Dendritic cells the tumor microenvironment and the challenges for an effective antitumor vaccination

Journal of Biomedicine and Biotechnology

Volumn 2012, Issue , 2012, Pages

  Benencia, Fabian ^a,b,c   Sprague, Leslee ^a   McGinty, John ^c   Pate, Michelle ^c   Muccioli, Maria ^b  

^a Ohio University   (United States)

^b OHIO UNIVERSITY   (United States)

^c OHIO UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; ANGIOGENIC FACTOR; ANGIOGENIN; BASIC FIBROBLAST GROWTH FACTOR RECEPTOR; CD11 ANTIGEN; DACLIZUMAB; DENILEUKIN DIFTITOX; HEPARANASE; INTERLEUKIN 10; LENTIVIRUS VECTOR; MATRIX METALLOPROTEINASE; PROSTAGLANDIN E2; RETROVIRUS VECTOR; SIPULEUCEL T; VASCULOTROPIN; CANCER VACCINE;

CANCER GROWTH; CANCER IMMUNIZATION; CASTRATION RESISTANT PROSTATE CANCER; CELL ACTIVATION; CELL FUNCTION; CELL PHAGOCYTOSIS; DENDRITIC CELL; DRUG EFFICACY; HUMAN; IMMUNE RESPONSE; IMMUNE SYSTEM; IMMUNOCOMPETENT CELL; INFLAMMATION; MONOCYTE; NONHUMAN; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); POXVIRUS; REVIEW; T LYMPHOCYTE; TUMOR GROWTH; TUMOR MICROENVIRONMENT; ANIMAL; IMMUNOLOGY;

ANIMALS; CANCER VACCINES; DENDRITIC CELLS; HUMANS; TUMOR MICROENVIRONMENT;

EID: 84859717471     PISSN: 11107243     EISSN: 11107251     Source Type: Journal    
DOI: 10.1155/2012/425476     Document Type: Review

References (194)

1. Bonasio R., von Andrian U. H., Generation, migration and function of circulating dendritic cells Current Opinion in Immunology 2006 18 4 503 511 (Pubitemid 43947581)
2. Lanzavecchia A., Sallusto F., The instructive role of dendritic cells on T cell responses: lineages, plasticity and kinetics Current Opinion in Immunology 2001 13 3 291 298 (Pubitemid 32537700)
3. Banchereau J., Briere F., Caux C., Davoust J., Lebecque S., Liu Y. J., Pulendran B., Palucka K., Immunobiology of dendritic cells Annual Review of Immunology 2000 18 767 811 (Pubitemid 30365397)
4. Timmerman J. M., Levy R., Dendritic cell vaccines for cancer immunotherapy Annual Review of Medicine 1999 50 507 529 (Pubitemid 29117080)
5. Riboldi E., Musso T., Moroni E., Urbinati C., Bernasconi S., Rusnati M., Adorini L., Presta M., Sozzani S., Cutting edge: proangiogenic properties of alternatively activated dendritic cells Journal of Immunology 2005 175 5 2788 2792 (Pubitemid 41170494)
6. Feldmann M., Maini R. N., Discovery of TNF- as a therapeutic target in rheumatoid arthritis: preclinical and clinical studies Joint Bone Spine 2002 69 1 12 18 (Pubitemid 34123340)
7. Kapsenberg M. L., Dendritic-cell control of pathogen-driven T-cell polarization Nature Reviews Immunology 2003 3 12 984 993 (Pubitemid 37521540)
8. Doherty T. M., Fisher E. A., Arditi M., TLR signaling and trapped vascular dendritic cells in the development of atherosclerosis Trends in Immunology 2006 27 5 222 227
9. Snchez-Snchez N., Riol-Blanco L., De La Rosa G., Puig-Krger A., Garca-Bordas J., Martn D., Longo N., Cuadrado A., Cabaas C., Corb A. L., Snchez-Mateos P., Rodrguez-Fernndez J. L., Chemokine receptor CCR7 induces intracellular signaling that inhibits apoptosis of mature dendritic cells Blood 2004 104 3 619 625 (Pubitemid 38970552)
10. Kadowaki N., Dendritic cellsa conductor of T cell differentiation Allergology International 2007 56 3 193 199 (Pubitemid 47442386)
11. Liu K., Nussenzweig M. C., Origin and development of dendritic cells Immunological Reviews 2010 234 1 45 54
12. Shortman K., Heath W. R., The CD8 + dendritic cell subset Immunological Reviews 2010 234 1 18 31
13. Liu K., Victora G. D., Schwickert T. A., Guermonprez P., Meredith M. M., Yao K., Chu F. F., Randolph G. J., Rudensky A. Y., Nussenzweig M., In vivo analysis of dendritic cell development and homeostasis Science 2009 324 5925 392 397
14. Liu K., Waskow C., Liu X., Yao K., Hoh J., Nussenzweig M., Origin of dendritic cells in peripheral lymphoid organs of mice Nature Immunology 2007 8 6 578 583 (Pubitemid 46785121)
15. Dudziak D., Kamphorst A. O., Heidkamp G. F., Buchholz V. R., Trumpfheller C., Yamazaki S., Cheong C., Liu K., Lee H. W., Chae G. P., Steinman R. M., Nussenzweig M. C., Differential antigen processing by dendritic cell subsets in vivo Science 2007 315 5808 107 111 (Pubitemid 46196991)
16. Crozat K., Guiton R., Contreras V., Feuillet V., Dutertre C. A., Ventre E., Manh T. P. V., Baranek T., Storset A. K., Marvel J., Boudinot P., Hosmalin A., Schwartz-Cornil I., Dalod M., The XC chemokine receptor 1 is a conserved selective marker of mammalian cells homologous to mouse CD8 + dendritic cells Journal of Experimental Medicine 2010 207 6 1283 1292
17. Crozat K., Tamoutounour S., Vu Manh T.-P., Fossum E., Luche H., Ardouin L., Guilliams M., Azukizawa H., Bogen B., Malissen B., Henri S., Dalod M., Cutting edge: expression of XCR1 defines mouse lymphoid-tissue resident and migratory dendritic cells of the CD8 + type Journal of Immunology 2011 187 9 4411 4415
18. Hildner K., Edelson B. T., Purtha W. E., Diamond M., Matsushita H., Kohyama M., Calderon B., Schraml B. U., Unanue E. R., Diamond M. S., Schreiber R. D., Murphy T. L., Murphy K. M., Batf3 deficiency reveals a critical role for CD8 + dendritic cells in cytotoxic T cell immunity Science 2008 322 5904 1097 1100
19. Waskow C., Liu K., Darrasse-Jze G., Guermonprez P., Ginhoux F., Merad M., Shengelia T., Yao K., Nussenzweig M., The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues Nature Immunology 2008 9 6 676 683 (Pubitemid 351712638)
20. Nagao K., Ginhoux F., Leitner W. W., Motegi S. I., Bennett C. L., Clausen B. E., Merad M., Udey M. C., Murine epidermal Langerhans cells and langerin-expressing dermal dendritic cells are unrelated and exhibit distinct functions Proceedings of the National Academy of Sciences of the United States of America 2009 106 9 3312 3317
21. Edelson B. T., Wumesh K. C., Juang R., Kohyama M., Benoit L. A., Klekotka P. A., Moon C., Albring J. C., Ise W., Michael D. G., Bhattacharya D., Stappenbeck T. S., Holtzman M. J., Sung S. S. J., Murphy T. L., Hildner K., Murphy K. M., Peripheral CD103 + dendritic cells form a unified subset developmentally related to CD8 + conventional dendritic cells Journal of Experimental Medicine 2010 207 4 823 836
