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Volumn 134, Issue 3, 1996, Pages 783-791

FGF-1-dependent proliferative and migratory responses are impaired in senescent human umbilical vein endothelial cells and correlate with the inability to signal tyrosine phosphorylation of fibroblast growth factor receptor-1 substrates

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR 1;

EID: 0029758451     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.134.3.783     Document Type: Article
Times cited : (74)

References (53)
  • 1
    • 0027385553 scopus 로고
    • Senescence of aortic endothelial cells in culture: Effects of basic fibroblast growth factor expression on cell phenotype, migration, and proliferation
    • Augustin-Voss, H.G., A.K. Voss, and B.U. Pauli. 1993. Senescence of aortic endothelial cells in culture: Effects of basic fibroblast growth factor expression on cell phenotype, migration, and proliferation. J. Cell. Physiol. 157:279-288.
    • (1993) J. Cell. Physiol. , vol.157 , pp. 279-288
    • Augustin-Voss, H.G.1    Voss, A.K.2    Pauli, B.U.3
  • 2
    • 0025175587 scopus 로고
    • Possible dissociation of the heparin-binding and mitogenic activities of heparin-binding (acidic fibroblast) growth factor-1 from its receptor-binding activities by site-directed mutagenesis of a single lysine residue
    • Burgess, W.H., A.M. Shaheen, M. Ravera, M. Jaye, P.J. Donohue, and J.A. Winkles. 1990. Possible dissociation of the heparin-binding and mitogenic activities of heparin-binding (acidic fibroblast) growth factor-1 from its receptor-binding activities by site-directed mutagenesis of a single lysine residue. J. Cell Biol. 111:2129-2138.
    • (1990) J. Cell Biol. , vol.111 , pp. 2129-2138
    • Burgess, W.H.1    Shaheen, A.M.2    Ravera, M.3    Jaye, M.4    Donohue, P.J.5    Winkles, J.A.6
  • 3
    • 0024150623 scopus 로고
    • Focal adhesions: Transmembrane junctions between the extracellular matrix and cytoskeleton
    • Burridge, K., K. Fath, T. Kelly, G. Nuckolls, and C. Turner. 1988. Focal adhesions: Transmembrane junctions between the extracellular matrix and cytoskeleton. Annu. Rev. Cell Biol. 4:487-525.
    • (1988) Annu. Rev. Cell Biol. , vol.4 , pp. 487-525
    • Burridge, K.1    Fath, K.2    Kelly, T.3    Nuckolls, G.4    Turner, C.5
  • 4
    • 0021071034 scopus 로고
    • Diminished in vitro kinase activity of the EGF receptor of senescent human fibroblasts
    • Carlin, C., P.D. Phillips, B.B. Knowles, and V.J. Cristofalo. 1983. Diminished in vitro kinase activity of the EGF receptor of senescent human fibroblasts. Nature (Lond.). 306:617-620.
    • (1983) Nature (Lond.) , vol.306 , pp. 617-620
    • Carlin, C.1    Phillips, P.D.2    Knowles, B.B.3    Cristofalo, V.J.4
  • 5
    • 0027300619 scopus 로고
    • The when and how of src regulation
    • Cooper, J.A., and B. Howell. 1993. The when and how of src regulation. Cell. 73:1051-1054.
    • (1993) Cell , vol.73 , pp. 1051-1054
    • Cooper, J.A.1    Howell, B.2
  • 8
    • 0027279294 scopus 로고
    • Controlled induction of focal adhesion disassembly and migration in primary fibroblasts
    • Dunlevy, J.R., and J.R. Couchman. 1993. Controlled induction of focal adhesion disassembly and migration in primary fibroblasts. J. Cell Sci. 105: 489-500.
    • (1993) J. Cell Sci. , vol.105 , pp. 489-500
    • Dunlevy, J.R.1    Couchman, J.R.2
  • 9
    • 0025021471 scopus 로고
    • Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist
    • Eisenberg, S.P., R.J. Evans, W.P. Arend, E. Verderber, M.T. Brewer, C.H. Hannum, and R.C. Thompson. 1990. Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist. Nature (Lond.). 343:341-346.
