase mediates vascular endothelial growth factor-dependent responsiveness in a rat model of hind limb ischemia
-
Zaccagnini G, Gaetano C, Della Pietra L, et al. Telomerase mediates vascular endothelial growth factor-dependent responsiveness in a rat model of hind limb ischemia. J Biol Chem. 2005;280:14790-14798.
-
(2005)
J Biol Chem
, vol.280
, pp. 14790-14798
-
-
Zaccagnini, G.1
Gaetano, C.2
Della Pietra, L.3
-
159
-
-
77951229383
-
VEGFDdeltaNdeltaC mediated angiogenesis in skeletal muscles of diabetic WHHL rabbits
-
Roy H, Bhardwaj S, Babu M, Lahteenvuo J, Yla-Herttuala S. VEGFDdeltaNdeltaC mediated angiogenesis in skeletal muscles of diabetic WHHL rabbits. Eur J Clin Invest. 2010;40:422-432.
-
(2010)
Eur J Clin Invest
, vol.40
, pp. 422-432
-
-
Roy, H.1
Bhardwaj, S.2
Babu, M.3
Lahteenvuo, J.4
Yla-Herttuala, S.5
-
160
-
-
20144386684
-
Direct intramyocardial plasmid vascular endothelial growth factor-A165 gene therapy in patients with stable severe angina pectoris a randomized double-blind placebo-controlled study: The Euroinject One trial
-
Kastrup J, Jorgensen E, Ruck A, Tagil K, Glogar D, Ruzyllo W, Botker H, Dudek D, Drvota V, Hesse B, Thuesen L, Blomberg P, Gyongyosi M, Sylven C. Direct intramyocardial plasmid vascular endothelial growth factor-A165 gene therapy in patients with stable severe angina pectoris a randomized double-blind placebo-controlled study: The Euroinject One trial. J Am Coll Cardiol. 2005;45:982-988.
-
(2005)
J Am Coll Cardiol
, vol.45
, pp. 982-988
-
-
Kastrup, J.1
Jorgensen, E.2
Ruck, A.3
Tagil, K.4
Glogar, D.5
Ruzyllo, W.6
Botker, H.7
Dudek, D.8
Drvota, V.9
Hesse, B.10
Thuesen, L.11
Blomberg, P.12
Gyongyosi, M.13
Sylven, C.14
-
161
-
-
0037133624
-
Angiogenic gene therapy (AGENT) trial in patients with stable angina pectoris
-
Grines CL, Watkins MW, Helmer G, Penny W, Brinker J, Marmur J, West A, Rade J, Marrott P, Hammond H, Engler R. Angiogenic gene therapy (AGENT) trial in patients with stable angina pectoris. Circulation. 2002;105:1291-1297.
-
(2002)
Circulation
, vol.105
, pp. 1291-1297
-
-
Grines, C.L.1
Watkins, M.W.2
Helmer, G.3
Penny, W.4
Brinker, J.5
Marmur, J.6
West, A.7
Rade, J.8
Marrott, P.9
Hammond, H.10
Engler, R.11
-
162
-
-
0037453099
-
The VIVA trial: Vascular endothelial growth factor in Ischemia for Vascular Angiogenesis
-
Henry TD, Annex BH, McKendall GR, et al. The VIVA trial: Vascular endothelial growth factor in Ischemia for Vascular Angiogenesis. Circulation. 2003;107:1359-1365.
-
(2003)
Circulation
, vol.107
, pp. 1359-1365
-
-
Henry, T.D.1
Annex, B.H.2
McKendall, G.R.3
-
163
-
-
18844417604
-
Gene therapy for ischemic cardiovascular diseases: Some lessons learned from the first clinical trials
-
Yla-Herttuala S, Markkanen JE, Rissanen TT. Gene therapy for ischemic cardiovascular diseases: Some lessons learned from the first clinical trials. Trends Cardiovasc Med. 2004;14:295-300.
