Dendritic cell lineage, plasticity and cross-regulation

Nature Immunology

Volumn 2, Issue 7, 2001, Pages 585-589

  Liu Yong Jun, ^a   Kanzler, H ^a   Soumelis, V ^a   Gilliet, M ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERFERON;

ANTIGEN PRESENTING CELL; BONE MARROW CELL; CELL FUNCTION; CELL LINEAGE; CELLULAR IMMUNITY; DENDRITIC CELL; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOREGULATION; LYMPHOID CELL; MICROORGANISM; NEGATIVE FEEDBACK; PATHOGENICITY; PLASTICITY; PRIMARY IMMUNE RESPONSE; PRIORITY JOURNAL; REGULATORY MECHANISM; REVIEW; T LYMPHOCYTE ACTIVATION; TH1 CELL; TH2 CELL;

ANIMALS; ANTIGENS, DIFFERENTIATION, B-LYMPHOCYTE; CELL LINEAGE; CROSS REACTIONS; CYTOKINES; DENDRITIC CELLS; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; INTERFERON TYPE I; INTERFERON TYPE II; LYMPHOID TISSUE; TH1 CELLS; TH2 CELLS;

EID: 0034919938     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/89726     Document Type: Review

References (87)

1. Dendritic cells and the control of immunity
2. Origin, maturation and antigen presenting function of dendritic cells
3. The role of dendritic cells in the induction and regulation of immunity to microbial infection
4. H2 development
5. + T cells
6. Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation
7. High level IL-12 production by murine dendritic cells: Upregulation via MHC class II and CD40 molecules and downregulation by IL-4 and IL-10
8. In vivo microbial stimulation induces rapid CD40 ligand-independent production of interleukin 12 by dendritic cells and their redistribution to T cell areas
9. Reciprocal control of T helper cell and dendritic cell differentiation
10. Distinct dendritic cell subsets differentially regulate the class of immune response in vivo
11. + and CD8α-subclasses of dendritic cells direct the development of distinct T helper cells in vivo
12. Differential regulation of human blood dendritic cell subsets by IFNs
13. Granulocyte-colony stimulating factor mobilizes T helper 2-inducing dendritic cells
14. T-cell priming by type-1 and type-2 polarized dendritic cells: The concept of a third signal
15. Induction of interleukin 10-producing, non-proliferating CD4(+)T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells
16. Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cells
17. + T suppressor cells by DC2
18. CpG DNA: A potent signal for growth, activation, and maturation of human dendritic cells
19. Bacterial DNA and CpG-containing oligodeoxynucleotides activate cutaneous dendritic cells and induce IL-12 production: Implications for the augmentation of Th1 responses
20. Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells
21. Activation of cutaneous dendritic cells by CpG-containing oligodeoxynucleotides: A role for dendritic cells in the augmentation of Th1 responses by immunostimulatory DNA
22. Polyriboinosinic polyribocytidylic acid (poly(I:C)) induces stable maturation of functionally active human dendritic cells
23. TGF-β1 alters APC preference, polarizing islet antigen responses toward a Th2 phenotype
24. Critical contribution of OX40 ligand to T helper cell type 2 differentiation in experimental leishmaniasis
25. + T cells into high IL-4-producing effectors
26. Natural interferon α/β-producing cells link innate and adaptive immunity
27. Hl polarization
28. Human monocyte-derived dendritic cells induce naive T cell differentiation into T helper cell type 2 (Th2) or Th1/Th2 effectors. Role of stimulator/responder ratio
29. Final maturation of dendritic cells is associated with impaired responsiveness to IFN-γ and bacterial IL-12 inducers: Decreased ability of mature dendritic cells to produce IL-12 during the interaction with Th cells
30. Paralysis of dendritic cell IL-12 production by microbial products prevents infection-induced immunopathology
31. H2 and nonpolarized T cells
32. Dendritic cells discriminate between yeasts and hyphae of the fungus Candida albicans. Implications for initiation of T helper cell immunity in vitro and in vivo
33. Modulating the immune response with dendritic cells and their growth factors
34. Signaling by toll-like receptor 2 and 4 agonists results in differential gene expression in murine macrophages
35. A filarial nematode-secreted product signals dendritic cells to acquire a phenotype that drive development of Th2 cells
36. Freshly isolated Peyer's patch, but not spleen, dendritic cells produce interleukin 10 and induce the differentiation of T helper type 2 cells
37. Resting respiratory tract dendritic cells preferentially stimulate T helper cell type 2 (Th2) responses and require obligatory cytokine signals for induction of Th1 immunity