22. Liu Y. J., IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors Annual Review of Immunology 2005 23 275 306
23. Penna G., Vulcano M., Sozzani S., Adorini L., Differential migration behavior and chemokine production by myeloid and plasmacytoid dendritic cells Human Immunology 2002 63 12 1164 1171 (Pubitemid 36025991)
24. Lutz M. B., Kukutsch N., Ogilvie A. L. J., Rner S., Koch F., Romani N., Schuler G., An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow Journal of Immunological Methods 1999 223 1 77 92 (Pubitemid 29096240)
25. Inaba K., Inaba M., Romani N., Aya H., Deguchi M., Ikehara S., Muramatsu S., Steinman R. M., Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor Journal of Experimental Medicine 1992 176 6 1693 1702
26. Masurier C., Pioche-Durieu C., Colombo B. M., Lacave R., Lemoine F. M., Klatzmann D., Guigon M., Immunophenotypical and functional heterogeneity of dendritic cells generated from murine bone marrow cultured with different cytokine combinations: implications for anti-tumoral cell therapy Immunology 1999 96 4 569 577 (Pubitemid 29179795)
27. Gilboa E., Vieweg J., Cancer immunotherapy with mRNA-transfected dendritic cells Immunological Reviews 2004 199 251 263 (Pubitemid 38744521)
28. Grolleau-Julius A., Abernathy L., Harning E., Yung R. L., Mechanisms of murine dendritic cell antitumor dysfunction in aging Cancer Immunology, Immunotherapy 2009 58 12 1935 1939
29. MacAry P. A., Too C. T., Dai X., Targeting tumours by adoptive transfer of immune cells Clinical and Experimental Pharmacology and Physiology 2006 33 5-6 569 574
30. Bianco N. R., Kim S. H., Morelli A. E., Robbins P. D., Modulation of the immune response using dendritic cell-derived exosomes Methods in Molecular Biology 2007 380 443 455 (Pubitemid 350183346)
31. Murdoch C., Muthana M., Coffelt S. B., Lewis C. E., The role of myeloid cells in the promotion of tumour angiogenesis Nature Reviews Cancer 2008 8 8 618 631
32. Simon J. C., Hara H., Denfeld R. W., Martin S., UVB-irradiated dendritic cells induce nonproliferating, regulatory type T cells Skin Pharmacology and Applied Skin Physiology 2002 15 5 330 334
33. Yamagami S., Usui T., Amano S., Ebihara N., Bone marrow-derived cells in mouse and human cornea Cornea 2005 24 8 S71 S74
34. Yrlid U., Svensson M., Johansson C., Wick M. J., Salmonella infection of bone marrow-derived macrophages and dendritic cells: influence on antigen presentation and initiating an immune response FEMS Immunology and Medical Microbiology 2000 27 4 313 320 (Pubitemid 30155826)
35. Maraskovsky E., Brasel K., Teepe M., Roux E. R., Lyman S. D., Shortman K., McKenna H. J., Dramatic increase in the number of functionally mature dendritic cells in Flt3 ligand-treated mice: multiple dendritic cell subpopulations identified Journal of Experimental Medicine 1996 184 5 1953 1962 (Pubitemid 26404485)
36. Brawand P., Fitzpatrick D. R., Greenfield B. W., Brasel K., Maliszewski C. R., De Smedt T., Murine plasmacytoid pre-dendritic cells generated from Flt3 ligand-supplemented bone marrow cultures are immature APCs Journal of Immunology 2002 169 12 6711 6719 (Pubitemid 36899255)
37. Hieronymus T., Gust T. C., Kirsch R. D., Jorgas T., Blendinger G., Goncharenko M., Supplitt K., Rose-John S., Mller A. M., Zenke M., Progressive and controlled development of mouse dendritic cells from Flt3 + CD11b + progenitors in vitro Journal of Immunology 2005 174 5 2552 2562 (Pubitemid 40279668)
38. Serbina N. V., Salazar-Mather T. P., Biron C. A., Kuziel W. A., Pamer E. G., TNF/iNOS-producing dendritic cells mediate innate immune defense against bacterial infection Immunity 2003 19 1 59 70 (Pubitemid 36859901)
39. Domnguez P. M., Ardavn C., Differentiation and function of mouse monocyte-derived dendritic cells in steady state and inflammation Immunological Reviews 2010 234 1 90 104
40. Engel D., Dobrindt U., Tittel A., Peters P., Maurer J., Gtgemann I., Kaissling B., Kuziel W., Jung S., Kurts C., Tumor necrosis factor alpha- and inducible nitric oxide synthase-producing dendritic cells are rapidly recruited to the bladder in urinary tract infection but are dispensable for bacterial clearance Infection and Immunity 2006 74 11 6100 6107 (Pubitemid 44657388)
41. Nakano H., Lin K. L., Yanagita M., Charbonneau C., Cook D. N., Kakiuchi T., Gunn M. D., Blood-derived inflammatory dendritic cells in lymph nodes stimulate acute T helper type 1 immune responses Nature Immunology 2009 10 4 394 402
42. Shortman K., Naik S. H., Steady-state and inflammatory dendritic-cell development Nature Reviews Immunology 2007 7 1 19 30 (Pubitemid 46020824)
43. Varol C., Landsman L., Fogg D. K., Greenshtein L., Gildor B., Margalit R., Kalchenko V., Geissmann F., Jung S., Monocytes give rise to mucosal, but not splenic, conventional dendritic cells Journal of Experimental Medicine 2007 204 1 171 180 (Pubitemid 46148767)
44. Landsman L., Varol C., Jung S., Distinct differentiation potential of blood monocyte subsets in the lung Journal of Immunology 2007 178 4 2000 2007 (Pubitemid 46233396)
45. Jakubzick C., Tacke F., Ginhoux F., Wagers A. J., Van Rooijen N., Mack M., Merad M., Randolph G. J., Blood monocyte subsets differentially give rise to CD103 + and CD103 - pulmonary dendritic cell populations Journal of Immunology 2008 180 5 3019 3027
46. Taieb J., Chaput N., Ménard C., Apetoh L., Ullrich E., Bonmort M., Péquignot M., Casares N., Terme M., Flament C., Opolon P., Lecluse Y., Métivier D., Tomasello E., Vivier E., Ghiringhelli F., Martin F., Klatzmann D., Poynard T., Tursz T., Raposo G., Yagita H., Ryffel B., Kroemer G., Zitvogel L., A novel dendritic cell subset involved in tumor immunosurveillance Nature Medicine 2006 12 2 214 219 (Pubitemid 43214748)
47. Chauvin C., Philippeau J. M., Hémont C., Hubert F. X., Wittrant Y., Lamoureux F., Trinité B., Heymann D., Rédini F., Josien R., Killer dendritic cells link innate and adaptive immunity against established osteosarcoma in rats Cancer Research 2008 68 22 9433 9440
48. Chan C. W., Crafton E., Fan H. N., Flook J., Yoshimura K., Skarica M., Brockstedt D., Dubensky T. W., Stins M. F., Lanier L. L., Pardoll D. M., Housseau F., Interferon-producing killer dendritic cells provide a link between innate and adaptive immunity Nature Medicine 2006 12 2 207 213 (Pubitemid 43214747)