    • (1990) Nature (Lond.) , vol.343 , pp. 341-346
    • Eisenberg, S.P.1    Evans, R.J.2    Arend, W.P.3    Verderber, E.4    Brewer, M.T.5    Hannum, C.H.6    Thompson, R.C.7
  • 12
    • 0029143960 scopus 로고
    • Molecular mechanisms of angiogenesis: Fibroblast growth factor signal transduction
    • Friesel, R.E., and T. Maciag. 1995. Molecular mechanisms of angiogenesis: Fibroblast growth factor signal transduction. FASEB J. 9:919-925.
    • (1995) FASEB J. , vol.9 , pp. 919-925
    • Friesel, R.E.1    Maciag, T.2
  • 13
    • 0023118633 scopus 로고
    • Inhibition of endothelial cell proliferation by gamma interferon
    • Friesel, R., A. Komoriya, and T. Maciag. 1987. Inhibition of endothelial cell proliferation by gamma interferon. J. Cell Biol. 104:689-696.
    • (1987) J. Cell Biol. , vol.104 , pp. 689-696
    • Friesel, R.1    Komoriya, A.2    Maciag, T.3
  • 14
    • 0026464913 scopus 로고
    • Interleukin-1α mediates an alternative pathway for the antiproliferative action of poly(I.C) on human endothelial cells
    • Garfinkel, S., D.S. Haines, S. Brown, J. Wessendorf, D.H. Gillespie, and T. Maciag. 1992. Interleukin-1α mediates an alternative pathway for the antiproliferative action of poly(I.C) on human endothelial cells. J. Biol. Chem. 267:24375-24378.
    • (1992) J. Biol. Chem. , vol.267 , pp. 24375-24378
    • Garfinkel, S.1    Haines, D.S.2    Brown, S.3    Wessendorf, J.4    Gillespie, D.H.5    Maciag, T.6
  • 15
    • 0028014602 scopus 로고
    • Post-transcriptional regulation of IL-1α in various strains of young and senescent human umbilical vein endothelial cells
    • Garfinkel, S., S. Brown, J.H.M. Wessendorf, and T. Maciag. 1994. Post-transcriptional regulation of IL-1α in various strains of young and senescent human umbilical vein endothelial cells. Proc. Natl. Acad. Sci. USA. 91:1559-1563.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 1559-1563
    • Garfinkel, S.1    Brown, S.2    Wessendorf, J.H.M.3    Maciag, T.4
  • 16
    • 0025248130 scopus 로고
    • Heparin-binding growth factor-1 stimulation of human endothelial cells induces platelet-derived growth factor A-chain gene expression
    • Gay, C.G., and J.A. Winkles. 1990. Heparin-binding growth factor-1 stimulation of human endothelial cells induces platelet-derived growth factor A-chain gene expression. J. Biol. Chem. 265:3284-3292.
    • (1990) J. Biol. Chem. , vol.265 , pp. 3284-3292
    • Gay, C.G.1    Winkles, J.A.2
  • 17
    • 50549218525 scopus 로고
    • The limited in vitro lifespan of human diploid cell strains
    • Hayflick, L. 1965. The limited in vitro lifespan of human diploid cell strains. Exp. Cell Res. 37:614-636.
    • (1965) Exp. Cell Res. , vol.37 , pp. 614-636
    • Hayflick, L.1
  • 18
    • 0028059879 scopus 로고
    • Csk suppression of Src involves movement of Csk to sites of Src activity
    • Howell, B.W., and J.A. Cooper. 1994. Csk suppression of Src involves movement of Csk to sites of Src activity. Mol. Cell. Biol. 14:5402-5411.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 5402-5411
    • Howell, B.W.1    Cooper, J.A.2
  • 21
    • 0026611047 scopus 로고
    • Association of p60(c-src) with endosomal membranes in mammalian fibroblasts
    • Kaplan, K.B., J.R. Swedlow, H.E. Varmus, and D.O. Morgan. 1992. Association of p60(c-src) with endosomal membranes in mammalian fibroblasts. J. Cell Biol. 118:321-333.
