Impaired angiogenesis in aging myocardial microvascular endothelial cells is associated with reduced importin α and decreased nuclear transport of HIF1α: Mechanistic implications

Journal of Physiology and Pharmacology

Volumn 61, Issue 2, 2010, Pages 133-139

  Ahluwalia, A ^a,b   Narula, J ^a,b   Jones, M K ^a,b   Deng, X ^a,b   Tarnawski, A S ^a,b  

^a VA LONG BEACH HEALTHCARE SYSTEM   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Aging; Angiogenesis; Hypoxia inducible factor 1 ; Importin ; Myocardial microvascular endothelial cells; Vascular endothelial growth factor

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; KARYOPHERIN ALPHA; VASCULOTROPIN; VASCULOTROPIN A;

ANGIOGENESIS; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL AGING; CELL ISOLATION; CELL NUCLEUS; CONTROLLED STUDY; ENDOTHELIUM CELL; FISCHER 344 RAT; GENE ACTIVATION; HYPOTHESIS; IN VITRO STUDY; MICROVASCULARIZATION; NONHUMAN; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN TRANSPORT; RAT; RECEPTOR DOWN REGULATION; AGE; AGING; ANIMAL; CYTOPLASM; DOWN REGULATION; GENETICS; HEART MUSCLE; METABOLISM; MICROVASCULATURE; PROTEIN BINDING; VASCULAR ENDOTHELIUM;

AGE FACTORS; AGING; ALPHA KARYOPHERINS; ANIMALS; CELL NUCLEUS; CYTOPLASM; DOWN-REGULATION; ENDOTHELIUM, VASCULAR; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICROVESSELS; MYOCARDIUM; NEOVASCULARIZATION, PHYSIOLOGIC; PROTEIN BINDING; PROTEIN TRANSPORT; RATS; RATS, INBRED F344; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 77955914268     PISSN: 08675910     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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