49. Jiang Q., Wei H., Tian Z., IFN-producing killer dendritic cells contribute to the inhibitory effect of poly I:C on the progression of murine melanoma Journal of Immunotherapy 2008 31 6 555 562
50. Williams P., Bouchentouf M., Rafei M., Romieu-Mourez R., Hsieh J., Boivin M. N., Yuan S., Forner K. A., Birman E., Galipeau J., A dendritic cell population generated by a fusion of GM-CSF and IL-21 induces tumor-antigen-specific immunity Journal of Immunology 2010 185 12 7358 7366
51. Taylor P. R., Koski G. K., Paustian C. C., Bailey E., Cohen P. A., Moore F. B. G., Zimmerman D. H., Rosenthal K. S., J-LEAPS vaccines initiate murine Th1 responses by activating dendritic cells Vaccine 2010 28 34 5533 5542
52. Taylor P. R., Paustian C. C., Koski G. K., Zimmerman D. H., Rosenthal K. S., Maturation of dendritic cell precursors into IL12-producing DCs by J-LEAPS immunogens Cellular Immunology 2010 262 1 1 5
53. Baban B., Hansen A. M., Chandler P. R., Manlapat A., Bingaman A., Kahler D. J., Munn D. H., Mellor A. L., A minor population of splenic dendritic cells expressing CD19 mediates IDO-dependent T cell suppression via type I IFN signaling following B7 ligation International Immunology 2005 17 7 909 919 (Pubitemid 41417958)
54. Mellor A. L., Baban B., Chandler P. R., Manlapat A., Kahler D. J., Munn D. H., Cutting edge: CpG oligonucleotides induce splenic CD19 + dendritic cells to acquire potent indoleamine 2,3-dioxygenase-dependent T cell regulatory functions via IFN type 1 signaling Journal of Immunology 2005 175 9 5601 5605 (Pubitemid 41508038)
55. Mellor A. L., Chandler P., Baban B., Hansen A. M., Marshall B., Pihkala J., Waldmann H., Cobbold S., Adams E., Munn D. H., Specific subsets of murine dendritic cells acquire potent T cell regulatory functions following CTLA4-mediated induction of indoleamine 2,3 dioxygenase International Immunology 2004 16 10 1391 1401 (Pubitemid 39341552)
56. Mellor A. L., Munn D. H., IDO expression by dendritic cells: tolerance and tryptophan catabolism Nature Reviews Immunology 2004 4 10 762 774 (Pubitemid 39336293)
57. Diebold S. S., Montoya M., Unger H., Alexopoulou L., Roy P., Haswell L. E., Al-Shamkhani A., Flavell R., Borrow P., Reis e Sousa C., Viral infection switches non-plasmacytoid dendritic cells into high interferon producers Nature 2003 424 6946 324 328 (Pubitemid 36899375)
58. Shortman K., Liu Y. J., Mouse and human dendritic cell subtypes Nature Reviews Immunology 2002 2 3 151 161 (Pubitemid 37336516)
59. MacDonald K. P. A., Munster D. J., Clark G. J., Dzionek A., Schmitz J., Hart D. N. J., Characterization of human blood dendritic cell subsets Blood 2002 100 13 4512 4520 (Pubitemid 35429692)
60. Poulin L. F., Salio M., Griessinger E., Anjos-Afonso F., Craciun L., Chen J. L., Keller A. M., Joffre O., Zelenay S., Nye E., Le Moine A., Faure F., Donckier V., Sancho D., Cerundolo V., Bonnet D., Reis E Sousa C., Characterization of human DNGR-1 + BDCA3 + leukocytes as putative equivalents of mouse CD8 + dendritic cells Journal of Experimental Medicine 2010 207 6 1261 1271
61. Bachem A., Gttler S., Hartung E., Ebstein F., Schaefer M., Tannert A., Salama A., Movassaghi K., Opitz C., Mages H. W., Henn V., Kloetzel P. M., Gurka S., Kroczek R. A., Superior antigen cross-presentation and XCR1 expression define human CD11c + CD141 + cells as homologues of mouse CD8 + dendritic cells Journal of Experimental Medicine 2010 207 6 1273 1281
62. Jongbloed S. L., Kassianos A. J., McDonald K. J., Clark G. J., Ju X., Angel C. E., Chen C. J. J., Dunbar P. R., Wadley R. B., Jeet V., Vulink A. J. E., Hart D. N. J., Radford K. J., Human CD141 + (BDCA-3) + dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens Journal of Experimental Medicine 2010 207 6 1247 1260
63. Robbins S. H., Walzer T., Dembélé D., Thibault C., Defays A., Bessou G., Xu H., Vivier E., Sellars M., Pierre P., Sharp F. R., Chan S., Kastner P., Dalod M., Novel insights into the relationships between dendritic cell subsets in human and mouse revealed by genome-wide expression profiling Genome Biology 2008 9 1, article no. R17
64. Klechevsky E., Morita R., Liu M., Cao Y., Coquery S., Thompson-Snipes L., Briere F., Chaussabel D., Zurawski G., Palucka A. K., Reiter Y., Banchereau J., Ueno H., Functional specializations of human epidermal Langerhans cells and CD14 + dermal dendritic cells Immunity 2008 29 3 497 510
65. Van De Ven R., Van Den Hout M. F. C. M., Lindenberg J. J., Sluijter B. J. R., Van Leeuwen P. A. M., Lougheed S. M., Meijer S., Van Den Tol M. P., Scheper R. J., De Gruijl T. D., Characterization of four conventional dendritic cell subsets in human skin-draining lymph nodes in relation to T-cell activation Blood 2011 118 9 2502 2510
66. West E., Morgan R., Scott K., Merrick A., Lubenko A., Pawson D., Selby P., Hatfield P., Prestwich R., Fraser S., Eves D., Anthoney A., Twelves C., Beirne D., Patel P., Odonnell D., Watt S., Waller M., Dietz A., Robinson P., Melcher A., Clinical grade OK432-activated dendritic cells: in vitro characterization and tracking during intralymphatic delivery Journal of Immunotherapy 2009 32 1 66 78
67. Gluckman J. C., Canque B., Chapuis F., Rosenzwajg M., In vitro generation of human dendritic cells and cell therapy Cytokines, Cellular and Molecular Therapy 1997 3 3 187 196 (Pubitemid 27448282)
68. Balan S., Kale V. P., Limaye L. S., A large number of mature and functional dendritic cells can be efficiently generated from umbilical cord blood-derived mononuclear cells by a simple two-step culture method Transfusion 2010 50 11 2413 2423
69. Cahalan M. D., Parker I., Close encounters of the first and second kind: T-DC and T-B interactions in the lymph node Seminars in Immunology 2005 17 6 442 451 (Pubitemid 41654696)
70. Kalinski P., Dendritic cells in immunotherapy of established cancer: Roles of signals 1, 2, 3 and 4 Current Opinion in Investigational Drugs 2009 10 6 526 535
71. Lutz M. B., Schuler G., Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity? Trends in Immunology 2002 23 9 445 449 (Pubitemid 35015188)
72. Liu Y.-J., Kanzler H., Soumelis V., Gilliet M., Dendritic cell lineage, plasticity and cross-regulation Nature Immunology 2001 2 7 585 589 (Pubitemid 32677624)