    • (1992) J. Cell Biol. , vol.118 , pp. 321-333
    • Kaplan, K.B.1    Swedlow, J.R.2    Varmus, H.E.3    Morgan, D.O.4
  • 22
    • 0028151515 scopus 로고
    • Association of the amino-terminal half of c-src with focal adhesions alters their properties and is regulated by phosphorylation of tyrosine 527
    • Kaplan, K.B., K.B. Bibbins, J.R. Swedlow, M. Arnaud, D.O. Morgan, and H.E. Varmus. 1994. Association of the amino-terminal half of c-src with focal adhesions alters their properties and is regulated by phosphorylation of tyrosine 527. EMBO (Eur. Mol. Biol. Organ.) J. 13:4745-4756.
    • (1994) EMBO (Eur. Mol. Biol. Organ.) J. , vol.13 , pp. 4745-4756
    • Kaplan, K.B.1    Bibbins, K.B.2    Swedlow, J.R.3    Arnaud, M.4    Morgan, D.O.5    Varmus, H.E.6
  • 23
    • 0029034939 scopus 로고
    • C-Src enhances the spreading of Src -/- Fibroblasts on fibronectin by a kinase-independent mechanism
    • Kaplan, K.B., J.R. Swedlow, D.O. Morgan, and H.E. Varmus. 1995. C-Src enhances the spreading of Src -/- fibroblasts on fibronectin by a kinase-independent mechanism. Genes Dev. 9:1505-1517.
    • (1995) Genes Dev. , vol.9 , pp. 1505-1517
    • Kaplan, K.B.1    Swedlow, J.R.2    Morgan, D.O.3    Varmus, H.E.4
  • 24
    • 0026600087 scopus 로고
    • Changes in the migratory ability of human lung and skin fibroblasts during in vitro aging and in vivo cellular senescence
    • Kondo, H., and Y. Yonezawa. 1992. Changes in the migratory ability of human lung and skin fibroblasts during in vitro aging and in vivo cellular senescence. Mech. Ageing Dev. 63:223-233.
    • (1992) Mech. Ageing Dev. , vol.63 , pp. 223-233
    • Kondo, H.1    Yonezawa, Y.2
  • 25
    • 0029958894 scopus 로고    scopus 로고
    • Role of the nuclear localization sequence in fibroblast growth factor-1-stimulated mitogenic pathways
    • Lin, Y., S.Y. Yao, and J. Hawiger. 1996. Role of the nuclear localization sequence in fibroblast growth factor-1-stimulated mitogenic pathways. J. Biol. Chem. 271:5305-5308.
    • (1996) J. Biol. Chem. , vol.271 , pp. 5305-5308
    • Lin, Y.1    Yao, S.Y.2    Hawiger, J.3
  • 27
    • 0025186452 scopus 로고
    • Extension of the life-span of human endothelial cells by an interleukin-1-alpha antisense oligomer
    • Maier, J.A.M., P. Voulalas, D. Roeder, and T. Maciag. 1990. Extension of the life-span of human endothelial cells by an interleukin-1-alpha antisense oligomer. Science (Wash. DC). 249:1570-1574.
    • (1990) Science (Wash. DC) , vol.249 , pp. 1570-1574
    • Maier, J.A.M.1    Voulalas, P.2    Roeder, D.3    Maciag, T.4
  • 28
    • 0025881470 scopus 로고
    • Cloning of a complementary DNA fora protein-tyrosine kinase that specifically phosphorylates a negative regulatory site of p60C-src
    • Nada, S., M. Okada, A. Macauley, J.A. Cooper, and H. Nakagawa. 1991. Cloning of a complementary DNA fora protein-tyrosine kinase that specifically phosphorylates a negative regulatory site of p60C-src. Nature (Lond.). 351:69-72.
