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Volumn 70, Issue 11, 2010, Pages 4749-4758

ARF suppresses tumor angiogenesis through translational control of VEGFA mRNA

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR; MESSENGER RNA; NUCLEOPHOSMIN; PROTEIN P19 ARF; PROTEIN P53; UNCLASSIFIED DRUG; VASCULOTROPIN A;

EID: 77953168825     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-10-0368     Document Type: Article
Times cited : (34)

References (48)
  • 1
    • 0029587551 scopus 로고
    • Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest
    • Quelle DE, Zindy F, Ashmun RA, Sherr CJ. Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest. Cell 1995;83:993-1000.
    • (1995) Cell , vol.83 , pp. 993-1000
    • Quelle, D.E.1    Zindy, F.2    Ashmun, R.A.3    Sherr, C.J.4
  • 2
    • 0027769876 scopus 로고
    • A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
    • Serrano M, Hannon GJ, Beach D. A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. Nature 1993; 366:704-707
    • (1993) Nature , vol.366 , pp. 704-707
    • Serrano, M.1    Hannon, G.J.2    Beach, D.3
  • 3
    • 0035487104 scopus 로고    scopus 로고
    • The INK4a/ARF network in tumour suppression
    • Sherr CJ. The INK4a/ARF network in tumour suppression. Nat Rev Mol Cell Biol 2001;2:731-737
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 731-737
    • Sherr, C.J.1
  • 4
    • 0030944985 scopus 로고    scopus 로고
    • Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
    • Serrano M, Lin AW, McCurrach ME, Beach D, Lowe SW. Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 1997;88:593-602.
    • (1997) Cell , vol.88 , pp. 593-602
    • Serrano, M.1    Lin, A.W.2    McCurrach, M.E.3    Beach, D.4    Lowe, S.W.5
  • 7
    • 0033588882 scopus 로고    scopus 로고
    • The INK4 family of cell cycle inhibitors in cancer
    • Roussel MF. The INK4 family of cell cycle inhibitors in cancer. Oncogene 1999;18:5311-5317
    • (1999) Oncogene , vol.18 , pp. 5311-5317
    • Roussel, M.F.1
  • 9
    • 0033521621 scopus 로고    scopus 로고
    • Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53
    • Honda R, Yasuda H. Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53. EMBO J 1999;18:22-27
    • (1999) EMBO J , vol.18 , pp. 22-27
    • Honda, R.1    Yasuda, H.2
  • 10
    • 0032984992 scopus 로고    scopus 로고
    • Mechanisms of p53-mediated apoptosis
    • Bates S, Vousden KH. Mechanisms of p53-mediated apoptosis. Cell Mol Life Sci 1999;55:28-37.
    • (1999) Cell Mol Life Sci , vol.55 , pp. 28-37
    • Bates, S.1    Vousden, K.H.2
  • 12
    • 0034665749 scopus 로고    scopus 로고
    • p53-independent functions of the p19(ARF) tumor suppressor
    • Weber JD, Jeffers JR, Rehg JE, et al. p53-independent functions of the p19(ARF) tumor suppressor. Genes Dev 2000;14:2358-2365
    • (2000) Genes Dev , vol.14 , pp. 2358-2365
    • Weber, J.D.1    Jeffers, J.R.2    Rehg, J.E.3
  • 13
