Mechanisms of endothelial senescence

Experimental Physiology

Volumn 94, Issue 3, 2009, Pages 299-304

  Erusalimsky, Jorge D ^a   Skene, Chris ^b  

^a CARDIFF METROPOLITAN UNIVERSITY   (United Kingdom)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

DNA; TELOMERASE;

CELL CULTURE; CELL DIVISION; CONFERENCE PAPER; ENDOTHELIUM CELL; OXIDATIVE STRESS; TELOMERE;

EID: 60349113539     PISSN: 09580670     EISSN: 1469445X     Source Type: Journal    
DOI: 10.1113/expphysiol.2008.043133     Document Type: Conference Paper

References (41)

1. Aviv H, Khan MY, Skurnick J, Okuda K, Kimura M, Gardner J, Priolo L & Aviv A (2001). Age dependent aneuploidy and telomere length of the human vascular endothelium. Atherosclerosis 159, 281 287.
2. Borras C, Esteve JM, Vina JR, Sastre J, Vina J & Pallardo FV (2004). Glutathione regulates telomerase activity in 3T3 fibroblasts. J Biol Chem 279, 34332 34335.
3. Burrig KF (1991). The endothelium of advanced arteriosclerotic plaques in humans. Arterioscler Thromb 11, 1678 1689.
4. Campisi J (1996). Replicative senescence: an old lives' tale? Cell 84, 497 500.
5. Caplan BA & Schwartz CJ (1973). Increased endothelial cell turnover in areas of in vivo Evans Blue uptake in the pig aorta. Atherosclerosis 17, 401 417.
6. Chang E & Harley CB (1995). Telomere length and replicative aging in human vascular tissues. Proc Natl Acad Sci USA 92, 11190 11194.
7. Chen J, Brodsky SV, Goligorsky DM, Hampel DJ, Li H, Gross SS & Goligorsky MS (2002). Glycated collagen I induces premature senescence-like phenotypic changes in endothelial cells. Circ Res 90, 1290 1298.
8. Chen QM, Prowse KR, Tu VC, Purdom S & Linskens MH (2001). Uncoupling the senescent phenotype from telomere shortening in hydrogen peroxide-treated fibroblasts. Exp Cell Res 265, 294 303.
9. Clementi E, Brown GC, Feelisch M & Moncada, S (1998). Persistent inhibition of cell respiration by nitric oxide: crucial role of S-nitrosylation of mitochondrial complex I and protective action of glutathione. Proc Natl Acad Sci U S A 95, 7631 7636.
10. D'Adda Di Fagagna F, Reaper PM, Clay-Farrace L, Fiegler H, Carr P, Von Zglinicki T, Saretzki G, Carter NP & Jackson SP (2003). A DNA damage checkpoint response in telomere-initiated senescence. Nature 426, 194 198.
11. Dimri GP, Lee X, Basile G, Acosta M, Scott G, Roskelley C, Medrano EE, Linskens M, Rubelj I & Pereira-Smith O (1995). A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci USA 92, 9363 9367.
12. Erusalimsky JD & Moncada S (2007). Nitric oxide and mitochondrial signaling: from physiology to pathophysiology. Arterioscler Thromb Vasc Biol 27, 2524 2531.
13. Fenton M, Barker S, Kurz DJ & Erusalimsky JD (2001). Cellular senescence after single and repeated balloon catheter denudations of rabbit carotid arteries. Arterioscler Thromb Vasc Biol 21, 220 226.
14. Furumoto K, Inoue E, Nagao N, Hiyama E & Miwa N (1998). Age-dependent telomere shortening is slowed down by enrichment of intracellular vitamin C via suppression of oxidative stress. Life Sci 63, 935 948.
15. Greider CW (1998). Telomeres and senescence: the history, the experiment, the future. Current Biol 8, R178 R181.
16. Hayflick L (1965). The limited in vitro life time of human diploid cell strains. Exp Cell Res 37, 614 636.
17. Hayflick L & Moorhead PS (1961). The serial cultivation of human diploid cell strains. Exp Cell Res 25, 586 621.
18. Hong Y, Quintero M, Frakich NM, Trivier E & Erusalimsky JD (2007). Evidence against the involvement of nitric oxide in the modulation of telomerase activity or replicative capacity of human endothelial cells. Exp Gerontol 42, 904 910.
19. Hsiao R, Sharma HW, Ramakrishnan S, Keith E & Narayanan R (1997). Telomerase activity in normal human endothelial cells. Anticancer Res 17, 827 832.
20. Kurz DJ, Decary S, Hong Y & Erusalimsky JD (2000). Senescence-associated β-galactosidase reflects an increase in lysosomal mass during replicative ageing of human endothelial cells. J Cell Sci 113, 3613 3622.