    • (1991) Nature (Lond.) , vol.351 , pp. 69-72
    • Nada, S.1    Okada, M.2    Macauley, A.3    Cooper, J.A.4    Nakagawa, H.5
  • 29
    • 0027019129 scopus 로고
    • Endothelial cell senescence inhibits unidirectional endothelialization in vitro
    • Niu, S. and T. Matsuda. 1992. Endothelial cell senescence inhibits unidirectional endothelialization in vitro. Cell Transplant. 1:355-364.
    • (1992) Cell Transplant , vol.1 , pp. 355-364
    • Niu, S.1    Matsuda, T.2
  • 31
    • 0026355723 scopus 로고
    • Csk - A protein-tyrosine kinase involved in regulation of Src family kinases
    • Okada, M., S. Nada, Y. Yamanashi, T. Yamamoto, and H. Nakagawa. 1991. Csk - A protein-tyrosine kinase involved in regulation of Src family kinases. J. Biol. Chem. 266:24249-24252.
    • (1991) J. Biol. Chem. , vol.266 , pp. 24249-24252
    • Okada, M.1    Nada, S.2    Yamanashi, Y.3    Yamamoto, T.4    Nakagawa, H.5
  • 32
    • 0028146852 scopus 로고
    • Global changes of gene expression at late G1/S boundary may occur in human IMR-90 diploid fibroblasts during senescence
    • Pang, J.H., and K.Y. Chen. 1994. Global changes of gene expression at late G1/S boundary may occur in human IMR-90 diploid fibroblasts during senescence. J. Cell. Physiol. 160:531-538.
    • (1994) J. Cell. Physiol. , vol.160 , pp. 531-538
    • Pang, J.H.1    Chen, K.Y.2
  • 33
    • 0025940264 scopus 로고
    • Cyl encodes a putative cytoplasmic tyrosine kinase lacking the conserved tyrosine autophosphorylation site (Y416src)
    • Partanen, J., E. Armstrong, M. Bergman, T.P. Makela, H. Hirvonen, K. Huebner, and K. Alitalo. 1991. Cyl encodes a putative cytoplasmic tyrosine kinase lacking the conserved tyrosine autophosphorylation site (Y416src). Oncogene. 6:2013-2018.
    • (1991) Oncogene , vol.6 , pp. 2013-2018
    • Partanen, J.1    Armstrong, E.2    Bergman, M.3    Makela, T.P.4    Hirvonen, H.5    Huebner, K.6    Alitalo, K.7
  • 34
    • 0028329583 scopus 로고
    • PDGF-BB induced chemotaxis is impaired in aged capillary endothelial cells
    • Phillips, G.D., and A.M. Stone. 1994. PDGF-BB induced chemotaxis is impaired in aged capillary endothelial cells. Mech. Ageing Dev. 73:189-196.
    • (1994) Mech. Ageing Dev. , vol.73 , pp. 189-196
    • Phillips, G.D.1    Stone, A.M.2
  • 35
    • 0000941395 scopus 로고
    • A review of recent research on cellular aging in culture
    • Phillips, P.D., and V.J. Cristofalo. 1987. A review of recent research on cellular aging in culture. Rev. Biol. Rev. Aging. 3:385-415.
    • (1987) Rev. Biol. Rev. Aging. , vol.3 , pp. 385-415
    • Phillips, P.D.1    Cristofalo, V.J.2
  • 36
    • 0020647035 scopus 로고
    • 125I] EGF binding ability is stable throughout the replicative life-span of WI-38 cells
    • 125I] EGF binding ability is stable throughout the replicative life-span of WI-38 cells. J. Cell. Physiol. 114:311-316.