    • 0037291204 scopus 로고    scopus 로고
    • Nucleolar Arf tumor suppressor inhibits ribosomal RNA processing
    • Sugimoto M, Kuo ML, Roussel MF, Sherr CJ. Nucleolar Arf tumor suppressor inhibits ribosomal RNA processing. Mol Cell 2003;11: 415-424
    • (2003) Mol Cell , vol.11 , pp. 415-424
    • Sugimoto, M.1    Kuo, M.L.2    Roussel, M.F.3    Sherr, C.J.4
  • 14
    • 1642499357 scopus 로고    scopus 로고
    • Physical and functional interactions of the Arf tumor suppressor protein with nucleophosmin/B23
    • Bertwistle D, Sugimoto M, Sherr CJ. Physical and functional interactions of the Arf tumor suppressor protein with nucleophosmin/B23. Mol Cell Biol 2004;24:985-996
    • (2004) Mol Cell Biol , vol.24 , pp. 985-996
    • Bertwistle, D.1    Sugimoto, M.2    Sherr, C.J.3
  • 15
    • 0345276485 scopus 로고    scopus 로고
    • Tumor suppressor ARF degrades B23, a nucleolar protein involved in ribosome biogenesis and cell proliferation
    • Itahana K, Bhat KP, Jin A, et al. Tumor suppressor ARF degrades B23, a nucleolar protein involved in ribosome biogenesis and cell proliferation. Mol Cell 2003;12:1151-1164
    • (2003) Mol Cell , vol.12 , pp. 1151-1164
    • Itahana, K.1    Bhat, K.P.2    Jin, A.3
  • 17
    • 0030816109 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth
    • Maxwell PH, Dachs GU, Gleadle JM, et al. Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth. Proc Natl Acad Sci U S A 1997; 94:8104-8109
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 8104-8109
    • Maxwell, P.H.1    Dachs, G.U.2    Gleadle, J.M.3
  • 18
    • 0035958932 scopus 로고    scopus 로고
    • The p14ARF tumor suppressor protein facilitates nucleolar sequestration of hypoxia-inducible factor-1α (HIF-1α) and inhibits HIF-1-mediated transcription
    • Fatyol K, Szalay AA. The p14ARF tumor suppressor protein facilitates nucleolar sequestration of hypoxia-inducible factor-1α (HIF-1α) and inhibits HIF-1-mediated transcription. J Biol Chem 2001; 276:28421-28429
    • (2001) J Biol Chem , vol.276 , pp. 28421-28429
    • Fatyol, K.1    Szalay, A.A.2
  • 19
    • 0037442417 scopus 로고    scopus 로고
    • Inhibition of colon tumor progression and angiogenesis by the Ink4a/Arf locus
    • Gibson SL, Dai CY, Lee HW, et al. Inhibition of colon tumor progression and angiogenesis by the Ink4a/Arf locus. Cancer Res 2003;63: 742-746
    • (2003) Cancer Res , vol.63 , pp. 742-746
    • Gibson, S.L.1    Dai, C.Y.2    Lee, H.W.3
  • 20
    • 0031039243 scopus 로고    scopus 로고
    • The biology of vascular endothelial growth factor
    • Ferrara N, Davis-Smyth T. The biology of vascular endothelial growth factor. Endocr Rev 1997;18:4-25.
    • (1997) Endocr Rev , vol.18 , pp. 4-25
    • Ferrara, N.1    Davis-Smyth, T.2
  • 21
    • 27944473690 scopus 로고    scopus 로고
    • VEGF as a key mediator of angiogenesis in cancer
    • Carmeliet P. VEGF as a key mediator of angiogenesis in cancer. Oncology 2005;69 Suppl 3:4-10.