73. DeNardo D. G., Coussens L. M., Inflammation and breast cancer. Balancing immune response: crosstalk between adaptive and innate immune cells during breast cancer progression Breast Cancer Research 2007 9 4 212
74. Talmadge J. E., Donkor M., Scholar E., Inflammatory cell infiltration of tumors: Jekyll or Hyde Cancer and Metastasis Reviews 2007 26 3-4 373 400 (Pubitemid 350115102)
75. Waldner M., Schimanski C. C., Neurath M. F., Colon cancer and the immune system: the role of tumor invading T cells World Journal of Gastroenterology 2006 12 45 7233 7238 (Pubitemid 44911827)
76. Conejo-Garcia J. R., Benencia F., Courreges M. C., Khang E., Zhang L., Mohamed-Hadley A., Vinocur J. M., Buckanovich R. J., Thompson C. B., Levine B., Coukos G., Letal, a tumor-associated NKG2D immunoreceptor ligand, induces activation and expansion of effector immune cells Cancer Biology and Therapy 2003 2 4 446 451
77. Condamine T., Gabrilovich D. I., Molecular mechanisms regulating myeloid-derived suppressor cell differentiation and function Trends in Immunology 2011 32 1 19 25
78. Teng M. W., Ritchie D. S., Neeson P., Smyth M. J., Biology and clinical observations of regulatory T cells in cancer immunology Current topics in microbiology and immunology 2011 344 61 95
79. Markiewski M. M., DeAngelis R. A., Benencia F., Ricklin-Lichtsteiner S. K., Koutoulaki A., Gerard C., Coukos G., Lambris J. D., Modulation of the antitumor immune response by complement Nature Immunology 2008 9 11 1225 1235
80. Regg C., Leukocytes, inflammation, and angiogenesis in cancer: fatal attractions Journal of Leukocyte Biology 2006 80 4 682 684
81. Peek R. M. Jr., Crabtree J. E., Helicobacter infection and gastric neoplasia Journal of Pathology 2006 208 2 233 248 (Pubitemid 43126116)
82. Szab E., Pska C., Kaposi Novk P., Schaff Z., Kiss A., Similarities and Differences in Hepatitis B and C Virus Induced Hepatocarcinogenesis Pathology and Oncology Research 2004 10 1 5 11 (Pubitemid 38506605)
83. Williams M. D., Sandler A. B., The epidemiology of lung cancer Cancer treatment and research 2001 105 31 52
84. Jura N., Archer H., Bar-Sagi D., Chronic pancreatitis, pancreatic adenocarcinoma and the black box in-between Cell Research 2005 15 1 72 77 (Pubitemid 41653970)
85. Conejo-Garcia J. R., Benencia F., Courreges M. C., Kang E., Mohamed-Hadley A., Buckanovich R. J., Holtz D. O., Jenkins A., Na H., Zhang L., Wagner D. S., Katsaros D., Caroll R., Coukos G., Tumor-infiltrating dendritic cell precursors recruited by a -defensin contribute to vasculogenesis under the influence of Vegf-A Nature Medicine 2004 10 9 950 958 (Pubitemid 39273736)
86. Curiel T. J., Cheng P., Mottram P., Alvarez X., Moons L., Evdemon-Hogan M., Wei S., Zou L., Kryczek I., Hoyle G., Lackner A., Carmeliet P., Zou W., Dendritic cell subsets differentially regulate angiogenesis in human ovarian cancer Cancer Research 2004 64 16 5535 5538 (Pubitemid 39095544)
87. Ribatti D., The paracrine role of tie-2-expressing monocytes in tumor angiogenesis Stem Cells and Development 2009 18 5 703 706
88. Conejo-Garcia J. R., Buckanovich R. J., Benencia F., Courreges M. C., Rubin S. C., Carroll R. G., Coukos G., Vascular leukocytes contribute to tumor vascularization Blood 2005 105 2 679 681 (Pubitemid 40070752)
89. Gough P. J., Gomez I. G., Wille P. T., Raines E. W., Macrophage expression of active MMP-9 induces acute plaque disruption in apoE-deficient mice Journal of Clinical Investigation 2006 116 1 59 69 (Pubitemid 43121791)
90. Baleeiro R. B., Anselmo L. B., Soares F. A., Pinto C. A. L., Ramos O., Gross J. L., Haddad F., Younes R. N., Tomiyoshi M. Y., Bergami-Santos P. C., Barbuto J. A. M., High frequency of immature dendritic cells and altered in situ production of interleukin-4 and tumor necrosis factor- in lung cancer Cancer Immunology, Immunotherapy 2008 57 9 1335 1345
91. Shurin M. R., Shurin G. V., Lokshin A., Yurkovetsky Z. R., Gutkin D. W., Chatta G., Zhong H., Han B., Ferris R. L., Intratumoral cytokines/chemokines/ growth factors and tumor infiltrating dendritic cells: friends or enemies? Cancer and Metastasis Reviews 2006 25 3 333 356 (Pubitemid 44922354)
92. Whiteside T. L., The role of immune cells in the tumor microenvironment Cancer Treatment and Research 2006 130 103 124
93. Mantovani A., Sozzani S., Locati M., Schioppa T., Saccani A., Allavena P., Sica A., Infiltration of tumours by macrophages and dendritic cells: tumour-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes Novartis Foundation Symposium 2004 256 137 145
94. Liu Q., Zhang C., Sun A., Zheng Y., Wang L., Cao X., Tumor-educated CD11bhighIalow regulatory dendritic cells suppress T cell response through arginase I Journal of Immunology 2009 182 10 6207 6216
95. Gabrilovich D. I., Ishida T., Nadaf S., Ohm J. E., Carbone D. P., Antibodies to vascular endothelial growth factor enhance the efficacy of cancer immunotherapy by improving endogenous dendritic cell function Clinical Cancer Research 1999 5 10 2963 2970 (Pubitemid 29493976)
96. Fainaru O., Almog N., Yung C. W., Nakai K., Montoya-Zavala M., Abdollahi A., D'Amato R., Ingber D. E., Tumor growth and angiogenesis are dependent on the presence of immature dendritic cells FASEB Journal 2010 24 5 1411 1418
97. Patan S., Vasculogenesis and angiogenesis as mechanisms of vascular network formation, growth and remodeling Journal of Neuro-Oncology 2000 50 1-2 1 15 (Pubitemid 32166287)
98. Papetti M., Herman I. M., Mechanisms of normal and tumor-derived angiogenesis American Journal of Physiology 2002 282 5 C947 C970
99. Djonov V., Baum O., Burri P. H., Vascular remodeling by intussusceptive angiogenesis Cell and Tissue Research 2003 314 1 107 117 (Pubitemid 37409917)
100. Bailey A. S., Fleming W. H., Converging roads: evidence for an adult hemangioblast Experimental Hematology 2003 31 11 987 993 (Pubitemid 37329740)
101. Fernandez Pujol B., Lucibello F. C., Gehling U. M., Lindemann K., Weidner N., Zuzarte M. L., Adamkiewicz J., Elssser H. P., Mller R., Havemann K., Endothelial-like cells derived from human CD14 positive monocytes Differentiation 2000 65 5 287 300 (Pubitemid 30406634)