    • (1983) J. Cell. Physiol. , vol.114 , pp. 311-316
    • Phillips, P.D.1    Kuhnle, E.2    Cristofalo, V.J.3
  • 37
    • 0001111837 scopus 로고
    • Expression of cell cycle-dependent genes in young and senescent WI38 fibroblasts
    • Rittling, S.R., K.M. Brooks, V.J. Cristofalo, and R. Baserga. 1986. Expression of cell cycle-dependent genes in young and senescent WI38 fibroblasts. Proc. Natl. Acad. Sci. USA. 83:3316-3320.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 3316-3320
    • Rittling, S.R.1    Brooks, K.M.2    Cristofalo, V.J.3    Baserga, R.4
  • 38
    • 0028331263 scopus 로고
    • Tyrosine kinase activity, cytoskeletal organization, and motility in human vascular endothelial cells
    • Romer, L.H., N. McLean, C.E. Turner, and K. Burridge. 1994. Tyrosine kinase activity, cytoskeletal organization, and motility in human vascular endothelial cells. Mol. Biol. Cell. 5:349-361.
    • (1994) Mol. Biol. Cell , vol.5 , pp. 349-361
    • Romer, L.H.1    McLean, N.2    Turner, C.E.3    Burridge, K.4
  • 39
    • 0026568155 scopus 로고
    • Molecular cloning and expression of chicken C-terminal src kinase: Lack of stable association with c-src protein
    • Sabe, H., B. Knudsen, M. Okada, S. Nada, H. Nakagawa, and H. Hanafusa. 1992. Molecular cloning and expression of chicken C-terminal src kinase: Lack of stable association with c-src protein. Proc. Natl. Acad. Sci. USA. 89:2190-2194.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 2190-2194
    • Sabe, H.1    Knudsen, B.2    Okada, M.3    Nada, S.4    Nakagawa, H.5    Hanafusa, H.6
  • 40
    • 0024077722 scopus 로고
    • Autocrine activities of basic fibroblast growth factor: Regulation of endothelial cell movement, plasminogen activator synthesis, and DNA synthesis
    • Sato, Y., and D.B. Rifkin. 1988. Autocrine activities of basic fibroblast growth factor: regulation of endothelial cell movement, plasminogen activator synthesis, and DNA synthesis. J. Cell Biol. 107:1199-1205.
    • (1988) J. Cell Biol. , vol.107 , pp. 1199-1205
    • Sato, Y.1    Rifkin, D.B.2
  • 41
    • 0028122650 scopus 로고
    • Focal adhesion kinase and associated proteins
    • Schaller, M.D., and J.T. Parsons. 1994. Focal adhesion kinase and associated proteins. Curr. Opin. Cell Biol. 6:705-710.
    • (1994) Curr. Opin. Cell Biol. , vol.6 , pp. 705-710
    • Schaller, M.D.1    Parsons, J.T.2
  • 42
    • 0025052004 scopus 로고
    • Repression of c-fos transcription and an altered genetic program in senescent human fibroblasts
    • Seshadri, T., and J. Campisi. 1990. Repression of c-fos transcription and an altered genetic program in senescent human fibroblasts. Science (Wash. DC). 247:205-209.
    • (1990) Science (Wash. DC) , vol.247 , pp. 205-209
    • Seshadri, T.1    Campisi, J.2
  • 43
    • 0025120206 scopus 로고
    • Growth inhibiting effect of tumor necrosis factor on human umbilical vein endothelial cells is enhanced with advancing age in vitro
    • Shimada, Y., K. Kaji, H. Ito, K. Noda, and M. Matsuo. 1990. Growth inhibiting effect of tumor necrosis factor on human umbilical vein endothelial cells is enhanced with advancing age in vitro. J. Cell. Physiol. 142:31-38.
    • (1990) J. Cell. Physiol. , vol.142 , pp. 31-38
    • Shimada, Y.1    Kaji, K.2    Ito, H.3    Noda, K.4    Matsuo, M.5
  • 45
    • 0029045815 scopus 로고
    • Specific and redundant roles of Src and Fyn in organizing the cytoskeleton
    • Thomas, S.M., P. Soriano, and A. Imamoto. 1995. Specific and redundant roles of Src and Fyn in organizing the cytoskeleton. Nature (Lond.). 376: 267-271.
    • (1995) Nature (Lond.) , vol.376 , pp. 267-271
    • Thomas, S.M.1    Soriano, P.2    Imamoto, A.3
  • 46
    • 0020574001 scopus 로고
    • Human endothelial cells: Use of heparin in cloning and long-term serial cultivation
    • Thornton, S.C., S.N. Mueller, and E.M. Levine. 1983. Human endothelial cells: Use of heparin in cloning and long-term serial cultivation. Science (Wash. DC). 222:623-625.