    • (2005) Oncology , vol.69 , Issue.SUPPL. 3 , pp. 4-10
    • Carmeliet, P.1
  • 22
    • 0037967272 scopus 로고    scopus 로고
    • Tumorigenesis and the angiogenic switch
    • Bergers G, Benjamin LE. Tumorigenesis and the angiogenic switch. Nat Rev Cancer 2003;3:401-410
    • (2003) Nat Rev Cancer , vol.3 , pp. 401-410
    • Bergers, G.1    Benjamin, L.E.2
  • 23
    • 0032537757 scopus 로고    scopus 로고
    • Regulation of vascular endothelial growth factor (VEGF) expression is mediated by internal initiation of translation and alternative initiation of transcription
    • Akiri G, Nahari D, Finkelstein Y, Le SY, Elroy-Stein O, Levi BZ. Regulation of vascular endothelial growth factor (VEGF) expression is mediated by internal initiation of translation and alternative initiation of transcription. Oncogene 1998;17:227-236 (Pubitemid 28371896)
    • (1998) Oncogene , vol.17 , Issue.2 , pp. 227-236
    • Akiri, G.1    Nahari, D.2    Finkelstein, Y.3    Le, S.-Y.4    Elroy-Stein, O.5    Levi, B.-Z.6
  • 24
    • 2442559239 scopus 로고    scopus 로고
    • Control of the vascular endothelial growth factor internal ribosome entry site (IRES) activity and translation initiation by alternatively spliced coding sequences
    • Bornes S, Boulard M, Hieblot C, et al. Control of the vascular endothelial growth factor internal ribosome entry site (IRES) activity and translation initiation by alternatively spliced coding sequences. J Biol Chem 2004;279:18717-18726
    • (2004) J Biol Chem , vol.279 , pp. 18717-18726
    • Bornes, S.1    Boulard, M.2    Hieblot, C.3
  • 25
    • 33847058369 scopus 로고    scopus 로고
    • Translational induction of VEGF internal ribosome entry site elements during the early response to ischemic stress
    • Bornes S, Prado-Lourenco L, Bastide A, et al. Translational induction of VEGF internal ribosome entry site elements during the early response to ischemic stress. Circ Res 2007;100:305-308
    • (2007) Circ Res , vol.100 , pp. 305-308
    • Bornes, S.1    Prado-Lourenco, L.2    Bastide, A.3
  • 27
    • 14644401017 scopus 로고    scopus 로고
    • N-terminal polyubiquitination of the ARF tumor suppressor, a natural lysine-less protein
    • Kuo ML, den Besten W, Sherr CJ. N-terminal polyubiquitination of the ARF tumor suppressor, a natural lysine-less protein. Cell Cycle 2004;3:1367-1369 (Pubitemid 40310668)
    • (2004) Cell Cycle , vol.3 , Issue.11 , pp. 1367-1369
    • Kuo, M.-L.1    Den Besten, W.2    Sherr, C.J.3
  • 28
    • 0036268259 scopus 로고    scopus 로고
    • Phosphorylation of initiation factor-2 α is required for activation of internal translation initiation during cell differentiation
    • Gerlitz G, Jagus R, Elroy-Stein O. Phosphorylation of initiation factor-2 α is required for activation of internal translation initiation during cell differentiation. Eur J Biochem 2002;269:2810-2819
    • (2002) Eur J Biochem , vol.269 , pp. 2810-2819
    • Gerlitz, G.1    Jagus, R.2    Elroy-Stein, O.3
  • 29
    • 44349115450 scopus 로고    scopus 로고
    • Hzf regulates adipogenesis through translational control of C/EBPα
    • Kawagishi H, Wakoh T, Uno H, et al. Hzf regulates adipogenesis through translational control of C/EBPα. EMBO J 2008;27: 1481-1490
    • (2008) EMBO J , vol.27 , pp. 1481-1490
    • Kawagishi, H.1    Wakoh, T.2    Uno, H.3
  • 30
    • 0034235047 scopus 로고    scopus 로고
    • Wild-type p53 suppresses angiogenesis in human leiomyosarcoma and synovial sarcoma by transcriptional suppression of vascular endothelial growth factor expression
    • Zhang L, Yu D, Hu M, et al. Wild-type p53 suppresses angiogenesis in human leiomyosarcoma and synovial sarcoma by transcriptional suppression of vascular endothelial growth factor expression. Cancer Res 2000;60:3655-3661 (Pubitemid 30482190)
    • (2000) Cancer Research , vol.60 , Issue.13 , pp. 3655-3661
    • Zhang, L.1    Yu, D.2    Hu, M.3    Xiong, S.4    Lang, A.5    Ellis, L.M.6    Pollock, R.E.7
  • 31
    • 6344288701 scopus 로고    scopus 로고