38. Effects of liver-derived dendritic cell progenitors on Th1- and Th2-like cytokine responses In vitro and In vivo
39. Thymic dendritic cells and T cells develop simultaneously in the thymus from a common precursor population
40. + pro-B cells can give rise to dendritic cells in vitro
41. Dendritic cell subtypes in mouse lymphoid organs: Cross-correlation of surface markers, changes with incubation, and differences among thymus, spleen, and lymph nodes
42. Developmental pathways of dendritic cells in vivo: Distinct function, phenotype, and localization of dendritic cell subsets in FLT3 ligand-treated mice
43. The development, maturation, and turnover rate of mouse spleen dendritic cell populations
44. Burnet oration: Dendritic cells: Multiple subtypes, multiple origins, multiple functions
45. Development of CD8α-positive dendritic cells from a common myeloid progenitor
46. Generation of murine dendritic cells from flt3-ligand-supplemented bone marrow cultures
47. T-associated plasma-cells
48. Plasmacytoid T cells. Immunohistochemical evidence for their monocyte/macrophage origin
49. The enigmatic plasmacytoid T cells develop into dendritic cells with interleukin (IL)-3 and CD40-ligand
50. Dendritic cell ontogeny: A human dendritic cell lineage of myeloid origin
51. Human blood contains two subsets of dendritic cells, one immunologically mature and the other immature
52. +lin-peripheral blood cells with dendritic precursor characteristics
53. + peripheral blood dendritic cells are differentially regulated by cytokines
54. Identification of cord blood dendritic cells as an immature CD11c population
55. Expression of pTα mRNA in a committed dendritic cell precursor in the human thymus
56. Distinct cytokine profiles of neonatal natural killer T cells after expansion with subsets of dendritic cells
57. Id2 and Id3 inhibit development of CD34(+) stem cells into predendritic cell (pre-DC)2 but not into pre-DCI. Evidence for a lymphoid origin of pre-DC2
58. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor α
59. Proliferating dendritic cell progenitors in human blood
60. α24T cells: Lymphocytes of innate immunity
61. Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products
62. Cutting edge: Inflammatory signaling by Borrelia burgdorferi lipoproteins is mediated by toll-like receptor 2
63. Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2
64. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
65. A Toll-like receptor recognizes bacterial DNA
66. BDCA-2, BDCA-3, and BDCA-4: Three markers for distinct subsets of dendritic cells in human peripheral blood
67. BDCA-2, a novel plasmacytoid dendritic cell-specific transmembrane protein: Molecular cloning and functional characterization. Keystone Symposium: Dendritic cell: Interfaces with immunobiology and medicine
68. Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon
69. The nature of the principal type 1 interferon-producing cells in human blood
70. Human natural interferon-α-producing cells
71. Isolation and characterization of murine plasmacytoid dendritic cells
72. The IFN-α producing cells in mice are immature CD11 clow CD8a-CD11b- dendritic cells. Keystone Symposium: Dendritic cell: Interfaces with immunobiology and medicine
73. Selective loss of type 1 interferon-induced STAT4 activation caused by a minisatellite insertion in mouse STAT2
74. The role of Stat4 in species-specific regulation of Th cell development by type 1 IFNs
75. Two roads diverged: Interferon α/β- and interleukin 12-mediated pathways in promoting T cell interferon γ responses during viral infection
76. Interferon-α/β inhibition of interleukin 12 and interferon-γ production in vitro and endogenously during viral infection
77. Type 1 IFNs inhibit human dendritic cell IL-12 production and Th1 cell development
78. Interferon-α and dendritic cells: Novel therapeutic targets in systemic lupus erythematosus
79. + T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
80. + T cells: IL-4 and IFN-γ have opposing effects, while TGF-β positively regulates its own production
81. IL-4 is a mediator of IL-12p70 induction by human Th2 cells: Reversal of polarized Th2 phenotype dendritic cells
82. Interleukin (IL)-4 is a major regulatory cytokine governing bioactive IL-12 production by mouse and human dendritic cells
83. Recombinant IL-4 aggravates experimental autoimmune uveoretinitis in rats
84. + T helper type 1 cell responses to Candida albicans
85. H1 cell transfer model of colitis
86. Generation of interferon α-producing predendritic cell (Pre-DC)2 from human CD34(+) hematopoietic stem
87. high) dendritic cells in human nasal allergy