102. Schmeisser A., Garlichs C. D., Zhang H., Eskafi S., Graffy C., Ludwig J., Strasser R. H., Daniel W. G., Monocytes coexpress endothelial and macrophagocytic lineage markers and form cord-like structures in Matrigel under angiogenic conditions Cardiovascular Research 2001 49 3 671 680 (Pubitemid 32146430)
103. Bellik L., Musilli C., Vinci M. C., Ledda F., Parenti A., Human mature endothelial cells modulate peripheral blood mononuclear cell differentiation toward an endothelial phenotype Experimental Cell Research 2008 314 16 2965 2974
104. Rehman J., Li J., Orschell C. M., March K. L., Peripheral blood "endothelial progenitor cells" are derived from monocyte/macrophages and secrete angiogenic growth factors Circulation 2003 107 8 1164 1169 (Pubitemid 36297209)
105. Lewis C. E., De Palma M., Naldini L., Tie2-expressing monocytes and tumor angiogenesis: regulation by hypoxia and angiopoietin-2 Cancer Research 2007 67 18 8429 8432 (Pubitemid 47437413)
106. Kuwana M., Okazaki Y., Kodama H., Satoh T., Kawakami Y., Ikeda Y., Endothelial differentiation potential of human monocyte-derived multipotential cells Stem Cells 2006 24 12 2733 2743 (Pubitemid 46053011)
107. Chen H., Campbell R. A., Chang Y., Li M., Wang C. S., Li J., Sanchez E., Share M., Steinberg J., Berenson A., Shalitin D., Zeng Z., Gui D., Perez-Pinera P., Berenson R. J., Said J., Bonavida B., Deuel T. F., Berenson J. R., Pleiotrophin produced by multiple myeloma induces transdifferentiation of monocytes into vascular endothelial cells: a novel mechanism of tumor-induced vasculogenesis Blood 2009 113 9 1992 2002
108. Li B., Pozzi A., Young P. P., TNF accelerates monocyte to endothelial transdifferentiation in tumors by the induction of integrin 5 expression and adhesion to fibronectin Molecular Cancer Research 2011 9 6 702 711
109. Pujol B. F., Lucibello F. C., Zuzarte M., Ltjens P., Mller R., Havemann K., Dendritic cells derived from peripheral monocytes express endothelial markers and in the presence of angiogenic growth factors differentiate into endothelial-like cells European Journal of Cell Biology 2001 80 1 99 110 (Pubitemid 32098116)
110. Gottfried E., Kreutz M., Haffner S., Holler E., Iacobelli M., Andreesen R., Eissner G., Differentiation of human tumour-associated dendritic cells into endothelial-like cells: an alternative pathway of tumour angiogenesis Scandinavian Journal of Immunology 2007 65 4 329 335 (Pubitemid 46481100)
111. Lu J., Liu K., Zhao J., Zhao J., Ma J., Yang H., Huang Y., Qin Z., Bai R., Jiang L., Lv F., Li P., Yan W., Zhao M., Dong Z., VEGF-A not Ang2 mediates endothelial-like differentiation of immature DCs by ERK1/2 signaling in the microenvironment of human colon adenocarcinoma International Journal of Oncology 2011 38 6 1579 1588
112. Lu J., Zhao J., Liu K., Zhao J., Yang H., Huang Y., Qin Z., Bai R., Li P., Ma J., Yan W., Zhao M., Dong Z., MAPK/ERK1/2 signaling mediates endothelial-like differentiation of immature DCs in the microenvironment of esophageal squamous cell carcinoma Cellular and Molecular Life Sciences 2010 67 12 2091 2106
113. Huarte E., Cubillos-Ruiz J. R., Nesbeth Y. C., Scarlett U. K., Martinez D. G., Buckanovich R. J., Benencia F., Stan R. V., Keler T., Sarobe P., Sentman C. L., Conejo-Garcia J. R., Depletion of dendritic cells delays ovarian cancer progression by boosting antitumor immunity Cancer Research 2008 68 18 7684 7691
114. Tzeng T. C., Chyou S., Tian S., Webster B., Carpenter A. C., Guaiquil V. H., Lu T. T., CD11chi dendritic cells regulate the re-establishment of vascular quiescence and stabilization after immune stimulation of lymph nodes Journal of Immunology 2010 184 8 4247 4257
115. Sozzani S., Rusnati M., Riboldi E., Mitola S., Presta M., Dendritic cell-endothelial cell cross-talk in angiogenesis Trends in Immunology 2007 28 9 385 392 (Pubitemid 47385377)
116. Sprague L., Muccioli M., Pate M., Meles E., McGinty J., Nandigam H., Venkatesh A. K., Gu M., Mansfield K., Rutowski A., Omosebi O., Courreges M. C., Benencia F., The interplay between surfaces and soluble factors define the immunologic and angiogenic properties of myeloid dendritic cells BMC Immunology 2011 12, article 35
117. Coukos G., Benencia F., Buckanovich R. J., Conejo-Garcia J. R., The role of dendritic cell precursors in tumour vasculogenesis British Journal of Cancer 2005 92 7 1182 1187 (Pubitemid 40604389)
118. Bak S. P., Walters J. J., Takeya M., Conejo-Garcia J. R., Berwin B. L., Scavenger receptor-A-targeted leukocyte depletion inhibits peritoneal ovarian tumor progression Cancer Research 2007 67 10 4783 4789 (Pubitemid 46910186)
119. Fainaru O., Adini A., Benny O., Adini I., Short S., Bazinet L., Nakai K., Pravda E., Hornstein M. D., D'Amato R. J., Folkman J., Dendritic cells support angiogenesis and promote lesion growth in a murine model of endometriosis FASEB Journal 2008 22 2 522 529 (Pubitemid 351225588)
120. Ridgway D., The first 1000 dendritic cell vaccinees Cancer Investigation 2003 21 6 873 886 (Pubitemid 38055985)
121. Gilboa E., DC-based cancer vaccines Journal of Clinical Investigation 2007 117 5 1195 1203 (Pubitemid 46718404)
122. Yamaguchi S., Tatsumi T., Takehara T., Sasakawa A., Hikita H., Kohga K., Uemura A., Sakamori R., Ohkawa K., Hayashi N., Dendritic cell-based vaccines suppress metastatic liver tumor via activation of local innate and acquired immunity Cancer Immunology, Immunotherapy 2008 57 12 1861 1869
123. Hatfield P., Merrick A. E., West E., O'Donnell D., Selby P., Vile R., Melcher A. A., Optimization of dendritic cell loading with tumor cell lysates for cancer immunotherapy Journal of Immunotherapy 2008 31 7 620 632
124. Courrges M. C., Benencia F., Conejo-Garca J. R., Zhang L., Coukos G., Preparation of apoptotic tumor cells with replication-incompetent HSV augments the efficacy of dendritic cell vaccines Cancer Gene Therapy 2006 13 2 182 193 (Pubitemid 43113419)
125. Shirota H., Klinman D. M., CpG-conjugated apoptotic tumor cells elicit potent tumor-specific immunity Cancer Immunology, Immunotherapy 2011 60 5 659 669
126. Pilon-Thomas S., Verhaegen M., Kuhn L., Riker A., Mulé J. J., Induction of anti-tumor immunity by vaccination with dendritic cells pulsed with anti-CD44 IgG opsonized tumor cells Cancer Immunology, Immunotherapy 2006 55 10 1238 1246 (Pubitemid 43992050)