    • ARF impedes NPM/B23 shuttling in an Mdm2-sensitive tumor suppressor pathway
    • Brady SN, Yu Y, Maggi LB, Jr., Weber JD. ARF impedes NPM/B23 shuttling in an Mdm2-sensitive tumor suppressor pathway. Mol Cell Biol 2004;24:9327-9338
    • (2004) Mol Cell Biol , vol.24 , pp. 9327-9338
    • Brady, S.N.1    Yu, Y.2    Maggi Jr., L.B.3    Weber, J.D.4
  • 32
    • 13444287955 scopus 로고    scopus 로고
    • Nucleophosmin (B23) targets ARF to nucleoli and inhibits its function
    • Korgaonkar C, Hagen J, Tompkins V, et al. Nucleophosmin (B23) targets ARF to nucleoli and inhibits its function. Mol Cell Biol 2005; 25:1258-1271
    • (2005) Mol Cell Biol , vol.25 , pp. 1258-1271
    • Korgaonkar, C.1    Hagen, J.2    Tompkins, V.3
  • 33
    • 27944490875 scopus 로고    scopus 로고
    • VEGF as a therapeutic target in cancer
    • Ferrara N. VEGF as a therapeutic target in cancer. Oncology 2005;69 Suppl 3:11-16
    • (2005) Oncology , vol.69 , Issue.SUPPL. 3 , pp. 11-16
    • Ferrara, N.1
  • 34
    • 11144354392 scopus 로고    scopus 로고
    • Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer
    • Willett CG, Boucher Y, di Tomaso E, et al. Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer. Nat Med 2004;10:145-147
    • (2004) Nat Med , vol.10 , pp. 145-147
    • Willett, C.G.1    Boucher, Y.2    Di Tomaso, E.3
  • 35
    • 34547235967 scopus 로고    scopus 로고
    • A post-transcriptional pathway represses monocyte VEGF-A expression and angiogenic activity
    • Ray PS, Fox PL. A post-transcriptional pathway represses monocyte VEGF-A expression and angiogenic activity. EMBO J 2007;26: 3360-3372
    • (2007) EMBO J , vol.26 , pp. 3360-3372
    • Ray, P.S.1    Fox, P.L.2
  • 36
    • 58249106363 scopus 로고    scopus 로고
    • The VEGF IRESes are differentially susceptible to translation inhibition by miR-16
    • Karaa ZS, Iacovoni JS, Bastide A, Lacazette E, Touriol C, Prats H. The VEGF IRESes are differentially susceptible to translation inhibition by miR-16. RNA 2009;15:249-254
    • (2009) RNA , vol.15 , pp. 249-254
    • Karaa, Z.S.1    Iacovoni, J.S.2    Bastide, A.3    Lacazette, E.4    Touriol, C.5    Prats, H.6
  • 38
    • 0037428129 scopus 로고    scopus 로고
    • Dyskeratosis congenita and cancer in mice deficient in ribosomal RNA modification
    • Ruggero D, Grisendi S, Piazza F, et al. Dyskeratosis congenita and cancer in mice deficient in ribosomal RNA modification. Science 2003;299:259-262
    • (2003) Science , vol.299 , pp. 259-262
    • Ruggero, D.1    Grisendi, S.2    Piazza, F.3
  • 39
    • 33646543044 scopus 로고    scopus 로고
    • Impaired control of IRES-mediated translation in X-linked dyskeratosis congenita
    • Yoon A, Peng G, Brandenburger Y, et al. Impaired control of IRES-mediated translation in X-linked dyskeratosis congenita. Science 2006;312:902-906
    • (2006) Science , vol.312 , pp. 902-906
    • Yoon, A.1    Peng, G.2    Brandenburger, Y.3
  • 40
    • 33846002755 scopus 로고    scopus 로고
    • Physical and functional interaction of the p14ARF tumor suppressor with ribosomes
    • Rizos H, McKenzie HA, Ayub AL, et al. Physical and functional interaction of the p14ARF tumor suppressor with ribosomes. J Biol Chem 2006;281:38080-38088
    • (2006) J Biol Chem , vol.281 , pp. 38080-38088
    • Rizos, H.1    McKenzie, H.A.2    Ayub, A.L.3
  • 41
    • 33747819484 scopus 로고    scopus 로고
    • Divorcing ARF and p53: An unsettled case
    • Sherr CJ. Divorcing ARF and p53: an unsettled case. Nat Rev Cancer 2006;6:663-673
    • (2006) Nat Rev Cancer , vol.6 , pp. 663-673
    • Sherr, C.J.1
  • 42
    • 19344364856 scopus 로고    scopus 로고
    • p19Arf suppresses growth, progression, and metastasis of Hras-driven carcinomas through p53-dependent and -independent pathways
    • Kelly-Spratt KS, Gurley KE, Yasui Y, Kemp CJ. p19Arf suppresses growth, progression, and metastasis of Hras-driven carcinomas through p53-dependent and -independent pathways. PLoS Biol 2004;2:E242.