-
(2004)
Trends Cardiovasc Med
, vol.14
, pp. 295-300
-
-
Yla-Herttuala, S.1
Markkanen, J.E.2
Rissanen, T.T.3
-
164
-
-
78049441699
-
Lifestyle impacts on the aging-associated expression of biomarkers of DNA damage and telomere dysfunction in human blood
-
Song Z, von Figura G, Liu Y, Kraus J, Torrice C, Dillon P, Rudolph-Watabe M, Ju Z, Kestler H, Sanoff H, Lenhard Rudolph K. Lifestyle impacts on the aging-associated expression of biomarkers of DNA damage and telomere dysfunction in human blood. Aging Cell. 2010;9: 607-615.
-
(2010)
Aging Cell
, vol.9
, pp. 607-615
-
-
Song, Z.1
Von Figura, G.2
Liu, Y.3
Kraus, J.4
Torrice, C.5
Dillon, P.6
Rudolph-Watabe, M.7
Ju, Z.8
Kestler, H.9
Sanoff, H.10
Lenhard Rudolph, K.11
-
165
-
-
77955845440
-
The power of exercise: Buffering the effect of chronic stress on telomere length
-
Puterman E, Lin J, Blackburn E, O'Donovan A, Adler N, Epel E. The power of exercise: Buffering the effect of chronic stress on telomere length. PLoS One. 2010;5:e10837.
-
(2010)
PLoS One
, vol.5
-
-
Puterman, E.1
Lin, J.2
Blackburn, E.3
O'Donovan, A.4
Adler, N.5
Epel, E.6
-
166
-
-
58149302774
-
Relationship between physical activity level, telomere length, and telomerase activity
-
Ludlow AT, Zimmerman JB, Witkowski S, Hearn J, Hatfield B, Roth S. Relationship between physical activity level, telomere length, and telomerase activity. Med Sci Sports Exerc. 2008;40:1764-1771.
-
(2008)
Med Sci Sports Exerc
, vol.40
, pp. 1764-1771
-
-
Ludlow, A.T.1
Zimmerman, J.B.2
Witkowski, S.3
Hearn, J.4
Hatfield, B.5
Roth, S.6
-
167
-
-
84860138648
-
Effect of exercise training on vascular endothelial function in patients with stable coronary artery disease: A randomized controlled trial
-
Jul [Epub ahead of print]
-
Luk T, Dai Y, Siu C, Yiu K, Chan H, Lee S, Li S, Fong B, Wong W, Tam S, Lau C, Tse H. Effect of exercise training on vascular endothelial function in patients with stable coronary artery disease: A randomized controlled trial. Eur J Cardiovasc Prev Rehabil. 2011 Jul [Epub ahead of print].
-
(2011)
Eur J Cardiovasc Prev Rehabil
-
-
Luk, T.1
Dai, Y.2
Siu, C.3
Yiu, K.4
Chan, H.5
Lee, S.6
Li, S.7
Fong, B.8
Wong, W.9
Tam, S.10
Lau, C.11
Tse, H.12
-
168
-
-
79960223602
-
Exercise training increases endothelial progenitor cells and decreases asymmetric dimethylarginine in peripheral arterial disease: A randomized controlled trial
-
Schlager O, Giurgea A, Schuhfried O, Seidinger D, Hammer A, Groger M,
-
(2011)
Atherosclerosis
, vol.217
, pp. 240-248
-
-
Schlager, O.1
Giurgea, A.2
Schuhfried, O.3
Seidinger, D.4
Hammer, A.5
Groger, M.6
Fialka-Moser, V.7
Gschwandtner, M.8
Koppensteiner, R.9
Steiner, S.10
-
169
-
-
77956183960
-
Exercise training improves function of circulating angiogenic cells in patients with chronic heart failure
-
Van Craenenbroeck EM, Hoymans VY, Beckers PJ, Possemiers N, Wuyts K, Paelinck B, Vrints C, Conraads V. Exercise training improves function of circulating angiogenic cells in patients with chronic heart failure. Basic Res Cardiol. 2010;105:665-676.
-
(2010)
Basic Res Cardiol
, vol.105
, pp. 665-676
-
-
Van Craenenbroeck, E.M.1
Hoymans, V.Y.2
Beckers, P.J.3
Possemiers, N.4
Wuyts, K.5
Paelinck, B.6
Vrints, C.7
Conraads, V.8
|