    • (1983) Science (Wash. DC) , vol.222 , pp. 623-625
    • Thornton, S.C.1    Mueller, S.N.2    Levine, E.M.3
  • 48
    • 0028328846 scopus 로고
    • Dual mode of signal transduction by externally added acidic fibroblast growth factor
    • Wiedlocha, A., P.O. Falnes, I.H. Madshus, K. Sandvig, and S. Olsnes. 1994. Dual mode of signal transduction by externally added acidic fibroblast growth factor. Cell. 76:1039-1051.
    • (1994) Cell , vol.76 , pp. 1039-1051
    • Wiedlocha, A.1    Falnes, P.O.2    Madshus, I.H.3    Sandvig, K.4    Olsnes, S.5
  • 49
    • 0027419589 scopus 로고
    • Cortactin, an 80/85-kilodalton pp60src substrate, is a filamentous actin-binding protein enriched in the cell cortex
    • Wu, H., and J.T. Parsons. 1993. Cortactin, an 80/85-kilodalton pp60src substrate, is a filamentous actin-binding protein enriched in the cell cortex. J. Cell Biol. 120:1417-1426.
    • (1993) J. Cell Biol. , vol.120 , pp. 1417-1426
    • Wu, H.1    Parsons, J.T.2
  • 50
    • 0025940103 scopus 로고
    • Identification and characterization of a novel cytoskeleton-associated pp60src substrate
    • Wu, H., A.B. Reynolds, S.B. Kanner, R.R. Vines, and J.T. Parsons. 1991. Identification and characterization of a novel cytoskeleton-associated pp60src substrate. Mol. Cell. Biol. 11:5113-5124.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 5113-5124
    • Wu, H.1    Reynolds, A.B.2    Kanner, S.B.3    Vines, R.R.4    Parsons, J.T.5
  • 51
    • 0027286319 scopus 로고
    • Long term growth factor exposure and differential tyrosine phosphorylation are required for DNA synthesis in BALB/c 3T3 cells
    • Zhan, X., X. Hu, R. Friesel, and T. Maciag. 1993. Long term growth factor exposure and differential tyrosine phosphorylation are required for DNA synthesis in BALB/c 3T3 cells. J. Biol. Chem. 268:9611-9620.
    • (1993) J. Biol. Chem. , vol.268 , pp. 9611-9620
    • Zhan, X.1    Hu, X.2    Friesel, R.3    Maciag, T.4
  • 52
    • 0027423238 scopus 로고
    • Murine cortactin is phosphorylated in response to fibroblast growth factor-1 on tyrosine residues late in the G1 phase of the BALB/c 3T3 cell cycle
    • Zhan, X., X. Hu, B. Hampton, W.H. Burgess, R. Friesel, and T. Maciag. 1993. Murine cortactin is phosphorylated in response to fibroblast growth factor-1 on tyrosine residues late in the G1 phase of the BALB/c 3T3 cell cycle. J. Biol. Chem. 268:24427-24431.
    • (1993) J. Biol. Chem. , vol.268 , pp. 24427-24431
    • Zhan, X.1    Hu, X.2    Hampton, B.3    Burgess, W.H.4    Friesel, R.5    Maciag, T.6
  • 53
    • 0027967279 scopus 로고
    • Association of fibroblast growth factor receptor-1 with c-Src correlates with association between c-Src and cortactin
    • Zhan, X., C. Plourde, X. Hu, R. Friesel, and T. Maciag. 1994. Association of fibroblast growth factor receptor-1 with c-Src correlates with association between c-Src and cortactin. J. Biol. Chem. 269:20221-20224.
    • (1994) J. Biol. Chem. , vol.269 , pp. 20221-20224
    • Zhan, X.1    Plourde, C.2    Hu, X.3    Friesel, R.4    Maciag, T.5


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