127. Ma W., Smith T., Bogin V., Zhang Y., Ozkan C., Ozkan M., Hayden M., Schroter S., Carrier E., Messmer D., Kumar V., Minev B., Enhanced presentation of MHC class Ia, Ib and class II-restricted peptides encapsulated in biodegradable nanoparticles: a promising strategy for tumor immunotherapy Journal of Translational Medicine 2011 9, article 34
128. Xu F., Ye Y.-J., Liu W., Kong M., He Y., Wang S., Dendritic cell/tumor hybrids enhances therapeutic efficacy against colorectal cancer liver metastasis in SCID mice Scandinavian Journal of Gastroenterology 2010 45 6 707 713
129. Benencia F., Courrges M. C., Coukos G., Whole tumor antigen vaccination using dendritic cells: comparison of RNA electroporation and pulsing with UV-irradiated tumor cells Journal of Translational Medicine 2008 6, article 21
130. Yang H. G., Hu B. L., Xiao L., Wang P., Dendritic cell-directed lentivector vaccine induces antigen-specific immune responses against murine melanoma Cancer Gene Therapy 2011 18 5 370 380
131. Liu Y., Butterfield L. H., Fu X., Song Z., Zhang X., Lu C., Ding G., Wu M., Lentivirally engineered dendritic cells activate AFP-specific T cells which inhibit hepatocellular carcinoma growth in vitro and in vivo International Journal of Oncology 2011 39 1 245 253
132. Felizardo T. C., Wang J. C. M., McGray R. A. J., Evelegh C., Spaner D. E., Fowler D. H., Bramson J. L., Medin J. A., Differential immune responses mediated by adenovirus-and lentivirus-transduced DCs in a HER-2/neu overexpressing tumor model Gene Therapy 2011 18 10 986 995
133. Cui Y., Kelleher E., Straley E., Fuchs E., Gorski K., Levitsky H., Borrello I., Civin C. I., Schoenberger S. P., Cheng L., Pardoll D. M., Whartenby K. A., Immunotherapy of established tumors using bone marrow transplantation with antigen gene-modified hematopoietic stem cells Nature Medicine 2003 9 7 952 958 (Pubitemid 36889940)
134. Kacani L., Wurm M., Schwentner I., Andrle J., Schennach H., Sprinzl G.
135. Brusa D., Garetto S., Chiorino G., Scatolini M., Migliore E., Camussi G., Matera L., Post-apoptotic tumors are more palatable to dendritic cells and enhance their antigen cross-presentation activity Vaccine 2008 26 50 6422 6432
136. Bonehill A., Heirman C., Tuyaerts S., Michiels A., Breckpot K., Brasseur F., Zhang Y., Van Der Bruggen P., Thielemans K., Messenger RNA-electroporated dendritic cells presenting MAGE-A3 simultaneously in HLA class I and class II molecules Journal of Immunology 2004 172 11 6649 6657 (Pubitemid 38669100)
137. Sun L., Kong B., Sheng X., Sheu J. J.-C., Shih I.-M., Dendritic cells transduced with Rsf-1/HBXAP gene generate specific cytotoxic T lymphocytes against ovarian cancer in vitro Biochemical and Biophysical Research Communications 2010 394 3 633 638
138. Zhang Y., Ma B., Zhou Y., Zhang M., Qiu X., Sui Y., Zhang X., Ma B., Fan Q., Dendritic cells fused with allogeneic breast cancer cell line induce tumor antigen-specific CTL responses against autologous breast cancer cells Breast Cancer Research and Treatment 2007 105 3 277 286 (Pubitemid 47596446)
139. Lotem M., Zhao Y., Riley J., Hwu P., Morgan R. A., Rosenberg S. A., Parkhurst M. R., Presentation of tumor antigens by dendritic cells genetically modified with viral and nonviral vectors Journal of Immunotherapy 2006 29 6 616 627 (Pubitemid 44674045)
140. Linette G. P., Shankara S., Longerich S., Yang S., Doll R., Nicolette C., Preffer F. I., Roberts B. L., Haluska F. G., In vitro priming with adenovirus/gp100 antigen-transduced dendritic cells reveals the epitope specificity of HLA-A0201-restricted CD8 + T cells in patients with melanoma Journal of Immunology 2000 164 6 3402 3412 (Pubitemid 30149007)
141. Dietz A. B., Vuk-Pavlovi S., High efficiency adenovirus-mediated gene transfer to human dendritic cells Blood 1998 91 2 392 398 (Pubitemid 28053360)
142. Miyazawa M., Iwahashi M., Ojima T., Katsuda M., Nakamura M., Nakamori M., Ueda K., Naka T., Hayata K., Iida T., Yamaue H., Dendritic cells adenovirally-transduced with full-length mesothelin cDNA elicit mesothelin-specific cytotoxicity against pancreatic cancer cell lines in vitro Cancer Letters 2011 305 1 32 39
143. Bonini C., Lee S. P., Riddell S. R., Greenberg P. D., Targeting antigen in mature dendritic cells for simultaneous stimulation of CD4 + and CD8 + T cells Journal of Immunology 2001 166 8 5250 5257 (Pubitemid 32280742)
144. Cui Y., Golob J., Kelleher E., Ye Z., Pardoll D., Cheng L., Targeting transgene expression to antigen-presenting cells derived from lentivirus-transduced engrafting human hematopoietic stem/progenitor cells Blood 2002 99 2 399 408 (Pubitemid 34533073)
145. Lizée G., Gonzales M. I., Topalian S. L., Lentivirus vector-mediated expression of tumor-associated epitopes by human antigen presenting cells Human Gene Therapy 2004 15 4 393 404 (Pubitemid 38469781)
146. Wierecky J., Mller M. R., Wirths S., Halder-Oehler E., Drfel D., Schmidt S. M., Hntschel M., Brugger W., Schrder S., Horger M. S., Kanz L., Brossart P., Immunologic and clinical responses after vaccinations with peptide-pulsed dendritic cells in metastatic renal cancer patients Cancer Research 2006 66 11 5910 5918 (Pubitemid 43927146)
147. Ovali E., Dikmen T., Sonmez M., Yilmaz M., Unal A., Dalbasti T., Kuzeyli K., Erturk M., Omay S. B., Active immunotherapy for cancer patients using tumor lysate pulsed dendritic cell vaccine: a safety study Journal of Experimental and Clinical Cancer Research 2007 26 2 209 214 (Pubitemid 47025284)
148. Suso E. M. I., Dueland S., Rasmussen A.-M., Vetrhus T., Aamdal S., Kvalheim G., Gaudernack G., HTERT mRNA dendritic cell vaccination: complete response in a pancreatic cancer patient associated with response against several hTERT epitopes Cancer Immunology, Immunotherapy 2011 60 6 809 818
149. Van Driessche A., Van De Velde A. L. R., Nijs G., Braeckman T., Stein B., De Vries J. M., Berneman Z. N., Van Tendeloo V. F. I., Clinical-grade manufacturing of autologous mature mRNA-electroporated dendritic cells and safety testing in acute myeloid leukemia patients in a phase i dose-escalation clinical trial Cytotherapy 2009 11 5 653 668