21. Kurz DJ, Decary S, Hong Y, Trivier E, Akhmedov A & Erusalimsky JD (2004). Chronic oxidative stress compromises telomere integrity and accelerates the onset of senescence in human endothelial cells. J Cell Sci 117, 2417 2426.
22. Kurz DJ, Hong Y, Trivier E, Huang HL, Decary S, Zang GH, Luscher TF & Erusalimsky JD (2003). Fibroblast growth factor-2, but not vascular endothelial growth factor, upregulates telomerase activity in human endothelial cells. Arterioscler Thromb Vasc Biol 23, 748 754.
23. Madamanchi NR, Vendrov A & Runge MS (2005). Oxidative stress and vascular disease. Arterioscler Thromb Vasc Biol 25, 29 38.
24. Masutomi K, Yu EY, Khurts S, Ben-Porath I, Currier JL, Metz GB, Brooks MW, Kaneko S, Murakami S, DeCaprio JA, Weinberg RA, Stewart SA & Hahn WC (2003). Telomerase maintains telomere structure in normal human cells. Cell 114, 241 253.
25. Minamino T, Miyauchi H, Yoshida T, Ishida Y, Yoshida H & Komuro I (2002). Endothelial cell senescence in human atherosclerosis: role of telomere in endothelial dysfunction. Circulation 105, 1541 1544.
26. Ogami M, Ikura Y, Ohsawa M, Matsuo T, Kayo S, Yoshimi N, Hai E, Shirai N, Ehara S, Komatsu R, Naruko T & Ueda M (2004). Telomere shortening in human coronary artery diseases. Arterioscler Thromb Vasc Biol 24, 546 550.
27. Okuda K, Khan MY, Skurnick J, Kimura M, Aviv H & Aviv A (2000). Telomere attrition of the human abdominal aorta: relationships with age and atherosclerosis. Atherosclerosis 152, 391 398.
28. Repin VS, Dolgov VV, Zaikina OE, Novikov ID, Antonov AS, Nikolaeva MA & Smirnov VN (1984). Heterogeneity of endothelium in human aorta. A quantitative analysis by scanning electron microscopy. Atherosclerosis 50, 35 52.
29. Schwartz SM, Gajdusek CM, Reidy MA, Selden SC III. & Haudenschild CC (1980). Maintenance of integrity in aortic endothelium. Fed Proc 39, 2618 2625.
30. Toussaint O, Medrano EE & Von Zglinicki T (2000). Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytes. Exp Gerontol 35, 927 945.
31. Trivier E, Kurz DJ, Hong Y, Huang HL & Erusalimsky JD (2004). Differential regulation of telomerase in endothelial cells by fibroblast growth factor-2 and vascular endothelial growth factor-A: association with replicative life span. Ann N Y Acad Sci 1019, 111 115.
32. Van Der Loo B, Fenton MJ & Erusalimsky JD (1998). Cytochemical detection of a senescence-associated β-galactosidase in endothelial and smooth muscle cells from human and rabbit blood vessels. Exp Cell Res 241, 309 315.
33. Vasa M, Breitschopf K, Zeiher AM & Dimmeler S (2000). Nitric oxide activates telomerase and delays endothelial cell senescence. Circ Res 87, 540 542.
34. Vasile E, Tomita Y, Brown LF, Kocher O & Dvorak HF (2001). Differential expression of thymosin β-10 by early passage and senescent vascular endothelium is modulated by VPF/VEGF: evidence for senescent endothelial cells in vivo at sites of atherosclerosis. FASEB J 15, 458 466.
35. Von Zglinicki T (2002). Oxidative stress shortens telomeres. Trends Biochem Sci 27, 339 344.
36. Von Zglinicki T, Saretzki G, Ladhoff J, D'Adda DF & Jackson SP (2005). Human cell senescence as a DNA damage response. Mech Ageing Dev 126, 111 117.
37. Wright HP (1968). Endothelial mitosis around aortic branches in normal guinea pigs. Nature 220, 78 79.
38. Xu D, Neville R & Finkel T (2000). Homocysteine accelerates endothelial cell senescence. FEBS Lett 470, 20 24.
39. Yang J, Chang E, Cherry AM, Bangs CD, Oei Y, Bodnar A, Bronstein A, Chiu CP & Herron GS (1999). Human endothelial cell life extension by telomerase expression. J Biol Chem 274, 26141 26148.
40. Yaswen P & Campisi J (2007). Oncogene-induced senescence pathways weave an intricate tapestry. Cell 128, 233 234.
41. Zaccagnini G, Gaetano C, La Pietra L, Nanni S, Grasselli A, Mangoni A, Benvenuto R, Fabrizi M, Truffa S, Germani A, Moretti F, Pontecorvi A, Sacchi A, Bacchetti S, Capogrossi MC & Farsetti A (2005). Telomerase mediates vascular endothelial growth factor-dependent responsiveness in a rat model of hind limb ischemia. J Biol Chem 280, 14790 14798.