    • (2004) PLoS Biol , vol.2
    • Kelly-Spratt, K.S.1    Gurley, K.E.2    Yasui, Y.3    Kemp, C.J.4
  • 43
    • 43749106257 scopus 로고    scopus 로고
    • p19/Arf and p53 suppress sentinel lymph node lymphangiogenesis and carcinoma metastasis
    • Ruddell A, Kelly-Spratt KS, Furuya M, Parghi SS, Kemp CJ. p19/Arf and p53 suppress sentinel lymph node lymphangiogenesis and carcinoma metastasis. Oncogene 2008;27:3145-3155
    • (2008) Oncogene , vol.27 , pp. 3145-3155
    • Ruddell, A.1    Kelly-Spratt, K.S.2    Furuya, M.3    Parghi, S.S.4    Kemp, C.J.5
  • 45
    • 0037133685 scopus 로고    scopus 로고
    • The Arf tumor suppressor gene promotes hyaloid vascular regression during mouse eye development
    • McKeller RN, Fowler JL, Cunningham JJ, et al. The Arf tumor suppressor gene promotes hyaloid vascular regression during mouse eye development. Proc Natl Acad Sci U S A 2002;99:3848-3853
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 3848-3853
    • McKeller, R.N.1    Fowler, J.L.2    Cunningham, J.J.3
  • 46
    • 23844516784 scopus 로고    scopus 로고
    • Arf-dependent regulation of Pdgf signaling in perivascular cells in the developing mouse eye
    • Silva RL, Thornton JD, Martin AC, et al. Arf-dependent regulation of Pdgf signaling in perivascular cells in the developing mouse eye. EMBO J 2005;24:2803-2814
    • (2005) EMBO J , vol.24 , pp. 2803-2814
    • Silva, R.L.1    Thornton, J.D.2    Martin, A.C.3
  • 47
    • 33747488399 scopus 로고    scopus 로고
    • PML inhibits HIF-1α translation and neoangiogenesis through repression of mTOR
    • Bernardi R, Guernah I, Jin D, et al. PML inhibits HIF-1α translation and neoangiogenesis through repression of mTOR. Nature 2006; 442:779-785
    • (2006) Nature , vol.442 , pp. 779-785
    • Bernardi, R.1    Guernah, I.2    Jin, D.3
  • 48
    • 3543148255 scopus 로고    scopus 로고
    • N-terminal polyubiquitination and degradation of the Arf tumor suppressor
    • Kuo ML, den Besten W, Bertwistle D, Roussel MF, Sherr CJ. N-terminal polyubiquitination and degradation of the Arf tumor suppressor. Genes Dev 2004;18:1862-1874
    • (2004) Genes Dev , vol.18 , pp. 1862-1874
    • Kuo, M.L.1    Den Besten, W.2    Bertwistle, D.3    Roussel, M.F.4    Sherr, C.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.