150. Akasaki Y., Kikuchi T., Irie M., Yamamoto Y., Arai T., Tanaka T., Joki T., Abe T., Cotransfection of poly(I: C) and siRNA of IL-10 into fusions of dendritic and glioma cells enhances antitumor T helper type 1 induction in patients with glioma Journal of Immunotherapy 2011 34 2 121 128
151. Rosenblatt J., Vasir B., Uhl L., Blotta S., MacNamara C., Somaiya P., Wu Z., Joyce R., Levine J. D., Dombagoda D., Yuan Y. E., Francoeur K., Fitzgerald D., Richardson P., Weller E., Anderson K., Kufe D., Munshi N., Avigan D., Vaccination with dendritic cell/tumor fusion cells results in cellular and humoral antitumor immune responses in patients with multiple myeloma Blood 2011 117 2 393 402
152. Han T. H., Jin P., Ren J., Slezak S., Marincola F. M., Stroncek D. F., Evaluation of 3 clinical dendritic cell maturation protocols containing lipopolysaccharide and interferon- Journal of Immunotherapy 2009 32 4 399 407
153. Banerjee D. K., Dhodapkar M. V., Matayeva E., Steinman R. M., Dhodapkar K. M., Expansion of FOXP3high regulatory T cells by human dendritic cells (DCs) in vitro and after injection of cytokine-matured DCs in myeloma patients Blood 2006 108 8 2655 2661
154. Muthuswamy R., Urban J., Lee J. J., Reinhart T. A., Bartlett D., Kalinski P., Ability of mature dendritic cells to interact with regulatory T cells is imprinted during maturation Cancer Research 2008 68 14 5972 5978
155. Mailliard R. B., Wankowicz-Kalinska A., Cai Q., Wesa A., Hilkens C. M., Kapsenberg M. L., Kirkwood J. M., Storkus W. J., Kalinski P., -type-1 polarized dendritic cells: a novel immunization tool with optimized CTL-inducing activity Cancer Research 2004 64 17 5934 5937 (Pubitemid 39129387)
156. Gustafsson K., Junevik K., Werlenius O., Holmgren S., Karlsson-Parra A., Andersson P.-O., Tumour-loaded -type 1-polarized Dendritic cells from patients with chronic lymphocytic leukaemia produce a superior NK -, NKT - and CD8 + T cell-attracting chemokine profile Scandinavian Journal of Immunology 2011 74 3 318 326
157. Van Den Ancker W., Van Luijn M. M., Ruben J. M., Westers T. M., Bontkes H. J., Ossenkoppele G. J., De Gruijl T. D., Van De Loosdrecht A. A., Targeting Toll-like receptor 7/8 enhances uptake of apoptotic leukemic cells by monocyte-derived dendritic cells but interferes with subsequent cytokine-induced maturation Cancer Immunology, Immunotherapy 2011 60 1 37 47
158. Wieckowski E., Chatta G. S., Mailliard R. M., Gooding W., Palucka K., Banchereau J., Kalinski P., Type-1 polarized dendritic cells loaded with apoptotic prostate cancer cells are potent inducers of CD8 + T cells against prostate cancer cells and defined prostate cancer-specific epitopes Prostate 2011 71 2 125 133
159. Gustafsson K., Ingelsten M., Bergqvist L., Nystrm J., Andersson B., Karlsson-Parra A., Recruitment and activation of natural killer cells in vitro by a human dendritic cell vaccine Cancer Research 2008 68 14 5965 5971
160. Trepiakas R., Pedersen A. E., Met., Hansen M. H., Berntsen A., Svane I. M., Comparison of -Type-1 polarizing and standard dendritic cell cytokine cocktail for maturation of therapeutic monocyte-derived dendritic cell preparations from cancer patients Vaccine 2008 26 23 2824 2832
161. Barth R. J. Jr., Fisher D. A., Wallace P. K., Channon J. Y., Noelle R. J., Gui J., Ernstoff M. S., A randomized trial of ex vivo CD40L activation of a dendritic cell vaccine in colorectal cancer patients: tumor-specific immune responses are associated with improved survival Clinical Cancer Research 2010 16 22 5548 5556
162. Cranmer L. D., Trevor K. T., Hersh E. M., Clinical applications of dendritic cell vaccination in the treatment of cancer Cancer Immunology, Immunotherapy 2004 53 4 275 306 (Pubitemid 38392306)
163. Lesterhuis W. J., de Vries I. J.M., Adema G. J., Punt C. J.A., Dendritic cell-based vaccines in cancer immunotherapy: an update on clinical and immunological results Annals of Oncology 2004 15 supplement 4 145 151
164. Carballido E., Fishman M., Sipuleucel-T: prototype for development of anti-tumor vaccines Current Oncology Reports 2011 13 2 112 119
165. Hall S. J., Klotz L., Pantuck A. J., George D. J., Whitmore J. B., Frohlich M. W., Sims R. B., Integrated safety data from 4 randomized, double-blind, controlled trials of autologous cellular immunotherapy with sipuleucel-T in patients with prostate cancer Journal of Urology 2011 186 3 877 881
166. Kantoff P. W., Higano C. S., Shore N. D., Berger E. R., Small E. J., Penson D. F., Redfern C. H., Ferrari A. C., Dreicer R., Sims R. B., Xu Y., Frohlich M. W., Schellhammer P. F., Sipuleucel-T immunotherapy for castration-resistant prostate cancer New England Journal of Medicine 2010 363 5 411 422
167. Chu C. S., Boyer J., Schullery D. S., Gimotty P. A., Gamerman V., Bender J., Levine B. L., Coukos G., Rubin S. C., Morgan M. A., Vonderheide R. H., June C. H., Phase I/II randomized trial of dendritic cell vaccination with or without cyclophosphamide for consolidation therapy of advanced ovarian cancer in first or second remission. Cancer Immunology, Immunotherapy. In press
168. Feijo E., Alfaro C., Mazzolini G., Serra P., Peuelas I., Arina A., Huarte E., Tirapu I., Palencia B., Murillo O., Ruiz J., Sangro B., Richter J. A., Prieto J., Melero I., Dendritic cells delivered inside human carcinomas are sequestered by interleukin-8 International Journal of Cancer 2005 116 2 275 281 (Pubitemid 40967265)
169. McAllister S. S., Gifford A. M., Greiner A. L., Kelleher S. P., Saelzler M. P., Ince T. A., Reinhardt F., Harris L. N., Hylander B. L., Repasky E. A., Weinberg R. A., Systemic endocrine instigation of indolent tumor growth requires osteopontin Cell 2008 133 6 994 1005 (Pubitemid 351787747)
170. Gabrilovich D. I., Chen H. L., Girgis K. R., Cunningham H. T., Meny G. M., Nadaf S., Kavanaugh D., Carbone D. P., Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells Nature Medicine 1996 2 10 1096 1103 (Pubitemid 26338628)
171. Maes W., Rosas G. G., Verbinnen B., Boon L., De Vleeschouwer S., Ceuppens J. L., Van Gool S. W., DC vaccination with anti-CD25 treatment leads to long-term immunity against experimental glioma Neuro-Oncology 2009 11 5 529 542
172. Prasad S. J., Farrand K. J., Matthews S. A., Chang J. H., McHugh R. S., Ronchese F., Dendritic cells loaded with stressed tumor cells elicit long-lasting protective tumor immunity in mice depleted of CD4 + CD25 + regulatory T cells Journal of Immunology 2005 174 1 90 98 (Pubitemid 40007395)
173. Delluc S., Hachem P., Rusakiewicz S., Gaston A., Marchiol-Fournigault C., Tourneur L., Babchia N., Fradelizi D., Regnault A., Sang K. H., Chiocchia G., Buzyn A., Dramatic efficacy improvement of a DC-based vaccine against AML by CD25 T cell depletion allowing the induction of a long-lasting T cell response Cancer Immunology, Immunotherapy 2009 58 10 1669 1677
174. Morse M. A., Hobeika A. C., Osada T., Serra D., Niedzwiecki D., Kim Lyerly H., Clay T. M., Depletion of human regulatory T cells specifically enhances antigen-specific immune responses to cancer vaccines Blood 2008 112 3 610 618
175. Dannull J., Nair S., Su Z., Boczkowski D., DeBeck C., Yang B., Gilboa E., Vieweg J., Enhancing the immunostimulatory function of dendritic cells by transfection with mRNA encoding OX40 ligand Blood 2005 105 8 3206 3213
176. Jacobs J. F. M., Punt C. J. A., Lesterhuis W. J., Sutmuller R. P. M., Brouwer H. M. L. H., Scharenborg N. M., Klasen I. S., Hilbrands L. B., Figdor C. G., De Vries I. J. M., Adema G. J., Dendritic cell vaccination in combination with anti-CD25 monoclonal antibody treatment: a phase I/II study in metastatic melanoma patients Clinical Cancer Research 2010 16 20 5067 5078
177. Saha A., Chatterjee S. K., Combination of CTL-associated antigen-4 blockade and depletion of CD25 + regulatory T cells enhance tumour immunity of dendritic cell-based vaccine in a mouse model of colon cancer Scandinavian Journal of Immunology 2010 71 2 70 82
178. Gadri Z., Kukulansky T., Bar-Or E., Haimovich J., Hollander N., Synergistic effect of dendritic cell vaccination and anti-CD20 antibody treatment in the therapy of murine lymphoma Journal of Immunotherapy 2009 32 4 333 340
179. Driessens G., Nuttin L., Gras A., Maetens J., Mievis S., Schoore M., Velu T., Tenenbaum L., Préat V., Bruyns C., Development of a successful antitumor therapeutic model combining in vivo dendritic cell vaccination with tumor irradiation and intratumoral GM-CSF delivery Cancer Immunology, Immunotherapy 2011 60 2 273 281
180. He Q., Li J., Yin W., Song Z., Zhang Z., Yi T., Tang J., Wu D., Lu Y., Wang Z., Liu D., Zhang X., Hu Z., Gao J., Low-dose paclitaxel enhances the anti-tumor efficacy of GM-CSF surface-modified whole-tumor-cell vaccine in mouse model of prostate cancer Cancer Immunology, Immunotherapy 2011 60 5 715 730
181. Zhang S.-N., Choi I.-K., Huang J.-H., Yoo J.-Y., Choi K.-J., Yun C.-O., Optimizing DC vaccination by combination with oncolytic adenovirus coexpressing IL-12 and GM-CSF Molecular Therapy 2011 19 8 1558 1568
182. Almand B., Resser J. R., Lindman B., Nadaf S., Clark J. I., Kwon E. D., Carbone D. P., Gabrilovich D. I., Clinical significance of defective dendritic cell differentiation in cancer Clinical Cancer Research 2000 6 5 1755 1766 (Pubitemid 30305068)
183. Vicari A. P., Chiodoni C., Vaure C., At-Yahia S., Dercamp C., Matsos F., Reynard O., Taverne C., Merle P., Colombo M. P., O'Garra A., Trinchieri G., Caux C., Reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin 10 receptor antibody Journal of Experimental Medicine 2002 196 4 541 549
184. Vermi W., Bonecchi R., Facchetti F., Bianchi D., Sozzani S., Festa S., Berenzi A., Cella M., Colonna M., Recruitment of immature plasmacytoid dendritic cells (plasmacytoid monocytes) and myeloid dendritic cells in primary cutaneous melanomas Journal of Pathology 2003 200 2 255 268 (Pubitemid 36748035)
185. Ugolini C., Basolo F., Proietti A., Vitti P., Elisei R., Miccoli P., Toniolo A., Lymphocyte and immature dendritic cell infiltrates in differentiated, poorly differentiated, and undifferentiated thyroid carcinoma Thyroid 2007 17 5 389 393 (Pubitemid 46878841)
186. Buckanovich R. J., Facciabene A., Kim S., Benencia F., Sasaroli D., Balint K., Katsaros D., O'Brien-Jenkins A., Gimotty P. A., Coukos G., Endothelin B receptor mediates the endothelial barrier to T cell homing to tumors and disables immune therapy Nature Medicine 2008 14 1 28 36
187. Wang B., Kuroiwa J. M. Y., He L. Z., Charalambous A., Keler T., Steinman R. M., The human cancer antigen mesothelin is more efficiently presented to the mouse immune system when targeted to the DEC-205/CD205 receptor on dendritic cells Annals of the New York Academy of Sciences 2009 1174 6 17
188. Wei H., Wang S., Zhang D., Hou S., Qian W., Li B., Guo H., Kou G., He J., Wang H., Guo Y., Targeted delivery of tumor antigens to activated dendritic cells via CD11c molecules induces potent antitumor immunity in mice Clinical Cancer Research 2009 15 14 4612 4621
189. Faham A., Altin J. G., Antigen-containing liposomes engrafted with flagellin-related peptides are effective vaccines that can induce potent antitumor immunity and immunotherapeutic effect Journal of Immunology 2010 185 3 1744 1754
190. Cruz L. J., Tacken P. J., Fokkink R., Joosten B., Stuart M. C., Albericio F., Torensma R., Figdor C. G., Targeted PLGA nano- but not microparticles specifically deliver antigen to human dendritic cells via DC-SIGN in vitro Journal of Controlled Release 2010 144 2 118 126
191. Ni J., Nolte B., Arnold A., Fournier P., Schirrmacher V., Targeting anti-tumor DNA vaccines to dendritic cells via a short CD11c promoter sequence Vaccine 2009 27 40 5480 5487
192. Hu B., Dai B., Wang P., Vaccines delivered by integration-deficient lentiviral vectors targeting dendritic cells induces strong antigen-specific immunity Vaccine 2010 28 41 6675 6683
193. Cubillos-Ruiz J. R., Engle X., Scarlett U. K., Martinez D., Barber A., Elgueta R., Wang L., Nesbeth Y., Durant Y., Gewirtz A. T., Sentman C. L., Kedl R., Conejo-Garcia J. R., Polyethylenimine-based siRNA nanocomplexes reprogram tumor-associated dendritic cells via TLR5 to elicit therapeutic antitumor immunity Journal of Clinical Investigation 2009 119 8 2231 2244
194. Benencia F., Courrges M. C., Fraser N. W., Coukos G., Herpes virus oncolytic therapy reverses tumor immune dysfunction and facilitates tumor antigen presentation Cancer Biology and Therapy 2008 7 8 1194 1205